Category: 638-07-3

Enantioselective one-pot synthesis of 4H-chromene derivatives catalyzed by a chiral Ni(II) complex was written by Yu, Xuan;Lan, Wenjie;Li, Jiaqi;Bai, Hui;Qin, Zhaohai;Fu, Bin. And the article was included in RSC Advances in 2020.Synthetic Route of C6H9ClO3 The following contents are mentioned in the article:

A Ni(II)-bis(oxazoline) complex and p-TSOH are used to form enantioenriched 4H-chromenes from ortho-quinone methides (o-QMs) and dicarbonyls, providing the desired products in up to 95% ee. The method is compatible with various β-ketoester substrates, and the products obtained could be converted into biol. active 4H-chromene derivatives This study involved multiple reactions and reactants, such as Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3Synthetic Route of C6H9ClO3).

Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Synthetic Route of C6H9ClO3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Access to 6-hydroxy indolizines and related imidazo[1,5-a]pyridines through the S_N2 substitution/condensation/tautomerization cascade process was written by Duan, Guiyun;Liu, Hao;Zhang, Liqing;Yuan, Chunhao;Li, Yongchao;Ge, Yanqing. And the article was included in RSC Advances in 2021.Quality Control of Ethyl 4-chloro-3-oxobutanoate The following contents are mentioned in the article:

A simple and efficient cascade reaction was developed for the construction of hydroxy substituted indolizines I [R¹ = CHO, COMe, I, etc.; R² = H, COOMe, Cl, etc.] and imidazopyridines II [R³ = H, Me; R⁴ = Me, Et] from pyrrole-2-carbaldehydes and com. available 4-halogenated acetoacetic esters. Their optical properties were also evaluated. This study involved multiple reactions and reactants, such as Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3Quality Control of Ethyl 4-chloro-3-oxobutanoate).

Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Quality Control of Ethyl 4-chloro-3-oxobutanoate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Tandem α-Arylation/Cyclization of 4-Haloacetoacetates with Arynes: A Metal-Free Approach toward 4-Aryl-3-(2H)-furanones was written by John, Jubi;Omanakuttan, Vishnu K.;T., Aneeja;Suresh, Cherumuttathu H.;Jones, Peter G.;Hopf, Henning. And the article was included in Journal of Organic Chemistry in 2019.Product Details of 638-07-3 The following contents are mentioned in the article:

An efficacious, metal-free strategy has been developed for the synthesis of 4-aryl-3-(2H)-furanones. The reaction proceeds via the nucleophilic addition of an active methylene compound to the aryne followed by ring closing of the adduct. The reaction proceeds under mild conditions, is applicable for gram-scale synthesis of 4-aryl-3-(2H)-furanones, and is general for a range of substituted arynes and haloacetates. This study involved multiple reactions and reactants, such as Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3Product Details of 638-07-3).

Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Product Details of 638-07-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Solvent-Directed Click Reaction between Active Methylene Compounds and Azido-1,3,5-triazines was written by Yan, Ziqiang;Li, Yuanheng;Ma, Mingming. And the article was included in Organic Letters in 2019.COA of Formula: C6H9ClO3 The following contents are mentioned in the article:

A novel solvent-directed click reaction between active methylene compounds and azido-1,3,5-triazines has been developed. In aqueous solution, the regiospecific trisubstituted 1,2,3-triazole products are quickly synthesized in high yields under mild conditions and easy to sep. without column chromatog. This click reaction is controlled by the protonation of a nitrogen anion intermediate, and the postulated mechanism is substantiated by DFT calculations This study involved multiple reactions and reactants, such as Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3COA of Formula: C6H9ClO3).

Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.COA of Formula: C6H9ClO3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Multicomponent One-pot Synthesis of Oxadiazole Included Pyranopyrazoles as Promising Antioxidant Agents was written by Reddy, Guda Mallikarjuna;Yun Chen, Di;Venkata Subbaiah, Munagapati;Jianyou, Long;Wen, Jet-Chau. And the article was included in Journal of Heterocyclic Chemistry in 2019.Related Products of 638-07-3 The following contents are mentioned in the article:

In this context, a series of oxadiazole included pyranopyrazoles were prepared under eco-friendly synthetic way by using montmorillonite k10 as a catalyst. The final compounds were obtained in good yields. Further, compounds were screened for their antioxidant activity and most of the compounds revealed promising activity. Among all, electron rich-substituted compounds at para position demonstrated higher antioxidant activity than their corresponding ortho-substituted compounds This study involved multiple reactions and reactants, such as Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3Related Products of 638-07-3).

Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Related Products of 638-07-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Furan Synthesis via Triplet Sensitization of Acceptor/Acceptor Diazoalkanes was written by Zhu, Siqi;Li, Fang;Empel, Claire;Jana, Sripati;Pei, Chao;Koenigs, Rene M.. And the article was included in Advanced Synthesis & Catalysis in 2022.Electric Literature of C6H9ClO3 The following contents are mentioned in the article:

Herein, authors report on the photocatalytic reaction of acceptor/acceptor diazoalkanes with terminal alkynes. Exptl. and computational studies suggest the formation of a key triplet carbene intermediate that underwent an addition reaction to the alkyne followed by cyclization to give furan heterocycles (31 to 90% yield). This reaction was studied with a broad range of alkynes and acceptor/acceptor diazoalkanes and now provides access to furans under mild reaction conditions. This study involved multiple reactions and reactants, such as Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3Electric Literature of C6H9ClO3).

Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Electric Literature of C6H9ClO3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Efficient synthesis of some new 1,3,4-thiadiazole and thiazole derivatives via thiosemicarbazone derivatives was written by Raslan, Mohamed Abdelmonem. And the article was included in Heterocycles in 2020.HPLC of Formula: 638-07-3 The following contents are mentioned in the article:

Here reactions of hydrazinecarbodithioate and hydrazinecarbothioamide derivatives with hydrazonoyl chloride derivatives to afford 1,3,4-thiadiazole and thiazole derivatives, resp. was reported. Also, reactions of hydrazinecarbothioamide derivatives with α-halo esters derivatives, di-Et acetylenedicarboxylate and chloroacetonitrile afforded thiazole derivatives The structures of the newly synthesized compounds were established based on its elemental anal. and spectral data. This study involved multiple reactions and reactants, such as Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3HPLC of Formula: 638-07-3).

Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.HPLC of Formula: 638-07-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Improved Practical Synthesis of DY-038, an Oral Available Antiplatelet Agent was written by Cao, Yangzhi;Kong, Deyu;Sun, Lulu;Meng, Xin;Zhang, Yinyong;Guo, Bin;Yang, Yushe. And the article was included in ChemistrySelect in 2021.Safety of Ethyl 4-chloro-3-oxobutanoate The following contents are mentioned in the article:

Herein, a modified and improved chem. synthesis of the lead compound, I with the aim to produce from milligrams to 10g of the pure compound that is necessary for the preclin. studies were described. This novel process was one step shorter and started from cheap materials, achieved a sevenfold of the total yield from 0.7% to 5%. Addnl., it avoided the use of palladium on carbon as well as all of the steps involved simple purifications without chromatog. This study involved multiple reactions and reactants, such as Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3Safety of Ethyl 4-chloro-3-oxobutanoate).

Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Safety of Ethyl 4-chloro-3-oxobutanoate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Total Synthesis of (±)-Leonuketal was written by Grant, Phillip S.;Furkert, Daniel P.;Brimble, Margaret A.. And the article was included in Organic Letters in 2020.Formula: C6H9ClO3 The following contents are mentioned in the article:

Leonuketal is an 8,9-seco-labdane terpenoid with a unique tetracyclic structure, owing to a diversity-generating biosynthetic C-C bond cleavage event. The first total synthesis of leonuketal (I) is reported, featuring a Ti(III)-mediated reductive cyclization of an epoxy nitrile ether, an unusual ring-opening alkyne formation as part of an auxiliary ring strategy, and the previously undescribed Au(I)-catalyzed cyclization of a β-keto(enol)lactone to assemble the core spiroketal motif. This study involved multiple reactions and reactants, such as Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3Formula: C6H9ClO3).

Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Formula: C6H9ClO3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Construction of benzothiophene fused pyrrolidone in water via a catalyst-free process and a mechanism study was written by Shen, Jinhui;Yu, Aimin;Zhang, Lei;Meng, Xiangtai. And the article was included in Green Chemistry in 2020.Synthetic Route of C6H9ClO3 The following contents are mentioned in the article:

A novel three-component domino reaction toward benzothiophene fused pyrrolidone derivatives I [R¹ = H, 5-Br, 5-OMe, etc.; R² = n-Bu, cyclopentyl, Bn, etc.] was developed in an environmentally benign manner. The reaction proceeded well in aqueous media, and delivered the desired products I in high yields with excellent selectivity. D. functional calculations located a multi-step reaction pathway and identified the intramol. nucleophilic addition step to be the rate-determining step. This study involved multiple reactions and reactants, such as Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3Synthetic Route of C6H9ClO3).

Ethyl 4-chloro-3-oxobutanoate (cas: 638-07-3) belongs to organic chlorides. Organic chlorides can cause corrosion in pipelines, valves and condensers, and cause catalyst poisoning. The hydrocarbon processing industry (HPI) and others are affected by damage caused by these substances. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Synthetic Route of C6H9ClO3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics