Category: 3386-33-2

Mechanism-Based QSAR Modeling of Skin Sensitization was written by Dearden, J. C.;Hewitt, M.;Roberts, D. W.;Enoch, S. J.;Rowe, P. H.;Przybylak, K. R.;Vaughan-Williams, G. D.;Smith, M. L.;Pillai, G. G.;Katritzky, A. R.. And the article was included in Chemical Research in Toxicology in 2015.Recommanded Product: 1-Chlorooctadecane This article mentions the following:

Many chems. can induce skin sensitization, and there is a pressing need for non-animal methods to give a quant. indication of potency. Using two large published data sets of skin sensitizers, we have allocated each sensitizing chem. to one of 10 mechanistic categories and then developed good QSAR models for the seven categories that have a sufficient number of chems. to allow modeling. Both internal and external validation checks showed that each model had good predictivity. In the experiment, the researchers used many compounds, for example, 1-Chlorooctadecane (cas: 3386-33-2Recommanded Product: 1-Chlorooctadecane).

1-Chlorooctadecane (cas: 3386-33-2) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Recommanded Product: 1-Chlorooctadecane

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Effect of exogenous nitric oxide on the volatile components in the petals of peony was written by Wang, Juan. And the article was included in Henong Xuebao in 2014.Recommanded Product: 3386-33-2 This article mentions the following:

To explore the effect of exogenous nitric oxide on volatile components in the petals of peony, 0.2 mmol路L^-1 nitric oxide (NO) donor sodium nitroprusside (SNP) was used to spray whole plant leaves in bud stage. SPME-GC-MS was used to determine the volatile components in petals of tree peony. Sixty-two kinds of volatile components were detected in the different blooming stages of peony and SNP treatment, including alkanes, terpenes, arenes, alcs., esters, ketones and heterocycles. Alkanes and terpenes were the most volatile components, and the most was at full bloom stage. Exogenous NO treatment reduced the types of alkanes, alcs. and early arenes at the petals of all blooming stages. There was no evident impact on the terpenes and ketones with esters wasn’t detected. NO treatment increased the alkanes content at full-bloom stage, decreased the contents of the terpenes, alcs. and arenes at the beginning bloom stage. Therefore, the type and content of volatile component were influenced by exogenous NO in petals of tree peony at different flowering stages. There was most influence at full blooming stage, followed by the beginning bloom stage. The impact on the end bloom stage was the min. This study will provide certain theor. basis for the development and utilization of peony flower. In the experiment, the researchers used many compounds, for example, 1-Chlorooctadecane (cas: 3386-33-2Recommanded Product: 3386-33-2).

1-Chlorooctadecane (cas: 3386-33-2) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Recommanded Product: 3386-33-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Effect of exogenous nitric oxide on the volatile components in the petals of peony was written by Wang, Juan. And the article was included in Henong Xuebao in 2014.Recommanded Product: 3386-33-2 This article mentions the following:

To explore the effect of exogenous nitric oxide on volatile components in the petals of peony, 0.2 mmol·L^-1 nitric oxide (NO) donor sodium nitroprusside (SNP) was used to spray whole plant leaves in bud stage. SPME-GC-MS was used to determine the volatile components in petals of tree peony. Sixty-two kinds of volatile components were detected in the different blooming stages of peony and SNP treatment, including alkanes, terpenes, arenes, alcs., esters, ketones and heterocycles. Alkanes and terpenes were the most volatile components, and the most was at full bloom stage. Exogenous NO treatment reduced the types of alkanes, alcs. and early arenes at the petals of all blooming stages. There was no evident impact on the terpenes and ketones with esters wasn’t detected. NO treatment increased the alkanes content at full-bloom stage, decreased the contents of the terpenes, alcs. and arenes at the beginning bloom stage. Therefore, the type and content of volatile component were influenced by exogenous NO in petals of tree peony at different flowering stages. There was most influence at full blooming stage, followed by the beginning bloom stage. The impact on the end bloom stage was the min. This study will provide certain theor. basis for the development and utilization of peony flower. In the experiment, the researchers used many compounds, for example, 1-Chlorooctadecane (cas: 3386-33-2Recommanded Product: 3386-33-2).

1-Chlorooctadecane (cas: 3386-33-2) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Recommanded Product: 3386-33-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Comparative antioxidant, anticancer and antimicrobial activities of essential oils from Semen Platycladi by different extraction methods was written by Zhu, Jing-Jing;Yang, Jing-Juan;Wu, Guo-Jie;Jiang, Jian-Guo. And the article was included in Industrial Crops and Products in 2020.Recommanded Product: 1-Chlorooctadecane This article mentions the following:

Semen Platycladi is a highly valued seed tonic from the Cupressaceae Platycladus orientalis (L.) Franco, which contains abundant essential oils exhibiting antioxidant, antimicrobial, sedative and hypnotic potency. The study was formulated to estimate the potential antioxidant, anticancer and antibacterial activities of its essential oils as well as its correlation with chem. constituents. The comparison of three isolation methods including steam distillation extraction, heating reflux extraction, and Soxhlet extraction of ethanol was carried out to isolate essential oils whose chem. composition were identified and evaluated by Gas Chromatog.-Mass Spectrometer. It turned out that the yield of essential oils obtained through heating reflux extraction and Soxhlet extraction was almost 40 % higher than those extracted by steam distillation extraction in nearly one-quarter of a time used by the steam distillation extraction A total of 76 compounds were identified, including ten alkanes, 14 alkenes, 13 alcs., one aldehyde ketone, three ethers, one acid, 17 esters, five aromatic compounds, and 12 others. The essential oils extracted by steam distillation extraction were proved to have the best antioxidant and antimicrobial activity although with the lowest yield. Scanning electron microscopic observation displayed that the of S. aureus revealed serious disruption of cell membranes resulting in the loss of cell viability. Therefore, it′s vital to adopt a proper method to obtain the target ingredients recommended as nutraceuticals and/or phytomedicines. In the experiment, the researchers used many compounds, for example, 1-Chlorooctadecane (cas: 3386-33-2Recommanded Product: 1-Chlorooctadecane).

1-Chlorooctadecane (cas: 3386-33-2) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Recommanded Product: 1-Chlorooctadecane

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Determination of Cadmium in Tap, Sea and Waste Water Samples by Vortex-Assisted Dispersive Liquid-Liquid-Solidified Floating Organic Drop Microextraction and Slotted Quartz Tube FAAS After Complexation with a Imidazole Based Ligand was written by Findikoglu, Maral Selin;Firat, Merve;Chormey, Dotse Selali;Turak, Fatma;Sahin, Cigdem;Bakirdere, Sezgin. And the article was included in Water, Air, & Soil Pollution in 2018.SDS of cas: 3386-33-2 This article mentions the following:

This study presents a combination of dispersive liquid-liquid-solidified floating organic drop microextraction (DLLSFODM) and slotted quartz tube (SQT) with conventional flame at. absorption spectrometry (FAAS) to improve the sensitivity for cadmium determination A ligand namely 2-(4-methylphenyl)-1H-imidazo-[4,5-f]-[1,10]-phenanthroline which has not been used in trace analyte determination was used to form a cadmium complex. Stepwise optimization of parameters affecting complex formation (pH, ligand, and buffer solution) and extraction (extraction and dispersive solvents, salt effect and mixing) was done to maximize cadmium absorbance. The slotted quartz tube was fitted onto the flame burner and optimized to increase residence time of atoms in the flame. Instrumental parameters such as sample and fuel flow rate were also optimized to further enhance the absorbance signal for cadmium. Using optimal parameters and values, the limits of detection and quantification were determined to be 0.81 and 2.69 μg L^-1, resp. Low percent relative standard deviations (< 6.0%) indicated good precision for both extraction and instrumental measurements. Recovery tests were used to determine the accuracy of the method and the recovery results obtained were between 88 and 113%. [Figure not available: see fulltext.]. In the experiment, the researchers used many compounds, for example, 1-Chlorooctadecane (cas: 3386-33-2SDS of cas: 3386-33-2).

1-Chlorooctadecane (cas: 3386-33-2) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.SDS of cas: 3386-33-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Sialic acid conjugate-modified liposomes enable tumor homing of epirubicin via neutrophil/monocyte infiltration for tumor therapy was written by Ding, Junqiang;Sui, Dezhi;Liu, Mingqi;Su, Yuqing;Wang, Yang;Liu, Mengyang;Luo, Xiang;Liu, Xinrong;Deng, Yihui;Song, Yanzhi. And the article was included in Acta Biomaterialia in 2021.Recommanded Product: 1-Chlorooctadecane This article mentions the following:

Neutrophils and monocytes (N/Ms) are potential candidates for the delivery of therapeutic agents to the tumor microenvironment (TME) because of their tumor-accumulating nature. L-selectin and Siglec-1, receptors for sialic acid (SA), are highly expressed in circulating neutrophils and monocytes, resp., in tumor-bearing mice, and N/Ms are recruited to tumors in response to inflammatory cytokines secreted by the TME, promoting tumor growth and invasion. Therefore, we constructed a drug delivery nano-platform using N/Ms as vehicles. SA-stearic acid conjugate was synthesized and utilized to modify epirubicin-loaded liposomes (EPI-SL) for enhanced endocytosis of liposomes by circulating N/Ms. Cellular uptake studies showed that SA modification improved the accumulation of EPI in N/Ms and did not alter the inherent chemotaxis of N/Ms. In tumor-bearing mice, EPI-SL significantly improved the tumor-targeting efficiency and therapeutic efficacy of EPI compared to other preparations and even eradicated tumors because of the tumor-accumulating and inhibitory effects of N/Ms containing EPI-SL. Our research showed, for the first time, that as an N/M-based drug delivery platform, EPI-SL remedied the limited tumor targeting in the conventional EPR effect-based treatment strategy, contributing to the exploitation of a new drug delivery platform for cancer treatment. In the experiment, the researchers used many compounds, for example, 1-Chlorooctadecane (cas: 3386-33-2Recommanded Product: 1-Chlorooctadecane).

1-Chlorooctadecane (cas: 3386-33-2) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Recommanded Product: 1-Chlorooctadecane

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Effect of different drying techniques on the volatile compounds, morphological characteristics and thermal stability of Stevia rebaudiana Bertoni leaf was written by Gasmalla, Mohammed Abdalbasit A.;Tessema, Habtamu A.;Alahmed, Kamal;Hua, Xiao;Liao, Xiangru;Yang, Ruijin. And the article was included in Tropical Journal of Pharmaceutical Research in 2017.Related Products of 3386-33-2 This article mentions the following:

Purpose: To examine the volatile compounds, thermal stability and morphol. characteristics of stevia (Stevia rebaudiana Bertoni) leaves after sun, oven and microwave drying. Methods: Gas chromatog.-mass spectrometry with a spectral anal. manager was used to sep. the volatile compounds Dried stevia leaf powder was characterized morphol. by SEM while thermal properties were determined by differential scanning calorimetry (DSC). Results: The plant material contained large amounts of spathulenol and caryophyllene oxide. The main compounds were 1-docosanol and hexanoic acid; trans-β-ionone, 5-methylundecane, 2,5,6- trimethyldecane, (+) spathulenol, propanoic acid and 1-chlorononadecane. The surface of the dried leaf powder varied with the treatment applied. Following microwave drying, the particles were even, regular, and compact while the sun- and oven dried particles resembled angular bricks. All samples exhibited a strong endothermic response, indicating stability up to 150 °C; from 150 to 200 °C, thermal decomposition occurred. Conclusion: Drying method has a significant effect on the structure, thermal stability and volatile compounds contents of stevia leaves. All drying methods examined in this study have potential applications in the preparation of stevia as a functional ingredient for the food and pharmaceutical industries. In the experiment, the researchers used many compounds, for example, 1-Chlorooctadecane (cas: 3386-33-2Related Products of 3386-33-2).

1-Chlorooctadecane (cas: 3386-33-2) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Related Products of 3386-33-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics