Category: 38939-88-7

On October 10, 2013, Ono, Yohei; Shiren, Kazushi; Kageyama, Akiko published a patent.Product Details of 38939-88-7 The title of the patent was Benzofluorenes bearing diarylamino and 9-carbazolyl groups, materials containing them for emitter layers of organic electroluminescent devices, and displays and lighting systems. And the patent contained the following:

The title benzofluorenes are represented by I [R = C1-6 alkyl, C3-6 cycloalkyl, (C1-4 alkyl-substituted) C6-24 aryl, (C1-4 alkyl-substituted) C5-24 heteroaryl; one of A and B = (substituted) 9-carbazolyl, the other of A and B = diarylamino]. The title organic electroluminescent devies, preferably, blue-emitting, show high color saturation and long service life. Preferable substances for electron-transporting layers and/or electron-injecting layers of the devices are also disclosed. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Product Details of 38939-88-7

The Article related to carbazolyl diarylamino benzofluorene organic electroluminescent device, electroluminescent display carbazolyl diarylamino benzofluorene, lighting system electroluminescent carbazolyl diarylamino benzofluorene and other aspects.Product Details of 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On March 28, 2013, Ono, Yohei; Shiren, Kazushi; Kageyama, Akiko published a patent.Category: chlorides-buliding-blocks The title of the patent was Benzofluorenes bearing diarylamino and 9-carbazolyl groups, materials containing them for emitter layers of organic electroluminescent devices, and displays and lighting systems. And the patent contained the following:

The title benzofluorenes are represented by I [R = C1-6 alkyl, C3-6 cycloalkyl, (C1-4 alkyl-substituted) C6-24 aryl, (C1-4 alkyl-substituted) C5-24 heteroaryl; one of A and B = (substituted) 9-carbazolyl, the other of A and B = diarylamino]. The title organic electroluminescent devies, preferably, blue-emitting, show high color saturation and long service life. Preferable substances for electron-transporting layers and/or electron-injecting layers of the devices are also disclosed. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Category: chlorides-buliding-blocks

The Article related to carbazolyl diarylamino benzofluorene organic electroluminescent device, electroluminescent display carbazolyl diarylamino benzofluorene, lighting system electroluminescent carbazolyl diarylamino benzofluorene and other aspects.Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On August 1, 2010, Sun, Ranfeng; Li, Yongqiang; Lue, Maoyun; Xiong, Lixia; Wang, Qingmin published an article.Related Products of 38939-88-7 The title of the article was Synthesis, larvicidal activity, and SAR studies of new benzoylphenylureas containing oxime ether and oxime ester group. And the article contained the following:

A series of new structural benzoylphenylureas (BPUs) containing oxime ether and oxime ester groups, e.g. I [R = i-Pr, PhCH2, R1 = Me; R = C(O)Me, C(O)Ph, R1 = H] were designed and synthesized. The larvicidal activities of these benzoylphenylureas against Oriental armyworm and mosquito were evaluated and the results of the bioassay displayed a specific structure-activity relationship (SAR). Most of the compounds exhibited excellent larvicidal activities against Oriental armyworm and mosquito. Interestingly, some compounds showed a different structure-activity relationship towards diamondback moth, beet armyworm, and corn borer even though the three tested insects all belong to the same insect order. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Related Products of 38939-88-7

The Article related to benzoylphenylurea oxime ether ester preparation larvicidal activity sar, larvicidal benzoylphenylurea sar oriental armyworm mosquito, sar benzoylphenylurea toxicity diamondback moth beet armyworm corn borer and other aspects.Related Products of 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On November 13, 2003, Heppner, Philip D.; Charles, Leslie J.; Dellaria, Joseph F.; Merrill, Bryon A.; Mickelson, John W. published a patent.Recommanded Product: 2-Chloro-4-methyl-1-nitrobenzene The title of the patent was Preparation of aryl ether substituted imidazoquinolines as immune response modifiers. And the patent contained the following:

The title compounds [I; X = (CH2)2, CHEtCH2, etc.; R1 = alkenyl, aryl, R4-aryl; R2 = H, alkyl, alkenyl, etc.; R4 = alkyl, alkenyl which may be interrupted by one or more O atoms; R3 = H, alkyl; n = 0-4; R = alkyl, alkoxy, OH, etc.] that contain ether and aryl or alkenyl functionality at the 1-position, and are useful as immune response modifiers, were prepared E.g., a multi-step synthesis of I [X = (CH2)2; R1 = CH2CCH; R2 = H; n = 0] which showed the lowest effective concentration of 0.12 μM and 1.11 μM to induce biosynthesis of interferon α and TNFα in human cells, resp., was given. The compounds I can induce the biosynthesis of various cytokines and are useful in the treatment of a variety of conditions including viral diseases and neoplastic diseases. The pharmaceutical composition comprising the compound I is claimed. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Recommanded Product: 2-Chloro-4-methyl-1-nitrobenzene

The Article related to imidazoquinoline aryl ether preparation immunomodulator antiviral antitumor, cytokine interferon tnf alpha biosynthesis inducer imidazoquinoline preparation, tumor necrosis factor alpha biosynthesis inducer imidazoquinoline preparation and other aspects.Recommanded Product: 2-Chloro-4-methyl-1-nitrobenzene

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On March 3, 2016, Baum, Erich W.; Fischer, Lindsey G.; Crouse, Gary D.; Sparks, Thomas C. published a patent.SDS of cas: 38939-88-7 The title of the patent was Preparation of 5-(1,2,4-triazol-3-yl)indan-2-ylurea and 6-(1,2,4-triazol-3-yl)-1,2,3,4-tetrahydronaphthalen-2-ylurea derivatives as pesticides, and intermediates, compositions, and processes related thereto. And the patent contained the following:

This disclosure relates to the field of mols. having pesticidal utility against pests such as Phylum nematoda, Arthropoda, and/or Mohusca, processes to produce such mols. and intermediates used in such processes, compositions containing such mols., and processes of using such mols. against such pests. More specifically the title compounds I [R1, R2, R3, R4, R5, R6, R7, R9 = independently H, F, Cl, Br, iodo, cyano, NO2, OH, or each (un)substituted C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, C1-4 haloalkyl, C1-4 alkoxy, C1-4 haloalkoxy, C3-6cycloalkyl, or C3-6cycloalkoxy; R8 = H; L = (un)substituted C1-4 alkyl; R10 = H or each (un)substituted C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, C1-4 haloalkyl, (C1-4 alkyl)(C3-6 cycloalkyl), C1-4 alkylphenyl, C1-4 alkylheterocyclyl, (C1-4 alkyl)O(C1-4 alkyl), (C1-4 alkyl)OC(O)(C1-4 alkyl), (C1-4 alkyl)OC(O)O(C1-4 alkyl), C(O)(C1-4 alkyl), or C(O)phenyl, wherein each alkyl, alkenyl, alkynyl, haloalkyl, cycloalkyl; R11, R12, R13, R14, R15 = each independently H, F, Cl, Br, iodo, cyano, NO2, OH, C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, C1-4 haloalkyl, C1-4 alkoxy, C1-4 haloalkoxy, C3-6 cycloalkyl, or C3-6 cycloalkoxy; R16, R17 = independently group (G), H, or each (un)substituted C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, C1-4 haloalkyl, (C1-4 alkyl)(C3-6 cycloalkyl), C1-4 alkylphenyl, C1-4 alkylheterocyclyl, (C1-4 alkyl)C(O)(C1-4 alkyl), or (C1-4 alkyl)C(O)O(C1-4 alkyl); group (G) = (un)substituted 4 to 8 membered heterocyclyl ring formed by taking R16 and R17 together with (S)-Cx(Nx)] are prepared The compounds I may be used, for example, as nematicides, acaricides, insecticides, miticides, and/or molluscicides. Thus, dichloromethane (4 mL), water (2 mL), and sodium bicarbonate (0.271 g, 3.22 mmol) were added 5-[1-[4-(trifluoromethoxy)phenyl]-1H-1,2,4-triazol-3-yl]-2,3-dihydro-1H-inden-2-amine dihydrochloride (0.279 g, 0.645 mmol) in a vial (25 mL) equipped with a stir bar under nitrogen. The resulting mixture was cooled in an ice water bath, followed by adding triphosgene (0.0770 g, 0.258 mmol) in one portion and the resulting reaction was stirred vigorously until the conversion of the starting material was observed After workup, the solid obtained was suspended in acetonitrile (6 mL) in a round-bottomed flask (100 mL) equipped with a stir bar under nitrogen, treated with cesium carbonate (0.231 g, 0.709 mmol) and 1-(2-isopropyl-5-methylphenyl)thiourea (0.134 g, 0.645 mmol), and stirred overnight at room temperature to give, after workup and flash chromatog., 39% 1-[(2-isopropyl-5-methylphenyl)carbamothioyl]-3-[5-[1-[4-(trifluoromethoxy)phenyl]-1,2,4-triazol-3-yl]indan-2-yl]urea (II). II controlled 50-100% beet armyworm (Spodoptera exigua) and cabbage looper (Thchoplusia ni) and 80-100% yellow fever mosquito (Aedes aegypti) eggs. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).SDS of cas: 38939-88-7

The Article related to triazolylindanylurea triazolyltetrahydronaphthalenylurea preparation pesticide, nematicide acaricide insecticide triazolylindanylurea triazolyltetrahydronaphthalenylurea preparation, miticides molluscicide triazolylindanylurea triazolyltetrahydronaphthalenylurea preparation and other aspects.SDS of cas: 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On March 3, 2016, Baum, Erich W.; Fischer, Lindsey G.; Crouse, Gary D.; Sparks, Thomas C. published a patent.SDS of cas: 38939-88-7 The title of the patent was Preparation of 5-(1,2,4-triazol-3-yl)indan-2-ylurea and 6-(1,2,4-triazol-3-yl)-1,2,3,4-tetrahydronaphthalen-2-ylurea derivatives as pesticides, and intermediates, compositions, and processes related thereto. And the patent contained the following:

This disclosure relates to the field of mols. having pesticidal utility against pests such as Phylum nematoda, Arthropoda, and/or Mohusca, processes to produce such mols. and intermediates used in such processes, compositions containing such mols., and processes of using such mols. against such pests. More specifically the title compounds I [R1, R2, R3, R4, R5, R6, R7, R9 = independently H, F, Cl, Br, iodo, cyano, NO2, OH, or each (un)substituted C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, C1-4 haloalkyl, C1-4 alkoxy, C1-4 haloalkoxy, C3-6cycloalkyl, or C3-6cycloalkoxy; R8 = H; L = (un)substituted C1-4 alkyl; R10 = H or each (un)substituted C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, C1-4 haloalkyl, (C1-4 alkyl)(C3-6 cycloalkyl), C1-4 alkylphenyl, C1-4 alkylheterocyclyl, (C1-4 alkyl)O(C1-4 alkyl), (C1-4 alkyl)OC(O)(C1-4 alkyl), (C1-4 alkyl)OC(O)O(C1-4 alkyl), C(O)(C1-4 alkyl), or C(O)phenyl, wherein each alkyl, alkenyl, alkynyl, haloalkyl, cycloalkyl; R11, R12, R13, R14, R15 = each independently H, F, Cl, Br, iodo, cyano, NO2, OH, C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, C1-4 haloalkyl, C1-4 alkoxy, C1-4 haloalkoxy, C3-6 cycloalkyl, or C3-6 cycloalkoxy; R16, R17 = independently group (G), H, or each (un)substituted C1-4 alkyl, C2-4 alkenyl, C2-4 alkynyl, C1-4 haloalkyl, (C1-4 alkyl)(C3-6 cycloalkyl), C1-4 alkylphenyl, C1-4 alkylheterocyclyl, (C1-4 alkyl)C(O)(C1-4 alkyl), or (C1-4 alkyl)C(O)O(C1-4 alkyl); group (G) = (un)substituted 4 to 8 membered heterocyclyl ring formed by taking R16 and R17 together with (S)-Cx(Nx)] are prepared The compounds I may be used, for example, as nematicides, acaricides, insecticides, miticides, and/or molluscicides. Thus, dichloromethane (4 mL), water (2 mL), and sodium bicarbonate (0.271 g, 3.22 mmol) were added 5-[1-[4-(trifluoromethoxy)phenyl]-1H-1,2,4-triazol-3-yl]-2,3-dihydro-1H-inden-2-amine dihydrochloride (0.279 g, 0.645 mmol) in a vial (25 mL) equipped with a stir bar under nitrogen. The resulting mixture was cooled in an ice water bath, followed by adding triphosgene (0.0770 g, 0.258 mmol) in one portion and the resulting reaction was stirred vigorously until the conversion of the starting material was observed After workup, the solid obtained was suspended in acetonitrile (6 mL) in a round-bottomed flask (100 mL) equipped with a stir bar under nitrogen, treated with cesium carbonate (0.231 g, 0.709 mmol) and 1-(2-isopropyl-5-methylphenyl)thiourea (0.134 g, 0.645 mmol), and stirred overnight at room temperature to give, after workup and flash chromatog., 39% 1-[(2-isopropyl-5-methylphenyl)carbamothioyl]-3-[5-[1-[4-(trifluoromethoxy)phenyl]-1,2,4-triazol-3-yl]indan-2-yl]urea (II). II controlled 50-100% beet armyworm (Spodoptera exigua) and cabbage looper (Thchoplusia ni) and 80-100% yellow fever mosquito (Aedes aegypti) eggs. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).SDS of cas: 38939-88-7

The Article related to triazolylindanylurea triazolyltetrahydronaphthalenylurea preparation pesticide, nematicide acaricide insecticide triazolylindanylurea triazolyltetrahydronaphthalenylurea preparation, miticides molluscicide triazolylindanylurea triazolyltetrahydronaphthalenylurea preparation and other aspects.SDS of cas: 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On October 29, 1992, Shibayama, Katsuhiro; Makino, Tetsuya; Imaoka, Takayuki; Katou, Tetsuya; Kaneko, Masayuki published a patent.Formula: C7H6ClNO2 The title of the patent was Preparation of tricyclic triazole derivatives as antiinflammatory, antiallergic, and anti-platelet activating factor (PAF) drugs. And the patent contained the following:

The title compounds [I; R1 = H, alkyl, C3-5 cycloalkyl; R2, R3 = H, alkyl, alkoxy, halo; W = CO, CR4R5; R4, R5 = H, alkyl; A = C1-5 linear or branched (un)saturated alkylene optionally containing heteroatoms; l = 0-2; n = 1-3; Y = N, C; Z = C(B)Ar1Ar2, CAr1Ar2, OCHAr1Ar2, fused aromatic ring; B = H, HO, MeO; Ar1, Ar2 = H, (un)substituted aryl] are prepared Thus, cyclocondensation of 4-(3-ethoxypropyl)-2-chloroquinoxaline (preparation given) with acetohydrazide in BuOH under reflux and bromination of the the resulting [1,2,4]triazolo[4,3-a]quinoxaline derivative (II; R6 = OEt) with 48% HBr followed by condensation with 4-(diphenylmethylene)piperidine and NaCO3 in DMF at 60-70° gave a title compound (II; R6 = Q). I at 50 mg/kg p.o. inhibited 44-75% passive cutaneous anaphylaxis and 19-87% histamine-induced allergy in rats. I showed IC50 of 0.013-5.4 μg/mL for inhibiting PAF-induced rabbit’s blood platelet aggregation. A tablet formulation containing II (R6 = Q1) was given. A total of 121 I were prepared The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Formula: C7H6ClNO2

The Article related to tricyclic triazole preparation antiinflammatory, antiallergic triazoloquinoxaline triazolobenzodiazepine, platelet activating factor antagonist triazoloquinoxaline, paf antagonist triazoloquinoxaline, blood platelet aggregation inhibitor triazoloquinoxaline, triazolobenzimidazole antiinflammatory and other aspects.Formula: C7H6ClNO2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On March 25, 2010, Kajino, Masahiro; Imaeda, Toshihiro; Ono, Koji; Aso, Kazuyoshi; Tarui, Naoki published a patent.Synthetic Route of 38939-88-7 The title of the patent was Preparation of 2-aminobenzimidazole derivatives as gastric acid secretion inhibitors. And the patent contained the following:

There are disclosed acid secretion inhibitors containing compounds represented by formula [I; R1’s may be the same or different and each represents a hydrogen atom, a halogen atom, an optionally substituted hydrocarbon group, an optionally substituted heterocyclic group, an optionally substituted alkoxy group, a hydroxy group or an optionally substituted amino group; R2 represents a hydrogen atom or a substituent; R3 represents a hydrogen atom or a substituent; ring A represents an optionally substituted carbon ring or an optionally substituted heterocyclic ring; and n represents an integer of 1-4], salts thereof, or prodrugs of the compounds or salts. These compounds inhibit proton,potassium-ATPase (H+/K+-ATPase) and are useful as gastric acid secretion inhibitors. There is also provided the preventive or therapeutic method for peptic ulcer, Zollinger-Ellison syndrome, gastritis, gastroesophageal reflux disease (GERD), symptomatic gastroesophageal reflux disease (symptomatic GERD), Barrett esophagus, functional dyspepsia, gastric cancer (stomach cancer), gastric MALT lymphoma, ulcer caused by nonsteroidal antiinflammatory agents, ulcer or hyper-gastric acidity (excessive acid secretion) caused by postsurgical stress, acute stress ulcer, hemorrhagic gastritis, stress, or upper digestive tract hemorrhage by administering the compound in mammals. Thus, a solution of 666 mg benzene-1,2-diamine in 30 mL THF was treated with 1.08 g 2-isothiocyanato-1,3,5-trimethyl benzene, refluxed for 4 h, treated with 2.24 g 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride, and refluxed for 50 min to give, after workup and recrystallization from EtOAc/hexane, 253 mg N-(2,4,6-trimethylphenyl)-1H-benzimidazol-2-amine (II). II N-(4-fluoro-2,6-dimethylphenyl)-5-methoxy-4-methyl-1H-benzimidazol-2-amine (III) showed IC50 of 970 and 14 nM, resp., against H+/K+-ATPase. A tablet formulation containing I was described. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Synthetic Route of 38939-88-7

The Article related to aminobenzimidazole preparation gastric acid secretion inhibitor, proton potassium atpase inhibitor aminobenzimidazole preparation, peptic ulcer zollinger ellison syndrome prevention treatment aminobenzimidazole preparation, gastritis gastroesophageal reflux disease gerd prevention treatment aminobenzimidazole preparation and other aspects.Synthetic Route of 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On September 29, 1993, Axelsson, Oskar; Peters, Dan; Nielsen, Elsebet Ostergaard; Christophersen, Palle published a patent.Electric Literature of 38939-88-7 The title of the patent was Imidazole compounds, their preparation and use. And the patent contained the following:

The title compounds, particularly the benzimidazole derivatives and 3H-imidazo[4,5-b]pyridine derivatives, I (X, Y = carbon, nitrogen; R12, R13 = alkyl; R4-R7 = H, halo, amino, cyano, etc.) and their uses for the treatment of diseases responsive to blocking of calcium channels of the central nervous system are claimed. Such diseases include degenerative changes associated with stroke, ischemia, migraine, psychosis, Parkinson’s disease, depression, epilepsy, or convulsive disorders. For example, 1-(4-iodophenyl)-4-fluorobenzimidazole (II) had an in vitro activity as L-type calcium channel blocker. Other I were tested for activity as N-type and P-type calcium channel blockers. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Electric Literature of 38939-88-7

The Article related to ischemia benzimidazole imidaopyridine phenyl, migraine benzimidazole imidaopyridine phenyl, antipsychotic benzimidazole imidaopyridine phenyl, antidepressant benzimidazole imidaopyridine phenyl, antiepileptic benzimidazole imidaopyridine phenyl, anticonvulsant benzimidazole imidaopyridine phenyl, calcium channel blocker benzimidazole imidaopyridine and other aspects.Electric Literature of 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On September 29, 1993, Axelsson, Oskar; Peters, Dan; Nielsen, Elsebet Ostergaard; Christophersen, Palle published a patent.Electric Literature of 38939-88-7 The title of the patent was Imidazole compounds, their preparation and use. And the patent contained the following:

The title compounds, particularly the benzimidazole derivatives and 3H-imidazo[4,5-b]pyridine derivatives, I (X, Y = carbon, nitrogen; R12, R13 = alkyl; R4-R7 = H, halo, amino, cyano, etc.) and their uses for the treatment of diseases responsive to blocking of calcium channels of the central nervous system are claimed. Such diseases include degenerative changes associated with stroke, ischemia, migraine, psychosis, Parkinson’s disease, depression, epilepsy, or convulsive disorders. For example, 1-(4-iodophenyl)-4-fluorobenzimidazole (II) had an in vitro activity as L-type calcium channel blocker. Other I were tested for activity as N-type and P-type calcium channel blockers. The experimental process involved the reaction of 2-Chloro-4-methyl-1-nitrobenzene(cas: 38939-88-7).Electric Literature of 38939-88-7

The Article related to ischemia benzimidazole imidaopyridine phenyl, migraine benzimidazole imidaopyridine phenyl, antipsychotic benzimidazole imidaopyridine phenyl, antidepressant benzimidazole imidaopyridine phenyl, antiepileptic benzimidazole imidaopyridine phenyl, anticonvulsant benzimidazole imidaopyridine phenyl, calcium channel blocker benzimidazole imidaopyridine and other aspects.Electric Literature of 38939-88-7

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics