768-35-4 Archives - Page 2 of 10 - Chlorides-buliding-blocks

Zhang, Jin’s team published research in Organic Letters in 2020 | CAS: 768-35-4

(3-Fluorophenyl)boronic acid(cas: 768-35-4) can be used to make novel liquid crystalline fluorobiphenylcyclohexenes and difluoroterphenyls by palladium-catalyzed cross-couplings also used in the synthesis of o-phenylphenols as potent leukotriene B4 receptor agonists.Category: chlorides-buliding-blocks

Category: chlorides-buliding-blocksIn 2020 ,《Ruthenium(II)-Catalyzed C-H Arylation of N,N-Dialkyl Thiobenzamides with Boronic Acids by Sulfur Coordination in 2-MeTHF》 was published in Organic Letters. The article was written by Zhang, Jin; Liu, Ying; Jia, Qiangqiang; Wang, Yue; Ma, Yangmin; Szostak, Michal. The article contains the following contents:

We report ruthenium(II)-catalyzed ortho-C-H arylation of N,N-dialkylthiobenzamides with boronic acids. The method employs [RuCl2(p-cym)]2 in the presence of Cu(OTf)2 and Ag2O oxidant. The reaction represents the first example of Ru-catalyzed C-H arylation directed by sulfur-containing groups and a rare example of C-H arylation directed by the versatile thiobenzamide moiety. As a further advantage, the method is performed in sustainable and eco-friendly 2-MeTHF as a solvent. In the experiment, the researchers used many compounds, for example, (3-Fluorophenyl)boronic acid(cas: 768-35-4Category: chlorides-buliding-blocks)

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Liu, Cijie’s team published research in Catalysis Letters in 2020 | CAS: 768-35-4

《Palladium Immobilized on 2,2′-Dipyridyl-Based Hypercross linked Polymers as a Heterogeneous Catalyst for Suzuki-Miyaura Reaction and Heck Reaction》 was written by Liu, Cijie; Xu, Wei; Xiang, Dexuan; Luo, Qionglin; Zeng, Shunqin; Zheng, Lijuan; Tan, Yujie; Ouyang, Yuejun; Lin, Hongwei. Recommanded Product: 768-35-4 And the article was included in Catalysis Letters in 2020. The article conveys some information:

2,2′-Bipyridine was successfully integrated into the skeleton of hypercrosslinked polymers networks (HCPs-bipy) via Friedel-Crafts reaction and Scholl coupling reaction, and PdCl2 was locked in this network polymers by coordination with pyridine motif. The preparation of HCPs-bipy has the advantages of low cost, mild conditions, easy separation and high yield. FT-IR, TGA, N2 sorption, ICP, XPS, SEM, EDX and TEM was employed to characterize the structure and composition of the heterogeneous catalysts. The result indicates that HCPs-bipy-Pd possess high sp. surface areas, large microporous volume, thermal stability, and highly dispersion of palladium species. HCPs-bipy-Pd can be applied in Suzuki-Miyaura reactions and Heck reactions as robust heterogeneous catalyst to afford high yield. The reusability test demonstrates that HCPs-bipy-Pd could be recovered and reused for at least five times without losing catalytic activity. In the experiment, the researchers used (3-Fluorophenyl)boronic acid(cas: 768-35-4Recommanded Product: 768-35-4)

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Wang, Shihui’s team published research in Organic Letters in 2021 | CAS: 768-35-4

Wang, Shihui; Xu, Jian; Song, Qiuling published an article in 2021. The article was titled 《Modular Synthesis of Polysubstituted Quinolin-3-amines by Oxidative Cyclization of 2-(2-Isocyanophenyl)acetonitriles with Organoboron Reagents》, and you may find the article in Organic Letters.Name: (3-Fluorophenyl)boronic acid The information in the text is summarized as follows:

A protocol with Mn(III) acetate as a mild one-electron oxidant promoting a radical process to construct polysubstituted quinolin-3-amines was reported. 2-(2-Isocyanophenyl)acetonitriles and organoboron reagents were suitable substrates for this reaction. The remarkable advantages of this protocol were the practical method, mild approach, high reaction efficiency and good compatibility of functional groups, providing straightforward access to functional quinoline derivatives After reading the article, we found that the author used (3-Fluorophenyl)boronic acid(cas: 768-35-4Name: (3-Fluorophenyl)boronic acid)

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Gargaro, Samantha L.’s team published research in Synlett in 2021 | CAS: 768-35-4

Gargaro, Samantha L.; Dunson, Bre’Shon; Sieber, Joshua D. published an article in 2021. The article was titled 《Identification of a Surprising Boronic Acid Homocoupling Process in Suzuki-Miyaura Cross-Coupling Reactions Utilizing a Hindered Fluorinated Arene》, and you may find the article in Synlett.Computed Properties of C6H6BFO2 The information in the text is summarized as follows:

The Suzuki-Miyaura cross-coupling reaction of 2-bromo-1,3-bis(trifluoromethyl)benzene with arylboronic acids was evaluated and determined to suffer from the formation of large amounts of boronic acid homocoupling products in conjunction with dehalogenation. Homocoupling product formation in this process likely occurs through a rare protonolysis/s transmetalation event rather than by the well-established mechanism requiring the involvement of O2. The scope of this boronic acid homocoupling reaction was investigated and shown to predominate with electron-deficient arylboronic acids. Finally, a good yield of cross-coupling products was obtained by employing dicyclohexyl(2′,6′-dimethoxybiphenyl-2-yl)phosphine (SPhos) as the ligand. In the experimental materials used by the author, we found (3-Fluorophenyl)boronic acid(cas: 768-35-4Computed Properties of C6H6BFO2)

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Liu, Jianhui’s team published research in ChemistrySelect in 2019 | CAS: 768-35-4

Computed Properties of C6H6BFO2In 2019 ,《Efficient Access to 3, 4-Diarylpyrroles through Selective Bromination and Subsequent Suzuki-Coupling Reaction》 appeared in ChemistrySelect. The author of the article were Liu, Jianhui; Yu, Yaqiang. The article conveys some information:

An efficient and practical synthesis of 3, 4-disubstituted pyrrole was developed through bromination and the subsequent Suzuki-coupling reaction. The bromination of pyrrole-1-dimethylsulfonamide occurred selectively on the two β-positions to afford 3,4-dibromo-N,N-dimethyl-1H-pyrrole-1-sulfonamide, from which sym. and unsym. 3,4-diarylpyrroles were prepared through a stepwise Suzuki-coupling reaction. This reaction was complementary to the existing methods and was well-tolerable by a variety of functional groups. The bromination was scaled-up to gram-scale synthesis without decreasing the yield. In addition, the other halogenations of pyrrole were also studied and different chloro-products were isolated. The experimental part of the paper was very detailed, including the reaction process of (3-Fluorophenyl)boronic acid(cas: 768-35-4Computed Properties of C6H6BFO2)

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Wu, Chun-Yan’s team published research in Organic Letters in 2019 | CAS: 768-35-4

Quality Control of (3-Fluorophenyl)boronic acidIn 2019 ,《Construction of Chiral 1,3-Diamines through Rhodium-Catalyzed Asymmetric Arylation of Cyclic N-Sulfonyl Imines》 was published in Organic Letters. The article was written by Wu, Chun-Yan; Xu, Ming-Hua. The article contains the following contents:

A rhodium/sulfur-olefin complex catalyzed asym. 1,2-addition of arylboronic acids to six-membered 1,2,6-thiadiazinane 1,1-dioxide-type cyclic imines to access highly optically active sulfamides (95-99% ee) has been developed. By taking advantage of the simple functional group transformations, an interesting array of valuable chiral 1,3-diamines with different substitution patterns can be readily obtained in a highly enantioenriched manner. In the experiment, the researchers used many compounds, for example, (3-Fluorophenyl)boronic acid(cas: 768-35-4Quality Control of (3-Fluorophenyl)boronic acid)

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Cui, Guo-Qing’s team published research in Organic Letters in 2021 | CAS: 768-35-4

Cui, Guo-Qing; Dai, Jing-Cheng; Li, Yan; Li, Yuan-Bo; Hu, Duo-Duo; Bian, Kang-Jie; Sheng, Jie; Wang, Xi-Sheng published their research in Organic Letters in 2021. The article was titled 《Copper-Catalyzed Enantioselective Arylation via Radical-Mediated C-C Bond Cleavage: Synthesis of Chiral ω,ω-Diaryl Alkyl Nitriles》.Computed Properties of C6H6BFO2 The article contains the following contents:

The first example of copper-catalyzed ring-opening, enantioselective arylation of cyclic ketoxime esters to access ω,ω-diaryl alkyl nitriles has been developed in high yield (up to 92% yield) with excellent enantioselectivity (up to 91% ee). Side-arm bis(oxazoline) ligand plays a significant role in this asym. catalytic transformation, which provides an efficient route to construct diverse chiral ω,ω-diaryl alkyl nitriles. Synthetic utility has also been demonstrated in the further derivatization of the ω,ω-diaryl alkyl nitrile to corresponding amide. In the experiment, the researchers used (3-Fluorophenyl)boronic acid(cas: 768-35-4Computed Properties of C6H6BFO2)

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Liu, Bingxian’s team published research in Organic Letters in 2021 | CAS: 768-35-4

Liu, Bingxian; Yang, Lingyun; Dong, Zhenzhen; Chang, Junbiao; Li, Xingwei published an article in 2021. The article was titled 《Rh(III)-Catalyzed Annulation of 2-Biphenylboronic Acid with Diverse Activated Alkenes》, and you may find the article in Organic Letters.Synthetic Route of C6H6BFO2 The information in the text is summarized as follows:

Rhodium(III)-catalyzed annulation of 2-biphenylboronic acids I (R = R1 = H; R = 4-Me, R1 = 4-Me; R = 6-MeO, R1 = 2′-MeO; R = 5-F, R1 = 3′-F; etc.) with three classes of activated alkenes, e.g., (E)-R2C(O)CH=CHCF3 (R2 = 4-MeC6H4, naphthalen-1-yl, furan-2-yl, etc.), II (R3 = n-Pr, Ph, 2-BrC6H4, etc.), and cyclohex-2-en-1-one, has been realized, leading to the synthesis of fused or bridged cyclic skeletons, e.g., III (R4 = R5 = H; R4 = 2-Me, R5 = 7-Me; R4 = 4-MeO, R5 = 5-MeO ) and IV (R6 = R7 = H; R6 = 1-F, R7 = 11-F; R6 = 3-tert-Bu, R7 = 9-tert-Bu; etc.), via transmetalation-initiated C-H activation. In the annulative coupling of 2-biphenylboronic acid with a CF3-substituted enone, the bulky cyclopentadienyl ligand (CptBu) in the catalyst proved effective in promoting the reductive elimination process prior to protonolysis, affording the [4+2]-annulated products III instead of the simple 1,4-addition product. Seven-membered rings IV were obtained when disubstituted cyclopropenones II were employed. Bridged cycles V (R8 = H, Me) and 2-(tert-butyl)triphenylene-1,4-dione were isolated from the coupling of 2-biphenylboronic acid with benzoquinone, 2-methylbenzoquinone, and 2-(tert-butyl)benzoquinone as a result of 2-fold Michael additions The substrate scopes were found to be broad with up to 99% yield under air-tolerant conditions. In the experiment, the researchers used (3-Fluorophenyl)boronic acid(cas: 768-35-4Synthetic Route of C6H6BFO2)

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Baek, Doohyun’s team published research in Chemical Science in 2020 | CAS: 768-35-4

《Catalytic enantioselective synthesis of tetrasubstituted chromanones via palladium-catalyzed asymmetric conjugate arylation using chiral pyridine-dihydroisoquinoline ligands》 was written by Baek, Doohyun; Ryu, Huijeong; Ryu, Ji Yeon; Lee, Junseong; Stoltz, Brian M.; Hong, Sukwon. Quality Control of (3-Fluorophenyl)boronic acid And the article was included in Chemical Science in 2020. The article conveys some information:

Highly enantioselective conjugate addition reactions of arylboronic acids to 2-substituted chromones catalyzed by palladium complexes with new chiral pyridine-dihydroisoquinoline (PyDHIQ) ligands was developed. These reactions provide highly enantioselective access to chromanones containing tetrasubstituted stereocenters. Various arylboronic acids and 2-substituted chromones were used in the catalytic reaction which afforded the chiral tetrasubstituted chromanones in good yields and excellent enantioselectivities (25 examples, up to 98% yields, up to 99% ee). The results came from multiple reactions, including the reaction of (3-Fluorophenyl)boronic acid(cas: 768-35-4Quality Control of (3-Fluorophenyl)boronic acid)

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Saranya, Salim’s team published research in ChemistrySelect in 2021 | CAS: 768-35-4

Saranya, Salim; Radhika, Sankaran; Anilkumar, Gopinathan published their research in ChemistrySelect in 2021. The article was titled 《Ligand- and Base-Free Cu-Catalyzed C-N Coupling of Aminoquinolines with Boronic Acids》.Application In Synthesis of (3-Fluorophenyl)boronic acid The article contains the following contents:

A ligand- and base-free Cu-catalyzed protocol for the synthesis of N-arylquinolin-8-amine and N-arylquinolin-3-amine derivatives has been developed. A wide range of N-aryl heterocycles were synthesized in moderate to good yields under the mild condition of 10 mol% Cu(OAc)2 in 3 mL methanol at room temperature in presence of air. The results came from multiple reactions, including the reaction of (3-Fluorophenyl)boronic acid(cas: 768-35-4Application In Synthesis of (3-Fluorophenyl)boronic acid)

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics