Category: 6797-79-1

Gautam, Prashant published the artcileAminophosphine Palladium Pincer-Catalyzed Carbonylative Sonogashira and Suzuki-Miyaura Cross-Coupling with High Catalytic Turnovers, Application of 4-Chloro-2-fluoroiodobenzene, the main research area is aryl alkynone ketone preparation; palladium pincer complex catalyst carbonylative Sonogashira Suzuki coupling; iodoarene palladium catalyzed carbonylation Sonogashira Suzuki coupling; kinetics palladium pincer complex catalyzed Sonogashira Suzuki coupling.

In the presence of palladium pincer complex I, aryl iodides underwent carbonylative Sonogashira and Suzuki coupling reactions with aryl alkynes and cyclopropylacetylene and arylboronic acids mediated by K2CO3 in propylene carbonate to yield aryl alkynones and diaryl ketones, resp. Using I, the carbonylative Sonogashira and Suzuki coupling reactions were carried out at 10-4 mol% and 10-6 mol%, resp. Palladium nanoparticles generated from I were characterized.

ACS Omega published new progress about Alkynes, aryl Role: RCT (Reactant), RACT (Reactant or Reagent). 6797-79-1 belongs to class chlorides-buliding-blocks, name is 4-Chloro-2-fluoroiodobenzene, and the molecular formula is C6H3ClFI, Application of 4-Chloro-2-fluoroiodobenzene.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Cao, Qun published the artcileMechanochemical Activation of Zinc and Application to Negishi Cross-Coupling, Computed Properties of 6797-79-1, the main research area is alkyl halide zinc mechanochem aryl halide palladium Negishi coupling; arene alkyl preparation; ball milling; mechanochemistry; organometallic; organozinc; solventless reactions.

A form independent activation of zinc, concomitant generation of organozinc species and engagement in a Negishi cross-coupling reaction via mechanochem. methods is reported. The reported method exhibits a broad substrate scope for both C(sp3)-C(sp2) and C(sp2)-C(sp2) couplings and is tolerant to many important functional groups. The method may offer broad reaching opportunities for the in situ generation organometallic compounds from base metals and their concomitant engagement in synthetic reactions via mechanochem. methods.

Angewandte Chemie, International Edition published new progress about Alkylarenes Role: SPN (Synthetic Preparation), PREP (Preparation). 6797-79-1 belongs to class chlorides-buliding-blocks, name is 4-Chloro-2-fluoroiodobenzene, and the molecular formula is C6H3ClFI, Computed Properties of 6797-79-1.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Dubost, Emmanuelle published the artcileGeneral method for the synthesis of substituted phenanthridin-6(5H)-ones using a KOH-mediated anionic ring closure as the key step, Recommanded Product: 4-Chloro-2-fluoroiodobenzene, the main research area is fluoro arylboronic acid preparation halo arylnitrile Suzuki coupling palladium; fluorobiphenyl carbonitrile preparation anionic ring closure potassium hydroxide microwave; phenanthridinone preparation; microwave irradiation anionic ring closure mediator; potassium hydroxide anionic ring closure mediator; palladium Suzuki cross coupling catalyst.

Substituted phenanthridin-6(5H)-ones were obtained in a two-step procedure involving a Suzuki cross-coupling reaction followed by a KOH-mediated anionic ring closure. The influence of the nature and the position of the substituents on the cyclization step were studied. This methodol. offers a general and practical route to diversely substituted phenanthridin-6(5H)-ones, e.g., I (R = H, F).

Tetrahedron published new progress about Aromatic nitriles Role: RCT (Reactant), RACT (Reactant or Reagent) (halo). 6797-79-1 belongs to class chlorides-buliding-blocks, name is 4-Chloro-2-fluoroiodobenzene, and the molecular formula is C6H3ClFI, Recommanded Product: 4-Chloro-2-fluoroiodobenzene.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Kuzmina, Olesya M. published the artcileLigand-Accelerated Iron- and Cobalt-Catalyzed Cross-Coupling Reactions between N-Heteroaryl Halides and Aryl Magnesium Reagents, COA of Formula: C6H3ClFI, the main research area is biaryl preparation; heteroaryl halide cross coupling arylmagnesium iron cobalt isoquinoline catalyst.

Addition of quinoline or isoquinoline as a ligand dramatically increased the rate and yield of Fe- and Co-catalyzed cross-coupling reactions of heteroaryl chlorides and bromides with arylmagnesium reagents. This new catalytic process extends the scope of such cross-coupling reactions to include complex functional groups and allows the formation of bis(heteroarene)s.

Angewandte Chemie, International Edition published new progress about Aryl halides Role: RCT (Reactant), RACT (Reactant or Reagent) (heteroaryl). 6797-79-1 belongs to class chlorides-buliding-blocks, name is 4-Chloro-2-fluoroiodobenzene, and the molecular formula is C6H3ClFI, COA of Formula: C6H3ClFI.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Pan, Cheng published the artcilePalladium-Catalyzed Site-Selective Benzocylization of Aromatic Acids with o-Fluoro-Substituted Diaryliodonium Salts toward 3,4-Benzocoumarins, COA of Formula: C6H3ClFI, the main research area is benzocoumarin preparation palladium catalyzed site selective benzocyclization; benzocyclization aromatic acid fluoro substituted diaryliodonium salt.

By using 2-fluoro-substituted diaryliodonium salts, a novel benzocylization has been accomplished for the synthesis of 3,4-benzocoumarin derivatives via a cascade of ortho-arylation and defluorination in the presence of palladium catalysts. The reaction exhibits a broad compatibility of readily available aromatic acids with an excellent level of site-selectivity. Mechanistic investigations revealed a unique reactivity of carboxylic acid directed arylation by followed nucleophilic substitution of aromatic fluoride in the present system.

Organic Letters published new progress about Aromatic carboxylic acids Role: RCT (Reactant), RACT (Reactant or Reagent). 6797-79-1 belongs to class chlorides-buliding-blocks, name is 4-Chloro-2-fluoroiodobenzene, and the molecular formula is C6H3ClFI, COA of Formula: C6H3ClFI.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Thorat, Raviraj Ananda published the artcileSynthesis of Chiral-Substituted 2-Aryl-ferrocenes by the Catellani Reaction, Product Details of C6H3ClFI, the main research area is palladium catalyzed three component coupling iodoarene acrylate iodoferrocencarboxamide; chiral aryl ferroceneamide preparation.

A Pd-catalyzed and norbornene-mediated methodol. was developed for the synthesis of chiral 2-aryl-ferroceneamides from chiral 2-iodo-N,N-diisopropylferrocencarboxamide, iodoarenes, and alkenes using a JohnPhos ligand and K carbonate as a base in DMF at 105°. The developed three-component coupling protocol allows the compatibility of electron-withdrawing fluoro, chloro, ester, and nitro and electron-donating Me, methoxy, dimethoxy, benzyl ether-substituted iodo-benzenes, other iodoarenes, such as iodo-naphthalene, heteroarenes, such as iodothiophene, and terminating substrates, such as Me, Et, tert-Bu acrylates, and substituted styrenes with 2-iodo-N,N-diisopropylferrocencarboxamide. Also, the developed three-component Catellani method proceeded with the retention of the configuration of the planar chiral ferrocene, which depends on the role of the participating C-I bond in ferrocene. Consequently, the developed protocol enabled the formation of densely substituted chiral 2-aryl ferroceneamides, exhibiting good to excellent enantioselectivity. The conversion of an ester of the synthesized chiral 2-aryl ferroceneamides also was carried out to further accommodate the easily expendable acid and alc. functionalities.

Journal of Organic Chemistry published new progress about Alkynylation catalysts (Pd complexes). 6797-79-1 belongs to class chlorides-buliding-blocks, name is 4-Chloro-2-fluoroiodobenzene, and the molecular formula is C6H3ClFI, Product Details of C6H3ClFI.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Mikami, Shinichi published the artcileSilica gel-assisted preparation of (bromo)(chloro)(iodo)benzo[b]thiophenes bearing halogen atoms at the 2-, 4-, and 7-positions, Name: 4-Chloro-2-fluoroiodobenzene, the main research area is benzothiophene dihalo trihalo preparation stereoselective silica gel; sulfide adamantyl alkynylaryl halo preparation intramol cyclization silica.

Six types of (bromo)(chloro)(iodo)benzo[b]thiophenes bearing halogen atoms at the 2-, 4-, and 7-positions were prepared from the corresponding 2-(1-adamantylthio)-1,4-dihalo-3-(haloethynyl)benzene derivatives, by treatment with silica gel under thermal conditions. 4,7-Dihalobenzo[b]thiophenes, bearing two different halogen atoms (chlorine, bromine, or iodine), were also prepared from 2-(1-adamantylthio)-3-(ethynyl)-1,4-dihalobenzenes.

Heterocycles published new progress about Aldehydes, halo Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 6797-79-1 belongs to class chlorides-buliding-blocks, name is 4-Chloro-2-fluoroiodobenzene, and the molecular formula is C6H3ClFI, Name: 4-Chloro-2-fluoroiodobenzene.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Wang, Sheng-Li published the artcileSynthesis of biphenylenes and their higher homologues by cyclization of aryne derivatives, Category: chlorides-buliding-blocks, the main research area is halobiaryl cyclization; biphenylene preparation; arynes; biphenyls; cyclizations; lithium; synthetic methods.

This investigation demonstrates that a series of biphenylenes, e.g., I, can be easily prepared from their corresponding halobiphenyls by the cyclization of in situ generated 2′,3′-didehydro-2-lithiobiphenyls at low temperature Two remarkable advantages of this synthetic method include the lack of any need for transition-metal catalysts or reagents in the cyclization, and the ability to obtain C1-functionalized products by treating the reaction intermediate 1-lithiobiphenylene with an electrophilic reagent. π-Extended derivatives, such as benzobiphenylenes, dibenzobiphenylene, linear/angular [3]phenylenes, and biphenyleno[2,3-b]biphenylenes, were synthesized similarly using suitable biaryls or teraryls.

Angewandte Chemie, International Edition published new progress about Aromatic hydrocarbons, arynes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 6797-79-1 belongs to class chlorides-buliding-blocks, name is 4-Chloro-2-fluoroiodobenzene, and the molecular formula is C6H3ClFI, Category: chlorides-buliding-blocks.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chen, Jianxia published the artcileNano palladium catalyzed C(sp3)-H bonds arylation by a transient directing strategy, Product Details of C6H3ClFI, the main research area is supported palladium nanoparticle preparation particle size; methylbenzaldehyde iodobenzene palladium catalyst acetohydrazide promoter arylation; benzylbenzaldehyde preparation.

The first example of heterogeneous palladium catalyzed C(sp3)-H bonds arylation by a transient-ligand-directed strategy was reported. Using supported palladium (metallic state) nanopariticles as catalyst, a wide range of aryl iodides undergo the coupling with various o-methylbenzaldehyde derivatives to assemble a library of highly selective and functionalized o-benzylbenzaldehydes. The stability of the catalyst was easily recovered four runs without significant loss of activity. The XPS anal. of the catalyst before and after reaction indicated that the reaction might be carried out by a catalytic cycle starting with Pd0.

Chinese Chemical Letters published new progress about Arylation. 6797-79-1 belongs to class chlorides-buliding-blocks, name is 4-Chloro-2-fluoroiodobenzene, and the molecular formula is C6H3ClFI, Product Details of C6H3ClFI.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Lakshmi, Parvathi K. published the artcileAn efficient Mn-catalyzed reductive carbonylation of aryl iodides to aryl aldehydes and their benzimidazole and benzoxazoles, Recommanded Product: 4-Chloro-2-fluoroiodobenzene, the main research area is aryl aldehyde benzimidazole benzoxazole preparation; carbon monoxide aryl iodide reductive carbonylation manganese catalyst.

The present study envisaged the development of an efficient protocol of Mn-catalyzed reductive carbonylation of aryl iodides to aryl aldehydes and their corresponding imidazole and oxazole derivatives, by using CO as a carbonyl source, in the presence of hydrosilanes and base [Na2CO3 and NaHCO3 (1:1)] under mild reaction conditions gave a series of aldehydes in good yields. This approach could be extended for further functionalization of aryl aldehydes and to their corresponding benzimidazole and benzoxazole derivatives with high efficiency.

Synthetic Communications published new progress about Aryl iodides Role: RCT (Reactant), RACT (Reactant or Reagent). 6797-79-1 belongs to class chlorides-buliding-blocks, name is 4-Chloro-2-fluoroiodobenzene, and the molecular formula is C6H3ClFI, Recommanded Product: 4-Chloro-2-fluoroiodobenzene.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics