Category: 5781-53-3

《Bicarbazole-based oxalates as photoinitiating systems for photopolymerization under UV-Vis LEDs》 was published in Journal of Polymer Science (Hoboken, NJ, United States) in 2020. These research results belong to Zhou, Ruchun; Jin, Ming; Malval, Jean-Pierre; Pan, Haiyan; Wan, Decheng. Application In Synthesis of Methyl 2-chloro-2-oxoacetate The article mentions the following:

Photoinitiators are critical to initiate chain reactions in photopolymerization For such applications, the absorption of photoinitiator must be compatible with the emission of light sources and enables the fast manufacturing of three-dimensional network or structures. Light-emitting diode (LED) is a new kind of energy-saving and environmental protection light source, exhibiting a substantial response in the near UV and visible range to replace the traditional mercury lamp and other light sources in photopolymerization Here, we introduce Me oxalate into bicarbazole chromophore (BiCz). By variation of the single or double substituents in the BiCz, we demonstrate that the absorption spectra can be adjusted and red shift to visible range and show good absorption in the near UV and visible range (365-475 nm). We explore their photochem. based on exptl. results and theor. calculations and the mechanism of photoreactions have been verified. The super photostability by themselves and good hydrogen abstraction ability from amine co-initiator make them as excellent near UV and visible light active photoinitiators. Critically, the photoinitiation of the free-radical polymerization of acrylate monomers with low content (0.1% concentration) upon LED irradiation at 365-475 nm, exhibits excellent application potential in light curing and other fields. In addition to this study using Methyl 2-chloro-2-oxoacetate, there are many other studies that have used Methyl 2-chloro-2-oxoacetate(cas: 5781-53-3Application In Synthesis of Methyl 2-chloro-2-oxoacetate) was used in this study.

Methyl 2-chloro-2-oxoacetate(cas: 5781-53-3) belongs to acyl chlorides. In the laboratory, acyl chlorides are generally prepared by treating carboxylic acids with thionyl chloride (SOCl2). The reaction is catalyzed by dimethylformamide and other additives.Application In Synthesis of Methyl 2-chloro-2-oxoacetate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Donnelly, Kian; Baumann, Marcus published their research in Chemical Communications (Cambridge, United Kingdom) in 2021. The article was titled 《A continuous flow synthesis of [1.1.1]propellane and bicyclo[1.1.1]pentane derivatives》.Synthetic Route of C3H3ClO3 The article contains the following contents:

A continuous flow process to generate [1.1.1]propellane on demand is presented rendering solutions of [1.1.1]propellane that can directly be derivatized into various bicyclo[1.1.1]pentane (BCP) species I [R = H, I, phenylsulfanyl, (butan-2-yloxy)carbonyl, etc.; R1 = I, (4-tert-butylphenyl)sulfanyl, N-(4-fluorophenyl)carbamoyl, etc.]. This was realized in throughputs up to 8.5 mmol h-1 providing an attractive and straightforward access to gram quantities of selected BCP building block I (R = R1 = I). Lastly, a continuous photochem. transformation of [1.1.1]propellane into valuable BCPs bearing mixed ester/acyl chloride moieties II (R2 = Me, Et, i-Pr, dodecyl, butan-2-yl) was developed. In the experimental materials used by the author, we found Methyl 2-chloro-2-oxoacetate(cas: 5781-53-3Synthetic Route of C3H3ClO3)

Methyl 2-chloro-2-oxoacetate(cas: 5781-53-3) belongs to acyl chlorides. In the laboratory, acyl chlorides are generally prepared by treating carboxylic acids with thionyl chloride (SOCl2). The reaction is catalyzed by dimethylformamide and other additives.Synthetic Route of C3H3ClO3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

In 2019,Analytical Chemistry (Washington, DC, United States) included an article by Tian, Zhenhao; Ding, Lele; Li, Kun; Song, Yunqing; Dou, Tongyi; Hou, Jie; Tian, Xiangge; Feng, Lei; Ge, Guangbo; Cui, Jingnan. Recommanded Product: Methyl 2-chloro-2-oxoacetate. The article was titled 《Rational Design of a Long-Wavelength Fluorescent Probe for Highly Selective Sensing of Carboxylesterase 1 in Living Systems》. The information in the text is summarized as follows:

Rational design of practical probes with excellent specificity and improved optical properties for a particular enzyme is always a big challenge. Herein, a practical and highly specific fluorescent probe for carboxylesterase 1 (CES1) was rationally designed using meso-carboxyl-BODIPY as the basic fluorophore based on the substrate preference and catalytic properties of CES1. Following mol. docking-based virtual screening combined with reaction phenotyping-based exptl. screening, we found that MMB (probe 7) exhibited the optimal combination of sensitivity and specificity toward human CES1 in contrast to other ester derivatives Under physiol. conditions, MMB could be readily hydrolyzed by CES1 and release MCB; such biotransformation brought great changes in the electronic properties at the meso position of the fluorophore and triggered a dramatic increase in fluorescence emission around 595 nm. Moreover, MMB was cell membrane permeable and was successfully applied to monitor the real activities of CES1 in various biol. samples including living cells, tissue slices, organs, and zebrafish. In summary, this study showed a good example for constructing specific fluorescent probe(s) for a target enzyme and also provided a practical and sensitive tool for real-time sensing of CES1 activities in complicated biol. samples. All these findings would strongly facilitate high-throughput screening of CES1 modulators and the studies on CES1-associated physiol. and pathol. processes. In the part of experimental materials, we found many familiar compounds, such as Methyl 2-chloro-2-oxoacetate(cas: 5781-53-3Recommanded Product: Methyl 2-chloro-2-oxoacetate)

Methyl 2-chloro-2-oxoacetate(cas: 5781-53-3) belongs to acyl chlorides. In the laboratory, acyl chlorides are generally prepared by treating carboxylic acids with thionyl chloride (SOCl2). The reaction is catalyzed by dimethylformamide and other additives.Recommanded Product: Methyl 2-chloro-2-oxoacetate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Poirot, Alexandre; Saffon-Merceron, Nathalie; Leygue, Nadine; Benoist, Eric; Fery-Forgues, Suzanne published an article in 2021. The article was titled 《Crystal structure of methyl 1,3-benzoxazole-2-carboxylate》, and you may find the article in Acta Crystallographica, Section E: Crystallographic Communications.Product Details of 5781-53-3 The information in the text is summarized as follows:

The title compound, C9H7NO3, crystallizes in the monoclinic (P21) space group. In the crystal, the almost planar mols. display a flattened herringbone arrangement. Stacking mols. are slipped in the lengthwise and widthwise directions and are linked by π interactions [d(Cg…Cg = 3.6640 (11)) Å]. The structure is characterized by strong C-H…N and weak C-H…O hydrogen bonds, and further stabilized by C-O…π interactions. The experimental process involved the reaction of Methyl 2-chloro-2-oxoacetate(cas: 5781-53-3Product Details of 5781-53-3)

Methyl 2-chloro-2-oxoacetate(cas: 5781-53-3) belongs to acyl chlorides. Lacking the ability to form hydrogen bonds, acyl chlorides have lower boiling and melting points than similar carboxylic acids. For example, acetic acid boils at 118 °C, whereas acetyl chloride boils at 51 °C. Like most carbonyl compounds, infrared spectroscopy reveals a band near 1750 cm−1.Product Details of 5781-53-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Solid polymer electrolytes from polyesters with diester sidechains for lithium metal batteries》 was written by Rosenbach, Dominic; Krimalowski, Alexander; Erabhoina, Harimohan; Thelakkat, Mukundan. Application In Synthesis of Methyl 2-chloro-2-oxoacetateThis research focused ontitanium oxide polyester solid polymer electrolyte lithium metal battery. The article conveys some information:

A series of polymethacrylates and polyacrylates carrying diester side chain moieties with varying alkyl spacer lengths are designed, synthesized, and evaluated as solid polymer electrolytes (SPEs) in lithium metal batteries (LMBs). These amorphous polymers with glass transition temperatures in the range of -58 to +32 °C are tested as SPEs in combination with LiTFSI or LiFSI. At an optimum salt concentration of 25 wt%, ionic conductivities up to 10-4 S cm-1 at 70 °C are achieved. These SPEs reveal high lithium transport numbers (0.5-0.7) and high electrochem. stability (5.4 V vs. Li/Li+) as determined by LSV. In combination with an ultrathin polyimide membrane and 10 wt% TiO2 nanoparticles, dendrite-free plating/stripping at 40 and 70 °C is realized in sym. Li|SPE|Li cells. Detailed extended distribution of relaxation times (eDRT) anal. of impedance measurements is employed for understanding the diverse cell processes. In solvent-free LMBs comprising a polyimide membrane soaked with the nanocomposite polyester electrolyte, lithium metal foil as the anode and an optimized LiFePO4 cathode, a very high initial specific discharge capacity of 152 mA h g- 1 (at 0.2C, 70 °C), excellent capacity retention of 94% after 100 cycles (at 1C, 70 °C) and negligible capacity fading even at 2C (96% retention after 300 cycles) are demonstrated. These novel polyester-based SPEs exhibit high cycling stability at 40 °C, making them highly attractive for room temperature applications. In the experimental materials used by the author, we found Methyl 2-chloro-2-oxoacetate(cas: 5781-53-3Application In Synthesis of Methyl 2-chloro-2-oxoacetate)

Methyl 2-chloro-2-oxoacetate(cas: 5781-53-3) belongs to acyl chlorides. Lacking the ability to form hydrogen bonds, acyl chlorides have lower boiling and melting points than similar carboxylic acids. For example, acetic acid boils at 118 °C, whereas acetyl chloride boils at 51 °C. Like most carbonyl compounds, infrared spectroscopy reveals a band near 1750 cm−1.Application In Synthesis of Methyl 2-chloro-2-oxoacetate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics