Category: 6276-54-6

Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 6276-54-6, Name is 3-Chloropropan-1-amine hydrochloride, molecular formula is C3H9Cl2N, belongs to chlorides-buliding-blocks compound. In a document, author is Arora, Aayushi, introduce the new discover, SDS of cas: 6276-54-6.

Catalytically active nanosized Pd9Te4 (telluropalladinite) and PdTe (kotulskite) alloys: first precursor-architecture controlled synthesis using palladium complexes of organotellurium compounds as single source precursors

Several intermetallic binary phases of Pd-Te including Pd3Te2, PdTe, PdTe2, Pd9Te4, Pd3Te, Pd2Te, Pd20Te7, Pd8Te3, Pd7Te2, Pd7Te3, Pd4Te and Pd17Te4 are known, and negligible work (except few studies on PdTe) has been done on exploring applications of such phases and their fabrication at nanoscale. Hence, Pd(ii) complexes Pd(L1)Cl-2 and Pd(L2-H)Cl (L1): Ph-Te-CH2-CH2-NH2 and L2: HO-2-C6H4-CH = N-CH2CH2-Te-Ph were synthesized. Under similar thermolytic conditions, complex Pd(L1)Cl-2 with bidentate coordination mode of ligand provided nanostructures of Pd9Te4 (telluropalladinite) whereas Pd(L2-H)Cl with tridentate coordination mode of ligand yielded PdTe (kotulskite). Bimetallic alloy nanostructures possess high catalytic potential for Suzuki coupling of aryl chlorides, and reduction of 4-nitrophenol. They are also recyclable upto six reaction cycles in Suzuki coupling.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 6276-54-6. SDS of cas: 6276-54-6.

One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, such as the rate of change in the concentration of reactants or products with time. 6276-54-6, Name is 3-Chloropropan-1-amine hydrochloride, formurla is C3H9Cl2N. In a document, author is Lu, Yang, introducing its new discovery. SDS of cas: 6276-54-6.

Polyamide Thin Films Grown on PD/SWCNT-Interlayered-PTFE Microfiltration Membranes for High-Permeance Organic Solvent Nanofiltration

Porous polymeric support membranes with outstanding organic solvent resistance are highly required for fabricating thin-film composite (TFC) organic solvent nanofiltration (OSN) membranes. In this work, we report the fabrication of a high-permeance TFC-OSN membrane by the use of a polytetrafluoroethylene (PTFE) microfiltration membrane loaded with single-walled carbon nanotubes coated by a polydopamine (PD/SWCNT) network film (named the PD/SWCNT/PTFE composite membrane) as the support. Through interfacial polymerization between m-phenylenediamine and trimesoyl chloride, a polyamide (PA) thin film has successfully grown on the surface of the PD/SWCNT/PTFE composite membrane. The resulting PA TFC-OSN membrane exhibits a high methanol permeance up to 13.2 L m(-2) h(-1) bar(-1) with a rejection rate of 89.6% to 6-hydroxy-2-naphthalenesulfonic acid sodium salt (HNSA, M-w = 246.21). Moreover, the rejection rates of the PA TFC-OSN membrane to various dyes remain unchanged before and after DMF activation, indicating that it possesses an excellent resistance to organic solvents.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 6276-54-6 help many people in the next few years. SDS of cas: 6276-54-6.

Synthetic Route of 6276-54-6, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 6276-54-6, Name is 3-Chloropropan-1-amine hydrochloride, SMILES is NCCCCl.[H]Cl, belongs to chlorides-buliding-blocks compound. In a article, author is Peng Wei, introduce new discover of the category.

Oligomerization and Polymerization of Isoprene Catalyzed by Alkylaluminium with Different Structures

Alkylaluminium (AlR3), as co-catalyst component in Ziegler-Natta catalytic system, plays important roles in the alkylation, forming and changing the structure and concentration of active centers through the reduction and reversible adsorption-desorption reactions with the metal compound of the catalyst, acting as chain transfer agent, etc. However, the alkylaluminium itself do have the catalytic effect on the conjugated diene monomers. In this article, alkylaluminium with different structures such as triethylaluminium (AlEt3), triisobutylaluminium (Al(i-Bu)(3)), diisobutylaluminium hydride (AlH(i-Bu)(2)), diethylaluminium chloride (AlEt2Cl), ethylaluminium dichloride (AlEtCl2) were used to catalyze isoprene oligomerization and polymerization. The effects of the structure and concentration of alkylaluminiums (n(Al)/n(M)=7 x 10(-5), 35 x 10(-5), 350 x 10(-5), 1050 x 10(-5)) on the catalytic behaviors of isoprene were studied. The microstructure (trans-1,4 and cis-1,4), molecular weight and molecular weight distribution of the products were characterized by H-1 nuclear magnetic resonance spectroscopy (H-1 NMR), gel permeation chromatography (GPC) and gas chromatography-mass spectrometry (GC-MS). It was found that alkylaluminium could initiate oligomerization and cationic polymerization of isoprene under the minor incorporation of H2O, which were affected greatly by the structure and concentration of alkylaluminium. Using AIEtCl(2) led to the highest catalytic activity and produced products containing more linear polymers with mixed cis-1,4/trans-1,4 structures when n(Al)/n(M)=1050 x 10(-5). The Al(i-Bu)(3) and AlH(i-Bu)(2) didn’t have basically cation initiation ability, which led to isoprene oligomerization. The alkylaluminium with n(Al)/n(M)<= 350 x10(-5) had negligible influence on the isoprene polymerization and oligomerization. And lower or higher alkylaluminium concentration were not beneficial to obtain polyisoprene with high molecular weight. The catalytic mechanism of alkylaluminium on isoprene was discussed, which provided a further understanding on the catalytic behavior of alkylaluminium components in Ziegler-Natta catalyst and the effect of alkylaluminium on polymers. Synthetic Route of 6276-54-6, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 6276-54-6 is helpful to your research.

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Approach to generating the right active phase in the Direct synthesis of trimethoxysilanes using the CuCl-Cu2O catalyst

The direct synthesis of trimethoxysilane (M3) by the reaction of Si with methanol over the Cud catalyst often generates a large amount of erosive HCl gas, causing severe environmental pollution. Thus, it calls for the development of greener and more efficient composite catalysts. In this work, to reduce the amount of CuCl, we employed three pretreatment methods to activate the contact mass of Si powder and the composite catalyst of CuCl and Cu2O. It was found that the contact mass activated by argon (Ar), hydrogen argon (H-2/Ar) and methyl chloride (CH3Cl), respectively, exhibited different catalytic performances: the highest Si conversion (34.1%) and M3 yield (24.0%) were obtained on the sample activated by CH3Cl. Notably, the M3 yield was increased 8-fold than that of the un-activated sample. The X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS) studies revealed that different activation methods led to the generation of different kinds of CuxSi phases, such as Cu3Si and Cu4Si, both of which gradually transformed into Cu15Si4 during the reaction process. Pretreatment of the contact mass with CH3Cl promoted the formation of CuxSi, which contributed to the generation of more Cu15Si4 active phase, and finally to the superior catalytic performance.

If you are hungry for even more, make sure to check my other article about 6276-54-6, HPLC of Formula: C3H9Cl2N.

Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 6276-54-6, Name is 3-Chloropropan-1-amine hydrochloride, molecular formula is C3H9Cl2N, belongs to chlorides-buliding-blocks compound, is a common compound. In a patnet, author is Si, Wei, once mentioned the new application about 6276-54-6, Application In Synthesis of 3-Chloropropan-1-amine hydrochloride.

AT1R/GSK-3 beta/mTOR Signaling Pathway Involved in Angiotensin II-Induced Neuronal Apoptosis after HIE Both In Vitro and In Vivo

Objective. The focus of the present study is to evaluate the effects of Angiotensin II (Ang II) on neuronal apoptosis after HIE and the potential underlying mechanisms. Methods. Primary neonatal rat cortical neurons were used to study the oxygen-glucose deprivation (OGD) cell model. The expressions of Ang II, AT1R, GSK-3 beta, p-GSK-3 beta, mTOR, p-mTOR, Bax, Bcl-2, and cleaved caspase-3 were detected via western blot. IF and flow cytometry were used to evaluate neuronal apoptosis. Hypoxic-ischemic encephalopathy (HIE) was established to evaluate the therapeutic effects of Ang II in vivo. Cerebral infarction areas were detected by 2,3,5-Triphenyltetrazolium chloride staining. The righting and geotaxis reflexes were also recorded. In addition, Fluoro-Jade C staining and TUNEL staining were performed to evaluate neuronal degeneration and apoptosis. Results. Ang II significantly increased the rate of neuronal apoptosis, upregulated the expression of cleaved caspase-3, and downregulated Bcl-2/Bax ratio after OGD insult. For vivo assay, the expressions of endogenous Ang II and AT1R gradually increased and peaked at 24 h after HIE. Ang II increased NeuN-positive AT1R cell expression. In addition, Ang II increased the area of cerebral infarction, promoted neuronal degeneration and apoptosis, aggravated neurological deficits on righting and geotaxis reflexes, and was accompanied by increased expressions of phosphorylated GSK-3 beta and mTOR. The application of valsartan (Ang II inhibitor) or SB216763 (GSK-3 beta inhibitor) reversed these phenomena triggered by Ang II following HIE. Conclusion. Ang II increased neuronal apoptosis through the AT1R/GSK-3 beta/mTOR signaling pathway after experimental HIE both in vitro and in vivo, and Ang II may serve as a novel therapeutic target to ameliorate brain injury after HIE.

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, 6276-54-6. The above is the message from the blog manager. Application In Synthesis of 3-Chloropropan-1-amine hydrochloride.

Related Products of 6276-54-6,Some common heterocyclic compound, 6276-54-6, name is 3-Chloropropan-1-amine hydrochloride, molecular formula is C3H9Cl2N, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

To sulfuryl chloride (5 g, 30.05 mmol) in acetonitrile (30 mE), was added 3-chloropropyl amine hydrochloride (486 mg, 5.00 mmol). The reaction mixture was allowed to react over 18 hr at 75-80 C. After the completion of the reaction, the resultant was concentrated under reduced pressure, extracted with ether and then kept under vacuum for a long time to remove remained sulfuryl chloride, giving 3-chloropropylsulfamoyl chloride that was used without thrther purification.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 3-Chloropropan-1-amine hydrochloride, its application will become more common.

Reference:
Patent; KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY; Kim, Ki Young; Ahn, Jin Hee; Kang, Seung Kyu; Rhee, Sang Dal; Bae, Myung Ae; Ahn, Sung Hoon; Kim, Hee Youn; Jung, Won Hoon; Kang, Nam Sook; US2014/24636; (2014); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Related Products of 6276-54-6, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 6276-54-6 as follows.

Preparation of Compound 1aDi-tert-butyl-dicarbonate (0.228 g, 1.04 mmol) and sodium hydroxide (0.096 g, 2.4 mmol) were added to a cooled solution of 3-chloropropan-1-amine (0.15 g, 1.04 mmol) in water (10 ml) and THF (10 ml). The resulting mixture was stirred overnight at 0 C. The aqueous layer was then extracted with ethyl acetate (10 ml¡Á4). The combined organic layer was washed with brine (25 ml), dried over sodium sulfate and concentrated. The residue was then purified by column chromatography on silica gel to afford 0.306 g of colorless oil. Yield: 94.0%. 1H NMR (300 MHz, CDCl3) delta1.39 (s, 9H), 81.91 (m, 2H), 83.23 (m, 2H), delta3.53 (t, J=6.4 Hz, 2H), 64.89 (s, 1H). 13C NMR (75 MHz, CDCl3) delta (ppm): 156.0, 79.2, 42.3, 37.9, 32.6, 28.3. MS (ESI): m/z calcd for C8H16ClNO2 193.09, found 193.52 [M+H]+

According to the analysis of related databases, 6276-54-6, the application of this compound in the production field has become more and more popular.

Reference:
Patent; NANYANG TECHNOLOGICAL UNIVERSITY; US2012/288884; (2012); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Synthetic Route of 6276-54-6, A common heterocyclic compound, 6276-54-6, name is 3-Chloropropan-1-amine hydrochloride, molecular formula is C3H9Cl2N, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

An aqueous sodium dicarbonate solution (3.5 g in 57 ml of water) and solid sodium chloride (7.5 g) were added at 0 C. to a suspension of 3-chloropropylamine hydrochloride (38 mmol) in DCM (77 ml), and the mixture was stirred for 30 minutes. A solution of Boc anhydride (1.2 eq.) in dichloromethane (20 ml) was then slowly added dropwise. The reaction mixture was stirred overnight at RT. The reaction mixture was extracted with dichloromethane, and the org. phase was washed with water and sat. sodium chloride solution, dried over sodium sulfate (anhydrous) and concentrated. The desired product was used in the next stage without being purified further.Yield: 83.7%

The synthetic route of 6276-54-6 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Gruenenthal GmbH; US2010/222324; (2010); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 6276-54-6, name is 3-Chloropropan-1-amine hydrochloride, A new synthetic method of this compound is introduced below., SDS of cas: 6276-54-6

Large-Scale Synthesis of 3-Azidopropan-1-amineA solution of sodium azide (195 g, 3.0 mol) in deionized water (800 mL) was added into a three-neck round-bottom flask equipped with a condenser. Then 3-chloropropylamine hydrochloride (195 g, 1.5 mol) dissolved in 300 mL of deionized water was added. After continued stirring at 75-78 C. for 96 h, the white precipitate (NaCl) was removed as a byproduct from the reaction mixture by filtration. The yellow filtrate was basified with aqueous NaOH to pH?10-11 and further extracted with diethyl ether (5¡Á200 mL). The organic fraction was dried over anhydrous MgSO4 overnight, filtered, concentrated on a rotary evaporator, and distilled under reduced pressure to produce a colorless oil. The yield was: 108.4 g, 72%. 1H NMR (CDCl3, delta, ppm): 3.35 (t, 2H, CH2N3), 2.78 (t, 2H, NH2CH2), 1.71 (p, 2H, CH2CH2CH2), 1.27 (s, 2H, NH2).

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Patent; Zhamu, Aruna; Jang, Bor Z.; US2013/5917; (2013); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Related Products of 6276-54-6,Some common heterocyclic compound, 6276-54-6, name is 3-Chloropropan-1-amine hydrochloride, molecular formula is C3H9Cl2N, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Compound 8: 3-Chloropropylamine HCl (6.5 g, 0.05 mol) and sodium azide (10 g, 0.15 mol) were dissolved in 50 mL water. The reaction proceeded at 80 C. for 48 hours. 10 N NaOH (6 mL) was then added, and the product was extracted with ether and concentrated in vacuo. Bulb to bulb distillation (Bp=65-75 C. at 20-22 ton) afforded a clear oil (4 g, 80%). 1H-NMR (500 MHz, CDCl3): delta 3.38 (t, J=6.7 Hz, 2H), 2.81 (t, J=6.8 Hz, 2H), 1.73 (p, J=6.8 Hz, 2H).

The synthetic route of 6276-54-6 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; The Rockefeller University; STELLER, Hermann; SANDU, Cristinel; KELKAR, Anshuman; GANGADHAR, Nidhi; US2013/244325; (2013); A1;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics