Category: 2905-24-0

Chloride substituents modify the physical properties of organic compounds in several ways. 2905-24-0, formula is C6H4BrClO2S, Name is 3-Bromobenzenesulfonyl chloride. They are typically denser than water due to the presence of chlorine, which has a high atomic weight. Electric Literature of 2905-24-0.

Liu, Lixia;Wang, Chengming research published 《 Copper-catalyzed redox-neutral regioselective chlorosulfonylation of vinylarenes》, the research content is summarized as follows. A copper-catalyzed redox-neutral, regioselective aromatic alkene chlorosulfonylation reaction has been developed. This protocol features simple procedure, easily accessible materials and good functional group tolerance. Moreover, it could be amplified to a gram scale and smoothly applied to the late-stage modification of bioactive mol. derivatives

Electric Literature of 2905-24-0, 3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1′ benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.
3-Bromobenzenesulfonyl chloride is a molecule that can be used to inhibit the uptake of 3-bromobenzoate. The inhibition of uptake is due to the desymmetrization of the unsymmetrical, 3-bromobenzoate. This reaction leads to an increase in the concentration of 3-bromobenzoate. Inhibition studies have shown that 3-bromobenzenesulfonyl chloride has an inhibitory effect on cancer cells and apoptosis pathway. The structural studies have shown that this drug is synthetic and biphenyl can be synthesized from it. T-cell lymphomas have been shown to be inhibited by this drug and heart disease has also been inhibited., 2905-24-0.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Organic chlorides are organic molecules with a C-Cl bond, for example chloroform (CH3-Cl) or vinyl chloride(C2H3Cl). 2905-24-0, formula is C6H4BrClO2S, Name is 3-Bromobenzenesulfonyl chloride. Organic chlorides can be used in production of: PVC, Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. Safety of 3-Bromobenzenesulfonyl chloride.

Liu, Ai-Ran;Zhang, Lei;Li, Jiao;Wusiman, Abudureheman research published 《 Catalyst-free one-pot, four-component approach for the synthesis of di- and tri-substituted N-sulfonyl formamidines》, the research content is summarized as follows. A straightforward one-pot, multicomponent approach was developed to synthesize di- and tri-substituted N-sulfonyl formamidines from sulfonyl chlorides, NaN₃, Et propiolate, and primary/secondary amines under mild conditions without catalysts or additives. Structural anal. of the di-substituted sulfonyl formamidines indicated formation of the E-syn/anti isomeric form. Tri-substituted analogs only formed E-isomers.

Safety of 3-Bromobenzenesulfonyl chloride, 3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1′ benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.
3-Bromobenzenesulfonyl chloride is a molecule that can be used to inhibit the uptake of 3-bromobenzoate. The inhibition of uptake is due to the desymmetrization of the unsymmetrical, 3-bromobenzoate. This reaction leads to an increase in the concentration of 3-bromobenzoate. Inhibition studies have shown that 3-bromobenzenesulfonyl chloride has an inhibitory effect on cancer cells and apoptosis pathway. The structural studies have shown that this drug is synthetic and biphenyl can be synthesized from it. T-cell lymphomas have been shown to be inhibited by this drug and heart disease has also been inhibited., 2905-24-0.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Organic chlorides are organic molecules with a C-Cl bond, for example chloroform (CH3-Cl) or vinyl chloride(C2H3Cl). 2905-24-0, formula is C6H4BrClO2S, Name is 3-Bromobenzenesulfonyl chloride. Organic chlorides can be used in production of: PVC, Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. Quality Control of 2905-24-0.

Liu, Jianchen;Dang, Xinxin;Chen, Dan;Zhang, Xinyuan;Yang, Zhonglie;Lin, Li;Jiang, Hezhong;Li, Jiahong research published 《 Hydrolysis of dihydroisoquinoline derivatives activated by sulfonyl or acyl chloride》, the research content is summarized as follows. A new, efficient and mild strategy for hydrolysis of 3,4-dihydroisoquinoline imines activated by sulfonyl chloride or acyl chloride was developed, by which method ketosulfonamides I [R = CF₃, Ph, 4-MeC₆H₄, etc.; R¹ = H, 5-F, 4-MeO, 5-MeO, 6-MeO, 4,5-di-MeO; R² = Ph, 4-Br, 2-NO₂, etc.] and ketoamides II [R³ = Me, Ph, 2-furyl, etc.] were synthesized. This process tolerated broad scope with respect to both the sulfonyl chloride and acyl chloride with moderate to excellent yields. This protocol features a broad substrate scope for various kinds of 3,4-dihydroisoquinoline and mild reaction conditions without using strong acidic or basic conditions. These features showed that this user-friendly and simple system could be applied in the future to the synthesis of a broader range of amino benzophenones.

Quality Control of 2905-24-0, 3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1′ benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.
3-Bromobenzenesulfonyl chloride is a molecule that can be used to inhibit the uptake of 3-bromobenzoate. The inhibition of uptake is due to the desymmetrization of the unsymmetrical, 3-bromobenzoate. This reaction leads to an increase in the concentration of 3-bromobenzoate. Inhibition studies have shown that 3-bromobenzenesulfonyl chloride has an inhibitory effect on cancer cells and apoptosis pathway. The structural studies have shown that this drug is synthetic and biphenyl can be synthesized from it. T-cell lymphomas have been shown to be inhibited by this drug and heart disease has also been inhibited., 2905-24-0.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Organic chlorides are organic molecules with a C-Cl bond, for example chloroform (CH3-Cl) or vinyl chloride(C2H3Cl). 2905-24-0, formula is C6H4BrClO2S, Name is 3-Bromobenzenesulfonyl chloride. Organic chlorides can be used in production of: PVC, Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. Computed Properties of 2905-24-0.

Liu, Lixia;Luo, Bo;Wang, Chengming research published 《 Synthesis of Symmetrical Thiosulfonates via Cu(OTf)₂-Catalyzed Reductive Homocoupling of Arenesulfonyl Chlorides》, the research content is summarized as follows. A variety of sym. thiosulfonates ArSO₂SAr [Ar = 4-MeC₆H₄, 4-ClC₆H₄, 2-thienyl, etc.] were synthesized via Cu-catalyzed reductive homocoupling of aryl sulfonyl chlorides. This protocol used organic amine acting as a mild reductant and low-cost copper as an effective catalyst. Such a reductive coupling process featured a broad substrate scope and good functional group tolerance. Related thiosulfonate products could also be converted into diverse functional mols.

Computed Properties of 2905-24-0, 3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1′ benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.
3-Bromobenzenesulfonyl chloride is a molecule that can be used to inhibit the uptake of 3-bromobenzoate. The inhibition of uptake is due to the desymmetrization of the unsymmetrical, 3-bromobenzoate. This reaction leads to an increase in the concentration of 3-bromobenzoate. Inhibition studies have shown that 3-bromobenzenesulfonyl chloride has an inhibitory effect on cancer cells and apoptosis pathway. The structural studies have shown that this drug is synthetic and biphenyl can be synthesized from it. T-cell lymphomas have been shown to be inhibited by this drug and heart disease has also been inhibited., 2905-24-0.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chlorinated organic compounds are found in nearly every class of biomolecules. 2905-24-0, formula is C6H4BrClO2S, Name is 3-Bromobenzenesulfonyl chloride. Alkyl chlorides, as versatile building blocks in organic chemistry, are used in the preparation of alcohols, thioethers, alkenes, alkynes, esters, and Grignard reagents. SDS of cas: 2905-24-0.

Liu, Lixia;Xue, Pan;Chen, Qiulin;Wang, Chengming research published 《 Copper-Catalyzed Heck-Type Couplings of Sulfonyl Chlorides with Olefins: Efficient and Rapid Access to Vinyl Sulfones》, the research content is summarized as follows. A copper-catalyzed redox-neutral alkenes RCH=CH₂ (R = (tert-butoxy)carbonyl, Ph, thiophen-2-yl, etc.) sulfonylation reaction has been developed. This reported protocol can be easily scale up to a gram scale, and smoothly applied to the late-stage modification of several bioactive mols. I, II, III and IV.

SDS of cas: 2905-24-0, 3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1′ benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.
3-Bromobenzenesulfonyl chloride is a molecule that can be used to inhibit the uptake of 3-bromobenzoate. The inhibition of uptake is due to the desymmetrization of the unsymmetrical, 3-bromobenzoate. This reaction leads to an increase in the concentration of 3-bromobenzoate. Inhibition studies have shown that 3-bromobenzenesulfonyl chloride has an inhibitory effect on cancer cells and apoptosis pathway. The structural studies have shown that this drug is synthetic and biphenyl can be synthesized from it. T-cell lymphomas have been shown to be inhibited by this drug and heart disease has also been inhibited., 2905-24-0.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. 2905-24-0, formula is C6H4BrClO2S, Name is 3-Bromobenzenesulfonyl chloride. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. HPLC of Formula: 2905-24-0.

Li, Yuxiu;Li, Xiangqian;Li, Xiaowei;Shi, Dayong research published 《 Highly E-Selective Synthesis of α-Fluoro-α-arylalkenyl Sulfones from gem-Difluoroalkenes with Sodium Sulfinates》, the research content is summarized as follows. The straightforward synthesis of α-Fluoro-α-arylalkenyl sulfones (E/Z)-RCH=C(F)S(O)₂R¹ (R = naphthalen-2-yl, 1-benzothiophen-3-yl, 3,4-dimethoxyphenyl, etc.; R¹ = 4-methylphenyl, thiophene-2-yl, Pr, etc.) under transition-metal- and base-free conditions have been described, with displays broad functional group compatibility and high stereoselectivity. In particular, the strategy is also applied to the late-stage modification of complex natural products and drugs.

2905-24-0, 3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1′ benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.
3-Bromobenzenesulfonyl chloride is a molecule that can be used to inhibit the uptake of 3-bromobenzoate. The inhibition of uptake is due to the desymmetrization of the unsymmetrical, 3-bromobenzoate. This reaction leads to an increase in the concentration of 3-bromobenzoate. Inhibition studies have shown that 3-bromobenzenesulfonyl chloride has an inhibitory effect on cancer cells and apoptosis pathway. The structural studies have shown that this drug is synthetic and biphenyl can be synthesized from it. T-cell lymphomas have been shown to be inhibited by this drug and heart disease has also been inhibited., HPLC of Formula: 2905-24-0

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chlorinated organic compounds are found in nearly every class of biomolecules. 2905-24-0, formula is C6H4BrClO2S, Name is 3-Bromobenzenesulfonyl chloride. Alkyl chlorides, as versatile building blocks in organic chemistry, are used in the preparation of alcohols, thioethers, alkenes, alkynes, esters, and Grignard reagents. Synthetic Route of 2905-24-0.

Li, Yuxiu;Li, Xiangqian;Li, Xiaowei;Shi, Dayong research published 《 Visible-light-promoted E-selective synthesis of α-fluoro-β-arylalkenyl sulfides via the deoxygenation/isomerization process》, the research content is summarized as follows. Regioselective synthesis of α-fluoro-β-arylalkenyl sulfides (E/Z)-Ar(R¹)C=C(F)SR (R = 4-ClC₆H₄, 2-naphthyl, 2-thienyl, etc.; R¹ = H, CH₃, C₆H₅; Ar = 4-BrC₆H₄, 2-naphthyl, quinolin-3-yl, etc.) has been established with gem-difluoroalkenes Ar(R¹)C=C(F)₂ and sodium sulfinates RS(O)₂Na in a transition-metal-free manner. A series of control experiments was executed to demonstrate thiol radicals and anions as the proposed intermediates. Notably, regioselective Z → E isomerization was achieved under green light irradiation in the absence of a photoinitiator.

2905-24-0, 3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1′ benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.
3-Bromobenzenesulfonyl chloride is a molecule that can be used to inhibit the uptake of 3-bromobenzoate. The inhibition of uptake is due to the desymmetrization of the unsymmetrical, 3-bromobenzoate. This reaction leads to an increase in the concentration of 3-bromobenzoate. Inhibition studies have shown that 3-bromobenzenesulfonyl chloride has an inhibitory effect on cancer cells and apoptosis pathway. The structural studies have shown that this drug is synthetic and biphenyl can be synthesized from it. T-cell lymphomas have been shown to be inhibited by this drug and heart disease has also been inhibited., Synthetic Route of 2905-24-0

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. 2905-24-0, formula is C6H4BrClO2S, Name is 3-Bromobenzenesulfonyl chloride. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Name: 3-Bromobenzenesulfonyl chloride.

Li, Guodong;Kong, Xianqiang;Liang, Qi;Lin, Long;Yu, Ke;Xu, Bo;Chen, Qianjin research published 《 Metal-Free Electrochemical Coupling of Vinyl Azides: Synthesis of Phenanthridines and β-Ketosulfones》, the research content is summarized as follows. The authors reported an efficient and environmentally benign electrochem. synthesis of phenanthridines by oxidative coupling of vinyl azides with sodium azide or benzenesulfonyl hydrazides, for the first time. The reaction conditions are mild, and no addnl. metal-catalyst or exogenous oxidants are needed. The protocol has broad substrate scope and high functional group tolerance. Furthermore, this green electrochem. procedure can be readily extended to the synthesis of β-ketosulfones. Gram scale reactions further demonstrate the practicability.

2905-24-0, 3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1′ benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.
3-Bromobenzenesulfonyl chloride is a molecule that can be used to inhibit the uptake of 3-bromobenzoate. The inhibition of uptake is due to the desymmetrization of the unsymmetrical, 3-bromobenzoate. This reaction leads to an increase in the concentration of 3-bromobenzoate. Inhibition studies have shown that 3-bromobenzenesulfonyl chloride has an inhibitory effect on cancer cells and apoptosis pathway. The structural studies have shown that this drug is synthetic and biphenyl can be synthesized from it. T-cell lymphomas have been shown to be inhibited by this drug and heart disease has also been inhibited., Name: 3-Bromobenzenesulfonyl chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 2905-24-0, formula is C6H4BrClO2S, Name is 3-Bromobenzenesulfonyl chloride. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. COA of Formula: C6H4BrClO2S.

Lemke, Carina;Cianni, Lorenzo;Feldmann, Christian;Gilberg, Erik;Yin, Jiafei;dos Reis Rocho, Fernanda;de Vita, Daniela;Bartz, Ulrike;Bajorath, Juergen;Montanari, Carlos A.;Guetschow, Michael research published 《 N-Sulfonyl dipeptide nitriles as inhibitors of human cathepsin S: In silico design, synthesis and biochemical characterization》, the research content is summarized as follows. A library of cathepsin S inhibitors of the dipeptide nitrile chemotype, bearing a bioisosteric sulfonamide moiety, was synthesized. Kinetic investigations were performed at four human cysteine proteases, i.e. cathepsins S, B, K and L. Compound (I) with a terminal 3-biphenyl sulfonamide substituent was the most potent (K_i = 4.02 nM; selectivity ratio cathepsin S/K = 5.8; S/L = 67) and (II) with a 4′-fluoro-4-biphenyl sulfonamide substituent the most selective cathepsin S inhibitor (K_i = 35.5 nM; selectivity ratio cathepsin S/K = 57; S/L = 31). In silico design and biochem. evaluation emphasized the impact of the sulfonamide linkage on selectivity and a possible switch of P2 and P3 substituents with respect to the occupation of the corresponding binding sites of cathepsin S.

COA of Formula: C6H4BrClO2S, 3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1′ benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.
3-Bromobenzenesulfonyl chloride is a molecule that can be used to inhibit the uptake of 3-bromobenzoate. The inhibition of uptake is due to the desymmetrization of the unsymmetrical, 3-bromobenzoate. This reaction leads to an increase in the concentration of 3-bromobenzoate. Inhibition studies have shown that 3-bromobenzenesulfonyl chloride has an inhibitory effect on cancer cells and apoptosis pathway. The structural studies have shown that this drug is synthetic and biphenyl can be synthesized from it. T-cell lymphomas have been shown to be inhibited by this drug and heart disease has also been inhibited., 2905-24-0.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Organic chlorides are organic molecules with a C-Cl bond, for example chloroform (CH3-Cl) or vinyl chloride(C2H3Cl). 2905-24-0, formula is C6H4BrClO2S, Name is 3-Bromobenzenesulfonyl chloride. Organic chlorides can be used in production of: PVC, Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. Related Products of 2905-24-0.

Kong, Yuan;Yi, Yong-Jia;Liu, Xiao-Qing;Yu, Pan;Zhao, Lin-Guo;Li, Dong-Dong research published ã€?Discovery and structural optimization of 9-O-phenylsulfonyl-berberines as new lipid-lowering agentsã€? the research content is summarized as follows. In this study, a focused berberine-like compound library containing 12,600 mols. was built via the introduction of various “drug-like” fragments at the C8 and C9 positions of berberine. Sixteen compounds were hit by using the inhouse QSAR models previously reported by our group. Considering synthesis feasibility and the cost of building-blocks, only four berberine analogs were selected and synthesized for investigating their lipid-lowering activities. A preliminary lipid-lowering study showed that compound I with the phenylsulfonyl group at the C9 position had potent cholesterol inhibitory activity in HepG2 cells, superior to that of the parent compound berberine. Subsequently, a total of twenty-five 9-O-phenylsulfonyl-berberines II (R¹ = H, F, Cl, NO₂, Me, R² = H, F, Cl, CF₃, NO₂, R³ = H, Cl, F, Br, NO₂, Me, OMe, R⁴ = H, CF₃, Cl, R⁵ = H, F, Me) and twenty-four 9-O-phenylsulfonyl-tetrahydroberberine III (R¹ = H, F, Cl, NO₂, CHMe₂, R² = H, F, Cl, Br, NO₂, CF₃, R³ = H, F, Cl, Br, NO₂, Me, OMe, tert-Bu, CHMe₂, R⁴ = H, Cf₃, R⁵ = H, CHMe₂) were designed, synthesized, and evaluated by lipid-lowering experiments The results showed that most compounds exhibited more lipid-lowering activities than berberine. Among them, compound II (R¹ = R³ = R⁴ = R⁵ = H, R² = CF₃) (IV) inhibited cholesterol production close to 50% in both cell models when compared with the blank control; the inhibition of triglycerides exceeded 70%. Moreover, IV also had significant pharmacol. effects on the inhibition of LDLC and promotion of HDLC production, especially in the HepG2 cell model, in which the inhibitory rate against LDLC was close to 70% and the increase rate of HDLC was more than 75%. The hypolipidemic experiment of SD rats demonstrated that after 40 days of administration IV (15 mg/kg/d), blood cholesterol was reduced by 19.6%, triglycerides were reduced by 34.52%, and LDLC was reduced by 41.49%, when compared with the high-fat diet model (HFD). In addition, after 80 days of administration, the three indexes of IV were still better than that of berberine. Oil Red O staining and H&E staining results showed that IV exhibited potent lipid scavenging activity. All in all, IV was discovered and identified as a potent lipid-lowering agent and a new berberine-like candidate, being evaluated by subsequent studies.

2905-24-0, 3-Bromobenzenesulfonyl chloride is an aryl sulfonyl chloride derivative. It participates in the synthesis of N-sulfonylanthranilic acid derivatives and potent P1�benzenesulfonyl azacyclic urea human immunodeficiency virus (HIV) protease inhibitors.
3-Bromobenzenesulfonyl chloride is a molecule that can be used to inhibit the uptake of 3-bromobenzoate. The inhibition of uptake is due to the desymmetrization of the unsymmetrical, 3-bromobenzoate. This reaction leads to an increase in the concentration of 3-bromobenzoate. Inhibition studies have shown that 3-bromobenzenesulfonyl chloride has an inhibitory effect on cancer cells and apoptosis pathway. The structural studies have shown that this drug is synthetic and biphenyl can be synthesized from it. T-cell lymphomas have been shown to be inhibited by this drug and heart disease has also been inhibited., Related Products of 2905-24-0

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics