Category: 6294-17-3

Electron-beam patterned monolayer-protected gold nanoparticle interface layers on a chemiresistor vapor sensor array was written by Steinecker, William H.;Kim, Sun Kyu;Bohrer, Forest I.;Farina, Lee;Kurdak, Cagliyan;Zellers, Edward T.. And the article was included in IEEE Sensors Journal in 2011.Electric Literature of C6H12BrCl The following contents are mentioned in the article:

Use of electron-beam induced crosslinking (EBIX) to pattern films of thiolate-monolayer-protected gold-nanoparticles (MPNs) on chemiresistor (CR) vapor sensors is described. MPNs with alkyl, cyanoalkyl, phenoxyalkyl, and hydroxyfluoroalkyl thiolate tail groups were patterned on integrated arrays of interdigital electrodes using electron doses of 500-750 μC/cm². The d.c. resistances of solvent cast films of these MPNs decrease and the baseline-normalized changes in resistance to each of five organic vapors increase to different degrees with increasing electron-beam dose. Relative responses patterns from an array of MPN-coated CR sensors for the test vapors change after EBIX patterning and the diversity of responses is diminished, on average, but it is still projected to be sufficient for the discrimination of most of the individual test vapors and binary mixtures Results are rationalized in terms of expected changes in ligand structures and film properties following EBIX patterning using known models of electronic conduction, and vapor-induced changes of conduction, through MPN films. The implications of the results for creating arrays of densely packed MPN-coated CRs as detectors for microanal. systems are considered. This study involved multiple reactions and reactants, such as 1-Bromo-6-chlorohexane (cas: 6294-17-3Electric Literature of C6H12BrCl).

1-Bromo-6-chlorohexane (cas: 6294-17-3) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Electric Literature of C6H12BrCl

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Facile synthesis of carbon-11-labeled arylpiperazinylthioalkyl derivatives as new PET radioligands for imaging of 5-HT_1AR was written by Gao, Mingzhang;Wang, Min;Zheng, Qi-Huang. And the article was included in Applied Radiation and Isotopes in 2012.SDS of cas: 6294-17-3 The following contents are mentioned in the article:

Carbon-11-labeled arylpiperazinylthioalkyl derivatives, 2-((4-(4-(2-[¹¹C]methoxyphenyl)piperazin-1-yl)butyl)thio)benzo[d]oxazole ([¹¹C]5a), 2-((4-(4-(2-[¹¹C]methoxyphenyl)piperazin-1-yl)butyl)thio)-5,7-dimethylbenzo[d]oxazole ([¹¹C]5c), 2-((4-(4-(2-[¹¹C]methoxyphenyl)piperazin-1-yl)butyl)thio)benzo[d]thiazole ([¹¹C]5e), 2-((6-(4-(2-[¹¹C]methoxyphenyl)piperazin-1-yl)hexyl)thio)benzo[d]oxazole ([¹¹C]5g), 2-((6-(4-(2-[¹¹C]methoxyphenyl)piperazin-1-yl)hexyl)thio)-5,7-dimethylbenzo[d]oxazole ([¹¹C]5i), and 2-((6-(4-(2-[¹¹C]methoxyphenyl)piperazin-1-yl)hexyl)thio)benzo[d]thiazole ([¹¹C]5k), were prepared from their corresponding phenol precursors with [¹¹C]CH₃OTf through O-[¹¹C]methylation and isolated by a simplified solid-phase extraction (SPE) method using a Sep-Pak Plus C18 cartridge in 50-60% (n=5) radiochem. yields based on [¹¹C]CO₂ and decay corrected to end of bombardment (EOB). The overall synthesis time from EOB was 23 min, the radiochem. purity was >99%, and the specific activity at end of synthesis (EOS) was 277.5±92.5 GBq/μmol (n=5). This study involved multiple reactions and reactants, such as 1-Bromo-6-chlorohexane (cas: 6294-17-3SDS of cas: 6294-17-3).

1-Bromo-6-chlorohexane (cas: 6294-17-3) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.SDS of cas: 6294-17-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Reporter Protein-Targeted Probes for Magnetic Resonance Imaging was written by Strauch, Renee C.;Mastarone, Daniel J.;Sukerkar, Preeti A.;Song, Ying;Ipsaro, Jonathan J.;Meade, Thomas J.. And the article was included in Journal of the American Chemical Society in 2011.Computed Properties of C6H12BrCl The following contents are mentioned in the article:

Contrast agents for magnetic resonance imaging are frequently employed as exptl. and clin. probes. Drawbacks include low signal sensitivity, fast clearance, and nonspecificity that limit efficacy in exptl. imaging. In order to create a bioresponsive MR contrast agent, a series of four Gd(III) complexes targeted to the HaloTag reporter were designed and synthesized. HaloTag is unique among reporter proteins for its specificity, versatility, and the covalent interaction between substrate and protein. In similar systems, these properties produce prolonged in vivo lifetimes and extended imaging opportunities for contrast agents, longer rotational correlation times, and increases in relaxivity (r₁) upon binding to the HaloTag protein. The authors report a new MR contrast probe, 2CHTGd, which forms a covalent bond with its target protein and results in a dramatic increase in sensitivity. A 6-fold increase in r₁, from 3.8 to 22 mM^-1 s^-1, is observed upon 2CHTGd binding to the target protein. This probe was designed for use with the HaloTag protein system which allows for a variety of substrates (specific for MRI, florescence, or protein purification applications) to be used with the same reporter. This study involved multiple reactions and reactants, such as 1-Bromo-6-chlorohexane (cas: 6294-17-3Computed Properties of C6H12BrCl).

1-Bromo-6-chlorohexane (cas: 6294-17-3) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Computed Properties of C6H12BrCl

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Efficient grafting of redox-active ferrocene polymers from α,ω-diiodoalkanes at cathodically charged glassy carbon was written by Jouikov, Viatcheslav;Simonet, Jacques. And the article was included in Journal of Applied Electrochemistry in 2012.Reference of 6294-17-3 The following contents are mentioned in the article:

α,ω-Dihaloalkanes, when cathodically reduced at glassy carbon (GC), can be immobilized at the electrode surface. The present contribution focuses on the reduction of 1,8-diiodooctane, as model dihalo-substrate, in an aprotic organic solvent containing tetraalkylammonium salts as electrolyte. It is expected that these compounds in contact with GC, polarized at potentials more neg. than -1.7 V vs. Ag/AgCl, partly lead to monoiodoalkyl chain immobilization onto carbon. The process corresponds to the cathodic charge of graphitized and fullerenized zones present in carbon followed by a displacement reaction (analogous to a nucleophilic attack) towards pending C-I functions. This mode of grafting is then applied to the reaction of neg. charged carbon with bis-(ω-iodoalkyl)ferrocenes. Ferrocene is then used as an efficient redox probe. This study aims to point out the formation of a chem. grafted redox polymer at carbon electrodes that permits one to quantify the level of immobilized alkyl chains according to their chain length. Coverage levels were found to be high, and surface concentrations of ferrocene currently >10^-8 mol cm^-2 were reached. Ferrocene layers deposited onto carbon were found to be chem. and electrochem. stable and expected to be suitable for efficient electricity storage. This study involved multiple reactions and reactants, such as 1-Bromo-6-chlorohexane (cas: 6294-17-3Reference of 6294-17-3).

1-Bromo-6-chlorohexane (cas: 6294-17-3) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Reference of 6294-17-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Synthesis of Novel Ultraviolet Absorbers and Preparation and Field Application of Anti-Ultraviolet Aging PBAT/UVA Films was written by Qiao, Run-Meng;Zhao, Chi-Peng;Liu, Jia-Lei;Zhang, Mao-Lin;He, Wen-Qing. And the article was included in Polymers (Basel, Switzerland) in 2022.Application of 6294-17-3 The following contents are mentioned in the article:

Poly-(butylene adipate-co-terephthalate) (PBAT) has become one of the most prevalent biodegradable plastic film materials owing to its good degradability, mech. properties, and processability. However, the degradation time of this material was too fast and the functional period was short, which limited its application. Herein, three new tropolone-based UV absorbers (UVA-1C, UVA-4C and UVA-6C) were rationally designed and blended into PBAT. The PBAT/UVA films that formed were used against UV aging and prolonged the functional period of PBAT film. The three new absorbers were synthesized by bridging two tropolones using three different organic chains with different flexibility. Among them, the UVA-6C showed the strongest UV absorbance at around 238 nm and 320 nm. Consequently, the PBAT/UVA-6C film showed an extended validity period of 240 h in the Xenon lamp aging machine and a prolonged functional period of 8 d during the field application test when compared to pure PBAT. More importantly, a 7.8% increase in the maize yield was obtained under PBAT/UVA-6C film relative to pure PBAT film. Obviously, the novel prepared UVA-6C compound is a good candidate for UV absorption in PBAT, which makes PBAT/UVA-6C film more advantageous over pure PBAT in practical applications as biodegradable agricultural film. This study involved multiple reactions and reactants, such as 1-Bromo-6-chlorohexane (cas: 6294-17-3Application of 6294-17-3).

1-Bromo-6-chlorohexane (cas: 6294-17-3) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkyl chlorides readily react with amines to give substituted amines. Alkyl chlorides are substituted by softer halides such as the iodide in the Finkelstein reaction.Application of 6294-17-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Synthesis of α-cyano and α-sulfonyl cyclic ethers via intramolecular reactions of peroxides with sulfone- and nitrile-stabilized carbanions was written by Horn, Alissa;Dussault, Patrick H.. And the article was included in Journal of Organic Chemistry in 2019.HPLC of Formula: 6294-17-3 The following contents are mentioned in the article:

The intramol. reaction of carbon nucleophiles with oxygen-centered electrophiles has been little explored outside of nucleophilic epoxidation Synthesis of sulfonyl- and cyano-substituted oxacycles via intramol. reaction of sulfone- and nitrile-stabilized carbanions with dialkyl peroxides, triethylsilyl/alkyl peroxides, and monoperoxyacetals were reported. The cyclizations are successfully applied to synthesis of oxetanes, tetrahydrofurans, and tetrahydropyrans but fail for oxepanes. Cyclizations involving the relatively stabilized anion derived from a benzylic nitrile proceed in high yield for a variety of peroxides, including those in which the electrophilic oxygen is formally iso-Bu or neopentyl. Corresponding cyclizations of an alkanenitrile are successful with both dialkyl and alkyl silyl peroxides but demonstrate much greater variability in yield. Reactions of sulfone-containing substrates are successful only with dialkyl peroxides. The success of reactions appears to be strongly influenced by the rate of peroxide decomposition, which appears to be highest for reactions involving poorly stabilized anions. The significant variation in diastereoselectivity observed for different classes of peroxide on a common framework suggests the possibility of substrate-dependent reaction mechanisms. This study involved multiple reactions and reactants, such as 1-Bromo-6-chlorohexane (cas: 6294-17-3HPLC of Formula: 6294-17-3).

1-Bromo-6-chlorohexane (cas: 6294-17-3) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).HPLC of Formula: 6294-17-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Tuning the Properties and Self-Healing Behavior of Ionically Modified Poly(isobutylene-co-isoprene) Rubber was written by Suckow, Marcus;Mordvinkin, Anton;Roy, Manta;Singha, Nikhil K.;Heinrich, Gert;Voit, Brigitte;Saalwaechter, Kay;Boehme, Frank. And the article was included in Macromolecules (Washington, DC, United States) in 2018.Reference of 6294-17-3 The following contents are mentioned in the article:

The focus of this work is on the nature of self-healing of ionically modified rubbers obtained by reaction of brominated poly(isobutylene-co-isoprene) rubber (BIIR) with various alkyl imidazoles such as 1-methylimidazole , 1-Bu imidazole , 1-hexyl imidazole , 1-nonyl imidazole and 1-(6-chloro hexyl)-1H-imidazole . Based on stress-strain and temperature dependent DMA measurements, a structural influence of the introduced ionic imidazolium moieties on the formation of ionic clusters and, as a consequence on the mech. strength and self-healing behavior of the samples could be evidenced. These results are fully supported by a mol.-level assessment of the network structure (crosslink and constraint d.) and the dynamics of the ionic clusters using an advanced proton low-field NMR technique. The results show distinct correlations between the macroscopic behavior and mol. chain dynamics of the modified rubbers. In particular, it is shown that the optimization of material properties with regard to mech. and self-healing behavior is limited by opposing tendencies. Samples with reduced chain dynamics exhibit superior mech. behavior but lack on self-healing behavior. In spite of these limitations, the overall performance of some of our samples including self-healing behavior exceeds distinctly that of other self-healing rubbers described in the literature so far. This study involved multiple reactions and reactants, such as 1-Bromo-6-chlorohexane (cas: 6294-17-3Reference of 6294-17-3).

1-Bromo-6-chlorohexane (cas: 6294-17-3) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Reference of 6294-17-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Direct Reduction of 1-Bromo-6-chlorohexane and 1-Chloro-6-iodohexane at Silver Cathodes in Dimethylformamide was written by Rose, John A.;McGuire, Caitlyn M.;Hansen, Angela M.;Karty, Jonathan A.;Mubarak, Mohammad S.;Peters, Dennis G.. And the article was included in Electrochimica Acta in 2016.Formula: C6H12BrCl The following contents are mentioned in the article:

Cyclic voltammetry and controlled-potential (bulk) electrolyzes were employed to probe the electrochem. reductions of 1-bromo-6-chlorohexane and 1-chloro-6-iodohexane at Ag cathodes in DMF containing 0.050M Bu₄N tetrafluoroborate (TBABF₄). A cyclic voltammogram for reduction of 1-bromo-6-chlorohexane shows a single major irreversible cathodic peak, whereas reduction of 1-chloro-6-iodohexane gives rise to a pair of irreversible cathodic peaks. Controlled-potential (bulk) electrolyzes of 1-bromo-6-chlorohexane at a Ag gauze cathode reveal that the process involves a two-electron cleavage of the C-Br bond to afford 1-chlorohexane as the major product, along with 6-chloro-1-hexene, n-hexane, 1-hexene, and 1,5-hexadiene as minor species. In contrast, bulk electrolyzes of 1-chloro-6-iodohexane indicate that the 1st voltammetric peak corresponds to a 1-electron process, giving a dimer (1,12-dichlorododecane) together with 1-chlorohexane and 6-chloro-1-hexene as well as 1-hexene and 1,5-hexadiene in trace amounts At potentials corresponding to the 2nd cathodic peak, reduction of 1-chloro-6-iodohexane is a mixture of 1- and two-electron steps that yields the same set of products, but in different proportions. Mechanistic schemes probably explain the electrochem. behavior of both 1-bromo-6-chlorohexane and 1-chloro-6-iodohexane. This study involved multiple reactions and reactants, such as 1-Bromo-6-chlorohexane (cas: 6294-17-3Formula: C6H12BrCl).

1-Bromo-6-chlorohexane (cas: 6294-17-3) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Formula: C6H12BrCl

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Design and synthesis of epigallocatechin (EGC) analogs selective to inhibit α-amylase over α-glucosidases via the incorporation of caffeine acid and its derivatives was written by Chen, Wenming;Zhou, Cui;Chen, Jiansheng;Wang, Meizhu;Zhou, Fang;Wang, Chunmei;Zhang, Xu;Zhou, Wen. And the article was included in Bioorganic Chemistry in 2022.Related Products of 6294-17-3 The following contents are mentioned in the article:

Natural products are a promising and underappreciated reservoir for the preferred chem. scaffolds in the search of antidiabetic drugs. In this study twenty-one EGC-based derivatives selective to inhibit human pancreatic α-amylase (HPA), the enzyme at the top of the starch digestion pyramid, have been designed and synthesized in terms of the lead myricetin-caffeic acid conjugate 1 reported ever. We focus on methylation of caffeic acid, length of a liker, a double bond contained in the linker on the inhibition activity and selectivity of EGC-based conjugates. As a result, methylation of caffeic acid and the length of a linker affect significantly the activity and selectivity of EGC-based conjugates, but the effect of a double in caffeic acid is limited. Conjugate 2a-1 having a six-carbon-atom linker fused to EGC and caffeic acid demonstrates the most ponent inhibitory activity to HPA and its selectivity towards HPA over α-glucosidase by far superior to that construct 1. Mol. docking studies reveal that conjugate 2a-1 accommodates well to the active site of HPA with four hydrogen bonds in the form of the preorganization of two moieties EGC and caffeic acid via π-stacking interaction. Collectively, conjugating caffeic acid and EGC with an appropriate linker possibly provides a new strategy for finding the specific HPA inhibitors in the discovery of anti-diabetes mellitus drugs. This study involved multiple reactions and reactants, such as 1-Bromo-6-chlorohexane (cas: 6294-17-3Related Products of 6294-17-3).

1-Bromo-6-chlorohexane (cas: 6294-17-3) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Related Products of 6294-17-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Facile self-crosslinking to improve mechanical and durability of polynorbornene for alkaline anion exchange membranes was written by Huang, Shengmei;He, Xiaohui;Cheng, Changwen;Zhang, Feng;Guo, Yan;Chen, Defu. And the article was included in International Journal of Hydrogen Energy in 2020.Synthetic Route of C6H12BrCl The following contents are mentioned in the article:

Crosslinking is a valid approach to enhance the mech. and durability performance of anion exchange membranes (AEMs). Herein, a facile and effective self-crosslinking strategy, with no need for an addnl. crosslinker or a catalyzer, is proposed. A series of tunable self-crosslinking and ion conduction polynorbornene membranes are designed. The 5-norbornene-2-methylene glycidyl ether (NB-MGE) component which affords self-crosslinking enhances dimensional stability, while the flexible 5-norbornene-2-alkoxy-1-hexyl-3-Me imidazolium chloride (NB-O-Im⁺Cl^–) hydrophilic unit contributes high conductivity The crosslinking significantly decreases the water uptake, and water swelling ratio provides excellent solvent-resistance and enhances the thermal and mech. properties. Addnl., crosslinked rPNB-O-Im-x AEMs exhibit desirable alk. stability. Impressively, the rPNB-O-Im-30 (IEC = 1.377) shows a moderate ion conductivity (61.8 m S cm^-1, 80°C), with a suppressed water absorption and 88.17% initial OH^– conductivity is maintained after treated for 240 h with a 1.0 M NaOH solution at 60°C. Suitably assessed of rPNB-O-Im-30 AEM reveals a 98.4 mW cm^-2 peak power d. reached at a c.d. of about 208 mA cm^-2. The report offers a facile and effectual preparative technique for preparing dimensional and alk. stable AEMs for fuel cells applications. This study involved multiple reactions and reactants, such as 1-Bromo-6-chlorohexane (cas: 6294-17-3Synthetic Route of C6H12BrCl).

1-Bromo-6-chlorohexane (cas: 6294-17-3) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Synthetic Route of C6H12BrCl

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics