Gold Catalyzed Decarboxylative Cross-Coupling of Iodoarenes was written by Daley, Ryan A.;Morrenzin, Aaron S.;Neufeldt, Sharon R.;Topczewski, Joseph J.. And the article was included in Journal of the American Chemical Society in 2020.Computed Properties of C7H3ClF2O2 This article mentions the following:
Decarboxylative cross-coupling of (hetero)aryl carboxylates with iodoarenes in the presence of a gold cata-lyst (>25 examples, up to 96% yield) was reported. This reaction was site specific, which overcomes prior limitations associated with gold cat-alyzed oxidative coupling reactions. The reactivity of the (hetero)aryl carboxylate correlated qual. to the field effect pa-rameter (Fortho). Reactions with isolated gold complexes and DFT calculations supported a mechanism proceeding through oxida-tive addition at a gold(I) cation with decarboxylation being viable at either gold(I) or silver(I) species. In the experiment, the researchers used many compounds, for example, 3-Chloro-2,6-difluorobenzoic acid (cas: 225104-76-7Computed Properties of C7H3ClF2O2).
3-Chloro-2,6-difluorobenzoic acid (cas: 225104-76-7) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Computed Properties of C7H3ClF2O2
Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics