Category: 54246-06-9

Anhoury, Marie L.; Crooy, Pierre; De Neys, Robert; Eliaers, Jacques published an article in 1974, the title of the article was Simple and mild method for reducing cyanohydrins to amino alcohols.HPLC of Formula: 54246-06-9 And the article contains the following content:

Reduction of 3,4,5-RR1R2C6H2CH(OH)CN (R = OMe, R1 OH, R2 = H, Cl, Br; R = OH, R1 = OMe, R2 = Cl, Br, I), prepared from the corresponding aldehyde by treatment with Na disulfite and KCN, with B2H6 gave 42-79% 3,4,5-RR1R2C6H2CH-(OH)CH2NH2 without loss of the halo substituent or the alc. OH groups. The experimental process involved the reaction of 3-Chloro-5-hydroxy-4-methoxybenzaldehyde(cas: 54246-06-9).HPLC of Formula: 54246-06-9

The Article related to reduction halohydroxymethoxybenzaldehyde cyanohydrin, benzaldehyde halo cyanohydrin reduction, phenethylamine hydroxy, alc amino, Noncondensed Aromatic Compounds: Aldehydes and Derivatives and other aspects.HPLC of Formula: 54246-06-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On December 18, 2008, Akatsuka, Hidenori; Sugama, Hiroshi; Awai, Nobumasa; Kawaguchi, Takayuki; Takahashi, Yoichi; Iijima, Toru; Shen, Jingkang; Xia, Guangxin; Xie, Jianshu published a patent.Recommanded Product: 3-Chloro-5-hydroxy-4-methoxybenzaldehyde The title of the patent was Preparation of morpholine derivatives as renin inhibitors. And the patent contained the following:

The title compounds I [R1 = alkyl (substituted with a group selected from (un)substituted alkoxy, OH, halo, etc.), (un)substituted aryl, (un)substituted heterocyclic group, etc.; R2 = alkyl (substituted with a group selected from (un)substituted alkoxy, OH, halo, etc.), (un)substituted aryl, (un)substituted heterocyclic group, etc.; T = methylene, carbonyl; R3 – R6 = H, (un)substituted carbamoyl, (un)substituted alkyl] are prepared Thus, (2R)-N-cyclopropyl-N-([4-(3-methoxypropoxy)-2-naphthyl]methyl)morpholine-2-carboxamide hydrochloride (II) was prepared in a multistep process starting from 4-hydroxy-2-naphthalenecarboxylic acid. II showed IC50 value of 30.2 nM against human renin. The experimental process involved the reaction of 3-Chloro-5-hydroxy-4-methoxybenzaldehyde(cas: 54246-06-9).Recommanded Product: 3-Chloro-5-hydroxy-4-methoxybenzaldehyde

The Article related to morpholine derivative preparation renin inhibitor, Heterocyclic Compounds (More Than One Hetero Atom): Oxazines (Including Morpholine) and other aspects.Recommanded Product: 3-Chloro-5-hydroxy-4-methoxybenzaldehyde

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics