Category: 7116-36-1

The author of 《The electrostatic influence of substituents on reaction rates. II》 were Westheimer, F. H.. And the article was published in Journal of the American Chemical Society in 1940. HPLC of Formula: 7116-36-1 The author mentioned the following in the article:

cf. C. A. 34, 2236.6. The electrostatic equations derived by Kirkwood and Westheimer (C. A. 32, 8244.8) were applied successfully to calculation of the effect of para substituents on the rate of saponification of Et phenylacetate (I), hydrocinnamate (II), benzoate (III) and cinnamate (IV), to the rate of alk. hydrolysis of benzamides (V) and the rate of reaction of benzyl chlorides (VI) with NaI. Data are given for values of the sp. rate constants, k, for the saponification of p-nitro-I, p-chloro-I, p-methyl-I, p-methoxy-I, p-amino-I, p-chloro-II, p-methoxy-II, p-nitro-VI, p-fluoro-VI, p-chloro-VI, p-bromo-VI, p-iodo-VI, p-nitro-III, p-fluoro-III, p-chloro-III, p-bromo-III, p-iodo-III, p-methyl-III, p-methoxy-III, p-amino-III, p-nitro-IV, p-fluoro-IV, p-chloro-IV, p-bromo-IV, p-iodo-IV, p-methyl-IV; for the alk. hydrolysis of p-nitro-V, p-chloro-V, p-bromo-V, p-iodo-V, p-methyl-V, p-methoxy-V, p-amino-V, and for the reaction between NMe3 and Me p-methylbenzoate and Me p-nitrobenzoate, resp. These are compared with calculated values of k. An approx. equation is derived which applies to dipole-dipole interaction and is shown satisfactorily to account for the effect of substituents on the rate of alkylation of NMe3 by substituted Me benzoates. After reading the article, we found that the author used Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1HPLC of Formula: 7116-36-1)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. Many organochlorine compounds have been isolated from natural sources ranging from bacteria to humans. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. HPLC of Formula: 7116-36-1

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《The unexpected kinetic effect of enzyme mixture: The case of enzymatic esterification》 was written by Zysk, Malgorzata; Zadlo, Anna; Brodzka, Anna; Wisniewska, Catalina; Ostaszewski, Ryszard. Quality Control of Ethyl 3-(4-chlorophenyl)propanoate And the article was included in Journal of Molecular Catalysis B: Enzymatic on April 30 ,2014. The article conveys some information:

During the studies towards synthesis of carboxylic acids esters, using Et carbonate and carboxylic acid as substrates, we found that different single enzyme systems provide model Et 3-phenylpropanoate in very low yield. Systematic studies proved that combination of two or more enzymes enhances yield of reaction. Application of selected enzyme mixture for enzymic esterification of various carboxylic acids provided resp. esters in excellent yields. Unexpectedly, the same reaction performed with mixture of five enzymes proceeds in almost quant. yield. For racemic substrates reaction catalyzed by enzyme mixture was enantioselective. To the best of our knowledge it is the very first evidence of cooperation between multiple enzymes in organic solvents. In addition to this study using Ethyl 3-(4-chlorophenyl)propanoate, there are many other studies that have used Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Quality Control of Ethyl 3-(4-chlorophenyl)propanoate) was used in this study.

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. Many organochlorine compounds have been isolated from natural sources ranging from bacteria to humans. Quality Control of Ethyl 3-(4-chlorophenyl)propanoate Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Computed Properties of C11H13ClO2On March 7, 2022, Calogero, Francesco; Potenti, Simone; Bassan, Elena; Fermi, Andrea; Gualandi, Andrea; Monaldi, Jacopo; Dereli, Busra; Maity, Bholanath; Cavallo, Luigi; Ceroni, Paola; Giorgio Cozzi, Pier published an article in Angewandte Chemie, International Edition. The article was 《Nickel-Mediated Enantioselective Photoredox Allylation of Aldehydes with Visible Light》. The article mentions the following:

Here a practical, highly enantioselective photoredox allylation of aldehydes mediated by chiral nickel complexes with com. available allyl acetate as the allylating agent was reported. The methodol. allowed the clean stereoselective allylation of aldehydes in good to excellent yields and up to 93% e.e. using a catalytic amount of NiCl2(glyme) in the presence of the chiral aminoindanol-derived bis(oxazoline) as the chiral ligand. The photoredox system was constituted by the organic dye 3DPAFIPN and a Hantzsch’s ester as the sacrificial reductant. The reaction proceeded under visible-light irradiation Compared to other published procedures, no metal reductants (such as Zn or Mn), additives (e.g. CuI) or air-sensitive Ni(COD)2 were necessary for this reaction. Accurate DFT calculations and photophys. experiments had clarified the mechanistic picture of this stereoselective allylation reaction. After reading the article, we found that the author used Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Computed Properties of C11H13ClO2)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. Computed Properties of C11H13ClO2 The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Quality Control of Ethyl 3-(4-chlorophenyl)propanoateOn November 4, 1998 ,《Ni(II)-Catalyzed Cross-Coupling between Polyfunctional Arylzinc Derivatives and Primary Alkyl Iodides》 appeared in Journal of the American Chemical Society. The author of the article were Giovannini, Riccardo; Knochel, Paul. The article conveys some information:

A novel nickel-catalyzed coupling reaction of arylzinc bromides ArZnBr (Ar = Ph, 4-ClC6H4, 4-MeOC6H4, 4-NCC6H4, 3-EtO2CC6H4, 2-EtO2CC6H4), generated from the aryl iodides, and functionalized primary alkyl iodides R(CH2)nI (n = 2,3,5; R = Me3CCOO, 2-methyl-1,3-dithiolanyl, EtO2C, BuCO, PhS, (CH2)5NCO) to give aralkyl derivative Ar(CH2)nR in 71-80% yield. Arylzinc bromides are generated from aryl iodides by either treatment of the iodide with Me2CHMgBr in THF followed by addition of ZnBr2 to the Grignard reagent, or by treatment of the aryl iodide with BuLi and addition of ZnBr2. E.g., 4-cyanophenylzinc bromide is formed by transmetalation of 4-NCC6H4I at -90° with BuLi in THF and addition of ZnBr2; the arylzinc bromide was then concentrated and added to a THF solution containing 10 mol% Ni(acac)2, 1 equivalent 4-F3CC6H4CH:CH2, and 1 equivalent Me(SCH2CH2S)CH2CH2I to give I in 80% yield. The absence of 4-F3CC6H4CH:CH2 leads to formation of products formed form homocoupling and zinc-iodine transmetalation of the alkyl iodides. The coupling tolerates ketone, amide, ester, and nitrile functionality and allows coupling of sp2-aryl and sp3-alkyl groups fro which few coupling methods exist. After reading the article, we found that the author used Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Quality Control of Ethyl 3-(4-chlorophenyl)propanoate)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. Quality Control of Ethyl 3-(4-chlorophenyl)propanoate The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

In 1972,Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya included an article by Kadentsev, V. I.; Chizhov, O. S.; Yanovskaya, L. A.; Kucherov, V. F.. Recommanded Product: Ethyl 3-(4-chlorophenyl)propanoate. The article was titled 《Oxygen rearrangement of aromatic and unsaturated acid esters. 4. Mass spectra of p- and m-substituted esters of β-phenylpropionic acid and their heterocyclic analogs》. The information in the text is summarized as follows:

The title mass spectra for meta and para isomers of XC6H4(CH2)2CO2Et (X = Me, MeO, Cl, Br, H), as well as analogs, revealed that the nature of X and its position in the ring both affected the fragmentation. The Class I groups did not interfere with the oxygen-rearrangement, with the meta isomers showing somewhat stronger orienting effect than the para isomers; substituents of Class II inhibited this rearrangement almost totally but did cause a similar rearrangement. Thus, the ester with a m-O2N group was converted to I, while the para isomer yielded II. Both were formed through an intermediate 6-atom ring transition state. In the part of experimental materials, we found many familiar compounds, such as Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Recommanded Product: Ethyl 3-(4-chlorophenyl)propanoate)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Recommanded Product: Ethyl 3-(4-chlorophenyl)propanoate

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The author of 《Selective hydrogenation of α,β-unsaturated carbonyl compounds on silica-supported copper nanoparticles》 were Mendes-Burak, Jorge; Ghaffari, Behnaz; Coperet, Christophe. And the article was published in Chemical Communications (Cambridge, United Kingdom) in 2019. Safety of Ethyl 3-(4-chlorophenyl)propanoate The author mentioned the following in the article:

Silica-supported copper nanoparticles prepared via surface organometallic chem. are highly efficient for the selective hydrogenation of various α,β-unsaturated carbonyl compounds yielding the corresponding saturated esters, ketones, and aldehydes in the absence of additives. High conversions and selectivities (>99%) are obtained for most substrates upon hydrogenation at 100-150 °C and under 25 bar of H2. In the experiment, the researchers used many compounds, for example, Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Safety of Ethyl 3-(4-chlorophenyl)propanoate)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties.Safety of Ethyl 3-(4-chlorophenyl)propanoate Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Butt, G.; Topsom, R. D. published an article in Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy. The title of the article was 《Transmission of substituent effects through extended systems. III. p-Substituted ethyl trans-cinnamates and phenylpropiolates》.Electric Literature of C11H13ClO2 The author mentioned the following in the article:

IR and 13C chem. shifts were determined for Et p-substituted trans-cinnamates and Et phenylpropiolates. The IR data include intensities for the benzene, ethylene, and CO group vibrations which allow an estimation of resonance effects. The relative importance of the various mechanisms of transmission of substituent effects is discussed and compared with those previously reported for p-substituted trans-cinnamonitriles. The CC is less efficient in transmitting substituent effects than the C:C. In the part of experimental materials, we found many familiar compounds, such as Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Electric Literature of C11H13ClO2)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties.Electric Literature of C11H13ClO2 Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Kelkar, S. V.; Joshi, G. S.; Kulkarni, G. H.; Mitra, R. B. published an article on January 31 ,1987. The article was titled 《Synthesis of 3-phenoxybenzyl 3-alkyl-3-(p-substituted phenyl)propionates and 3-phenoxybenzyl 2-alkyl-3-(p-substituted phenyl)propionates》, and you may find the article in Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry.Product Details of 7116-36-1 The information in the text is summarized as follows:

Alkylation of (EtO2C)2CH2 with 4-RC6H4CHR1Br (R = Cl, NO2, H; R1 = Me, Et, H), followed by decarbethoxylation and transesterification with R2OH(R2 = 3-PhOC6H4CH2) gave 4-RC6HCHR1CH2CO2R2 (I). Alkylation of 4-R3C6H4CH2CHR4CO2Et (R3 = H, R4 = Ac; R3 = Cl, R4 = CO2Et) with alkyl halides, followed by deacylation or decarbethoxylation and transesterification with R2OH, gave 4-R3C6H4CH2CHR5CO2R2 (II, R5 = Me2CH, Et, Me). I and II are potential insecticides and acaricides. The experimental process involved the reaction of Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Product Details of 7116-36-1)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. Many organochlorine compounds have been isolated from natural sources ranging from bacteria to humans. Product Details of 7116-36-1 Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The author of 《Intramolecular interactions. Dipole moments and rotational isomerism of a series of 1-substituted 2-arylethanes》 were Camail, Michel; Dicko, Dankoulodo D.. And the article was published in Comptes Rendus des Seances de l’Academie des Sciences, Serie C: Sciences Chimiques in 1971. COA of Formula: C11H13ClO2 The author mentioned the following in the article:

The dipole moments are determined for 12 p-AC6H4CH2CH2X (A = H, Me, Cl; X = Cl, Br, CN, CO2-Et) and used to estimate the anti-gauche isomer equilibrium In the experiment, the researchers used Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1COA of Formula: C11H13ClO2)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. COA of Formula: C11H13ClO2 However, the extent of chlorination is difficult to control. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Pritykin, L. M.; Selyutin, O. B.; Nikolaev, A. L. published their research in Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii) on December 31 ,1999. The article was titled 《Quantitative evaluation of the conjugation effect in the hydrolysis of para-substituted aromatic acid esters》.Product Details of 7116-36-1 The article contains the following contents:

The rate constants of alk. and acid hydrolysis of 10 series of para-substituted benzoic, cinnamic, phenylpropynoic, biphenylcarboxylic, phenylacetic, and 3-phenylpropionic acids linearly correlate with the population of the pz-orbital of the phenylene C atom bearing the substituent. This parameter can be regarded as a quant. measure of the conjugation effect. The experimental process involved the reaction of Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1Product Details of 7116-36-1)

Ethyl 3-(4-chlorophenyl)propanoate(cas: 7116-36-1) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Product Details of 7116-36-1

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics