Sanchez, Laura M. et al. published their research in Organic Letters in 2011 | CAS: 36157-41-2

2,5-Dichlorothiophene-3-carboxylic acid (cas: 36157-41-2) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Product Details of 36157-41-2

Versatile Method for the Detection of Covalently Bound Substrates on Solid Supports by DART Mass Spectrometry was written by Sanchez, Laura M.;Curtis, Matthew E.;Bracamonte, Bianca E.;Kurita, Kenji L.;Navarro, Gabriel;Sparkman, O. David;Linington, Roger G.. And the article was included in Organic Letters in 2011.Product Details of 36157-41-2 This article mentions the following:

Anal. of substrates directly on solid phase resins without the need for sep. cleavage conditions remains an outstanding challenge in the field of solid phase synthesis. The authors now present the 1st example of simultaneous cleavage and mass spectrometric anal. of peptides from solid supports using direct anal. in real time (DART) mass spectrometry. This method is compatible with a diverse array of solid phase resins and is suitable for anal. of both peptides and organic substrates. In the experiment, the researchers used many compounds, for example, 2,5-Dichlorothiophene-3-carboxylic acid (cas: 36157-41-2Product Details of 36157-41-2).

2,5-Dichlorothiophene-3-carboxylic acid (cas: 36157-41-2) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Product Details of 36157-41-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Boyd, Robert E. et al. published their research in Journal of Medicinal Chemistry in 2001 | CAS: 36157-41-2

2,5-Dichlorothiophene-3-carboxylic acid (cas: 36157-41-2) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.COA of Formula: C5H2Cl2O2S

2 Adrenoceptor Agonists as Potential Analgesic Agents. 3. Imidazolylmethylthiophenes was written by Boyd, Robert E.;Rasmussen, C. Royce;Press, Jeffery B.;Raffa, Robert B.;Codd, Ellen E.;Connelly, Charlene D.;Li, Quan S.;Martinez, Rebecca P.;Lewis, Martin A.;Almond, Harold R.;Reitz, Allen B.. And the article was included in Journal of Medicinal Chemistry in 2001.COA of Formula: C5H2Cl2O2S This article mentions the following:

A series of imidazolylmethylthiophenes has been prepared and evaluated as ligands for the 伪2 adrenoceptor. These compounds were tested in two animal models that are predictive of analgesic activity in humans. The 3-thienyl compounds were generally the most potent, particularly those with substitution in the 4-position. A subset of the most active compounds was further evaluated for adverse cardiovascular effects in the anesthetized rat model. In addition to excellent binding at the 伪2D adrenoceptor, the 4-bromo analogs I [R = H, Me] were very active in the rat abdominal irritant test (RAIT) with ED50 doses of 0.38 and 0.31 mg/kg, resp. A pharmacophore model based on the biol. activity of the present series, dexmedetomidine and its conformationally restrained analogs was constructed. In the experiment, the researchers used many compounds, for example, 2,5-Dichlorothiophene-3-carboxylic acid (cas: 36157-41-2COA of Formula: C5H2Cl2O2S).

2,5-Dichlorothiophene-3-carboxylic acid (cas: 36157-41-2) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.COA of Formula: C5H2Cl2O2S

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Jennifer, Samson Jegan et al. published their research in Journal of Molecular Structure in 2022 | CAS: 36157-41-2

2,5-Dichlorothiophene-3-carboxylic acid (cas: 36157-41-2) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.SDS of cas: 36157-41-2

Role of Cl• • •Cl halogen bonds in tuning the crystals of Uranyl-Dicholorothiophene carboxylate based hybrid cluster materials through N-donor counter ions was written by Jennifer, Samson Jegan;Razak, Ibrahim Abdul;Ebenezer, Cheriyan;Solomon, Rajadurai Vijay. And the article was included in Journal of Molecular Structure in 2022.SDS of cas: 36157-41-2 This article mentions the following:

Hydrothermal synthesis has afforded eight uranyl bearing hybrid materials with various ancillary ligands such as 2,5-Dichlorothiophene-3-carboxylate (CTDC) as the main ligand and 4,4′-bipyridine (4BPY), 4,4′-Trimethylenedipyridine (4TBY), trans-1-(2-pyridyl)-2-(4-pyridyl)ethylene (TTPY), 1,10-Phenanthroline (PHEN), or 2,2′-Dipyridylamine (2DPY). These uranyl complexes; (UO2) 0.5 (CTDC)(4BPY)0.5 (I), UO2(CTDC)2(4BPY)0.5, (II); [(UO2)43-O)22-OH)2(CTDC)4(4TBY)2].(H24TBY).2H2O (III); [(UO2)2(μ3-O)(CTDC)3].(HTTPY).H2O (IV); [(UO2)(CTDC)2(PHEN)]2 (V); [(UO2)(μ2-OH)(CTDC)(PHEN)] (VI); [UO2(CTDC)3]2 (H2DPY)2 (VII); [UO2(CTDC)3]2 (H4TBY)2 (VIII) were characterized by single-crystal X-ray diffraction, powder X-ray diffraction, elemental anal., FT-IR spectroscopy, thermogravimetric anal. and by their uranyl emission spectra. The complexes (I) and (II) are the first examples of uranyl complexes with aromatic carboxylates formed in the presence of a coordinated 4,4′-bipyridine ligand. Here, the complexes (V) and (VI) were concomitant polymorphs while (II) and (VIII) are polymorphs of (I) and (III) resp. and were obtained by varying the pH in synthetic procedures. Halogen bonding (Cl···Cl) interactions were found to play a strong role in expanding their dimensionality into 3D and defining their crystal packing patterns. To gain insights into the Cl···Cl interactions, a detailed QTAIM study is taken up. The photocatalytic properties of (I-VIII) for degradation of various organic dyes under Hg-lamp irradiation were performed. Interestingly, complexes (I, II, V) which are mononuclear uranyl clusters possess the highest efficiency in degradation of organic dyes than the tetranuclear uranyl clusters (III, IV). Thus, this work sheds light on the structural features of these uranyl complexes to extend our knowledge and understanding of uranyl chem. In the experiment, the researchers used many compounds, for example, 2,5-Dichlorothiophene-3-carboxylic acid (cas: 36157-41-2SDS of cas: 36157-41-2).

2,5-Dichlorothiophene-3-carboxylic acid (cas: 36157-41-2) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.SDS of cas: 36157-41-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics