Chandrashekhar, Vishwas G.; Senthamarai, Thirusangumurugan; Kadam, Ravishankar G.; Malina, Ondrej; Kaslik, Josef; Zboril, Radek; Gawande, Manoj B.; Jagadeesh, Rajenahally V.; Beller, Matthias published an article on January 31 ,2022. The article was titled 《Silica-supported Fe/Fe-O nanoparticles for the catalytic hydrogenation of nitriles to amines in the presence of aluminium additives》, and you may find the article in Nature Catalysis.Reference of (2-chloro-3-methylphenyl)methanamine hydrochloride The information in the text is summarized as follows:
The hydrogenation of nitriles to amines represents an important and frequently used industrial process due to the broad applicability of the resulting products in chem. and life sciences. Despite the existing portfolio of catalysts reported for the hydrogenation of nitriles, the development of iron-based heterogeneous catalysts for this process is still a challenge. Here, we show that the impregnation and pyrolysis of iron(II) acetate on com. silica produces a reusable Fe/Fe-O@SiO2 catalyst with a well-defined structure comprising the fayalite phase at the Si-Fe interface and α-Fe nanoparticles, covered by an ultrathin amorphous iron(III) oxide layer, growing from the silica matrix. These Fe/Fe-O core-shell nanoparticles, in the presence of catalytic amounts of aluminum additives, promote the hydrogenation of all kinds of nitriles, including structurally challenging and functionally diverse aromatic, heterocyclic, aliphatic and fatty nitriles, to produce primary amines under scalable and industrially viable conditions. In the experimental materials used by the author, we found (2-chloro-3-methylphenyl)methanamine hydrochloride(cas: 2055841-68-2Reference of (2-chloro-3-methylphenyl)methanamine hydrochloride)
(2-chloro-3-methylphenyl)methanamine hydrochloride(cas: 2055841-68-2) belongs to anime. Aniline, ethanolamines, and several other amines are major industrial commodities used in making rubber, dyes, pharmaceuticals, and synthetic resins and fibres and for a host of other applications. Most of the numerous methods for the preparation of amines may be broadly divided into two groups: (1) chemical reduction (replacement of oxygen with hydrogen atoms in the molecule) of members of several other classes of organic nitrogen compounds and (2) reactions of ammonia or amines with organic compounds.Reference of (2-chloro-3-methylphenyl)methanamine hydrochloride
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics