Adding a certain compound to certain chemical reactions, such as: 61881-19-4, name is 2,2,2-Trifluoro-N-phenylacetimidoyl chloride, belongs to chlorides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 61881-19-4, Formula: C8H5ClF3N
To 1,3,4,5-tetra-O-benzoylfructose 3 (594 mg, 1 mmol) and Nphenyl trifluoroacetimidoyl chloride (0.45 mL, 3 mmol) in acetone (AR grade, 8 mL) was added K2CO3 (410 mg, 3 mmol), and the mixture was stirred at rt for 2 h. The mixture was filtered, concentrated, and the residuewas purified by column chromatography (hexane/EtOAc 7:1) to obtain 4 as white foam (756 mg, 98%).
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Reference:
Article; Lin, Feng; Lian, Gaoyan; Xu, Qiulong; Zhu, Xiaofeng; Tetrahedron; vol. 69; 3; (2013); p. 1128 – 1132;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics