Category: 95-49-8

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 95-49-8, name is 1-Chloro-2-methylbenzene, A new synthetic method of this compound is introduced below., name: 1-Chloro-2-methylbenzene

In a 250 mL four-necked flask was added 141 mL (150 g) o-chlorotoluene, adding 3.0 g Hbeta molecular sieve catalyst, stirring to disperse evenly; and then into the system by 50 mL / min sulfuric acid dry chlorine gas, at 35 C for 12 h to give dichlorotoluene. After the exhaust gas is condensed, the unreacted Cl2 is removed by the NaOH solution.

The synthetic route of 95-49-8 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Nanjing Zhongteng Chemical Co., Ltd.; Zhong Hua; Lu Minshan; Chen Xiuzhen; Liu Qiaobao; Yin Hengbo; Wang Aili; (8 pag.)CN104876790; (2017); B;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Electric Literature of 95-49-8, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 95-49-8 as follows.

A 100 mL four-necked flask was charged with 47 mL (50 g) o-chlorotoluene, 0.25 g [BMIM]Cl-2AlCl3 was added, The ionic liquid is stirred to disperse evenly. And then into the system 20 mL / min by concentrated sulfuric acid drying of chlorine, Reaction at 30 C for 12 h to give dichlorotoluene, The tail gas is removed by NaOH solution to remove unreacted Cl2.

According to the analysis of related databases, 95-49-8, the application of this compound in the production field has become more and more popular.

Reference:
Patent; NANJING ZHONGTENG CHEMICAL CO LTD; JIANGSU ZHONGTENG CHEMICAL CO LTD; Zhong, Hua; Lu, Minshan; Chen, Xiuzhen; Liu, Qiaobao; (7 pag.)CN104803827; (2016); B;,
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics