Category: 95-88-5

A FRET chemosensor for hypochlorite with large Stokes shifts and long-lifetime emissions was written by Liu, Zhiwei;Song, Fengling;Song, Bo;Jiao, Long;An, Jing;Yuan, Jingli;Peng, Xiaojun. And the article was included in Sensors and Actuators, B: Chemical in 2018.Recommanded Product: 95-88-5 The following contents are mentioned in the article:

A FRET-based chemosensor for hypochlorite was developed, both the donor and acceptor of this FRET system are fluorophores with a large Stokes shift. The donor has two comparable excitation peaks at 460 nm and 575 nm. And it is found FRET-sensitized emission has less interference from direct-excited acceptor emission when excitation at 460 nm compared with excitation at 575 nm. The sensitivity can be improved for 4-fold (<95 nM). Meanwhile the donor can be excited by two-photon excitation source, which is an anti-Stokes shift property. It makes the chemosensor totally to get rid of the direct-excited acceptor emission for the FRET sensing method. Furthermore, the long lifetime luminescence of the FRET pairs makes them possible to be used in time-resolved technol., this can overcome the autofluorescence interference from biol. matrix. All above characters implied this FRET pairs have more potential to be applied in hypochlorite detection of biol. samples. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Recommanded Product: 95-88-5).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Recommanded Product: 95-88-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

A Rationally Designed, General Strategy for Membrane Orientation of Photoinduced Electron Transfer-Based Voltage-Sensitive Dyes was written by Kulkarni, Rishikesh U.;Yin, Hang;Pourmandi, Narges;James, Feroz;Adil, Maroof M.;Schaffer, David V.;Wang, Yi;Miller, Evan W.. And the article was included in ACS Chemical Biology in 2017.SDS of cas: 95-88-5 The following contents are mentioned in the article:

Voltage imaging with fluorescent dyes offers promise for interrogating the complex roles of membrane potential in coordinating the activity of neurons in the brain. Yet, low sensitivity often limits the broad applicability of optical voltage indica-tors. In this paper, the authors use mol. dynamics (MD) simulations to guide the design of new, ultra-sensitive fluorescent voltage indicators that use photoinduced electron transfer (PeT) as a voltage-sensing switch. MD simulations predict an approx. 16% increase in voltage sensitivity resulting purely from improved alignment of dye with the membrane. The authors confirm this theor. finding by synthesizing 10 new voltage-sensitive (VoltageFluor, or VF) dyes and establishing that all of them display the expected improvement of approx. 19%. This synergistic outworking of theory and experiment enabled computational and theor. estimation of VF dye orientation in lipid bilayers and has yielded the most sensitive PeT-based VF dye to date. The authors use this new voltage indicator to monitor voltage spikes in neurons from rat hippocampus and human pluripotent stem cell-derived dopaminergic neurons. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5SDS of cas: 95-88-5).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.SDS of cas: 95-88-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Microwave-assisted synthesis and antifungal activity of coumarin[8,7-e][1,3]oxazine derivatives was written by Zhang, Ming-Zhi;Zhang, Rong-Rong;Yin, Wen-Zheng;Yu, Xiang;Zhang, Ya-Ling;Liu, Pin;Gu, Yu-Cheng;Zhang, Wei-Hua. And the article was included in Molecular Diversity in 2016.Name: 4-Chlororesorcinol The following contents are mentioned in the article:

The synthesis of novel coumarin[8,7-e][1,3]oxazine derivatives I (R = C₆H₅, 4-H₃CC₆H₄, 4-ClC₆H₄, CH₂C₆H₅; R¹ = H, Cl; R² = CH₃, C₆H₅, CF₃; R³ = H, Me) through a microwave-assisted three-component one-pot Mannich reaction have been described in this study. All the target compounds I were evaluated in vitro for their antifungal activity against Botrytis cinerea, Colletotrichum capsici, Alternaria solani, Gibberella zeae, Rhizoctonia solani, and Alternaria mali. The preliminary bioassays showed that I (R = C₆H₅, 4-ClC₆H₄; R¹ = Cl; R² = CH₃, CF₃; R³ = H, CH₃) exhibited good antifungal activity and the most active compound I (R = C₆H₅; R¹ = Cl; R² = CF₃; R³ = H) shows an EC₅₀ value as low as 2.1 nM against Botrytis cinerea. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Name: 4-Chlororesorcinol).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Name: 4-Chlororesorcinol

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Wastewater treatment: Degradation of 2,4-dichlorophenoxyacetic acid by anodic oxidation and electro-Fenton using BDD anode was written by Cai, Jingju;Zhou, Minghua;Pan, Yuwei;Lu, Xiaoye. And the article was included in Separation and Purification Technology in 2020.Recommanded Product: 95-88-5 The following contents are mentioned in the article:

The degradation of 2,4-dichlorophenoxyacetic acid (2,4-D) was conducted by anodic oxidation (AO) with a boron-doped diamond (BDD) anode, and was greatly enhanced by combination with electro-Fenton (EF) using carbon black modified graphite felt (CB-GF) as cathode. A high c.d., low initial pH and high concentration of Na₂SO₄ favored for the 2,4-D degradation by AO. In EF, 2,4-D degradation rate increased 8 times after using CB-GF cathode, obtaining a higher mineralization current efficiency (53%) and a lower energy consumption (71.8 kWh kg^-1 TOC) due to the higher generation of H₂O₂. It indicated that the mainly contributing radicals for 2,4-D degradation by AO was ^·OH (57.5%), while the contribution improved to 92% by EF. Compared with AO, EF was more efficient and complete for 2,4-D degradation, confirmed by the detection of the main degradation intermediates and short-chain carboxylic acids. This work demonstrated that EF using BDD anode and high-performance CB-GF cathode was efficient for 2,4-D degradation, which would be a promising electrochem. advanced oxidation process for organic wastewater treatment. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Recommanded Product: 95-88-5).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Recommanded Product: 95-88-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Photosensitive bent-core nematic liquid crystals with various linking units in the side arms: Structure-properties relationships was written by Smahel, Michal;Poryvai, Anna;Xiang, Ying;Pociecha, Damian;Troha, Tinkara;Novotna, Vladimira;Svoboda, Jiri;Kohout, Michal. And the article was included in Journal of Molecular Liquids in 2020.Reference of 95-88-5 The following contents are mentioned in the article:

We present two isomeric series of photosensitive bent-core liquid crystals possessing a lateral chlorine atom in the central resorcinol unit and various linking units in the side arms. With the aim to tune properties of the nematic phase, we have varied the type of the linking unit in the lengthening arm with rising rigidity from benzoate ester, biphenyl, cinnamate, Schiff base to stilbene moieties. In addition to that, we have changed the position of the lateral substituent (chlorine) as well. The mesomorphic properties of the materials have been determined from differential scanning calorimetry, polarizing optical microscopy, dielec. spectroscopy and X-ray studies. We show that synergy of the linking unit with the effect of the lateral substituent gives rise to broad temperature range of mesophases – the nematic phase as well as a SmCP phase. Thanks to the presence of the photosensitive group in the mol. structure, we have been able to transform both mesophases to the isotropic phase under UV light. The chem. structure-mesomorphic properties relationships are discussed with the aid of ab initio calculations and the results presented in context with exptl. data. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Reference of 95-88-5).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Organochlorine compounds are lipophylic, meaning they are more soluble in fat than in water. This gives them a high tenancy to accumulate in the food chain (biomagnification).Reference of 95-88-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

A urea-modified tryptophan based in situ reducing and stabilizing agent for the fabrication of gold nanoparticles as a Suzuki-Miyaura cross-coupling catalyst in water was written by Sasmal, Supriya;Debnath, Mintu;Nandi, Sujay Kumar;Haldar, Debasish. And the article was included in Nanoscale Advances in 2019.Electric Literature of C6H5ClO2 The following contents are mentioned in the article:

Urea-modified tryptophan has been used as an in situ reducing and stabilizing agent for the fabrication of gold nanoparticles in water. The tryptophan side chain NH has been used for the reduction of gold ions in HAuCl₄ to metallic gold and carboxylic acid functionality helps to stabilize the gold nanoparticles. This was confirmed by a controlled reaction with urea-modified leucine which failed to form any gold nanoparticles. The resultant gold nanoparticles have been characterized by various spectroscopic techniques such as UV-visible spectroscopy, FT-IR spectroscopy and microscopic techniques such as FE-SEM and TEM. Moreover, we have shown that the urea-modified tryptophan stabilized gold nanoparticles catalyze the Suzuki-Miyaura cross-coupling reaction. The gold nanoparticle catalyzed Suzuki-Miyaura cross-coupling reaction between 4-bromobenzoic acid and phenylboronic acid in water provides 92% yield in 40 min. The high efficiency exhibited by the gold nanoparticle catalyst was effectively translated to a large number of Suzuki-Miyaura reactions between halides with phenylboronic acid. The results may inspire further research on gold nanoparticles catalysis in water. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Electric Literature of C6H5ClO2).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Organic chlorides are compounds containing a carbon-chlorine bond, which are widely used in the oil field as a wax dissolver. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Electric Literature of C6H5ClO2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

A Dual Functional Electroactive and Fluorescent Probe for Coupled Measurements of Vesicular Exocytosis with High Spatial and Temporal Resolution was written by Liu, Xiaoqing;Savy, Alexandra;Maurin, Sylvie;Grimaud, Laurence;Darchen, Francois;Quinton, Damien;Labbe, Eric;Buriez, Olivier;Delacotte, Jerome;Lemaitre, Frederic;Guille-Collignon, Manon. And the article was included in Angewandte Chemie, International Edition in 2017.Safety of 4-Chlororesorcinol The following contents are mentioned in the article:

In this work, Fluorescent False Neurotransmitter 102 (FFN102), a synthesized analog of biogenic neurotransmitters, was demonstrated to show both pH-dependent fluorescence and electroactivity. To study secretory behaviors at the single-vesicle level, FFN102 was employed as a new fluorescent/electroactive dual probe in a coupled technique (amperometry and total internal reflection fluorescence microscopy (TIRFM)). We used N13 cells, a stable clone of BON cells, to specifically accumulate FFN102 into their secretory vesicles, and then optical and electrochem. measurements of vesicular exocytosis were exptl. achieved by using indium tin oxide (ITO) transparent electrodes. Upon stimulation, FFN102 started to diffuse out from the acidic intravesicular microenvironment to the neutral extracellular space, leading to fluorescent emissions and to the electrochem. oxidation signals that were simultaneously collected from the ITO electrode surface. The correlation of fluorescence and amperometric signals resulting from the FFN102 probe allows real-time monitoring of single exocytotic events with both high spatial and temporal resolution This work opens new possibilities in the investigation of exocytotic mechanisms. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Safety of 4-Chlororesorcinol).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Safety of 4-Chlororesorcinol

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Facilely prepared Cl-doped graphene as an efficient anode for the electrochemical catalytic degradation of acetaminophen was written by Zhang, Qian;Wang, Bingxin;Hong, Jun-Ming. And the article was included in Journal of Nanoscience and Nanotechnology in 2021.Application of 95-88-5 The following contents are mentioned in the article:

The application of electrochem. catalytic oxidation in wastewater treatment with powerful Cl doped graphene as an anode has been discussed as a novel approach to degrade acetaminophen effectively. The application of electrochem. catalytic oxidation in wastewater treatment with powerful Cl doped graphene as an anode has been discussed as a novel approach to degrade acetaminophen effectively. The characteristics of Cl-doped graphene that were related to Cl loading content and microscopic morphol. were analyzed by using several instruments, and the defects created by Cl doping were identified. Quenching experiments and ESR detection were proposed to clarify the mechanism underlying the production of active free radicals by Cl doped graphene. The degradation results indicated that efficiency increased with the percentage of Cl atoms doped into the graphene. The best degradation efficiency of acetaminophen could reach 98% when Cl-GN-12 was used. In the process of electrocatalytic oxidation, Oâ€?sup>-₂, and active chlorine, as the main active species, persistently attacked acetaminophen into open-ring intermediates, such as 4-chlororesorcinol, and finally into CO₂ and H₂O. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Application of 95-88-5).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Application of 95-88-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Noninvasive ratiometric fluorescence imaging of γ-glutamyltransferase activity using an activatable probe was written by Huang, Zheng;An, Ruibing;Wei, Shixuan;Wang, Jinfang;Ye, Deju. And the article was included in Analyst (Cambridge, United Kingdom) in 2021.Formula: C6H5ClO2 The following contents are mentioned in the article:

γ-Glutamyltranspeptidase (GGT) is an important aminopeptidase overexpressed in many malignant tumors, and accurate detection of its activity is useful for the diagnosis and treatment of tumors. Herein, we report a GGT-activatable ratiometric fluorescent probe (1) constructed by covalently linking an ‘always-on’ BODIPY fluorophore with a GGT-activatable near-IR (NIR) fluorescent substrate. Upon interaction with GGT, the NIR fluorescence at 735 nm in probe 1 is significantly enhanced, while the fluorescence of BODIPY at 517 nm remains unchanged. Using BODIPY fluorescence as an internal standard, significantly enhanced ratiometric fluorescence between 735 nm and 517 nm could be achieved, allowing accurate detection of the activity of GGT in living subjects independent of probe concentration We demonstrate that probe 1 is feasible for the evaluation of GGT levels in different tumor cells and differentiation of GGT-pos. tumor cells from GGT-neg. normal tissue cells. Moreover, probe 1 is further applied for the visualization of tumor via noninvasive ratiometric fluorescence imaging of GGT activity, which could facilitate the detection of GGT-pos. tumor tissues and study of GGT-related pathol. processes. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Formula: C6H5ClO2).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Formula: C6H5ClO2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Activatable Near-Infrared Probe for Fluorescence Imaging of γ-Glutamyl Transpeptidase in Tumor Cells and In Vivo was written by Luo, Zhiliang;Feng, Liandong;An, Ruibing;Duan, Guanfu;Yan, Runqi;Shi, Hua;He, Jian;Zhou, Zhengyang;Ji, Changge;Chen, Hong-Yuan;Ye, Deju. And the article was included in Chemistry – A European Journal in 2017.Safety of 4-Chlororesorcinol The following contents are mentioned in the article:

γ-Glutamyl transpeptidase (GGT) is a cell-membrane-bound enzyme that is involved in various physiol. and pathol. processes and is regarded as a potential biomarker for many malignant tumors, precise detection of which is useful for early cancer diagnosis. Herein, a new GGT-activatable near-IR (NIR) fluorescence imaging probe (GANP) by linking of a GGT-recognitive substrate γ-glutamate (γ-Glu) and a NIR merocyanine fluorophore (mCy-Cl) with a self-immolative linker p-aminobenzyl alc. (PABA) is reported. GANP was stable under physiol. conditions, but could be efficiently activated by GGT to generate â‰?00-fold enhanced fluorescence, enabling high sensitivity (detection limit of â‰?.6 mU L^-1) and specificity for the real-time imaging of GGT activity as well as rapid evaluation of the inhibition efficacy of GGT inhibitors in living tumor cells. Notably, the deep tissue penetration ability of NIR fluorescence could further allow GANP to image GGT in frozen tumor tissue slices with large penetration depth (>100 μm) and in xenograft tumors in living mice. This GGT activatable NIR fluorescence imaging probe could facilitate the study and diagnosis of other GGT-correlated diseases in vivo. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Safety of 4-Chlororesorcinol).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids.While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available. Alkyl chlorides readily undergo attack by nucleophiles.Safety of 4-Chlororesorcinol

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics