Category: 7116-36-1

《Biocatalytic hydrolysis of various esters using Baker’s yeast under neutral conditions without sucrose》 was written by Noguchi, Takuya; Satoh, Shin; Daitoku, Hideyuki; Kawashima, Yuya; Imai, Nobuyuki. Quality Control of Ethyl 3-(4-chlorophenyl)propanoate And the article was included in Tetrahedron Letters on August 17 ,2022. The article conveys some information:

It was found that biocatalytic hydrolysis of various esters using Baker’s yeast proceeds efficiently under neutral conditions without sucrose. Hydrolysis of Et, Me, Pr, iso-Pr, benzyl, allyl, prenyl, and vinyl esters of 3-phenylpropanoic acid using Baker’s yeast gave easily 3-phenylpropanoic acid in 52-86% yields. In contrast, Baker’s yeast did not hydrolyze the rigid structural esters such as cinnamyl and Ph 3-phenylpropanoates. Then, Baker’s yeast hydrolyzed various Et esters of 3-arylpropanoic acids, 4-phenylbutanoic acid, and fatty acids to afford the corresponding acids in 29-85% yields. In the part of experimental materials, we found many familiar compounds, such as Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Quality Control of Ethyl 3-(4-chlorophenyl)propanoate)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. Quality Control of Ethyl 3-(4-chlorophenyl)propanoate However, the extent of chlorination is difficult to control. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

In 1984,Organic Syntheses included an article by Citterio, Attilio. Name: Ethyl 3-(4-chlorophenyl)propanoate. The article was titled 《Reductive arylation of electron-deficient olefins: 4-(4-chlorophenyl)butan-2-one (2-butanone, 4-(4-chlorophenyl)-)》. The information in the text is summarized as follows:

Benzenediazonium compounds 4-RC6H4N2+ (R = H, Br, Cl, OMe, MeCO) were treated with R1CR2:CHR3 (R1 = H, Me, CHMe2, CMe3, Ph; R2 = H, Me; R3 = COMe, CHO, cyano, CO2H, CO2Et) and TiCl3 to yield reductive arylation products I. Thus, CH2:CHCOMe was added to TiCl3 in DMF under N, 4-ClC6H4N2+ Cl- was introduced slowly, and the mixture was stirred to give 4-ClC6H4CH2CH2COMe. In the part of experimental materials, we found many familiar compounds, such as Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Name: Ethyl 3-(4-chlorophenyl)propanoate)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Name: Ethyl 3-(4-chlorophenyl)propanoate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Yamamoto, Yoshikazu; Koizumi, Toru; Katagiri, Kosuke; Furuya, Yui; Danjo, Hiroshi; Imamoto, Tsuneo; Yamaguchi, Kentaro published their research in Organic Letters on December 21 ,2006. The article was titled 《Facile Synthesis of Highly Congested 1,2-Diphosphinobenzenes from Bis(phosphine)boronium Salts》.Application In Synthesis of Ethyl 3-(4-chlorophenyl)propanoate The article contains the following contents:

Bis(phosphine)boronium salts were designed and prepared as key building blocks for the synthesis of highly congested diphosphinobenzenes. The preparation of sterically hindered ortho-phenylene-bridged diphosphines, e.g. 1,2-C6H4[P(Bu-t)2]2 (I), was achieved by the reaction of the bis(phosphine)boronium salts with difluorobenzenechromium complex and subsequent removal of the BH2 group. The steric nature of diphosphine I was revealed in single-crystal x-ray anal. of its Rh complex. After reading the article, we found that the author used Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Application In Synthesis of Ethyl 3-(4-chlorophenyl)propanoate)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. Many organochlorine compounds have been isolated from natural sources ranging from bacteria to humans. Application In Synthesis of Ethyl 3-(4-chlorophenyl)propanoate Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Formula: C11H13ClO2On March 31, 2008, Bohman, B.; Nordlander, G.; Nordenhem, H.; Sunnerheim, K.; Borg-Karlson, A.-K.; Unelius, C. R. published an article in Journal of Chemical Ecology. The article was 《Structure-Activity Relationships of Phenylpropanoids as Antifeedants for the Pine Weevil Hylobius abietis》. The article mentions the following:

Et cinnamate has been isolated from the bark of Pinus contorta in the search for antifeedants for the pine weevil, Hylobius abietis. Based on this lead compound, a number of structurally related compounds were synthesized and tested. The usability of the Topliss scheme, a flow diagram previously used in numerous structure-activity relationship (SAR) studies, was evaluated in an attempt to find the most potent antifeedants. The scheme was initially followed stepwise; subsequently, all compounds found in the scheme were compared. In total, 51 phenylpropanoids were tested and analyzed for SARs by using arguments from the field of medicinal chem. (rational drug design). Individual Hansch parameters based on hydrophobicity, steric, and electronic properties were examined The effects of position and numbers of substituents on the aromatic ring, the effects of conjugation in the mols., and the effects of the properties of the parent alc. part of the esters were also evaluated. It proved difficult to find strong SARs derived from single physicochem. descriptors, but our study led to numerous new, potent, phenylpropanoid antifeedants for the pine weevil. Among the most potent were Me 3-phenylpropanoates monosubstituted with chloro, fluoro, or Me groups and the 3,4-dichlorinated Me 3-phenylpropanoate. After reading the article, we found that the author used Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Formula: C11H13ClO2)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties.Formula: C11H13ClO2 Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Pridmore, Simon J.; Williams, Jonathan M. J. published their research in Tetrahedron Letters on December 22 ,2008. The article was titled 《C-C bond formation from alcohols and malonate half esters using borrowing hydrogen methodology》.Product Details of 7116-36-1 The article contains the following contents:

Alcs. have been used as alkylating agents in a decarboxylative reaction with malonate half esters via a borrowing hydrogen pathway catalyzed by readily available Ru(PPh3)3Cl2. E.g., in presence of Ru(PPh3)3Cl2 and pyrrolidine, reaction of PhCH2OH and EtO2CCH2CO2H gave 88% PhCH2CH2CO2Et. The results came from multiple reactions, including the reaction of Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Product Details of 7116-36-1)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Product Details of 7116-36-1

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Copper-Catalyzed Chemoselective 1,4-Reductions: Sequential One-Pot Synthesis of Esters》 was published in ChemistrySelect in 2019. These research results belong to Kumar, Devarapalli Ravi; Panigrahy, Ram Sankar; Ravi Kishore, Dakoju; Satyanarayana, Gedu. Related Products of 7116-36-1 The article mentions the following:

A sequential one-pot Horner-Wadsworth-Emmons reaction followed by [Cu]-catalyzed 1,4-reduction for an efficient preparation of esters (R1)(R2)CHCH2C(O)OC2H5 (R1 = H, Me; R2 = Ph, naphthalen-1-yl, thiophen-2-yl, 2H-1,3-benzodioxol-5-yl, 4-chlorophenyl, etc.; R1R2 = -(CH2)4-, -(CH2)5-, -(CH2)6-) is described. The protocol showed excellent chemoselectivity and broad functional group tolerance. In addition, the strategy was successfully applied for the synthesis of indanones I (R3 = 4-Me, 5-iso-Pr, 7-methoxy, 5-methoxy; R4 = H, Me) by using a single column chromatog. process. After reading the article, we found that the author used Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Related Products of 7116-36-1)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. Many organochlorine compounds have been isolated from natural sources ranging from bacteria to humans. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Related Products of 7116-36-1

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

In 1989,Journal of Organic Chemistry included an article by Bui The Khai; Arcelli, Antonio. Related Products of 7116-36-1. The article was titled 《A new hydrogen source. 3. Chemoselective reduction with triethylammonium hypophosphite hydrate/Raney nickel and tris(triphenylphosphine)ruthenium dichloride reagents.》. The information in the text is summarized as follows:

Et3NH+ H2PO2-.nH2O (I) acts as a NaH2PO2·H2O modified reagent. Some advantages are noted, including higher product selectivity. Pure aromatic and aliphatic aldehydes are obtained from nitriles by the I/Raney nickel system. The homogeneous catalyst can be used with this reagent. The I/RuCl2(PPh3)3 system selectively reduces aromatic and aliphatic ketones to the corresponding alcs. with excellent yields at room temperature After reading the article, we found that the author used Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Related Products of 7116-36-1)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Related Products of 7116-36-1

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Formula: C11H13ClO2On November 1, 2013 ,《Metal-Catalyzed Benzylic Fluorination as a Synthetic Equivalent to 1,4-Conjugate Addition of Fluoride》 appeared in Journal of Organic Chemistry. The author of the article were Bloom, Steven; Sharber, Seth Andrew; Holl, Maxwell Gargiulo; Knippel, James Levi; Lectka, Thomas. The article conveys some information:

We explore in detail the iron-catalyzed benzylic fluorination of substrates containing aromatic rings and electron-withdrawing groups positioned β to one another, thus providing direct access to β-fluorinated adducts. This operationally convenient process can be thought of not only as a contribution to the timely problem of benzylic fluorination but also as a functional equivalent to a conjugate addition of fluoride, furnishing products in moderate to good yields and in excellent selectivity. The experimental process involved the reaction of Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Formula: C11H13ClO2)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. Many organochlorine compounds have been isolated from natural sources ranging from bacteria to humans. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Formula: C11H13ClO2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Khai, Bui The; Arcelli, Antonio published an article on February 17 ,1989. The article was titled 《A new hydrogen source. 3. Chemoselective reduction with triethylammonium hypophosphite hydrate/Raney nickel and tris(triphenylphosphine)ruthenium dichloride reagents》, and you may find the article in Journal of Organic Chemistry.Reference of Ethyl 3-(4-chlorophenyl)propanoate The information in the text is summarized as follows:

Et3NH+ H2PO2-.nH2O (I) acts as a NaH2PO2·H2O modified reagent. Some advantages are noted, including higher product selectivity. Pure aromatic and aliphatic aldehydes are obtained from nitriles by the I/Raney nickel system. The homogeneous catalyst can be used with this reagent. The I/RuCl2(PPh3)3 system selectively reduces aromatic and aliphatic ketones to the corresponding alcs. with excellent yields at room temperature In the part of experimental materials, we found many familiar compounds, such as Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Reference of Ethyl 3-(4-chlorophenyl)propanoate)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. Reference of Ethyl 3-(4-chlorophenyl)propanoate The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Rates of alkaline hydrolysis of meta-and para-substituted ethyl β-phenylpropionates and correlation with σ0》 was published in Journal of Organic Chemistry in 1966. These research results belong to Fuchs, Richard; Caputo, Joseph A.. Product Details of 7116-36-1 The article mentions the following:

A series of 20 meta-and para-substituted Et β-phenylpropionates were prepared, and the rates of alk. hydrolysis in 87.8% ethanol at 30° measured. The rates generally follow the σ0 values for the substituents estimated from other reactivities and from F19 N.M.R. shielding in similar solvents. The unexpectedly high rate of the m-Me3N+ compound may be due to a direct, short-range electrostatic interaction in the transition state for hydroxide ion attack of the ester. The results came from multiple reactions, including the reaction of Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Product Details of 7116-36-1)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties.Product Details of 7116-36-1 Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics