Category: 452-75-5

Kohlrausch, K. W. F. published an article in 1947, the title of the article was Studies of Raman effect. CLXXIII. Benzene derivatives. 30. Interpolated Raman spectra.Computed Properties of 452-75-5 And the article contains the following content:

Since a stepwise substitution of X = NH2, OH, Me, Cl, Br, I produces a regular frequency transition from one derivative to another, the spectra of members of the series not yet determined or undeterminable for any reason can be determined by interpolation. This is done for m- and o-C6H4(NH2)2, NH2C6H4OH, NH2C6H4F, FC6H4OH, BrC6H4OH, FC6H4Br, IC6H4NH2, IC6H4OH, IC6H4F, IC6H4Br, C6H4I2 1,3,5-F3C6H3, 1,3,5-Me2FC6H3, 1,3,2-Me2FC6H3, 1,2 3-Me2FC6H3, 1,3,4-Me2FC6H3, 1,2,4-Me2FC6H3, 1,4,2-Me2FC6H3, 1,4,2-MeClFC6H3, 1,4,2-Cl2FC6H3, 1,3,4-Cl2FC6H3. The experimental process involved the reaction of 4-Chloro-2-fluorotoluene(cas: 452-75-5).Computed Properties of 452-75-5

4-Chloro-2-fluorotoluene(cas:452-75-5) belongs to chlorides. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst. Computed Properties of 452-75-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On November 17, 1954, there was a patent about dyes.Computed Properties of 452-75-5 The title of the patent was Anthraquinone vat dyes. And the patent contained the following:

A series of anthraquinone vat dyes of the general formula I, where R is p-ClC6H4CONH, or 2,4-F(Cl)C6H3CONH, or 2,5-F(Cl)C6H3CONH and A represents a dicarboxylic acid residue, was prepared Thus, 1-amino-5-(4-chloro-2-fluorobenzamido)anthraquinone (II) 5.9 and p-ClC6H4COCl 4 parts heated 0.5 hr. with stirring in C6H3Cl3 150 at 200-5°, the mixture cooled and filtered, and the residue washed with EtOH and dried gave a dye which could be purified further with hypochlorite solution, red in concentrated H2SO4, dyed cotton from a Bordeaux-colored Na2S2O4 vat fast pure-yellow tints. The 5-Cl isomer of II gave similarly a dye yielding somewhat more reddish yellow dyeings. II, m. 279°, was prepared by the acylation of 1,5-diaminoanthraquinone with 2,4-F(Cl)C6H3COCl (III) or from 1-chloro-5-(4-chloro-2-fluorobenzamido)anthraquinone by replacing the 1-Cl atom by a p-MeC6H4SO2NH residue followed by cleavage. The 5-Cl isomer of II, m. 269°, was prepared in the same manner. 2,4-F(Cl)C6H3Me, b743 158°, obtained from 2,4-NH2(Cl)C6H3NH2 through the diazonium fluoborate, gave by KMnO4 oxidation 2,4-F(Cl)C6H3CO2H (IV), m. 205°. IV treated with SOCl2 yielded III, b14 105-6°. 2,5-H2N(Cl)C6H3Me was converted through the diazonium fluoborate to 2,5-F(Cl)C6H3Me, b741 156°, and further to 2,5-F(Cl)C6H3CO2H, m. 149-50°, which yielded 2,5-F(Cl)C6H3COCl, b15 103-4°. II 7.9, (COCl)2 1.27, and C6H3Cl3 150 parts heated with stirring during 2 hrs. to 150°, the mixture heated further to 190°, kept 1 hr. at 190-200°, cooled to 100°, and filtered, and the residue washed with EtOH and dried (it may be purified by boiling the neutral aqueous suspension with hypochlorite) gave I, where A = O:CC:O and R = 2,4-F(Cl)C6H3CONH, Bordeaux in concentrated H2SO4, which dyed cotton fast greenish yellow tints from a Bordeaux vat. II 4,p-C6H4(COCl)2 1, and C6H3Cl3 150 parts refluxed 2 hrs. with stirring gave I, where A = p-O:CC6H4C:O and R = 2,4-F(Cl)C6H3CONH, which dyed cotton fast pure yellow tints. Thianthrene dicarboxylic acid 1.12, SOCl2 6, pyridine 0.05, and C6H3Cl3 90 stirred 0.5 hr. at 80° and then 0.5 hr. at 120°, the excess SOCl2 and some of the solvent distilled off. the residual solution cooled to 100° and treated with II 3 parts, and the mixture heated 2 hrs. at 200-10°, cooled to 120°, and filtered gave I, where R = 2,4-F(Cl)C6H3CONH and A = thianthrenedicarbonyl, red in concentrated H2SO4, dyed cotton fast yellow tints. The experimental process involved the reaction of 4-Chloro-2-fluorotoluene(cas: 452-75-5).Computed Properties of 452-75-5

4-Chloro-2-fluorotoluene(cas:452-75-5) belongs to chlorides. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst. Computed Properties of 452-75-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Krishnan, R. S. published an article in 1945, the title of the article was Raman spectra of the second order in crystals. I. Calcite.Recommanded Product: 452-75-5 And the article contains the following content:

cf. C.A. 40, 5142.9. The importance of the second-order Raman spectra of crystals in providing information regarding the dynamical and optical properties of crystals is emphasized. The first- and second-order Raman spectra of calcite are photographed with Hg resonance radiation (λ 2536.5 A.). The frequency shifts and widths of the five lines of the first-order spectrum are accurately measured. The second-order spectrum is composed of 11 lines of varying intensity and width, some of which appear also in the infrared spectrum with very nearly the same ν. The frequencies have been assigned as some of the octaves and allowed combinations of the fundamental νν of the calcite lattice. The experimental process involved the reaction of 4-Chloro-2-fluorotoluene(cas: 452-75-5).Recommanded Product: 452-75-5

4-Chloro-2-fluorotoluene(cas:452-75-5) belongs to chlorides. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst. Recommanded Product: 452-75-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Green, John H. S.; Harrison, David John; Kynaston, W. published an article in 1971, the title of the article was Vibrational spectra of benzene derivatives. XII. 1,2,4-Trisubstituted compounds.Quality Control of 4-Chloro-2-fluorotoluene And the article contains the following content:

Measurements of the ir (3650-50 cm-1) and Raman spectra of 14 trisubstituted-benzenes with the 1, 2, 4 pattern of substitution are reported, and complete interpretation of the spectra are proposed. The experimental process involved the reaction of 4-Chloro-2-fluorotoluene(cas: 452-75-5).Quality Control of 4-Chloro-2-fluorotoluene

4-Chloro-2-fluorotoluene(cas:452-75-5) belongs to chlorides. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst. Quality Control of 4-Chloro-2-fluorotoluene

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Verma, V. N.; Rai, D. K. published an article in 1971, the title of the article was Electronic absorption spectrum of 2-fluoro-4-chlorotoluene in the vapor phase.Formula: C7H6ClF And the article contains the following content:

The electronic absorption spectrum of 2-fluoro-4-chlorotoluene vapor has been studied in the near-uv region and the assignments for the observed bands have been made assuming Cs symmetry for the mol. The strongest band at 36,517 cm-1 has been assigned as the (0,0) band and the bands have been analyzed in terms of 3 ground-state (150, 217, and 253 cm-1) and 9 excited-state (347, 491, 560, 711, 768, 933, 1012, 1054, and 1199 cm-1) frequencies. The experimental process involved the reaction of 4-Chloro-2-fluorotoluene(cas: 452-75-5).Formula: C7H6ClF

4-Chloro-2-fluorotoluene(cas:452-75-5) belongs to chlorides. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst. Formula: C7H6ClF

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On May 31, 2009, van Duijnhoven, Fraenzel J. B.; Bueno-De-Mesquita, H. Bas; Ferrari, Pietro; Jenab, Mazda; Boshuizen, Hendriek C.; Ros, Martine M.; Casagrande, Corinne; Tjonneland, Anne; Olsen, Anja; Overvad, Kim; Thorlacius-Ussing, Ole; Clavel-Chapelon, Francoise; Boutron-Ruault, Marie-Christine; Morois, Sophie; Kaaks, Rudolf; Linseisen, Jakob; Boeing, Heiner; Noethlings, Ute; Trichopoulou, Antonia; Trichopoulos, Dimitrios; Misirli, Gesthimani; Palli, Domenico; Sieri, Sabina; Panico, Salvatore; Tumino, Rosario; Vineis, Paolo; Peeters, Petra H. M.; van Gils, Carla H.; Ocke, Marga C.; Lund, Eiliv; Engeset, Dagrun; Skeie, Guri; Suarez, Laudina Rodriguez; Gonzalez, Carlos A.; Sanchez, Maria-Jose; Dorronsoro, Miren; Navarro, Carmen; Barricarte, Aurelio; Berglund, Goeran; Manjer, Jonas; Hallmans, Goeran; Palmqvist, Richard; Bingham, Sheila A.; Khaw, Kay-Tee; Key, Timothy J.; Allen, Naomi E.; Boffetta, Paolo; Slimani, Nadia; Rinaldi, Sabina; Gallo, Valentina; Norat, Teresa; Riboli, Elio published an article.HPLC of Formula: 452-75-5 The title of the article was Fruit, vegetables, and colorectal cancer risk: the European Prospective Investigation into Cancer and Nutrition. And the article contained the following:

Background: A high consumption of fruit and vegetables is possibly associated with a decreased risk of colorectal cancer (CRC). However, the findings to date are inconsistent. Objective: We examined the relation between self-reported usual consumption of fruit and vegetables and the incidence of CRC. Design: In the European Prospective Investigation into Cancer and Nutrition (EPIC), 452,755 subjects (131,985 men and 320,770 women) completed a dietary questionnaire in 1992-2000 and were followed up for cancer incidence and mortality until 2006. A multivariate Cox proportional hazard model was used to estimate adjusted hazard ratios (HRs) and 95% CIs. Results: After an average follow-up of 8.8 y, 2,819 incident CRC cases were reported. Consumption of fruit and vegetables was inversely associated with CRC in a comparison of the highest with the lowest EPIC-wide quintile of consumption (HR: 0.86; 95% CI: 0.75, 1.00; P for trend = 0.04), particularly with colon cancer risk (HR: 0.76; 95% CI: 0.63, 0.91; P for trend < 0.01). Only after exclusion of the first 2 y of follow-up were these findings corroborated by calibrated continuous analyses for a 100-g increase in consumption: HRs of 0.95 (95% CI: 0.91, 1.00; P = 0.04) and 0.94 (95% CI: 0.89, 0.99; P = 0.02), resp. The association between fruit and vegetable consumption and CRC risk was inverse in never and former smokers, but pos. in current smokers. This modifying effect was found for fruit and vegetables combined and for vegetables alone (P for interaction < 0.01 for both). Conclusions: These findings suggest that a high consumption of fruit and vegetables is associated with a reduced risk of CRC, especially of colon cancer. This effect may depend on smoking status. The experimental process involved the reaction of 4-Chloro-2-fluorotoluene(cas: 452-75-5).HPLC of Formula: 452-75-5

The Article related to colorectal neoplasms: epidemiology, colorectal neoplasms: prevention & control, diet, environment, europe: geographic, europe: epidemiology, female, follow-up studies, fruit, humans, incidence, life style, male, patient selection, reproducibility of results, surveys and questionnaires, time factors, vegetables and other aspects.HPLC of Formula: 452-75-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On February 1, 1996, Cantegril, Richard; Mortier, Jacques; Croisat, Denis; Peignier, Raymond published a patent.SDS of cas: 452-75-5 The title of the patent was Preparation of fungicidal 3-phenylpyrazole derivatives for treating propagative plant stock.. And the patent contained the following:

The fungicides (preparation given) are 3-phenylpyrazole derivatives I [ R1-R5 = H, halo, nitro, alkyl; Y= halo, nitro, etc.; Z= H, halo, C(:Z1)Z2, phosphoryl, etc.; Z1 = O, S, etc.; Z2 = H, halo, OH, SH, CN, etc.]. I is useful for protecting propagative plant stock from fungal diseases. The experimental process involved the reaction of 4-Chloro-2-fluorotoluene(cas: 452-75-5).SDS of cas: 452-75-5

The Article related to pyrazole derivative preparation fungicide, Agrochemical Bioregulators: Microbial and other aspects.SDS of cas: 452-75-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Unger, John B.; Lipshutz, Bruce H. published an article in 2007, the title of the article was Nickel-in-charcoal.COA of Formula: C7H6ClF And the article contains the following content:

Properties and applications of nickel-in-charcoal, a heterogeneous catalyst that has been applied to a number of group 10 transition metal mediated cross-coupling reactions are reviewed. The experimental process involved the reaction of 4-Chloro-2-fluorotoluene(cas: 452-75-5).COA of Formula: C7H6ClF

The Article related to review nickel preparation property reactivity safety, Inorganic Chemicals and Reactions: Reviews and other aspects.COA of Formula: C7H6ClF

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Tuncel, Gulten; Ergoren, Mahmut Cerkez; Baddal, Buket; Tulay, Pinar; Ozverel, Cenk Serhan; Guler, Emrah; Suer, Huseyin Kaya; Sayan, Murat; Sanlidag, Tamer published an article in 2022, the title of the article was Detection of SARS-CoV-2 N501Y mutation among SARS-CoV-2 variants of concern circulating in Northern Cyprus.Safety of 4-Chloro-2-fluorotoluene And the article contains the following content:

SARS-CoV-2 variants of concern (VOCs) carry signature mutations particularly in the spike protein. Most VOCs lineages that carry N501Y substitution have been reported to evade viral diagnostic tests and have impact on vaccine effectiveness. Therefore, monitoring the circulating variants represents a major requirement for a public health response worldwide. We aimed to investigate the prevalence of N501Y bearing SARS-CoV-2 samples in Northern Cyprus. Reverse transcription quant. PCR technique was used to identify N501Y mutation from 658 samples. Our results indicate that the proportion of N501Y-bearing lineages increased significantly from Jan. through May 2021 (45.2-75.5%) in the region. These results indicate that VOCs are dominant lineages in the country and highlight an alarming situation which require strict governmental measures to minimize COVID-19 morbidity and mortality. The experimental process involved the reaction of 4-Chloro-2-fluorotoluene(cas: 452-75-5).Safety of 4-Chloro-2-fluorotoluene

The Article related to detection sarscov2 n501y mutation variant concern circulating northern cyprus, b.1.1.7, b.1.351, covid-19, n5017y, p.1, sars-cov-2, variants of concern, Placeholder for records without volume info and other aspects.Safety of 4-Chloro-2-fluorotoluene

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On April 30, 2018, Sawatzky, Ryan S.; Stradiotto, Mark published an article.Recommanded Product: 452-75-5 The title of the article was (DPEPhos)Ni(mesityl)Br: An Air-Stable Pre-Catalyst for Challenging Suzuki-Miyaura Cross-Couplings Leading to Unsymmetrical Biheteroaryls. And the article contained the following:

The successful application of (DPEPhos)Ni(mesityl)Br as a pre-catalyst in the Suzuki-Miyaura cross-coupling of heteroaryl chlorides or bromides and heteroaryl boronic acids is reported. The use of (DPEPhos)Ni(mesityl)Br in this context allows for such reactions to be conducted under mild conditions (2 mol% Ni, 25 °C), including cross-couplings leading to unsym. biheteroaryls. Successful transformations of this type involving problematic pyridinyl boronic acid substrates (10 mol% Ni, 60 °C) are also described. The experimental process involved the reaction of 4-Chloro-2-fluorotoluene(cas: 452-75-5).Recommanded Product: 452-75-5

The Article related to heteroaryl halide heteroaryl boronic acid nickel suzuki miyaura, preparation unsym biheteroaryl, nickel suzuki miyaura cross coupling catalyst, General Organic Chemistry: Synthetic Methods and other aspects.Recommanded Product: 452-75-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics