Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 626-43-7, name is 3,5-Dichloroaniline, A new synthetic method of this compound is introduced below., HPLC of Formula: C6H5Cl2N
Ethyl 2-( ( 3, 5-dichlorophenyl) amino) acetate : A mixture of 3,5-dichloroaniline (0277) (500 mg, 3.51 mmol), ethyl 2-bromoacetate (585.6 mg, 3.51 mmol) and DIEA (1.36 g,10.52 mmol) in MeCN (5 mL) was heated to 80 C and stirred for 16 h. The reaction solution was concentrated to give ethyl (3,5-dichlorophenyl)glycinate (800 mg, yield: 100%) as a yellow solid. LCMS: [M+H]+= 248.1
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; RECREO PHARMACEUTICALS LLC; ZHANG, Jing; WANG, Xiang; PODOLL, Jessica, D.; (207 pag.)WO2020/37155; (2020); A1;,
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