Category: 320-50-3

Adding a certain compound to certain chemical reactions, such as: 320-50-3, name is 1,4-Dichloro-2-(trifluoromethyl)benzene, belongs to chlorides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 320-50-3, Safety of 1,4-Dichloro-2-(trifluoromethyl)benzene

Take 2,5-dichloro-3-trifluoromethylbenzene 6 (15.4 g) in an autoclave,Hydrazine hydrate (26g) and pyridine (150ml) were added together with ethyl acetate and methylene chloride (250ml) as organic solvents. The mixture was heated to 130C and reacted for 4 hours. After cooling, excess hydrazine was removed, vacuum distillation was performed, and the residue was added with solvent petroleum. The ether is recrystallized to give 2-chloro-3-trifluoromethylphenylhydrazine 7 (12.1 g)

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Reference:
Patent; Wei Haixia; Du Caixia; Hou Yingchang; (7 pag.)CN107915676; (2018); A;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Reference of 320-50-3, The chemical industry reduces the impact on the environment during synthesis 320-50-3, name is 1,4-Dichloro-2-(trifluoromethyl)benzene, I believe this compound will play a more active role in future production and life.

EXAMPLE 8 4-Chloro-2-trifluoromethylphenol To a 300 ml, 3-necked flask fitted with a stirrer, condenser, thermometer and drying tube is added dimethylsulfoxide (100 ml), tert-butanol (20 ml), powdered potassium hydroxide (KOH) pellets (85%, 30 g) and 2,5-dichlorobenzotrifluoride (21.5 g, 0.10 mole). The reaction mixture is warmed to 71-73 C. for 60 hours, then additional KOH (10 g) is added and heating is continued at 73-75 C. for 24 hours. The reaction mixture is cooled and the solvent partially removed by distillation at 0.9 mm, bp 55 C.). The cooled pot residue is then poured into ice water (1000 g) which had been preacidified to pH 1 with conc. HCl (50 ml). The aqueous mixture is extracted with carbon tetrachloride (CCl4), the CCl4 layer decanted and dried and the solvent removed under vacuum to afford 10.8 g of 4-chloro-2-trifluoromethylphenol, which is sublimed to afford pure product, mp 81-81.5 C. Elemental Anal. Calcd for C7 H4 ClF3 O: C, 42.75; H, 2.06; Cl, 18.04: Found: C, 42.54; H, 2.36; Cl, 18.16. STR14

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,4-Dichloro-2-(trifluoromethyl)benzene, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Rohm and Haas Company; US4259510; (1981); A;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Adding a certain compound to certain chemical reactions, such as: 320-50-3, name is 1,4-Dichloro-2-(trifluoromethyl)benzene, belongs to chlorides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 320-50-3, Quality Control of 1,4-Dichloro-2-(trifluoromethyl)benzene

Similarly, 4-(2-trifluoromethyl-4-chlorophenoxy)benzene is prepared by following the same procedure but using 1,4-dichloro-2-trifluoromethylbenzene in place of 1,2-dichloro-4-trifluoromethylbenzene.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,4-Dichloro-2-(trifluoromethyl)benzene, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Chevron Research Company; US4287213; (1981); A;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Application of 320-50-3, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 320-50-3 as follows.

Similarly, 4-(2-trifluoromethyl-4-chlorophenoxy)benzene is prepared by following the same procedure but using 1,4-dichloro-2-trifluoromethylbenzene in place of 1,2-dichloro-4-trifluoromethylbenzene.

According to the analysis of related databases, 320-50-3, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Chevron Research; US4289909; (1981); A;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics