Category: 35444-44-1

On April 30, 2015, Esteve-Turrillas, Francesc A.; Mercader, Josep V.; Agullo, Consuelo; Abad-Somovilla, Antonio; Abad-Fuentes, Antonio published an article.Application of 35444-44-1 The title of the article was Moiety and linker site heterologies for highly sensitive immunoanalysis of cyprodinil in fermented alcoholic drinks. And the article contained the following:

Cyprodinil is a new-generation anilinopyrimidine fungicide widely used in crop protection and frequently found in fruits. In this study, novel derivatives of cyprodinil with linker site heterologies were synthesized and employed in order to produce antibodies with enhanced affinity. Moreover, moiety-heterologous haptens were designed and prepared for assay sensitivity improvement. Two competitive enzyme-linked immunosorbent assays for the anal. of this active substance were developed using direct and indirect formats, achieving IC50 values around 0.15 μg/L. Anal. figures of merit and usability of the optimized assays were evaluated with wine and cider as model food processed matrixes. The obtained recoveries were from 90% to 120%, and the limit of quantification was in the 1-5 μg/L range. Finally, a monitoring study (n = 150) was performed to estimate the occurrence and the concentration of cyprodinil in com. wine and cider products from different origins. We found that 28% of the analyzed wine samples contained cyprodinil residues at levels higher than 5 μg/L. The experimental process involved the reaction of Methyl 6-chloro-6-oxohexanoate(cas: 35444-44-1).Application of 35444-44-1

The Article related to cyprodinil hapten antibody wine cider elisa, Food and Feed Chemistry: Analysis and other aspects.Application of 35444-44-1

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Esteve-Turrillas, F. A.; Mercader, J. V.; Agullo, C.; Abad-Somovilla, A.; Abad-Fuentes, A. published an article in 2017, the title of the article was A class-selective immunoassay for simultaneous analysis of anilinopyrimidine fungicides using a rationally designed hapten.SDS of cas: 35444-44-1 And the article contains the following content:

The development of multianalyte immunoassays constitutes a main research issue in the field of bioanal. techniques. In the present study, class-specific antibodies against the three members of the anilinopyrimidine family of fungicides (pyrimethanil, cyprodinil and mepanipyrim) were raised by using a bioconjugate of a rationally designed hapten [5-(6-methyl-2-(phenylamino)pyrimidin-4-yl)pentanoic acid]. Highly sensitive immunoassays were developed for the generic determination of these compounds, using the competitive ELISA (ELISA). Particularly, a direct antibody-coated competitive ELISA afforded identical sensitivity for the three anilinopyrimidines, with IC50 values of 0.26, 0.27 and 0.25 μg L-1 for pyrimethanil, cyprodinil and mepanipyrim, resp. This immunoassay was fully characterized and applied to the multianalyte determination of anilinopyrimidine fungicides in white and red wines, with a limit of quantification of 1 μg L-1, average recoveries from 93.1 to 114.4%, and relative standard deviations lower than 20%. Com. wine samples were analyzed and those containing detectable anilinopyrimide residues were verified by a reference chromatog. technique. The experimental process involved the reaction of Methyl 6-chloro-6-oxohexanoate(cas: 35444-44-1).SDS of cas: 35444-44-1

The Article related to anilinopyrimidine fungicide immunoassay hapten, Food and Feed Chemistry: Analysis and other aspects.SDS of cas: 35444-44-1

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On February 12, 2014, Wang, Bin; Cancilla, John C.; Torrecilla, Jose S.; Haick, Hossam published an article.Electric Literature of 35444-44-1 The title of the article was Artificial Sensing Intelligence with Silicon Nanowires for Ultraselective Detection in the Gas Phase. And the article contained the following:

The use of molecularly modified Si nanowire field effect transistors (SiNW FETs) for selective detection in the liquid phase was successfully demonstrated. In contrast, selective detection of chem. species in the gas phase was rather limited. The application of artificial intelligence on deliberately controlled SiNW FET device parameters can provide high selectivity toward specific volatile organic compounds (VOCs). The obtained selectivity allows identifying VOCs in both single-component and multicomponent environments as well as estimating the constituent VOC concentrations The effect of the structural properties (functional group and/or chain length) of the mol. modifications on the accuracy of VOC detection is presented and discussed. The reported results have the potential to serve as a launching pad for the use of SiNW FET sensors in real-world counteracting conditions and/or applications. The experimental process involved the reaction of Methyl 6-chloro-6-oxohexanoate(cas: 35444-44-1).Electric Literature of 35444-44-1

The Article related to volatile organic sensor silicon nanowire fet artificial intelligence, Organic Analytical Chemistry: Detections and other aspects.Electric Literature of 35444-44-1

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Prasad, Bagineni; Doimo, Mara; Andreasson, Maans; L′Hote, Valentin; Chorell, Erik; Wanrooij, Sjoerd published an article in 2022, the title of the article was A complementary chemical probe approach towards customized studies of G-quadruplex DNA structures in live cells.Product Details of 35444-44-1 And the article contains the following content:

G-quadruplex (G4) DNA structures are implicated in central biol. processes and are considered promising therapeutic targets because of their links to human diseases such as cancer. However, functional details of how, when, and why G4 DNA structures form in vivo are largely missing leaving a knowledge gap that requires tailored chem. biol. studies in relevant live-cell model systems. Towards this end, we developed a synthetic platform to generate complementary chem. probes centered around one of the most effective and selective G4 stabilizing compounds, Phen-DC3. We used a structure-based design and substantial synthetic devlopments to equip Phen-DC3 with an amine in a position that does not interfere with G4 interactions. We next used this reactive handle to conjugate a BODIPY fluorophore to Phen-DC3. This generated a fluorescent derivative with retained G4 selectivity, G4 stabilization, and cellular effect that revealed the localization and function of Phen-DC3 in human cells. To increase cellular uptake, a second chem. probe with a conjugated cell-penetrating peptide was prepared using the same amine-substituted Phen-DC3 derivative The cell-penetrating peptide conjugation, while retaining G4 selectivity and stabilization, increased nuclear localization and cellular effects, showcasing the potential of this method to modulate and direct cellular uptake e.g. as delivery vehicles. The applied approach to generate multiple tailored biochem. tools based on the same core structure can thus be used to advance the studies of G4 biol. to uncover mol. details and therapeutic approaches. The experimental process involved the reaction of Methyl 6-chloro-6-oxohexanoate(cas: 35444-44-1).Product Details of 35444-44-1

The Article related to cervical cancer g quadruplex dna structure chem probe, Placeholder for records without volume info and other aspects.Product Details of 35444-44-1

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On September 30, 2021, Soraggi Battagin, Tiago; Nicolas Caccalano, Mario; Dilarri, Guilherme; Felipe Cavicchia Zamuner, Caio; Alleoni, Natalia; Leonardo Saldanha, Luiz; Bacci, Mauricio Jr.; Ferreira, Henrique published an article.Application of 35444-44-1 The title of the article was Syzygium aromaticum (clove) essential oil: An alternative for the sanitization of citrus fruit in packinghouses. And the article contained the following:

Citrus canker is a quarentenary disease caused by Xanthomonas citri subsp. citri (X. citri). Thus, sanitization of fresh fruit is a necessary measure before any com. activity. Therefore, we evaluated the clove essential oil (CEO), as an alternative sanitizer for the disinfection of citrus fruit in packinghouses. Tests in vitro and in vivo were carried out to determine the cell inhibitory concentration and to verify the efficacy of the oil for the disinfection of citrus fruits. In in vitro tests, CEO was able to inhibit X. citri when used at 0.75% (volume/volume). In experiments that simulate the sanitization process used in packinghouses, 5% CEO was as effective as the recommended sanitization product based on sodium hypochlorite. GC-MS results showed a high presence of eugenol derivatives as the major compounds of CEO. All results proved that CEO is a potential sanitizer that could be used as an alternative to sodium hypochlorite. Novelty impact statement : Exptl. evidence shows that the clove essential oil (CEO) has the same sanitization efficacy as sodium hypochlorite, which makes of CEO an alternative sanitizer for the decontamination of citrus fruits to be exported to the European Union. CEO is a safer and more sustainable sanitizer for the postharvest disinfection of citrus fruit. The experimental process involved the reaction of Methyl 6-chloro-6-oxohexanoate(cas: 35444-44-1).Application of 35444-44-1

The Article related to syzygium aromaticum essential oil citrus fruit packing sanitization, Placeholder for records without volume info and other aspects.Application of 35444-44-1

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Rosenbach, Dominic; Krimalowski, Alexander; Erabhoina, Harimohan; Thelakkat, Mukundan published an article in 2022, the title of the article was Solid polymer electrolytes from polyesters with diester sidechains for lithium metal batteries.Formula: C7H11ClO3 And the article contains the following content:

A series of polymethacrylates and polyacrylates carrying diester side chain moieties with varying alkyl spacer lengths are designed, synthesized, and evaluated as solid polymer electrolytes (SPEs) in lithium metal batteries (LMBs). These amorphous polymers with glass transition temperatures in the range of -58 to +32 °C are tested as SPEs in combination with LiTFSI or LiFSI. At an optimum salt concentration of 25 wt%, ionic conductivities up to 10-4 S cm-1 at 70 °C are achieved. These SPEs reveal high lithium transport numbers (0.5-0.7) and high electrochem. stability (5.4 V vs. Li/Li+) as determined by LSV. In combination with an ultrathin polyimide membrane and 10 wt% TiO2 nanoparticles, dendrite-free plating/stripping at 40 and 70 °C is realized in sym. Li|SPE|Li cells. Detailed extended distribution of relaxation times (eDRT) anal. of impedance measurements is employed for understanding the diverse cell processes. In solvent-free LMBs comprising a polyimide membrane soaked with the nanocomposite polyester electrolyte, lithium metal foil as the anode and an optimized LiFePO4 cathode, a very high initial specific discharge capacity of 152 mA h g- 1 (at 0.2C, 70 °C), excellent capacity retention of 94% after 100 cycles (at 1C, 70 °C) and negligible capacity fading even at 2C (96% retention after 300 cycles) are demonstrated. These novel polyester-based SPEs exhibit high cycling stability at 40 °C, making them highly attractive for room temperature applications. The experimental process involved the reaction of Methyl 6-chloro-6-oxohexanoate(cas: 35444-44-1).Formula: C7H11ClO3

The Article related to titanium oxide polyester solid polymer electrolyte lithium metal battery, Placeholder for records without volume info and other aspects.Formula: C7H11ClO3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On March 15, 2010, Tamura, Satoru; Kaneko, Masafumi; Shiomi, Atsushi; Yang, Guang-Ming; Yamaura, Toshiaki; Murakami, Nobutoshi published an article.Formula: C7H11ClO3 The title of the article was Unprecedented NES non-antagonistic inhibitor for nuclear export of Rev from Sida cordifolia. And the article contained the following:

Bioassay-guided separation from the MeOH extract of the South American medicinal plant Sida cordifolia resulted in isolation of (10E,12Z)-9-hydroxyoctadeca-10,12-dienoic acid (1) as an unprecedented NES non-antagonistic inhibitor for nuclear export of Rev. This mechanism of action was established by competitive experiment by the biotinylated probe derived from leptomycin B, the known NES antagonistic inhibitor. Addnl., structure-activity relationship anal. by use of the synthesized analogs clarified cooperation of several functionalities in the Rev-export inhibitory activity of 1. The experimental process involved the reaction of Methyl 6-chloro-6-oxohexanoate(cas: 35444-44-1).Formula: C7H11ClO3

The Article related to sida hydroxyoctadecadienoate inhibitor nuclear export rev protein, Plant Biochemistry: Composition and Products and other aspects.Formula: C7H11ClO3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On September 6, 2017, Zhao, Wei; Wurz, Ryan P.; Peters, Jonas C.; Fu, Gregory C. published an article.Safety of Methyl 6-chloro-6-oxohexanoate The title of the article was Photoinduced, Copper-Catalyzed Decarboxylative C-N Coupling to Generate Protected Amines: An Alternative to the Curtius Rearrangement. And the article contained the following:

The Curtius rearrangement is a classic, powerful method for converting carboxylic acids into protected amines, but its widespread use is impeded by safety issues (the need to handle azides). We have developed an alternative to the Curtius rearrangement that employs a copper catalyst in combination with blue-LED irradiation to achieve the decarboxylative coupling of aliphatic carboxylic acid derivatives (specifically, readily available N-hydroxyphthalimide esters) to afford protected amines under mild conditions. This C-N bond-forming process is compatible with a wide array of functional groups, including an alc., aldehyde, epoxide, indole, nitroalkane, and sulfide. Control reactions and mechanistic studies are consistent with the hypothesis that copper species are engaged in both the photochem. and the key bond-forming step, which occurs through out-of-cage coupling of an alkyl radical. The experimental process involved the reaction of Methyl 6-chloro-6-oxohexanoate(cas: 35444-44-1).Safety of Methyl 6-chloro-6-oxohexanoate

The Article related to photoinduced copper catalyzed decarboxylative c n coupling, protected amine preparation, General Organic Chemistry: Synthetic Methods and other aspects.Safety of Methyl 6-chloro-6-oxohexanoate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On September 23, 2015, Le, Chi “Chip”; MacMillan, David W. C. published an article.Recommanded Product: Methyl 6-chloro-6-oxohexanoate The title of the article was Fragment Couplings via CO2 Extrusion-Recombination: Expansion of a Classic Bond-Forming Strategy via Metallaphotoredox. And the article contained the following:

In this study we demonstrate that mol. fragments, which can be readily coupled via a simple, in situ RO-C=OR bond-forming reaction, can subsequently undergo metal insertion-decarboxylation-recombination to generate Csp2-Csp3 bonds when subjected to metallaphotoredox catalysis. In this embodiment the conversion of a wide variety of mixed anhydrides (formed in situ from carboxylic acids and acyl chlorides) to fragment-coupled ketones is accomplished in good to high yield. A three-step synthesis of the medicinal agent edivoxetine is also described using this new decarboxylation-recombination protocol. The experimental process involved the reaction of Methyl 6-chloro-6-oxohexanoate(cas: 35444-44-1).Recommanded Product: Methyl 6-chloro-6-oxohexanoate

The Article related to ketone preparation, carboxylic acid acyl chloride coupling iridium nickel catalyst, General Organic Chemistry: Synthetic Methods and other aspects.Recommanded Product: Methyl 6-chloro-6-oxohexanoate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On January 3, 2017, Cheung, Chi Wai; Ploeger, Marten Leendert; Hu, Xile published an article.COA of Formula: C7H11ClO3 The title of the article was Direct amidation of esters with nitroarenes. And the article contained the following:

Herein, nickel-catalyzed reductive coupling of unactivated esters with nitroarenes to furnish in one step a wide range of amides bearing functional groups relevant to the development of drugs and agrochems. has been reported. The method has been used to expedite the syntheses of bio-active mols. and natural products, as well as their post-synthetic modifications. Preliminary mechanistic study indicates a reaction pathway distinct from conventional amidation methods using anilines as nitrogen sources. The experimental process involved the reaction of Methyl 6-chloro-6-oxohexanoate(cas: 35444-44-1).COA of Formula: C7H11ClO3

The Article related to amide preparation, ester nitroarene reductive amidation, General Organic Chemistry: Synthetic Methods and other aspects.COA of Formula: C7H11ClO3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics