Category: 3240-10-6

He, Dandan; Zhong, Wentao; Zhou, Miaomiao; Wang, Bowen; Li, Meng; Jiang, Huanfeng; Wu, Wanqing published the artcile< Palladium-Catalyzed Regio- and Stereoselective Coupling of Alkynylsulfones with Alkenes: Access to Dichlorinated Vinyl Sulfones>, Electric Literature of 3240-10-6, the main research area is dichlorinated vinyl sulfone regioselective preparation diastereoselective; alkynylsulfone ester coupling palladium catalyst; alkene alkynylsulfone coupling palladium catalyst.

A palladium-catalyzed coupling reaction of alkynylsulfones with alkenes/ester was described, which provided an efficient and practical entry to various functionalized dichlorinated vinyl sulfones I [R1 = H, 4-Me, 3-F, etc.; R2 = Me, Ph, 4-ClC6H4, etc.]. This method featured excellent regio- and stereoselectivities, good functional group compatibility, as well as mild reaction conditions.

Organic Letters published new progress about Aryl alkenes Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 3240-10-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H5ClO2, Electric Literature of 3240-10-6.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Zhang, Wei; Mei, Yu; Huang, Xiao; Wu, Peng; Wu, Haihong; He, Mingyuan published the artcile< Size-Controlled Growth of Silver Nanoparticles onto Functionalized Ordered Mesoporous Polymers for Efficient CO2 Upgrading>, SDS of cas: 3240-10-6, the main research area is silver nanoparticle catalyst functionalized mesoporous polymer carbon dioxide; CO2 carboxylation; heterogeneous catalysis; mesoporous materials; monodispersed silver; size-controlled synthesis.

Highly dispersed metallic Ag nanoparticles (AgNPs) are promising heterogeneous catalysts for carboxylative coupling of terminal alkynes with CO2 under mild conditions. Yet their size-controlled synthesis is very challenging due to the high surface energy. Here the authors prepared amino-functionalized ordered mesoporous polymers as hosts for anchoring AgNPs. Control experiments and computations showed that electron-rich amines confined in mesochannels with varying electron d. and steric hindrance, creating localized active zones (LAZ) to control the growth of AgNPs. The particle size of AgNPs grows along with the increased volume of LAZ around nitrogen species. The authors also revealed that the catalytic activity of Ag-based catalysts is size-dependent and increases with decreasing particle size. Building on these findings, the authors report a facile 1-pot synthesis strategy for preparing amine-incorporated ordered mesoporous polymer (NOMP) with a high sp. surface area, small LAZ volume, and uniform amine sites with controllable loading. These features gave ultrasmall and monodispersed Ag nanoparticles. Remarkably, Ag@NOMP gave a quant. target yield under the conditions of 1 atm CO2 pressure and 50°, showing superior catalytic activity in the CO2 carboxylation compared to other mesoporous analogs.

ACS Applied Materials & Interfaces published new progress about Carboxylation catalysts. 3240-10-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H5ClO2, SDS of cas: 3240-10-6.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Shi, Jun-Bin; Bu, Qingqing; Liu, Bin-Yuan; Dai, Bin; Liu, Ning published the artcile< Organocatalytic Strategy for the Fixation of CO2 via Carboxylation of Terminal Alkynes>, Quality Control of 3240-10-6, the main research area is propiolic acid preparation; terminal alkyne carbon dioxide carboxylation organocatalyst.

An organocatalytic strategy for the direct carboxylation of terminal alkynes with CO2 had been developed. The combined use of a bifunctional organocatalyst and Cs2CO3 resulted in a robust catalytic system for the preparation of a range of propiolic acid derivatives RC≡CCOOH [R = t-Bu, Ph, 2-thienyl, etc.] in high yields with broad substrate scope using CO2 at atm. pressure under mild temperatures (60°C). This work had demonstrated that this organocatalytic method offered a competitive alternative to metal catalysis for the carboxylation of terminal alkynes and CO2. In addition, this protocol was suitable for the three-component carboxylation of terminal alkynes, alkyl halides and CO2.

Journal of Organic Chemistry published new progress about Alkynes, α- Role: RCT (Reactant), RACT (Reactant or Reagent). 3240-10-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H5ClO2, Quality Control of 3240-10-6.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Yesmin, Sabina; Abbas, Sk Jahir; Ke, Shyue-Chu published the artcile< A powerful and multifunctional catalyst for organic synthesis, transformation, and environmental remediation: A polyImidazole supported trimetallic catalyst>, Quality Control of 3240-10-6, the main research area is polyImidazole trimetallic catalyst organic synthesis environmental remediation.

We have constructed a state-of-the-art polyimidazole-supported trimetallic composite, PIm/FeZnAg, for organic synthesis, transformation, and environmental remediation on a single platform. The sustainable chem. of organic reactions involving three-component coupling, CO2 insertion, [3 + 2]-click, Knoevenagel condensation, and CO2 cycloaddition reactions, and environmental pollutant reduction and bacterial inhibition are performed to comprehensively evaluate the power of this multifunctional catalyst. Most reactions withstand good functional group tolerance, producing forty-one derivatives with molecularly distinct moieties at good to near-quant. yields under benign reaction conditions. Full chem., microscopic, and structural characterizations reveal that metallic Ag, ZnO, and Fe2O3 with well-defined nanostructures are well interspersed and integrated on the PIm support. The metallic centers provide a conjugated multivalent architecture that work synergistically on a platform with moderate surface area and good CO2 adsorption capacity is the key to the multi-functionalities and effectiveness of PIm/FeZnAg, which is a current demand for developing green sustainable heterogeneous catalysts.

Applied Catalysis, B: Environmental published new progress about Adsorption. 3240-10-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H5ClO2, Quality Control of 3240-10-6.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Reddy, Chada Raji; Kolgave, Dattahari H.; Subbarao, Muppidi; Aila, Mounika; Prajapti, Santosh Kumar published the artcile< Ag-Catalyzed Oxidative ipso-Cyclization via Decarboxylative Acylation/Alkylation: Access to 3-Acyl/Alkyl-spiro[4.5]trienones>, Quality Control of 3240-10-6, the main research area is spirotrienone preparation; pyrroloquinoline dione preparation; arylpropiolamide acid tandem decarboxylative acylation alkylation cyclization silver catalyst.

A strategy to functionalized spiro[4.5]trienones I [R = Ph, 2-thienyl, 1-naphthyl, etc.; R1 = Me, Bn, Ts, etc.; R2 = H, 7-Me, 7-F, etc.; R3 = Me, C(O)Me, C(O)Ph, etc.] by domino silver-catalyzed decarboxylative acylation or alkylation/ipso-cyclization of N-arylpropiolamides with α-keto acids/alkyl carboxylic acids was presented. This transformation offered a wide range of substituted 3-acyl/alkyl-spiro[4.5]trienones in high yields with a broad substrate scope. The approach was further extended to access fused tricyclic frameworks, 6,7-dihydro-3H-pyrrolo[2,1-j]quinoline-3,9(5H)-diones II [R4 = Ph, 4-ClC6H4, 4-AcC6H4; R5 = t-Bu, C(O)Et, C(O)Ph, etc.].

Organic Letters published new progress about Acylation. 3240-10-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H5ClO2, Quality Control of 3240-10-6.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Bu, Ran; Zhang, Lin; Gao, Lu-Lu; Sun, Weng-Jie; Yang, Shuai-Liang; Gao, En-Qing published the artcile< Copper(I)-modified covalent organic framework for CO2 insertion to terminal alkynes>, Electric Literature of 3240-10-6, the main research area is carbon dioxide insertion alkyne catalyzed copper covalent organic framework.

The carboxylation of terminal alkynes with CO2 is an attractive route for CO2 fixation and conversion, and various homogeneous Cu(I) catalysts were explored for the reaction. However, it is still a challenge to develop efficient heterogeneous catalysts for the conversion under mild conditions. Considering that covalent organic frameworks (COFs) are emerging as versatile platforms for the design of functional materials, the authors developed a TpBpy-supported Cu(I) catalyst, where TpBpy is a stable imine-type porous COF furnished with rich N,N- and N,O-chelating sites for Cu(I) immobilization. The hybrid material can efficiently catalyze the conversion of CO2 and terminal alkynes to propiolic acids under relatively mild conditions (1 atm CO2, 60°). The catalytic activity arises from the synergy between the organic framework of TpBpy and the Cu(I) sites. Not merely serving as a porous support to afford isolated and accessible Cu(I) sites, the organic framework itself has its own catalytic activity through the polar and basic N and O functional sites, which could activate the C-H bond and facilitate CO2 absorption. The framework also serves as a giant ligand to shift the reversible Cu(I)-catalyzed process in favor of carboxylation. The catalyst shows somewhat reduced activity after reused for three cycles owing to the oxidation of Cu(I) to Cu(II), but it can be easily regenerated by treating with KI.

Molecular Catalysis published new progress about Alkynes, α- Role: RCT (Reactant), RACT (Reactant or Reagent). 3240-10-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H5ClO2, Electric Literature of 3240-10-6.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Shang, Jia-Qi; Fu, Hong; Li, Yi; Yang, Tao; Gao, Chuanzhu; Li, Ya-Min published the artcile< Copper-catalyzed decarboxylation/cycloaddition cascade of alkynyl carboxylic acids with azide>, Safety of 3-(4-Chlorophenyl)propiolic acid, the main research area is copper catalyzed decarboxylation cycloaddition cascade alkynoic acid azide; triazole synthesis decarboxylation cycloaddition cascade alkynoic acid azide.

A copper-catalyzed decarboxylation/cycloaddition cascade of alkynyl carboxylic acids with azide has been developed [e.g., phenylpropiolic acid + (azidomethyl)trimethylsilane → 4-phenyl-1-[(trimethylsilyl)methyl]-1H-1,2,3-triazole (97%) in presence of Cu2O in MeCN]. This reaction exhibits good functional group tolerance and wide substrate scope, provides an efficient way to construct 1,4-disubstituted 1,2,3-triazoles.

Tetrahedron published new progress about 1,3-Dipolar cycloaddition reaction. 3240-10-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H5ClO2, Safety of 3-(4-Chlorophenyl)propiolic acid.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Li, Qingrui; Yin, Yunnian; Li, Yabo; Zhang, Jianye; Huang, Mengmeng; Kim, Jung Keun; Wu, Yangjie published the artcile< A simple approach to indeno-coumarins via visible-light-induced cyclization of aryl alkynoates with diethyl bromomalonate>, Product Details of C9H5ClO2, the main research area is indenochromene preparation regioselective; aryl alkynoate diethyl bromomalonate cyclization reaction photocatalyst.

Visible-light-induced triple-domino cyclization between aryl alkynoates R1C6H4OC(O)CCC6H4R2 (R1 = H, 2-Cl, 3-tert-Bu, etc.; R2 = H, 4-Me, 4-Cl, 4-F, 4-OMe) and di-Et bromomalonate was developed for the synthesis of indeno-coumarins I (R3 = H, 1-Cl, 4-tert-Bu, 2-tert-Bu, etc.; R4 = H, 9-Me, 9-F, 9-Cl, 9-MeO). This one-pot method substantially simplified the production process for indeno-coumarins I and a series of indeno-coumarins could be isolated in moderate to high yields. It was found that the obtained indeno-coumarins I could be used as addnl. photosensitizers to initiate this transformation. A possible radical mechanism accompanying the processes of electron transfer and energy transfer is proposed based on the results of ESI-MS anal., cyclic voltammetry, Stern-Volmer quenching experiments and control experiments The photoluminescence properties (emission spectra and quantum yields) of the obtained indeno-coumarins I were investigated.

Organic Chemistry Frontiers published new progress about Alkynes, aryl Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 3240-10-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H5ClO2, Product Details of C9H5ClO2.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Du, Xiaochen; Yu, Jiafeng; Gong, Jing; Zaman, Manzoor; Pereshivko, Olga P.; Peshkov, Vsevolod A. published the artcile< Gold-Catalyzed Post-Ugi Cascade Transformation for the Synthesis of 2-Pyridones>, Electric Literature of 3240-10-6, the main research area is propiolic acid isocyanide aldehyde aniline Ugi one pot; bisamide preparation; furan alkyne cyclization ring opening cleavage gold catalyst diastereoselective; pyridone stereoselective cascade preparation.

A gold-catalyzed post-Ugi cascade transformation for the synthesis of 2-pyridones is described. The process involves furan-alkyne cyclization followed by furan ring-opening and cleavage of the isocyanide-originated fragment. The initially formed cis double bond can isomerize into a more stable trans double bond, e.g. I, upon prolonged exposure to a strong Bronsted acid. Thus, the overall strategy provides a viable access towards two types of 2-pyridones.

European Journal of Organic Chemistry published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 3240-10-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H5ClO2, Electric Literature of 3240-10-6.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Li, Yi; Shang, Jia-Qi; Wang, Xiang-Xiang; Xia, Wen-Jin; Yang, Tao; Xin, Yangchun; Li, Ya-Min published the artcile< Copper-Catalyzed Decarboxylative Oxyalkylation of Alkynyl Carboxylic Acids: Synthesis of γ-Diketones and γ-Ketonitriles>, Synthetic Route of 3240-10-6, the main research area is arylalkynylcarboxylic acid ketone nitrile decarboxylative oxyalkylation; diketone preparation; ketonitrile preparation; copper decarboxylative oxyalkylation catalyst.

A copper-catalyzed decarboxylative oxyalkylation of alkynylcarboxylic acids with ketones and alkylnitriles via direct C(sp3)-H bond functionalization to construct new C-C bonds and C-O double bonds was developed. This transformation is featured by wide functional group compatibility and the use of readily available reagents, thus affording a general approach to γ-diketones and γ-ketonitriles. A possible mechanism is proposed.

Organic Letters published new progress about Alkylation catalysts (decarboxylative oxy-). 3240-10-6 belongs to class chlorides-buliding-blocks, and the molecular formula is C9H5ClO2, Synthetic Route of 3240-10-6.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics