Category: 7116-36-1

Sim, T. B.; Yoon, N. M. published an article in Synlett. The title of the article was 《Selective reduction of α,β-unsaturated acid derivatives using borohydride exchange resin-CuSO4 in methanol》.Name: Ethyl 3-(4-chlorophenyl)propanoate The author mentioned the following in the article:

Borohydride exchange resin-copper sulfate in methanol readily reduces α,β-unsaturated esters, amides, and nitriles quant. to the corresponding saturated acid derivative at room temperature In the experiment, the researchers used Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Name: Ethyl 3-(4-chlorophenyl)propanoate)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Name: Ethyl 3-(4-chlorophenyl)propanoate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Novel ZnX2-modulated Pd/C and Pt/C catalysts for chemoselective hydrogenation and hydrogenolysis of halogen-substituted nitroarenes, alkenes, benzyl ethers, and aromatic ketones》 was published in Synthesis in 2003. These research results belong to Wu, George; Huang, Mingsheng; Richards, Monique; Poirier, Marc; Wen, Xin; Draper, Richard W.. SDS of cas: 7116-36-1 The article mentions the following:

Several ZnX2-modulated Pd/C and Pt/C catalysts were developed to chemoselectively hydrogenate halogen-substituted nitroarenes, alkenes, benzyl ethers, and aromatic ketones. In addition to this study using Ethyl 3-(4-chlorophenyl)propanoate, there are many other studies that have used Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1SDS of cas: 7116-36-1) was used in this study.

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties.SDS of cas: 7116-36-1 Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Quality Control of Ethyl 3-(4-chlorophenyl)propanoateOn October 10, 2005 ,《Chemoselective Heck arylation of acrolein diethyl acetal catalyzed by an oxime-derived palladacycle》 was published in Tetrahedron. The article was written by Najera, Carmen; Botella, Luis. The article contains the following contents:

A dimeric 4-hydroxyacetophenone oxime-derived palladacycle has been used as a very efficient precatalyst for the chemoselective arylation of CH2:CH(OEt)2 (I) to give either cinnamaldehyde derivatives or 3-arylpropanoate esters by proper choice of the reaction conditions. The synthesis of cinnamaldehyde derivatives can be performed by Heck reaction of I with haloarenes in Me2NAc using K2CO3 as base at 120 °C and Bu4N OAc and KCl as additives, followed by acid workup. In the case of 3-arylpropanoate esters the arylation of I with iodoarenes can be performed at 90 °C in aqueous DMA using (dicyclohexyl)methylamine as base, whereas for bromoarenes the reaction has to be performed at 120 °C using Bu4NBr as additive. Alternatively, this process can be performed under microwave irradiation These couplings take place in good yields and with lower catalyst loading than with palladium(II) acetate as well as in shorter reaction times and with lower excess of I. In the part of experimental materials, we found many familiar compounds, such as Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Quality Control of Ethyl 3-(4-chlorophenyl)propanoate)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. Many organochlorine compounds have been isolated from natural sources ranging from bacteria to humans. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Quality Control of Ethyl 3-(4-chlorophenyl)propanoate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Name: Ethyl 3-(4-chlorophenyl)propanoateOn November 30, 2019 ,《An enzymatic platform for the asymmetric amination of primary, secondary and tertiary C(sp3)-H bonds》 appeared in Nature Chemistry. The author of the article were Yang, Yang; Cho, Inha; Qi, Xiaotian; Liu, Peng; Arnold, Frances H.. The article conveys some information:

The ability to selectively functionalize ubiquitous C-H bonds streamlines the construction of complex mol. architectures from easily available precursors. Here we report enzyme catalysts derived from a cytochrome P 450 that use a nitrene transfer mechanism for the enantioselective amination of primary, secondary and tertiary C(sp3)-H bonds. These fully genetically encoded enzymes are produced and function in bacteria, where they can be optimized by directed evolution for a broad spectrum of enantioselective C(sp3)-H amination reactions. These catalysts can aminate a variety of benzylic, allylic and aliphatic C-H bonds in excellent enantioselectivity with access to either antipode of product. Enantioselective amination of primary C(sp3)-H bonds in substrates that bear geminal di-Me substituents furnished chiral amines that feature a quaternary stereocenter. Moreover, these enzymes enabled the enantioconvergent transformation of racemic substrates that possess a tertiary C(sp3)-H bond to afford products that bear a tetrasubstituted stereocenter, a process that has eluded small-mol. catalysts. Further engineering allowed for the enantioselective construction of methyl-Et stereocenters, which is notoriously challenging in asym. catalysis. In the part of experimental materials, we found many familiar compounds, such as Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Name: Ethyl 3-(4-chlorophenyl)propanoate)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. Many organochlorine compounds have been isolated from natural sources ranging from bacteria to humans. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Name: Ethyl 3-(4-chlorophenyl)propanoate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Formula: C11H13ClO2On June 2, 2017, Zhang, Hongwei; Muniz, Kilian published an article in ACS Catalysis. The article was 《Selective Piperidine Synthesis Exploiting Iodine-Catalyzed Csp3-H Amination under Visible Light》. The article mentions the following:

A route to selective piperidine formation through intramol. catalytic Csp3-H amination is described. This hydrocarbon amination reaction employs a homogeneous iodine catalyst derived from halogen coordination between mol. iodine and a terminal oxidant. It relies on visible light initiation and proceeds within two catalytic cycles that comprise a radical C-H functionalization and an iodine-catalyzed C-N bond formation. The protocol is demonstrated for a total of 30 applications. In addition to this study using Ethyl 3-(4-chlorophenyl)propanoate, there are many other studies that have used Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Formula: C11H13ClO2) was used in this study.

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties.Formula: C11H13ClO2 Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Sugimura, Rie; Qiao, Kun; Tomida, Daisuke; Kume, Yohei; Yokoyama, Chiaki published an article in Chemistry Letters. The title of the article was 《Immobilization of palladium acetate on ionic liquid copolymerized polystyrene: a way to eliminate inhibiting effect of imidazolium chloride and enhance catalytic performance》.Product Details of 7116-36-1 The author mentioned the following in the article:

Immobilization of palladium acetate on a novel polymeric support that is prepared by copolymerization of 3-butyl-1-vinylimidazolium chloride with styrene is demonstrated to be an effective way to eliminate inhibiting effect of imidazolium chloride and enhance catalytic performance. In the part of experimental materials, we found many familiar compounds, such as Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Product Details of 7116-36-1)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. Product Details of 7116-36-1 However, the extent of chlorination is difficult to control. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Kosal, Andrew D.; Ashfeld, Brandon L. published an article in Organic Letters. The title of the article was 《Titanocene-catalyzed conjugate reduction of α,β-unsaturated carbonyl derivatives》.Electric Literature of C11H13ClO2 The author mentioned the following in the article:

A titanocene-catalyzed conjugate reduction of α,β-unsaturated carbonyl derivatives has been developed. A series of carbonyl compounds including aldehydes, ketones, esters, and amides proved viable in the reduction process providing an efficient, chemoselective method for the catalytic reduction of unsaturated carbonyl derivatives After reading the article, we found that the author used Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Electric Literature of C11H13ClO2)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. Electric Literature of C11H13ClO2 The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The author of 《A novel method for carbon-carbon bond formation. Palladium-catalyzed cross-coupling reaction of phenyl fluoroalkanesulfonates with organozinc reagents》 were Chen, Qingyun; He, Yabo. And the article was published in Tetrahedron Letters in 1987. Safety of Ethyl 3-(4-chlorophenyl)propanoate The author mentioned the following in the article:

Cross-coupling reaction of Ph fluoroalkanesulfonates with organozinc reagents in the presence of palladium gives the corresponding alkylbenzenes in good yields. Thus, PhOSO2CF3 and MeOCH2CCZnCl in DMF-THF in the presence of (Ph3P)4Pd at 70° for 12 h gives 67% PhCCCH2OMe. In the experimental materials used by the author, we found Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Safety of Ethyl 3-(4-chlorophenyl)propanoate)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties.Safety of Ethyl 3-(4-chlorophenyl)propanoate Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The author of 《Anodic benzylic C(sp3)-H amination: unified access to pyrrolidines and piperidines》 were Herold, Sebastian; Bafaluy, Daniel; Muniz, Kilian. And the article was published in Green Chemistry in 2018. Computed Properties of C11H13ClO2 The author mentioned the following in the article:

An electrochem. aliphatic C-H amination strategy was developed to access the important heterocyclic motifs of pyrrolidines and piperidines within a uniform reaction protocol. The mechanism of this unprecedented C-H amination strategy involved anodic C-H activation to generate a benzylic cation, which was efficiently trapped by a nitrogen nucleophile. The applicability of the process was demonstrated for 40 examples comprising both 5- and 6-membered ring formations. The experimental part of the paper was very detailed, including the reaction process of Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Computed Properties of C11H13ClO2)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. Many organochlorine compounds have been isolated from natural sources ranging from bacteria to humans. Computed Properties of C11H13ClO2 Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

In 2003,Organic Syntheses included an article by Jensen, Anne Eeg; Kneisel, Florian; Knochel, Paul. Product Details of 7116-36-1. The article was titled 《Ethyl 3-(p-cyanophenyl)propionate from ethyl 3-iodopropionate and p-cyanophenylzinc bromide》. The information in the text is summarized as follows:

The reaction of bromo(4-cyanophenyl)zinc with 3-iodopropanoic acid Et ester in the presence of bis(acetylacetonato)nickel and 4-fluorostyrene gave the title compound, 4-cyanobenzenepropanoic acid Et ester. The role of 4-fluorostyrene is to reduce the electron d. of an [(aryl)nickel(alkyl)] intermediate by coordinating the nickel center and consequently favoring a reductive elimination leading to an aryl-alkyl product. The reaction represents a cross-coupling between an aryl organometallic reactant and an alkyl iodide derivative The nickel-catalyzed cross-coupling of other arylzinc bromides with alkyl iodides in the presence of 4-(trifluoromethyl)styrene was also reported. Arylzinc bromides can be prepared from aryllithium or arylmagnesium precursors. The experimental process involved the reaction of Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Product Details of 7116-36-1)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties.Product Details of 7116-36-1 Organochlorine compounds have wide use in many applications, though some are of profound environmental concern, with TCDD being one of the most notorious.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics