Category: 866-23-9

Villieras, Jean published the artcileα-Haloenolates; VII. Diethyl 1-chloro-1-ethoxycarbonyl-1-lithiomethanephosphonate; a convenient one-step preparation of α-chloro-α,β-unsaturated esters from diethyl trichloromethanephosphonate, Quality Control of 866-23-9, the publication is Synthesis (1978), 31-3, database is CAplus.

α,β-Unsaturated esters (E)- and (Z)-RCH:CClCO₂Et (R = n-C₉H₁₉, BuCHEt, 3-cyclohexenyl, Cl₃C, Ph, 2-ClC₆H₄, 4-MeOC₆H₄) and I (n = 0, 1) were prepared by treating Cl₃CP(O)(OEt)₂ with BuLi at -90°, ClCO₂Et at -125°, and RCHO or the cycloalkanone at -60 to +20°. Hydrolysis of the intermediate Li enolate formed in the above reactions gave EtO₂CCHClP(O)(OEt)₂.

Synthesis published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C6H4ClNO2, Quality Control of 866-23-9.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Villieras, Jean published the artcileα-Chloroenolates; VI. Diethyl 1-chloro-1-lithio-2-oxoalkanephosphonates; synthesis of α-chloro-α,β-unsaturated ketones, Category: chlorides-buliding-blocks, the publication is Synthesis (1978), 29-31, database is CAplus.

1-Chloro-2-oxoalkanephosphonates RCOCHClP(O)(OEt)₂ (I; R = Pr, iso-Pr, tert-Bu) were prepared in 60-85% yield by treating LiCCl₂P(O)(OEt)₂ with BuLi at -90° followed by acylation with RCOCl at -125 and hydrolysis. In situ reaction of I α-Li derivatives with aldehydes R¹CHO (R¹ = Ph, 2- or 4-ClC₆H₄, Bu) gave α,β-unsaturated ketones (E)-R¹CH:CClCOR.

Synthesis published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C7H8BNO4, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Corallo, Marcel published the artcileStudy of the reaction of α-chlorinated alkylphosphonyl dichlorides with alcohols and amines, Product Details of C5H10Cl3O3P, the publication is Phosphorus and Sulfur and the Related Elements (1978), 4(1), 19-25, database is CAplus.

Condensation reactions of alcs. and amines with Cl₃CP(O)Cl₂ and with α,α-dichlorinated alkylphosphonyl dichlorides were investigated. The best results were obtained in solution with Et₃N as HCl trapping agent. Thus, reaction of Cl₃CP(O)Cl₂ with MeOH at -20° gave Cl₃P(O)(OMe)Cl. Several side reactions occur, one leading to triethylammonium phosphonates. The exptl. conditions for the stepwise esterification of α-chlorinated phosphonyl dichlorides were also given.

Phosphorus and Sulfur and the Related Elements published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, Product Details of C5H10Cl3O3P.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Biswas, Sourish published the artcileNickel-catalyzed insertions of vinylidenes into Si-H bonds, Quality Control of 866-23-9, the publication is Chemical Communications (Cambridge, United Kingdom) (2020), 56(91), 14175-14178, database is CAplus and MEDLINE.

A nickel-catalyzed reductive cyclization of 1,1-dichloroalkenyl silanes is reported. The products of this reaction are unsaturated five- or six-membered silacycles. Intermol. variants are also described, providing access to trisubstituted vinyl silanes that are not accessible by alkyne hydrosilylation or sila-Heck-type processes. A variety of silanes can be utilized, including those that serve as nucleophilic partners in Hiyama cross-coupling reactions. Mechanistic studies using deuterium-labeled silanes are described.

Chemical Communications (Cambridge, United Kingdom) published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, Quality Control of 866-23-9.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Gramstad, Thor published the artcileHydrogen bonding. XXVI. Proton NMR studies of hydrogen bonding between thiophenol and phosphoryl compounds. Hiquchi plot. Solvent effect, SDS of cas: 866-23-9, the publication is Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy (1974), 30A(11), 2121-31, database is CAplus.

The association constants, (Ka), entropy, and enthalpy (ΔH) for the H-bonding of PhSH with 6 phosphoryl compounds, e.g., (EtO)2P(O)CCl3, were determined using the Hiquchi plot. ΔH and log Ka were both linearly dependent on the change in NMR chem. shift, Δδx, and with ir frequency shift δυSH, and δΔx and σν were linearly related. On going from CCl4 to cyclohexane solvent Ka and -δH were greatly increased whereas δx and δΔx were considerably decreased. A relation between the energy changes between S-H and C-H and S-H and O-H proton donors was established.

Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, SDS of cas: 866-23-9.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Tanino, Keiji published the artcileTotal Synthesis of Ingenol, Quality Control of 866-23-9, the publication is Journal of the American Chemical Society (2003), 125(6), 1498-1500, database is CAplus and MEDLINE.

Total synthesis of ingenol (I), a diterpene isolated from the genus Euphorbia, was accomplished on the basis of the novel key reactions. The highly strained ingenane skeleton was constructed through an intramol. cyclization reaction of an acetylene dicobalt complex followed by a rearrangement reaction of an epoxy alc. II. The C(3),C(4),C(5)-triol moiety was introduced by a stereoselective double dihydroxylation reaction of a diene having C(2)-C(3) and C(4)-C(5) double bonds.

Journal of the American Chemical Society published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C7H7ClN2S, Quality Control of 866-23-9.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Berte-Verrando, Sylvie published the artcileGeneral synthesis of α,α-dideuteriated phosphonic esters, Product Details of C5H10Cl3O3P, the publication is Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) (1994), 821-4, database is CAplus.

A range of α,α-dideuteriated phosphonic esters has been prepared by deuteriolysis of α-silylated α-phosphonylated carbanions with D₂O as deuterium source. In most cases, incorporation of deuterium is greater than 95% and the yields are good to excellent. The title products are potential trace compounds in many biol. and industrial applications.

Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999) published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, Product Details of C5H10Cl3O3P.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Iyoda, Masahiko published the artcileSynthesis and properties of a bisdehydro[14]annuleno[c]furan and an ortho-annelated tetrakisdehydro[14]annuleno[14]annulene, Recommanded Product: Diethyltrichloromethylphosphonate, the publication is Bulletin of the Chemical Society of Japan (1994), 67(3), 778-91, database is CAplus.

A bisdehydro[14]annuleno[c]furan I and a tetrakisdehydro[14]annuleno[14]annulene II have been synthesized; their properties and effects of annulation on annulene rings are discussed on the basis of ¹H NMR and electronic spectra. Attempts to synthesize the related [14]annuleno[16]annuleno[14]annulene are also described.

Bulletin of the Chemical Society of Japan published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, Recommanded Product: Diethyltrichloromethylphosphonate.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Bakkas, S. published the artcileDifference in behavior of the reactive electrophiles diethyl trichloromethylphosphonate and carbon tetrachloride towards triethyl phosphite, Related Products of chlorides-buliding-blocks, the publication is Phosphorus, Sulfur and Silicon and the Related Elements (2000), 211-224, database is CAplus.

The reaction of tri-Et phosphite with di-Et trichloromethylphosphonate 2b in the absence of solvents and catalysts yields mainly di-Et (1,1-dichloropropyl)phosphonate and di-Et dichloromethylphosphonate. These main products are accompanied by a variety of byproducts which differ considerably from those obtained in the reaction between tri-Et phosphite and CCl₄. Both reactions would begin by a halophilic substitution of tri-Et phosphite on the pos. halogen. For di-Et trichloromethylphosphonate the formed carbanion would then attack preferentially the C β to P⁺ and the H γ to P⁺ on heterophosphonium cation. In contrast, the less sterically hindered trichloromethyl carbanion formed by the halophilic attack of tri-Et phosphite on CCl₄ would rather attack mainly the pos. P⁺ of this cation. The tetra-Et (dichloromethylene)bisphosphonate previously reported by V. P. Kukhar and E. I. Sagina (1979) to be the main product formed in the thermal reaction between tri-Et phosphite and di-Et trichloromethylphosphonate was not found under the authors’ conditions. Its formation only under photochem. irradiation were observed

Phosphorus, Sulfur and Silicon and the Related Elements published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Perlikowska, Wieslawa published the artcileOne-pot stereoselective synthesis of (Z)-diethyl α-chlorovinylphosphonates, Application of Diethyltrichloromethylphosphonate, the publication is Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1997), 967-970, database is CAplus.

Di-Et trichloromethylphosphonate, treated with BuLi followed by an aldehyde (or cycloalkenone), was converted to α-chlorovinylphosphonates, e.g. 85% (Z)-PhCH:C(Cl)(PO₃Et₂), via the intermediate formation of a bisphosphonate and a Wadsworth-Emmons olefination. High (Z) stereoselectivity of the reaction is discussed in terms of the conformational preferences of the adducts.

Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, Application of Diethyltrichloromethylphosphonate.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics