Category: 7080-50-4

Ravn, Anne K. published the artcileCarbon Isotope Labeling Strategy for β-Amino Acid Derivatives via Carbonylation of Azanickellacycles, COA of Formula: C7H13ClNNaO5S, the publication is Journal of the American Chemical Society (2019), 141(30), 11821-11826, database is CAplus and MEDLINE.

A series of 4-membered azametallacycles have been prepared by the oxidative addition of Ni(0) with aziridines. Stoichiometric ¹³C-labeled carbon monoxide could be efficiently incorporated via Ni-C bond insertion to generate air stable and isolable cyclic Ni-acyl complexes. Upon subjection to a range of C-, N-, O-, and S-nucleophiles, ¹³C-labeled β-amino acids and derivatives thereof, as well as β-aminoketones, could be rapidly accessed. The methodol. proved highly adaptable for the synthesis of the antidiabetic drug, sitagliptin, with a single carbon isotope label.

Journal of the American Chemical Society published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, COA of Formula: C7H13ClNNaO5S.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Tesfaldet, Zeriet O. published the artcileSequential injection spectrophotometric determination of trace amounts of iodide by its catalytic effect on the 4,4′-methylenebis(N,N-dimethylaniline)-chloramine-T reaction, Category: chlorides-buliding-blocks, the publication is Talanta (2004), 64(5), 1213-1219, database is CAplus and MEDLINE.

A simple and sensitive sequential injection spectrophotometric procedure is proposed for the determination of trace amounts of iodide in pharmaceutical preparations The method was based on the catalytic effect of iodide on the (tetra base) 4,4′-methylene bis(N,N-dimethylaniline)chloramine-T reaction in acidic solution The method involves a sequential aspiration of 255 μl sample/standard followed by 170 μl tetra base and then 128 μl chloramine-T solutions into a carrier stream to be stacked inside a holding coil and flow reversed through a reaction coil towards a detector. The resulting colored compound was measured at 600 nm using an UV/Vis-spectrophotometer. All the parameters that affected the reaction were evaluated and the calibration curve was linear over a range of 0.1-6.0 μg l^-1 of iodide concentration with detection limit of 0.05 μg l^-1. A sample throughput of 80 samples per h and relative standard deviation of less than 2.0% was achieved. The method was successfully applied for the determination of iodide in three different samples (tablets).

Talanta published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C3H12Cl2N2, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Spielmann, Kim published the artcileDiastereoselective Palladium-Catalyzed (3 + 2)-Cycloadditions from Cyclic Imines and Vinyl Aziridines, Computed Properties of 7080-50-4, the publication is Organic Letters (2018), 20(5), 1444-1447, database is CAplus and MEDLINE.

The synthesis of fused imidazolidines, e.g., I (x-ray single crystal structure shown), via two N-C bond-forming sequences has been developed. The transformation goes through a (3 + 2)-cycloaddition reaction in the presence of catalytic amounts of palladium by combining several vinyl aziridines and cyclic N-sulfonyl imines. Interestingly, the use of LiCl as additive allowed the improvement of diastereoselectivities when less encumbered substrates were used. The imidazolidine derivatives that bear aminal cores are isolated in high yields (15 examples, up to 96% yield) and diastereoselectivities (up to >20:1).

Organic Letters published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C8H19NO2, Computed Properties of 7080-50-4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Shi, Peng published the artcileVisible Light-Promoted Synthesis of β-Keto Sulfoximines from N-Tosyl-Protected Sulfoximidoyl Chlorides, Related Products of chlorides-buliding-blocks, the publication is Journal of Organic Chemistry, database is CAplus and MEDLINE.

Under visible light, N-tosyl-protected sulfoximidoyl chlorides RSO(NTs)Cl (R = 4-CH₃C₆H₄, 4-CH₃OC₆H₅, 1-naphthyl, etc.) react with aryl alkynes R¹C₆H₄CC (R¹ = 4-Cl, 3-Br, 3-Me, etc.) to give β-keto sulfoximines I. The reaction is characterized by a high functional group tolerance and good yields. It can be improved by the presence of a ruthenium photocatalyst. Air is the source of the ketonic oxygen in the products.

Journal of Organic Chemistry published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H10BNO4S, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Shi, Peng published the artcileRegio- and Stereoselective Chloro Sulfoximidations of Terminal Aryl Alkynes Enabled by Copper Catalysis and Visible Light, Recommanded Product: Sodium chloro(tosyl)amide trihydrate, the publication is Advanced Synthesis & Catalysis (2021), 363(10), 2552-2556, database is CAplus.

By visible-light photoredox catalysis with copper complexes, sulfoximidoyl chlorides add to terminal aryl alkynes to gave the corresponding (E)-β-chlorovinyl sulfoximines I [R = 2-thienyl, Ph, 2-naphthyl, etc.; R¹ = n-Pr, Ph, 4-MeC₆H₄, etc.] with exclusive regio- and stereoselectivities in high yields. Two representative products I [R = 4-BrC₆H₄, 4-t-BuC₆H₄; R¹ = Ph] had been characterized by X-ray crystal structure anal. Radicals appear was decisive intermediates. As demonstrated by two subsequent reactions, the products could be derivatized.

Advanced Synthesis & Catalysis published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C9H21NO3, Recommanded Product: Sodium chloro(tosyl)amide trihydrate.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Sanli, Nazmiye Ozlem published the artcileEffects of material type on biofilm response to an oxidising biocide in a laboratory-scale cooling tower system: Effect of material type in response to biocide, Name: Sodium chloro(tosyl)amide trihydrate, the publication is Johnson Matthey Technology Review (2021), 65(2), 161-169, database is CAplus.

Biofilms in industrial cooling tower systems are an important problem. The importance of the surface material in the response to an oxidising biocide (chloramine T trihydrate) was substantiated in our study. Polyvinyl chloride (PVC) cooling tower fill material, stainless steel cooling tower construction material and glass surfaces were compared by evaluating the bacterial loads on materials before and after biocidal treatment. The greatest logarithmic decrease in bacterial load was recorded as >3 log for glass after the first two months and for PVC after the second month. Actively respiring bacterial counts and ATP (ATP) measurements showed that there was no significant difference in the sensitivity of biofilmassocd. cells to the biocide on the different surfaces. In addition, the effect of the biocidal treatment decreased with increasing biofilm age, regardless of the material.

Johnson Matthey Technology Review published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Name: Sodium chloro(tosyl)amide trihydrate.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Sanli, Nazmiye Ozlem published the artcileEvaluation of biocidal efficacy of Chloramine T trihydrate on planktonic and sessile bacteria in a model cooling tower water system, Name: Sodium chloro(tosyl)amide trihydrate, the publication is Water Science and Technology (2019), 79(3), 526-536, database is CAplus and MEDLINE.

In the current study, model cooling tower system was exptl. seeded with Legionella pneumophila and real industrial cooling tower (CT) water has been run at the closest to full-scale system operating conditions. The water/biofilm samples were taken from the model system monthly, and the effectiveness of the different concentrations of Chloramine T trihydrate biocide was evaluated in terms of its ability to control both planktonic/sessile microbial populations. Although Chloramine T is a recommended com. formulation for disinfecting CTs, there is a lack of published data on the efficacy of this compound against both planktonic and sessile populations in the cooling tower. Biocide response in both sessile/planktonic bacteria counts varied according to months. Tested biocide concentrations provided the clean tower conditions by reducing the concentration of heterotrophic plate count (HPC) below <104 cfu mL-1, L. pneumophila <10 cfu mL-1 and of ATP (ATP) values <300 relative light units (RLU), after 1, 3 and 24 h of exposure, during a 6-mo period. There were no statistically significant differences in efficacy between concentrations in terms of reduction in the number of bacteria, decrease in ATP value and viability. The results revealed that Chloramine T can effectively control biofouling in cooling systems according to the limit values of the successful control program.

Water Science and Technology published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Name: Sodium chloro(tosyl)amide trihydrate.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Liu, Renxiang published the artcileModified and Scalable Synthesis of N-Tosyl-4-Chlorobenzenesulfonimidoyl Fluoride (SulfoxFluor): Direct Imidation of Sulfinyl Chlorides with Chloramine-T Trihydrate, Category: chlorides-buliding-blocks, the publication is Organic Process Research & Development (2022), 26(2), 380-386, database is CAplus.

A general and practical method for the preparation of N-Tosyl-4-chlorobenzenesulfonimidoyl fluoride (SulfoxFluor) and its adaptation to a large scale was disclosed. Starting from readily available 4-chlorobenzenesulfonyl chloride, chloramine-T trihydrate and potassium fluoride, SulfoxFluor was prepared on a hectogram scale in 63% overall yield with simple purification techniques. The use of chloramine-T trihydrate (instead of anhydrous chloramine-T) was a significant improvement over previous work, which streamlined the process and avoided the risk of explosion during drying or heating. This research not only established a reliable method for the scale-up synthesis of SulfoxFluor but also provided an insight into the imidation of sulfinyl chlorides with chloramine-T in the presence of water.

Organic Process Research & Development published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Qian, Hui published the artcileOrganocatalytic Enantio- and Diastereoselective Synthesis of 1,2-Dihydronaphthalenes from Isobenzopyrylium Ions, Quality Control of 7080-50-4, the publication is Journal of the American Chemical Society (2015), 137(2), 560-563, database is CAplus and MEDLINE.

A highly efficient asym. synthesis of dihydronaphthalenes I [R¹ = H, 7-Me, 6-F, etc; R² = Ph, 4-Me-C₆H₄, 4-OMe-C₆H₄, etc; Ar = Ph, 4-OMe-C₆H₄, 4-Me-C₆H₄, etc.] is disclosed. The process represents a new addition to the limited asym. reactions of isobenzopyryliums, a family of versatile 10π-electron aromatic species. Excellent asym. induction is achieved for the first time without an anchoring group in the 4-position or a metal catalyst, both of which were required previously in these reactions. The success is attributed to the unusual chiral counteranion (meanwhile also the nucleophile) generated in situ from the chiral phosphate and the boronic acid as well as the leaving group. Preliminary control experiments provided important insight into the reaction mechanism.

Journal of the American Chemical Society published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Quality Control of 7080-50-4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Wang, Yan-Guang published the artcileParallel synthesis of pyrazolines on soluble polymer support, Computed Properties of 7080-50-4, the publication is Synlett (2003), 1467-1468, database is CAplus.

An efficient parallel liquid-phase synthesis of pyrazolines I (R¹ = H, Me; R² = Ph, 4-MeOC₆H₄, 2-furyl; R³ = Ph, 4-MeC₆H₄, 4-FC₆H₄) has been developed. The one-pot three-component reaction of polyethylene glycol (PEG)-supported acrylate, arylaldehydes, and aryl hydrazines, in the presence of chloramine-T in methanol, gave the corresponding PEG-supported pyrazolines. Cleavage from the support under mild conditions afforded pyrazolines I in good yields and high purities.

Synlett published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C5H5NO3S, Computed Properties of 7080-50-4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics