Category: 6249-56-5

Pfeifer, Annett published the artcileSynthesis and characterization of novel water-soluble and bactericidic cationic starch esters, Category: chlorides-buliding-blocks, the publication is Starch/Staerke (2017), 69(9-10), n/a, database is CAplus.

Novel water-soluble cationic starch esters, namely starch-4-(N,N,N-trimethylammonium)butyrate chloride with high degree of substitution (DS) of up to 0.7 could be easily prepared by conversion of starch of different molar mass with the imidazolide of 3-carboxypropyltrimethylammonium chloride (CPTMACl) homogeneously in DMSO (DMSO). The products were characterized in detail by FTIR and NMR spectroscopy, including two-dimensional methods. The cationic starch esters possess a high antibacterial activity.

Starch/Staerke published new progress about 6249-56-5. 6249-56-5 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst,Inhibitor,Natural product, name is 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride, and the molecular formula is C7H16ClNO2, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Blunden, Gerald published the artcileNMR spectra of betaines from marine algae, COA of Formula: C7H16ClNO2, the publication is Magnetic Resonance in Chemistry (1986), 24(11), 965-71, database is CAplus.

The ¹H and ¹³C NMR spectroscopic characteristics of a range of betaines (i.e. quaternary ammonium and tertiary sulfonium compounds), most of which are found in marine algae, are described. The spectral features are an important aid in the identification of these compounds In the ¹³C NMR spectra, some (¹⁴N, ¹³C) couplings are clearly observed The fast atom bombardment of some of these compounds are also described.

Magnetic Resonance in Chemistry published new progress about 6249-56-5. 6249-56-5 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst,Inhibitor,Natural product, name is 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride, and the molecular formula is C7H16ClNO2, COA of Formula: C7H16ClNO2.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Tan, Derek S. published the artcileSynthesis and Preliminary Evaluation of a Library of Polycyclic Small Molecules for Use in Chemical Genetic Assays, Safety of 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride, the publication is Journal of the American Chemical Society (1999), 121(39), 9073-9087, database is CAplus.

(-)-Shikimic acid, was converted into both enantiomers of 2-hydroxyoxabicyclo[4.1.0]hept-3-ene-4-carboxylic acid which were attached to a solid support via a photocleavable linker. Tandem acylation-1,3-dipolar cycloaddition with nitrones yielded tetracyclic templates I. After development of several efficient coupling reactions of I and completion of extensive validation protocols, a split-pool synthesis yielded a binary encoded library calculated to contain 2.18 million polycyclic compounds These compounds are compatible with miniaturized cell-based forward chem. genetic assays designed to explore biol. pathways and reverse chem. genetic assays designed to explore protein function. As a simple illustration of the potential of these compounds, several were shown to activate a TGF-β-responsive reporter gene in mammalian cells.

Journal of the American Chemical Society published new progress about 6249-56-5. 6249-56-5 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst,Inhibitor,Natural product, name is 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride, and the molecular formula is C12H15NO, Safety of 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Vega Erramuspe, Iris Beatriz published the artcileAdvanced Cellulose Fibers for Efficient Immobilization of Enzymes, Synthetic Route of 6249-56-5, the publication is Biomacromolecules (2016), 17(10), 3188-3197, database is CAplus and MEDLINE.

Biocatalytic pulp fibers were prepared using surface functionalization of bleached kraft pulp with amino groups (F) and further immobilization of a crosslinked glucose oxidase (G^*) from Aspergillus niger. The crosslinked enzymes (G^*) were characterized using x-ray spectroscopy, FTIR spectroscopy, dynamic scanning calorimetry and dynamic light scattering. According to standard assays, the G^* content on the resulting fibers (FG^*) was 11 mg/g of fiber, and the enzyme activity was 215 U/g. The results from confocal- and stimulated emission depletion microscopic techniques demonstrated that G^* did not penetrate the interlayers of fibers. The benefit of pulp fiber functionalization was evident in the present case, as the introduction of amino groups allowed the immobilization of a larger amount of enzymes and rendered more efficient systems. Using the approach described here, several advanced materials from wood pulp fibers and new bioprocesses might be developed by selecting the correct enzyme for the target applications.

Biomacromolecules published new progress about 6249-56-5. 6249-56-5 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst,Inhibitor,Natural product, name is 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride, and the molecular formula is C14H21BO3, Synthetic Route of 6249-56-5.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Albert, Anastasia published the artcileCharacteristics of Low-Temperature Plasma Ionization for Ambient Mass Spectrometry Compared to Electrospray Ionization and Atmospheric Pressure Chemical Ionization, Application of 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride, the publication is Analytical Chemistry (Washington, DC, United States) (2012), 84(24), 10657-10664, database is CAplus and MEDLINE.

Ambient desorption/ionization mass spectrometry (ADI-MS) is an attractive method for direct anal. with applications in homeland security, forensics, and human health. For example, low-temperature plasma probe (LTP) ionization was successfully used to detect, e.g., explosives, drugs, and pesticides directly on the target. Despite the fact that the field is gaining significant attention, few attempts were made to classify ambient ionization techniques based on their ionization characteristics and performance compared to conventional ionization sources used in mass spectrometry. Relative ionization efficiencies (RIEs) for a large group of compound families were determined with LTP-Orbitrap-MS and compared to those obtained with electrospray ionization mass spectrometry (ESI-MS) and atm. pressure chem. ionization mass spectrometry (APCI-MS). RIEs were normalized against 1 reference compound used across all methods to ensure comparability of the results. Typically, LTP analyte ionization through protonation/deprotonation (e.g., 4-acetamidophenol) was observed; in some cases (e.g., acenaphthene) radicals were formed. Amines, amides, and aldehydes were ionized successfully with LTP. A benefit of LTP over conventional methods is the possibility to successfully ionize PAHs and imides. The studied model compounds could be detected by neither APCI nor ESI. LTP is a relatively soft ionization method because little fragmentation of model compounds was observed It is considered to be an attractive method for the ionization of low mol. weight compounds over a relatively wide polarity range.

Analytical Chemistry (Washington, DC, United States) published new progress about 6249-56-5. 6249-56-5 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst,Inhibitor,Natural product, name is 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride, and the molecular formula is C7H16ClNO2, Application of 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Broekhuysen, J. published the artcileAnalytical separation of various betaines and quaternary ammonium derivatives by paper electrorheophoresis, COA of Formula: C7H16ClNO2, the publication is Annales de Biologie Clinique (1961), 533-47, database is CAplus and MEDLINE.

Data are given on the electrophoretic behavior on paper of the betaine from crotonic acid and Me₃N, glycine betaine, γ-butyrobetaine, carnitine, choline, creatine, creatinine, Et ester of carnitine, β-homocholine, neurine, phosphocholine, phosphoethanolamine, tetramethylammonium ion, and Me₃N⁺. The elec. mobility was demonstrated to be a simple function of the specific charge on the ion, a relation which holds also for closely related compounds such as creatine and creatinine which were separated sharply by electrorheophoresis. The specific charges differed greatly at different pH values. It was possible, when dissociation constants were known, to determine the pH for optimum separation of the different compounds The advantage of electrorheophoresis is that the rate of migration may be modified by changing the ionic force of the buffer used without altering the pH. The method is applicable to the separation of substances of biol. origin from attendant impurities.

Annales de Biologie Clinique published new progress about 6249-56-5. 6249-56-5 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst,Inhibitor,Natural product, name is 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride, and the molecular formula is C7H16ClNO2, COA of Formula: C7H16ClNO2.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Szafran, M. published the artcileDifferences in proton-proton coupling constants of N⁺-CH₂-CH₂ protons of some betaines, N⁺-(CH₂)_2-3-COO^–, and their complexes in aqueous solution, Safety of 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride, the publication is Journal of Molecular Structure (2001), 555-564, database is CAplus.

Synthesis and ¹H NMR spectra in D₂O of 4 betaines and 19 betaine complexes with mineral acids containing 2 or 3 CH₂ groups in the tether, N⁺-(CH₂)_n-COO^–, n=2,3, and diverse volume of the pos. charged groups are reported. In compounds containing three CH₂ groups in the tether and three substituents at the nitrogen atom or α, α’-disubstituted pyridine ring, a characteristic multiplet for an AA’MM’X₂ spin system is observed This is consistent with preference for trans conformation (68-85%). In the spectra of compounds with two CH₂ groups in the tether or three CH₂ groups and unsubstituted pyridine ring, the multiplet changes to a triplet and gives apparent A₂X₂ and A₂M₂X₂ spectra, resp., consistent with no significant conformational preference. Both the number of CH₂ groups in tether and the bulkiness of the charged groups are responsible for the observed differences of N⁺CH₂ multiplicity and reflect changes in conformational preferences. According to the PM3 calculations, in the gas phase a gauche-like conformer is more stable than the trans, but in aqueous solution it is reverse.

Journal of Molecular Structure published new progress about 6249-56-5. 6249-56-5 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst,Inhibitor,Natural product, name is 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride, and the molecular formula is C24H12, Safety of 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Verma, M. R. published the artcileA paper-chromatographic method for the identification of 1- and 2-naphthols when present together, Synthetic Route of 6249-56-5, the publication is Journal of Chromatography (1960), 197-9, database is CAplus.

1-Naphthol (I) and 2-naphthol (II) dissolved in alc., spotted on filter paper, and coupled in situ with cold alk. 0.2M di azotized di-Na 2-naphthylamine-5,7-disulfonate gave the following R_f values, resp., with several eluants: iso-AmOH-EtOH-NH₄OH (40:40:25) 0.14, 0.28; iso-AmOH-EtOH-H₂O (40:40:25) 0.10, 0.24; iso-BuCOMe-EtOH (70:30) saturated with 10% NH₃ 0.04, 0.18. Rose-red spots were formed with both I and II in each eluant.

Journal of Chromatography published new progress about 6249-56-5. 6249-56-5 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst,Inhibitor,Natural product, name is 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride, and the molecular formula is C9H8O4, Synthetic Route of 6249-56-5.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Hodgson, Ernest published the artcileDietary choline requirements, phospholipids, and development in Phormia regina, Name: 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride, the publication is Comparative Biochemistry and Physiology (1969), 29(1), 343-59, database is CAplus.

Twenty-six compounds were tested for their ability to support growth and development when fed, in lieu of choline, to P. regina. Sixteen supported larval growth and previous findings on structure-function relation in choline substitutes were confirmed. Only ten compounds permitted appreciable formation of puparia and only four of these permitted the emergence of normal adults. Thus, the structural requirements for postlarval development are much more rigorous than those for larval growth. No compound was as effective as choline. All compounds which support larval growth are incorporated into phospholipids analogous to phosphatidylcholine, indicating that the cytidine pathway for phospholipid synthesis is relatively nonspecific. Isopropylaminoethanol is a growth inhibitor when fed to P. regina larvae.

Comparative Biochemistry and Physiology published new progress about 6249-56-5. 6249-56-5 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst,Inhibitor,Natural product, name is 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride, and the molecular formula is C7H16ClNO2, Name: 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Paolino, D. published the artcilePolyaspartylhydrazide copolymer-based supramolecular vesicular aggregates as delivery devices for anticancer brugs, Quality Control of 6249-56-5, the publication is Biomacromolecules (2008), 9(4), 1117-1130, database is CAplus and MEDLINE.

In this paper we report on three different hydrophilic copolymers based on α,β-polyaspartylhydrazide (PAHy) bearing butyric groups in the side chain (C₄) (PAHy-C₄) or a combination of butyric groups and pos. charged residues ((carboxypropyl)trimethylammonium chloride, CPTACl) (PAHy-C₄-CPTA) that were synthesized and used for the preparation of new supramol. vesicular aggregates (SVAs) containing gemcitabine as an antitumor drug. Gemcitabine-loaded SVAs containing synthesized PAHy derivatives were characterized from the physicochem. and technol. point of view and the in vitro toxicity and anticancer activity on two different human cancer cell lines, i.e., CaCo-2 (human colon carcinoma) and ARO (human anaplastic thyroid carcinoma) cells, were also evaluated. Moreover, considering that carrier-cell interaction is an important factor to achieve an improvement of anticancer drug activity, confocal laser scanning microscopy and flow cytometric experiments were carried out on the two different cancer cell lines.

Biomacromolecules published new progress about 6249-56-5. 6249-56-5 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst,Inhibitor,Natural product, name is 3-Carboxy-N,N,N-trimethylpropan-1-aminium chloride, and the molecular formula is C7H16ClNO2, Quality Control of 6249-56-5.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics