Category: 39637-74-6

SDS of cas: 39637-74-6《Direct Transformation of Arylamines to Aryl Halides via Sodium Nitrite and N-Halosuccinimide》 was published in 2018. The authors were Mukhopadhyay, Sushobhan;Batra, Sanjay, and the article was included in《Chemistry – A European Journal》. The author mentioned the following in the article:

A one-pot universal approach for transforming arylamines to aryl halides via reaction with sodium nitrite (NaNO₂) and N-halosuccinimides (NXS) in DMF at room temperature under metal- and acid-free condition was described. This new protocol that is complementary to the Sandmeyer reaction, is suggested to involve the in situ generation of nitryl halide induce nitrosylation of aryl amine to form the diazo intermediate which is halogenated to furnish the aryl halide. And (1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) (cas: 39637-74-6) was used in the research process.

(1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) (cas: 39637-74-6 SDS of cas: 39637-74-6) is used as a resolving agent for alcohols as the diastereomeric esters by crystallization or chromatography and as a chiral derivatization reagent for determination of enantiomeric excess of alcohols and amines.

Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Electric Literature of C10H13ClO3《Silver-Catalyzed Dibromotrifluoromethoxylation of Terminal Alkynes》 was published in 2021. The authors were Wang, Feng;Guo, Yuecong;Zhang, Yutong;Tang, Pingping, and the article was included in《ACS Catalysis》. The author mentioned the following in the article:

A silver-catalyzed dibromotrifluoromethoxylation of terminal alkynes has been reported, which provides the corresponding 1,1-dibromo-2-(trifluoromethoxy)alkenes in good yields and high regioselectivity under mild reaction conditions. The reaction exhibits a broad substrate scope and applies to late-stage trifluoromethoxylation of complex small mols. Moreover, the products can be further modified, which provides a convenient method for the synthesis of compounds containing the OCF₃ group. And (1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) (cas: 39637-74-6) was used in the research process.

(1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) (cas: 39637-74-6 Electric Literature of C10H13ClO3) is a chiral derivatizing agent. It can be prepared by reacting (-)-(1S,4R)-camphanic acid with thionyl chloride.

Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Electric Literature of C10H13ClO3《Highly Efficient Kinetic Resolution of Aryl-Alkenyl Alcohols by Ru-Catalyzed Hydrogen Transfer》 was published in 2021. The authors were You, Yipeng;Jin, Ming Yu;Tao, Guanyu;Xing, Xiangyou, and the article was included in《Molecules》. The author mentioned the following in the article:

By exploiting the recently developed Ru-catalysts of minimal stereogenicity, herein a highly efficient kinetic resolution of aryl-alkenyl alcs. through hydrogen transfer weas reported. This method enabled such versatile chiral building blocks for organic synthesis as allylic alcs., to be readily accessed with excellent enantiomeric excesses at practically useful conversions. The experimental procedure involved many compounds, such as (1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) (cas: 39637-74-6) .

(1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) (cas: 39637-74-6 Electric Literature of C10H13ClO3) is a chiral derivatizing agent. It can be prepared by reacting (-)-(1S,4R)-camphanic acid with thionyl chloride.

Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Related Products of 39637-74-6In 2019, Medena, Caleb;Calogero, Francesco;Lemoine, Quentin;Aubert, Corinne;Derat, Etienne;Fensterbank, Louis;Gontard, Geoffrey;Khaled, Omar;Vanthuyne, Nicolas;Moussa, Jamal;Ollivier, Cyril;Petit, Marc;Barbazanges, Marion published 《A HELIXOL-Derived Bisphosphinite Ligand: Synthesis and Application in Gold-Catalyzed Enynes Cycloisomerization》. 《European Journal of Organic Chemistry》published the findings. The article contains the following contents:

The synthesis, optical resolution through derivatization, characterization, and utilization of a new helical bis(phosphinite gold)complex derived from 2,15-bishydroxy[6]helicene (HELIXOL) are described. By using an efficient cobalt catalyst, neither irradiation nor high catalytic loading was required to access the helicene of interest. The latter was phosphorylated to afford a new chiral ligand that was studied. Especially, treatment with AuCl(SMe₂) gives a dinuclear gold complex that was used in cycloisomerization reactions. The experimental procedure involved many compounds, such as (1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) (cas: 39637-74-6) .

(1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) (cas: 39637-74-6 Related Products of 39637-74-6) is used as a resolving agent for alcohols as the diastereomeric esters by crystallization or chromatography and as a chiral derivatization reagent for determination of enantiomeric excess of alcohols and amines.

Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Zhang, Kun;Rombach, David;Notel, Nicolas Yannick;Jeschke, Gunnar;Katayev, Dmitry published 《Radical Trifluoroacetylation of Alkenes Triggered by a Visible-Light-Promoted C-O Bond Fragmentation of Trifluoroacetic Anhydride》 in 2021. The article was appeared in 《Angewandte Chemie, International Edition》. They have made some progress in their research.Formula: C10H13ClO3 The article mentions the following:

A mild and operationally simple trifluoroacylation strategy of olefines was reported, that utilized trifluoroacetic anhydride as a low-cost and readily available reagent. This light-mediated process was fundamentally different from conventional methodologies and occurs through a trifluoroacyl radical mechanism promoted by a photocatalyst, which triggers a C-O bond fragmentation. Mechanistic studies (kinetic isotope effects, spectroelectrochem., optical spectroscopy, theor. investigations) highlighted the evidence of a fleeting CF₃CO radical under photoredox conditions. The trifluoroacyl radical could be stabilized under CO atm., delivering the trifluoroacetylation product with higher chem. efficiency. Furthermore, the method could be turned into a trifluoromethylation protocol by simply changing the reaction parameters. Beyond simple alkenes, this method allows for chemo- and regioselective functionalization of small-mol. drugs and common pharmacophores. And (1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) (cas: 39637-74-6) was used in the research process.

(1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) (cas: 39637-74-6 Formula: C10H13ClO3) is a chiral derivatizing agent. It can be prepared by reacting (-)-(1S,4R)-camphanic acid with thionyl chloride.

Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Yeung, Chi-Tung;Chan, Wesley Ting Kwok;Lo, Wai-Sum;Law, Ga-Lai;Wong, Wing-Tak published 《Synthesis of a conformationally stable atropisomeric pair of biphenyl scaffold containing additional stereogenic centers》 in 2019. The article was appeared in 《Molecules》. They have made some progress in their research.Synthetic Route of C10H13ClO3 The article mentions the following:

The synthesis of a new CF₃-containing stereogenic atropisomeric pair of ortho-disubstituted biphenyl scaffolds I and II is presented. The atropisomers are surprisingly conformationally stable for isolation. X-ray structures show that their stability comes from an intramol. hydrogen bond formation from their two hydroxyl groups and renders the spatial arrangement of their peripheral CF₃ and CH₃ groups very different. The synthesized stereogenic scaffolds proved to be effective in catalyzing the asym. N-nitroso aldol reaction of enamines III [X = O, C, Y = (CH₂)_n, n = 1; X = C, Y = (CH₂)_n, n = 0] and nitrosobenzene. Compared to similar scaffolds without CF₃ groups, one of the atropisomers exhibits an increase in enantioselectivity in this reaction.(1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) (cas: 39637-74-6) were involved in the experimental procedure.

(1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) (cas: 39637-74-6 Synthetic Route of C10H13ClO3) is used as a resolving agent for alcohols as the diastereomeric esters by crystallization or chromatography and as a chiral derivatization reagent for determination of enantiomeric excess of alcohols and amines.

Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Cai, Libo;Zhu, Xiaoyi;Chen, Jiayi;Lin, Aijun;Yao, Hequan published 《Rh(III)-Catalyzed C-H activation/annulation of salicylaldehydes with sulfoxonium ylides for the synthesis of chromones》 in 2019. The article was appeared in 《Organic Chemistry Frontiers》. They have made some progress in their research.Application In Synthesis of (1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) The article mentions the following:

A rhodium(III)-catalyzed C-H activation/annulation of salicylaldehydes e.g., 2-OHC₆H₄CHO with sulfoxonium ylides RC(O)CH=S(O)(CH₃)CH₃ (R = Ph, t-Bu, cyclohexyl, thiophen-2-yl, etc.) has been developed for the formation of 2-substituted chromones e.g., I in good yields with broad functional group tolerance. The utility of this strategy was showcased by the late-stage modification of some biol. active mols. Moreover, structurally diverse 2,3-disubstituted chromones II (R¹ = Cl, CF₃, diethoxyphosphoroso, etc.) were also constructed by the C3 C-H functionalization reactions. To complete the study, the researchers used (1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) (cas: 39637-74-6) .

(1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) (cas: 39637-74-6 Application In Synthesis of (1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets)) is a chiral derivatizing agent. It can be prepared by reacting (-)-(1S,4R)-camphanic acid with thionyl chloride.

Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Yang, Jian;Zhao, He;Tan, Zhenda;Cao, Liang;Jiang, Huanfeng;Ci, Chenggang;Dixneuf, Pierre H.;Zhang, Min published 《syn-Selective Construction of Fused Heterocycles by Catalytic Reductive Tandem Functionalization of N-Heteroarenes》 in 2021. The article was appeared in 《ACS Catalysis》. They have made some progress in their research.Formula: C10H13ClO3 The article mentions the following:

To date, numerous methods have been successfully developed to functionalize N-heteroaryl C-H bonds. In contrast, dearomative tandem functionalization of N-heteroarenes is still a subject to be explored. Reported herein is an example on reductive dearomatization-induced tandem functionalization of N-heteroarenes by ruthenium catalysis, which offers a general method for diastereoselective construction of fused heterocycles featuring a cyclic syn-N, O-acetal motif from N-heteroarenes, phenols, and paraformaldehyde. Mechanistic study reveals that the products are formed via a tandem sequence of pyridyl C₃-benzylation and hydroxymethylation followed by C₂-aryloxylation of N-heteroarenium salts, proceeding with broad substrate scope, good functional group tolerance, high atom efficiency, and applicability for postfunctionalization of some biomedical mols.(1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) (cas: 39637-74-6) were involved in the experimental procedure.

(1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) (cas: 39637-74-6 Formula: C10H13ClO3) is a chiral derivatizing agent. It can be prepared by reacting (-)-(1S,4R)-camphanic acid with thionyl chloride.

Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Kikuchi, Katsuaki;Nakamura, Jun;Nagata, Yuuya;Tsuchida, Hiromu;Kakuta, Takahiro;Ogoshi, Tomoki;Morisaki, Yasuhiro published 《Control of Circularly Polarized Luminescence by Orientation of Stacked π-Electron Systems》 in 2019. The article was appeared in 《Chemistry – An Asian Journal》. They have made some progress in their research.Electric Literature of C10H13ClO3 The article mentions the following:

V-shaped bis(arylethynylarylethynyl) para-cyclophane I (R = 4-MeOC₆H₄) and its enantiomer were prepared to determine the relative circularly polarized luminescence of X-shaped and V-shaped luminescent mols. A racemic para-cyclophanediol was esterified with a camphanic chloride to yield a mixture of diastereomers which was brominated and then separated; hydrolysis of the camphanate esters, O-methylation, Sonogashira coupling with trimethylsilylacetylene, desilylation, and Sonogashira coupling with an iodoaryl alkyne yielded I (R = 4-MeOC₆H₄) and its enantiomer. I emitted intense circularly polarized luminescence (CPL); the sign of CPL emitted by a related X-shaped mol. was opposite to that of I, indicating that the sign of CPL can be controlled by the relative orientation of stacked fluorophores.(1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) (cas: 39637-74-6) were involved in the experimental procedure.

(1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) (cas: 39637-74-6 Electric Literature of C10H13ClO3) is a chiral derivatizing agent. It can be prepared by reacting (-)-(1S,4R)-camphanic acid with thionyl chloride.

Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Application of 39637-74-6In 2017, Huang, Zhongping;Williams, Russell B.;O’Neil-Johnson, Mark;Eldridge, Gary R.;Mangette, John E.;Starks, Courtney M. published 《A Total Synthesis of Bifidenone》. 《Journal of Organic Chemistry》published the findings. The article contains the following contents:

The first total synthesis of bifidenone (I), a novel natural tubulin polymerization inhibitor, has been achieved in 12 steps starting from com. available 1,4-dioxaspiro[4.5]decan-8-one. The synthesis includes a newly developed method to generate the dihydrobenzodioxolone core by palladium-catalyzed aerobic dehydrogenation. The three stereocenters were installed with an AD-mix-β dihydroxylation step followed by a late-stage palladium-catalyzed decarboxylation-allylation procedure. The absolute stereochem. was determined by single-crystal X-ray anal. of a derivative To complete the study, the researchers used (1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) (cas: 39637-74-6) .

(1S)-4,7,7-Trimethyl-3-oxo-2-oxabicyclo[2.2.1]heptane-1-carbonyl chloride(Chunks or pellets) (cas: 39637-74-6 Application of 39637-74-6) is used as a resolving agent for alcohols as the diastereomeric esters by crystallization or chromatography and as a chiral derivatization reagent for determination of enantiomeric excess of alcohols and amines.

Reference:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics