Luo, Zhan-gang’s team published research in Zhongguo Weisheng Jianyan Zazhi in 22 | CAS: 7080-50-4

Zhongguo Weisheng Jianyan Zazhi published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Synthetic Route of 7080-50-4.

Luo, Zhan-gang published the artcileDetermination of total cyanide in water by flow injection, Synthetic Route of 7080-50-4, the publication is Zhongguo Weisheng Jianyan Zazhi (2012), 22(7), 1510-1511, database is CAplus.

The objective of this paper is to establish a method for detection of total cyanide in water by flow injection. In this study, FSIV + flow injection was selected. The sample was decomposed in an acidic medium by UV-light. The hydrogen cyanide was separated by online distillation at 160 °C. The hydrogen cyanide reacted with chloramine T trihydrate while pH â‰?8 to produce hydrogen chloride, which reacted with pyridine-barbituric acid to give a red complex for detection at wavelength of 570 nm. Results show that this method had a good correlation (r>0.9990, n=6), the RSD% of standards and samples were both less than 5%. The spike recovery rate in samples was between 87% and 105% and the method detection limit was 0.97 μg/L. It was concluded that the method is rapid, accurate, highly sensitive and the results are satisfactory.

Zhongguo Weisheng Jianyan Zazhi published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Synthetic Route of 7080-50-4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Kok, Germaine Pui Yann’s team published research in Organic Letters in 20 | CAS: 7080-50-4

Organic Letters published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Name: Sodium chloro(tosyl)amide trihydrate.

Kok, Germaine Pui Yann published the artcileCu-Catalyzed [3 + 3] Cycloaddition of Isocyanoacetates with Aziridines and Stereoselective Access to α,γ-Diamino Acids, Name: Sodium chloro(tosyl)amide trihydrate, the publication is Organic Letters (2018), 20(17), 5112-5115, database is CAplus and MEDLINE.

We report herein an efficient Cu-catalyzed formal [3 + 3] cycloaddition of isocyanoacetates with readily available aziridines of different substitution patterns, which provides a practical access to valuable 1,4,5,6-tetrahydropyrimidine derivatives In particular, the use of enantiopure aziridines delivers disubstituted tetrahydropyrimidines bearing a 1,3-diamino unit in good yields as a single stereoisomer (>20:1 dr, > 99% ee). The heterocyclic products can also be easily converted to synthetically useful amino alc. derivatives or α,γ-diamino acids.

Organic Letters published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Name: Sodium chloro(tosyl)amide trihydrate.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Wang, Guan-Wu’s team published research in Advanced Synthesis & Catalysis in 349 | CAS: 7080-50-4

Advanced Synthesis & Catalysis published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C10H10O2, Name: Sodium chloro(tosyl)amide trihydrate.

Wang, Guan-Wu published the artcileMechanochemical aminochlorination of electron-deficient olefins with chloramine-T promoted by (diacetoxyiodo)benzene, Name: Sodium chloro(tosyl)amide trihydrate, the publication is Advanced Synthesis & Catalysis (2007), 349(11+12), 1977-1982, database is CAplus.

A direct and convenient procedure for the solvent-free mechanochem. aminochlorination of electron-deficient olefins promoted by (diacetoxyiodo)benzene [PhI(OAc)2] was described using com. available and cheap chloramine-T as a nitrogen and chlorine source. The vicinal chloramine derivatives were obtained in high regio- and stereoselectivity with good yields. PhI(OAc)2 was superior to metal salts for the aminochlorination of electron-deficient olefins.

Advanced Synthesis & Catalysis published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C10H10O2, Name: Sodium chloro(tosyl)amide trihydrate.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Apgar, James M.’s team published research in Bioorganic & Medicinal Chemistry Letters in 30 | CAS: 7080-50-4

Bioorganic & Medicinal Chemistry Letters published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Synthetic Route of 7080-50-4.

Apgar, James M. published the artcileMK-5204: An orally active β-1,3-glucan synthesis inhibitor, Synthetic Route of 7080-50-4, the publication is Bioorganic & Medicinal Chemistry Letters (2020), 30(17), 127357, database is CAplus and MEDLINE.

Our previously reported efforts to produce an orally active β-1,3-glucan synthesis inhibitor through the semi-synthetic modification of enfumafungin focused on replacing the C2 acetoxy moiety with an aminotetrazole and the C3 glycoside with a N,N-dimethylaminoether moiety. This work details further optimization of the C2 heterocyclic substituent, which identified 3-carboxamide-1,2,4-triazole as a replacement for the aminotetrazole with comparable antifungal activity. Alkylation of either the carboxamidetriazole at C2 or the aminoether at C3 failed to significantly improve oral efficacy. However, replacement of the iso-Pr α-amino substituent with a t-Bu, improved oral exposure while maintaining antifungal activity. These two structural modifications produced MK-5204, which demonstrated broad spectrum activity against Candida species and robust oral efficacy in a murine model of disseminated Candidiasis without the N-dealkylation liability observed for the previous lead.

Bioorganic & Medicinal Chemistry Letters published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Synthetic Route of 7080-50-4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Zhou, Li’s team published research in European Polymer Journal in 140 | CAS: 7080-50-4

European Polymer Journal published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C5H6BNO2, Formula: C7H13ClNNaO5S.

Zhou, Li published the artcileN-heterocyclic olefins catalyzed ring-opening polymerization of N-tosyl aziridines, Formula: C7H13ClNNaO5S, the publication is European Polymer Journal (2020), 110046, database is CAplus.

A N-heterocyclic olefins (NHOs) catalyzed ring-opening polymerization of N-tosyl aziridines has been developed under metal-free and mild conditions. The NHO serves as a highly efficient and versatile organocatalyst for the synthesis of linear poly(aziridine)s, delivering the corresponding polymers with high chain-end fidelity, controlled mol. weights (up to 83 kg/mol) and narrow mol. weight distributions (ETH = 1.10-1.16). Based on MALDI-TOF MS and 1H NMR spectroscopies’ results, an anionic ring-opening polymerization (AROP) mechanism has been proposed.

European Polymer Journal published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C5H6BNO2, Formula: C7H13ClNNaO5S.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Wu, Xue-Liang’s team published research in Journal of Organic Chemistry in 72 | CAS: 7080-50-4

Journal of Organic Chemistry published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C3H5BN2O2, HPLC of Formula: 7080-50-4.

Wu, Xue-Liang published the artcileAminochlorination in Water: First Bronsted Acid-Promoted Synthesis of Vicinal Chloramines, HPLC of Formula: 7080-50-4, the publication is Journal of Organic Chemistry (2007), 72(24), 9398-9401, database is CAplus and MEDLINE.

A practical and scalable route for the regioselective and diastereoselective synthesis of vicinal chloro amines from electron-deficient olefins and Chloramine-T promoted by Bronsted acids in water has been realized for the first time. This novel protocol is efficient, mild, ecofriendly, and broadly applicable for the aminochlorination of various electron-deficient olefins including α,β-unsaturated ketones, cinnamate and cinnamamide. Water represents as a privileged solvent for the aminochlorination reaction in the authors’ reaction system.

Journal of Organic Chemistry published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C3H5BN2O2, HPLC of Formula: 7080-50-4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Liu, Jiawei’s team published research in ACS Catalysis in 10 | CAS: 7080-50-4

ACS Catalysis published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Product Details of C7H13ClNNaO5S.

Liu, Jiawei published the artcileZinc-Catalyzed Hydroxyl-Directed Regioselective Ring Opening of Aziridines in SN2 Reaction Pathway, Product Details of C7H13ClNNaO5S, the publication is ACS Catalysis (2020), 10(1), 556-561, database is CAplus.

In this protocol, a zinc-catalyzed catalytic regioselective ring opening of electronically and sterically unbiased 2,3-aziridinyl alcs. has been accomplished. The directing effect of the hydroxyl moiety enables the selective nucleophilic attack to the C-3 position of 2,3-aziridinyl alcs. with various aromatic amines and thiophenols as nucleophiles. This operationally simple reaction provides convenient access to a variety of amino alcs. and hydroxyl sulfides in excellent regiocontrol. Moreover, simple derivatization of the ring opening product establishes a general strategy to approach internal vicinal diamines in regioselective and diastereomerically pure form.

ACS Catalysis published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Product Details of C7H13ClNNaO5S.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Herranz, Eugenio’s team published research in Organic Syntheses in 61 | CAS: 7080-50-4

Organic Syntheses published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, HPLC of Formula: 7080-50-4.

Herranz, Eugenio published the artcileOsmium-catalyzed vicinal hydroxyamination of olefins by chloramine-T: cis-2-(p-toluenesulfonamido)cyclohexanol and 2-methyl-3-(p-toluenesulfonamido)-2-pentanol. [Benzenesulfonamide, N-(2-hydroxycyclohexyl)-4-methyl-, cis-], HPLC of Formula: 7080-50-4, the publication is Organic Syntheses (1983), 85-93, database is CAplus.

Addition of p-MeC6H4SO2NClNa (I) to Me2C:CHEt in the presence of OsO4 gave Me2C(OH)CH(NHSO2C6H4Me-p)Et. Similarly, addition of I to cyclohexene gave 75-81.2% II.

Organic Syntheses published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, HPLC of Formula: 7080-50-4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Wambaugh, John F.’s team published research in Environmental Science & Technology in 47 | CAS: 7080-50-4

Environmental Science & Technology published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C5H10BNO2, Computed Properties of 7080-50-4.

Wambaugh, John F. published the artcileHigh-Throughput Models for Exposure-Based Chemical Prioritization in the ExpoCast Project, Computed Properties of 7080-50-4, the publication is Environmental Science & Technology (2013), 47(15), 8479-8488, database is CAplus and MEDLINE.

USEPA must characterize potential risks to human health and the environment associated with manufacture and use of thousands of chems. High-throughput screening (HTS) for biol. activity allows the ToxCast research program to prioritize chem. inventories for potential hazard. Similar capabilities to estimate exposure potential would support rapid, risk-based prioritization for chems. with limited information; this work proposes a framework for high-throughput exposure assessment. To demonstrate its application, an anal. was conducted to predict human exposure potential for chems. and estimate prediction uncertainty by comparison with biomonitoring data. In total, 1936 chems. were evaluated using far-field mass balance human exposure models (USEtox, RAIDAR) and an indicator for indoor and/or consumer use. These predictions were compared to exposures inferred by Bayesian anal. of urine concentrations for 82 chems. reported in the National Health and Nutrition Examination Survey (NHANES). Joint regression of all factors provided a calibrated consensus prediction, the variance of which served as an empirical determination of uncertainty to prioritize absolute exposure potential. Information on use was most predictive; generally, chems. above the limit of detection in NHANES had consumer/indoor use. Coupled with hazard HTS, exposure HTS can assign risk earlier in decision processes. High-priority chems. become targets for further data collection.

Environmental Science & Technology published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C5H10BNO2, Computed Properties of 7080-50-4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Padmaja, A.’s team published research in European Journal of Medicinal Chemistry in 46 | CAS: 7080-50-4

European Journal of Medicinal Chemistry published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Product Details of C7H13ClNNaO5S.

Padmaja, A. published the artcileSynthesis and antioxidant activity of oxazolyl/thiazolylsulfonylmethyl pyrazoles and isoxazoles, Product Details of C7H13ClNNaO5S, the publication is European Journal of Medicinal Chemistry (2011), 46(10), 5034-5038, database is CAplus and MEDLINE.

A new class of oxazolyl/thiazolylsulfonylmethyl pyrazoles I(X= O, S, R = H, Me, Cl) and II(X= O, S, R1 = R2 = H, cl; X= O, S, R1 = Me, R2 = MeO) and isoxazoles III(X= O, S, R1 = R2 = H, cl; X= O, S, R1 = Me, R2 = MeO) were prepared from the synthetically vulnerable intermediate E-styrylsulfonylacetic acid Me ester and studied their antioxidant activity.

European Journal of Medicinal Chemistry published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Product Details of C7H13ClNNaO5S.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics