Category: 95-88-5

Removal of pesticide 2,4-D by conductive-diamond photoelectrochemical oxidation was written by Souza, F. L.;Saez, C.;Lanza, M. R. V.;Canizares, P.;Rodrigo, M. A.. And the article was included in Applied Catalysis, B: Environmental in 2016.Reference of 95-88-5 The following contents are mentioned in the article:

The removal of pesticide 2,4-D by single photolysis, electrolysis with BDD anode and a combined UV irradiation-electrolysis was studied. Although photolysis is completely inefficient in the degradation of this pesticide, light irradiation improves significantly the results obtained by single electrolysis, leading to harsher oxidation conditions, which contribute to reduce the number of intermediates and promote mineralization. Electrolysis with diamond electrodes can attain the complete depletion of the pesticide and its mineralization regardless the c.d. applied and the light irradiation In comparing the effect of c.d., the process is much efficient operating at 10 mA cm^-2, attaining complete mineralization with specific current charges <10 Ah dm^-3, in spite of being detected a lower concentration of oxidants. Under absence of chlorides in the supporting electrolyte main intermediates formed were hydroquinone and 4-chlororesorcinol. Under the presence of this anion, 2-chlorophenol and 4-chlorophenol were also observed at high concentrations UV irradiation does not modify the intermediates formed although concentration is lower. An oxidation mechanism is proposed in agreement with other works shown in the literature. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Reference of 95-88-5).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Organic chlorides can be used in production of: PVC, pesticides, chloromethane, teflon, insulators. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.Reference of 95-88-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Sensitive and Selective Detection of Enterococcus faecalis Using a New Turn-on Fluorogenic β-glucosidase Substrate Combined with a Modified Selective Broth was written by Wei, Xianhu;Gu, Qihui;Feng, Ying;Zhang, Youxiong;Li, Ying;Zhang, Shuhong;Zhang, Jumei;Wu, Shi;Yang, Xiaojuan;Ye, Qinghua;Ding, Yu;Wang, Juan;Chen, Moutong;Wu, Qingping. And the article was included in Photochemistry and Photobiology.Computed Properties of C6H5ClO2 The following contents are mentioned in the article:

A new, simple-to-synthesize and sensitive turn-on fluorogenic substrate (CFMU-Glu) for β-glucosidase activity was developed. This probe was based on a 7-hydroxycoumarin derivative (CFMU) that could emit green fluorescence and had the low pK_a value of 5.61 ± 0.01. CFMU-Glu could be used for sensitive monitoring of the almond βGLU and Enterococcus faecalis (E. faecalis) at the optimal pHs of 6.50 and 7.00, resp. Moreover, a new sensitive and selective fluorogenic broth (PBF-B) for E. faecalis, utilizing CFMU-Glu and polymyxin B, was also developed. Polymyxin B was discovered to can significantly improve the detection selectivity and signal intensity. The proposed 4-four method using PBF-B and a microcentrifuge tube could provide fluorogenic detection limits of 5.01 x 10⁴ and 1.0 x 10⁵ CFU mL^-1 by fluorescence microplate reader and naked eye, resp.; it could also provide a turn-on chromogenic detection limit of 1.0 x 10⁶ CFU mL^-1 by naked eye. The proposed method could detect 8 CFU mL^-1 of E. faecalis in drinking water, Liangcha (herbal tea) and milk samples within 10 h, without pre-enrichment. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Computed Properties of C6H5ClO2).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Computed Properties of C6H5ClO2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Reductive oxyamination: a method for the qualitative and quantitative analysis of monosaccharides with a new aminooxy reagent using high-performance liquid chromatography with fluorescence detection was written by Ding, Manman;Guan, Zhaobing;Cai, Hongwei;Huang, Yiyong;Lin, Yawei;Hu, Xiaosong. And the article was included in Analytical and Bioanalytical Chemistry in 2018.COA of Formula: C6H5ClO2 The following contents are mentioned in the article:

Derivatization of carbohydrates with aminooxy agents to form oximes can be used for qual. and quant. anal. of carbohydrates; however, the formation of isomeric products limits its application. A new reductive oxyamination procedure developed for the anal. of monosaccharides with a novel fluorescent O-substituted aminooxy reagent, 4-((aminooxy)methyl)-6-chloro-7-hydroxycoumarin (AOCC), is reported. In this procedure, monosaccharides undergo an oxime formation reaction with AOCC and are then readily reduced with 2-picoline-borane, followed by anal. with HPLC with fluorescence detection. Good separation of five monosaccharide derivatives was achieved within 40 min with acetonitrile-water-tetrahydrofuran as the mobile phase. The detection limits were on the order of femtomoles. The linear range was 0.2-4000 nM, with a good correlation coefficient (R ≥ 0.9985). Furthermore, the method was applied for anal. of real samples, such as bovine milk powder, without complicated and tedious sample treatment. This reductive oxyamination method circumvents the problem caused by oxime isomers and can be used for the highly sensitive and selective anal. of monosaccharides with high accuracy, providing an effective and promising method for the anal. of carbonyls with aminooxy agents. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5COA of Formula: C6H5ClO2).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.COA of Formula: C6H5ClO2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Performance and Mechanism of Piezo-Catalytic Degradation of 4-Chlorophenol: Finding of Effective Piezo-Dechlorination was written by Lan, Shenyu;Feng, Jinxi;Xiong, Ya;Tian, Shuanghong;Liu, Shengwei;Kong, Lingjun. And the article was included in Environmental Science & Technology in 2017.Electric Literature of C6H5ClO2 The following contents are mentioned in the article:

Piezo-catalysis was first used to degrade a non-dye pollutant, 4-chlorophenol (4-CP). In this process, hydrothermally synthesized tetragonal BaTiO3 nano/μm-sized particles were used as the piezo-catalyst and the ultrasonic irradiation with low frequency was selected as the vibration energy to cause the deformation of tetragonal BaTiO3. It was found that the piezoelec. potential from the deformation could not only successfully degrade 4-chlorophenol, but also effectively make it dechlorination at the same time. And five kinds of dechlorinated intermediates, hydroquinone, benzoquinone, phenol, cyclohexanone, cyclohexanol, were determined This is the first sample of piezo-dechlorination. Although various active species, including h+,e-, •H, •OH, O₂•^-1, O₂ and H₂O₂, were generated in the piezoelec. process, it was confirmed by ESR, scavenger studies and LC-MS that the degradation and dechlorination were mainly attributed to •OH radicals. These •OH radicals was chiefly derived from the electron reduction of O₂, partly from the hole oxidation of H₂O. These results indicated that the piezo-catalysis was an emerging and effective advanced oxidation technol. for degradation and dechlorination of organic pollutants. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Electric Literature of C6H5ClO2).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Chlorination modifies the physical properties of hydrocarbons in several ways. These compounds are typically denser than water due to the higher atomic weight of chlorine versus hydrogen. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Electric Literature of C6H5ClO2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Estimation of the toxicity of different substituted aromatic compounds to the aquatic ciliate Tetrahymena pyriformis by QSAR approach was written by Luan, Feng;Wang, Ting;Tang, Lili;Zhang, Shuang;Cordeiro, M. Natalia Dias Soeiro. And the article was included in Molecules in 2018.SDS of cas: 95-88-5 The following contents are mentioned in the article:

Nowadays, quant. structure-activity relationship (QSAR) methods have been widely performed to predict the toxicity of compounds to organisms due to their simplicity, ease of implementation, and low hazards. In this study, to estimate the toxicities of substituted aromatic compounds to Tetrahymena pyriformis, the QSAR models were established by the multiple linear regression (MLR) and radial basis function neural network (RBFNN). Unlike other QSAR studies, according to the difference of functional groups (-NO₂, -X), the whole dataset was divided into three groups and further modeled sep. The statistical characteristics for the models are obtained as the following: MLR: n = 36, R² = 0.829, RMS (root mean square) = 0.192, RBFNN: n = 36, R² = 0.843, RMS = 0.167 for Group 1; MLR: n = 60, R² = 0.803, RMS = 0.222, RBFNN: n = 60, R² = 0.821, RMS = 0.193 for Group 2; MLR: n = 31 R² = 0.852, RMS = 0.192; RBFNN: n = 31, R² = 0.885, RMS = 0.163 for Group 3, resp. The results were within the acceptable range, and the models were found to be statistically robust with high external predictivity. Moreover, the models also gave some insight on those characteristics of the structures that most affect the toxicity. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5SDS of cas: 95-88-5).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Alkyl chlorides are versatile building blocks in organic chemistry. While alkyl bromides and iodides are more reactive, alkyl chlorides tend to be less expensive and more readily available.SDS of cas: 95-88-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Syntheses, Biological Evaluations, and Mechanistic Studies of Benzo[c][1,2,5]oxadiazole Derivatives as Potent PD-L1 Inhibitors with In Vivo Antitumor Activity was written by Liu, Liu;Yao, Zhiying;Wang, Shijun;Xie, Tao;Wu, Guoqing;Zhang, Honghan;Zhang, Pu;Wu, Yaojun;Yuan, Haoliang;Sun, Hongbin. And the article was included in Journal of Medicinal Chemistry in 2021.Recommanded Product: 4-Chlororesorcinol The following contents are mentioned in the article:

A series of novel benzo[c][1,2,5]oxadiazole derivatives were designed, synthesized, and biol. evaluated as inhibitors of PD-L1. Among them, compound I [R = H] exhibited 1.8 nM IC₅₀ value in a homogeneous time-resolved fluorescence (HTRF) assay, which was 20-fold more potent than the lead compound BMS-1016 (II). In the surface plasmon resonance (SPR) assay, compound I [R = H] bound to human PD-L1 (hPD-L1) with a K_D value of 3.34 nM, without showing any binding to hPD-1. In the cell-based coculture assay, compound I [R = H] blocked PD-1/PD-L1 interaction with an EC₅₀ value of 375 nM, while BMS-1016 had an EC₅₀ value of 2075 nM. Moreover, compound I [R = Et] , an ester prodrug of compound I [R = H], was orally bioavailable and displayed significant antitumor effects in tumor models of syngeneic and PD-L1 humanized mice. Mechanistically, compound I [R = Et] exhibited significant in vivo antitumor effects probably through promoting antitumor immunity. Together, this series of benzoxadiazole PD-L1 inhibitors holds promise for tumor immunotherapy. Preclin. trials with selected compounds are ongoing in our laboratory This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Recommanded Product: 4-Chlororesorcinol).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Recommanded Product: 4-Chlororesorcinol

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Mitochondrial-targeted near-infrared fluorescence probe for selective detection of fluoride ions in living cells was written by Xu, Xiaobo;Chen, Wen;Yang, Mei;Liu, Xian-Jun;Wang, Fenglin;Yu, Ru-Qin;Jiang, Jian-Hui. And the article was included in Talanta in 2019.Product Details of 95-88-5 The following contents are mentioned in the article:

Fluoride ions (F^–), as a strongest electron withdrawing anion of the smallest size, have played an indispensable role in biol. systems. Here a mitochondria-targeted near-IR (NIR) fluorescent probe (Mito-FP) is developed for selective detection of F^– in living cells. Mito-FP is designed using a NIR hemicyanine as a fluorophore and tert-butyldimethylsilyl (TBDMS) as a recognition site which is linked to the fluorophore via a 4-hydroxylbenzyl alc. self-immolative linker. Mito-FP is essentially nonfluorescent. F^– can specifically cleave the Si-O bond which triggers the elimination of the quinone methide intermediate and generates the initial NIR hemicyanine fluorophore with distinct intramol. charge transfer and activated fluorescence signal. The Mito-FP probe is responsive to the concentrations of F^– in the range of 10-120μM with an estimated limit of detection of 3.2μM. Mito-FP also exhibits high selectivity toward F^– with good stability in the physiol. pH conditions. Mito-FP is successfully introduced to detect and image F^– in HeLa cells. Moreover, Mito-FP is also demonstrated to exhibit excellent mitochondrial-targeting ability. This NIR fluorescence probe could provide a useful tool for studying F^– in mitochondria. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Product Details of 95-88-5).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. An organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Product Details of 95-88-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Radiolytic degradation of chlorobenzene in aerated and deoxygenated aqueous solutions was written by Albarran, Guadalupe;Mendoza, Edith. And the article was included in Environmental Science and Pollution Research in 2020.Quality Control of 4-Chlororesorcinol The following contents are mentioned in the article:

Abstract: Radiation-induced degradation of chlorobenzene was conducted at 0.1, 0.4, 0.5, 0.7, and 1.0 mmol/dm³ concentrations in aerated environment and at 1.0 mmol/dm³ in oxygen-free and N₂O-saturated solutions The results demonstrated that the elimination of chloride is important when the solution is oxygen free, because the e^–aq attacks at the ipso position of the chloro group produces hydrochloric acid. The degradation was affected to a large extent by the concentration and to a lesser extent by the presence or absence of oxygen in the solutions which were irradiated. Thereby, the degradation occurred faster in the solutions with air and without oxygen and more slowly in the saturated solution with N₂O. Some byproducts were identified using an HPLC-UV-mass system. In addition, it was found that there is a linear correlation between the ln C/C₀ and the dose, indicating that the radiolytic degradation followed pseudo-first-order reaction kinetics. The radiolytic oxidation was followed by the COD (COD) test. The COD decreases when the solute concentration increases. The COD results were for a 0.47 mmol/dm³ of 5.94 mg O₂ dm^-3 kGy^-1 and for 0.09 mmol/dm³ of 7.45 mg O₂ dm^-3 kGy^-1. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Quality Control of 4-Chlororesorcinol).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Organochlorines are organic compounds having multiple chlorine atoms. They were the first synthetic pesticides that were used in agriculture. They are resistant to most microbial and chemical degradations. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Quality Control of 4-Chlororesorcinol

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Octadecylamine and glucose-coderived hydrophobic carbon dots-modified porous silica for chromatographic separation was written by Chen, Jia;Yuan, Ning;Jiang, Danni;Lei, Qian;Liu, Bei;Tang, Weiyang;Row, Kyung Ho;Qiu, Hongdeng. And the article was included in Chinese Chemical Letters in 2021.Application In Synthesis of 4-Chlororesorcinol The following contents are mentioned in the article:

A Hydrophobic carbon dots (Glc-OCDs) derived from octadecylamine and glucose were successfully synthesized for the first time and then grafted onto the porous silica surface by the “Nano-on-Micro” strategy, which was served as a new stationary phase (Sil-Glc-OCDs) for reversed-phase liquid chromatog. The structure of this stationary phase was carefully verified by laser scanning confocal microscope, Fourier transform IR spectrometry, elemental anal., contact angle measurement, etc. Several analytes including seven polycyclic aromatic hydrocarbons, eight alkylbenzenes, eight phenols and seven sulfonamides can be well separated on this stationary phase. Better separation performance for certain analytes over com. C₁₈ column was obtained. Interestingly, this stationary phase exhibited excellent chromatog. selectivity in the separation of the isomers of tert-butylbenzene, sec-butylbenzene, isobutylbenzene and n-butylbenzene. In addition, this new Sil-Glc-OCDs column was also applied for detection of calycosin-7-glucoside, ononin, calycosin, formononetin, genistein and isorhamnetin in the extract of Radix Astragali, which were found that the concentration was 0.15 g/L, 0.088 g/L, 0.14 g/L, 0.086 g/L, 0.18 g/L and 0.29 g/L, resp. We believe that this CDs-grafted silica materials are promising for chromatog. separation This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Application In Synthesis of 4-Chlororesorcinol).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Application In Synthesis of 4-Chlororesorcinol

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

An activatable ratiometric near-infrared fluorescent probe for hydrogen sulfide imaging in vivo was written by Wu, Luyan;Zeng, Wenhui;Feng, Liandong;Hu, Yuxuan;Sun, Yidan;Yan, Yingxiao;Chen, Hong-Yuan;Ye, Deju. And the article was included in Science China: Chemistry in 2020.Formula: C6H5ClO2 The following contents are mentioned in the article:

Ratiometric fluorescent probes hold great promise for in vivo imaging; however, stimuli-activatable ratiometric probes with fluorescence emissions in near-IR (NIR) region are still very few. Herein, we report a hydrogen sulfide (H₂S)-activatable ratiometric NIR fluorescent probe (1-SPN) by integrating a H₂S-responsive NIR fluorescent probe 1 into a H₂S-inert poly[2,6-(4,4-bis-(2-ethylhexyl)-4H-cyclopenta[2,1-b;3,4-b’]dithiophene)-alt-4,7(2,1,3-benzothiadiazole)] (PCPDTBT)-based NIR semiconducting polymer nanoparticle (SPN). 1-SPN shows “always on” PCPDTBT fluorescence at 830 nm and weak probe 1 fluorescence at 725 nm under excitation at 680 nm. The ratio of NIR fluorescence intensities between 725 and 830 is small. Upon interaction with H₂S, the fluorescence at 725 nm is rapidly switched on, resulting in a large enhancement of I₇₂₅/I₈₃₀, which is allowed for sensitive visualization and quantification of H₂S concentrations in living cells. Taking advantage of enhanced tissue penetration depth of NIR fluorescence, 1-SPN is also applied for real-time ratiometric fluorescence imaging of hepatic and tumor H₂S in living mice. This study demonstrates that activatable ratiometric NIR fluorescent probes hold great potential for in vivo imaging. This study involved multiple reactions and reactants, such as 4-Chlororesorcinol (cas: 95-88-5Formula: C6H5ClO2).

4-Chlororesorcinol (cas: 95-88-5) belongs to organic chlorides. Organochlorines stimulate the central nervous system and cause convulsions, tremor, nausea, and mental confusion. Examples are dichlorodiphenyltrichloroethane (DDT), chlordane, lindane, endosulfan, and dieldrin. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control.Formula: C6H5ClO2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics