Category: 98-60-2

Recommanded Product: 98-60-2In 2021 ,《Regio- and stereoselective electrochemical synthesis of sulfonylated enethers from alkynes and sulfonyl hydrazides》 was published in Green Chemistry. The article was written by Du, Wu-Bo; Wang, Ning-Ning; Pan, Chao; Ni, Shao-Fei; Wen, Li-Rong; Li, Ming; Zhang, Lin-Bao. The article contains the following contents:

An electrooxidative direct difunctionalization of internal alkynes RCCR1 [R = Ph, 2-chlorophenyl, thiophen-2-yl, etc.; R1 = Me, cyclopropyl, 2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)ethyl, etc.] with sulfonyl hydrazides R2S(O)2NHNH2 (R2 = 4-methylphenyl, 3-bromophenyl, cyclopropyl, etc.) has been developed for the construction of sulfonated enethers (E)-RC(OR3)=C(R1)S(O)2R2 (R3 = Et, 2,2,2-trifluoroethyl, cyclohexyl, etc.). In this transformation, metal catalysts or stoichiometric amount of oxidants are not required and mol. nitrogen and hydrogen are the sole byproducts, providing a simple and green approach for preparing various sulfonyl tetrasubstituted alkenes. Notably, the protocol could be efficiently scaled up and the follow-up procedures of the corresponding functionalized alkenes demonstrate the practicality of the electrochem. synthesis. In the part of experimental materials, we found many familiar compounds, such as 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Recommanded Product: 98-60-2)

4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Recommanded Product: 98-60-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Category: chlorides-buliding-blocksIn 2019 ,《Regioselective Sulfonylvinylation of the Unactivated C(sp3)-H Bond via a C-Centered Radical-Mediated Hydrogen Atom Transfer (HAT) Process》 appeared in Organic Letters. The author of the article were Yang, Shan; Wu, Xinxin; Wu, Shuo; Zhu, Chen. The article conveys some information:

Given the similarity of multiple sp3 C-H bonds in electronic properties and bond dissociation energy (BDE), regioselective sp3 C-H bond functionalization remains a paramount challenge. Here, the authors report a C-centered radical-mediated approach for site-specific sulfonylvinylation of the C(sp3)-H bond via the hydrogen atom transfer (HAT) process. The reaction features mild conditions, broad substrate scope, and high regioselectivity and stereoselectivity, manifesting the nontrivial synthetic potential. In the experimental materials used by the author, we found 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Category: chlorides-buliding-blocks)

4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. Many organochlorine compounds have been isolated from natural sources ranging from bacteria to humans. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Xu, Yi-Xin; Liang, Yu-Qing; Cai, Zhong-Jian; Ji, Shun-Jun published an article in 2022. The article was titled 《Ruthenium(II)-Catalyzed Chelation-Assisted Desulfitative Arylation of Benzo[h]quinolines with Arylsulfonyl Chlorides》, and you may find the article in Organic Letters.Related Products of 98-60-2 The information in the text is summarized as follows:

Herein, a novel chelation-assisted C-H arylation reaction of benzo[h]quinoline is described. This transformation, using [RuCl2(p-cymene)]2 as the catalyst and cheap and easily accessible arylsulfonyl chlorides as the arylation source, featured simple reaction conditions, a broad substrate scope, and functional group tolerance. The successful application of some bioactive-mol.-based sulfonyl chlorides further highlighted the potential utility and importance of this desulfitative C-H arylation protocol. In the experiment, the researchers used 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Related Products of 98-60-2)

4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Related Products of 98-60-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Yang, Shan; Liu, Lingling; Zhou, Zheng; Huang, Zhibin; Zhao, Yingsheng published their research in Organic Letters in 2021. The article was titled 《Palladium-Catalyzed Direct C-H Arylation of 3-Butenoic Acid Derivatives》.Electric Literature of C6H4Cl2O2S The article contains the following contents:

Herein a direct method to synthesize 4-aryl-3-butenoic acid through a carboxylic-acid-directed oxidative Heck reaction is reported. The various 4-aryl-3-butenoic acids are easily prepared in moderate to good yields. In view of the promising bioactivity of 4-phenyl-3-butenoic acid previously reported, its derivatives reported here may be bioactive. In the experiment, the researchers used 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Electric Literature of C6H4Cl2O2S)

4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. Many organochlorine compounds have been isolated from natural sources ranging from bacteria to humans. Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids. Electric Literature of C6H4Cl2O2S

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

COA of Formula: C6H4Cl2O2SIn 2022 ,《Electrochemically-promoted synthesis of benzo[b]thiophene-1,1-dioxides via strained quaternary spirocyclization》 was published in Chemical Science. The article was written by Li, Ruitao; Yuan, Dafu; Ping, Mengqi; Zhu, Yuyi; Ni, Shaofei; Li, Ming; Wen, Lirong; Zhang, Lin-Bao. The article contains the following contents:

An approach for the synthesis of benzothiophene motifs under electrochem. conditions by the reaction of sulfonhydrazides with internal alkynes was reported. Upon the formation of a quaternary spirocyclization intermediate by the selective ipso-addition instead of an ortho-attack, the S-migration process was rationalized to lead to the products. Computational studies revealed the selectivity and the compatibility of drug mols. showcased the potential application of the protocols. In the experiment, the researchers used 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2COA of Formula: C6H4Cl2O2S)

4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.COA of Formula: C6H4Cl2O2S

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chen, Dan; Lin, Li; Peng, Xiaoyan; Yu, Xinyi; Yang, Zhonglie; Liu, Yutong; Zhang, Xiaobin; Li, Jiahong; Jiang, Hezhong published their research in Tetrahedron Letters in 2021. The article was titled 《Transition-metal-free NaI-mediated reaction of aryl sulfonyl chloride with alkynes: Synthesis of (E)-β-iodovinyl sulfones》.Electric Literature of C6H4Cl2O2S The article contains the following contents:

A novel protocol for synthesis of (E)-β-iodovinyl sulfones via NaI-mediated aryl sulfonyl chloride with alkynes were described, featuring transition-metal-free condition, com. available substrates, convenient operation, as well as good functional group compatibility. A wide variety of substrate application and good functional group tolerance were provided by this approach, giving multiple (E)-β-iodovinyl sulfones analogs with excellent yields (up to 98%, >4 g scale).4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Electric Literature of C6H4Cl2O2S) was used in this study.

4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties.Electric Literature of C6H4Cl2O2S Organochlorine compounds have wide use in many applications, though some are of profound environmental concern, with TCDD being one of the most notorious.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Copper-Catalyzed Trifluoromethylation/Cyclization of Alkynes for Synthesis of Dioxodibenzothiazepines》 was written by Zhang, Zi-Qi; Xu, Yi-Hao; Dai, Jing-Cheng; Li, Yan; Sheng, Jie; Wang, Xi-Sheng. Application In Synthesis of 4-Chlorobenzenesulfonyl chlorideThis research focused ontrifluoroethylidene dioxodibenzothiazepine regioselective diastereoselective preparation; ethynylphenyl benzenesulfonamide Tognis reagent copper trifluromethylation tandem radical cyclization. The article conveys some information:

A facile and efficient approach for the synthesis of the CF3-containing dioxodibenzothiazepines was developed via copper-catalyzed trifluoromethylation/cyclization of alkynes utilizing a radical relay strategy. This method showed demonstrated low catalyst loading, high regiocontrol and broad scope under mild conditions. Good compatibility for the N-protecting group, gram-scale experiment, and further derivation of product proved the versatility of this transformation. In the part of experimental materials, we found many familiar compounds, such as 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Application In Synthesis of 4-Chlorobenzenesulfonyl chloride)

4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Application In Synthesis of 4-Chlorobenzenesulfonyl chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Yuan, Kedong; Feoktistova, Taisiia; Cheong, Paul Ha-Yeon; Altman, Ryan A. published their research in Chemical Science in 2021. The article was titled 《Arylation of gem-difluoroalkenes using a Pd/Cu Co-catalytic system that avoids β-fluoride elimination》.Application In Synthesis of 4-Chlorobenzenesulfonyl chloride The article contains the following contents:

PdII/CuI co-catalyze an arylation reaction of gem-difluoroalkenes using arylsulfonyl chlorides to deliver α,α-difluorobenzyl products. The reaction proceeded through a β,β-difluoroalkyl-Pd intermediate that typically underwent unimol. β-F elimination to deliver monofluorinated alkene products in a net C-F functionalization reaction. However to avoid β-F elimination, the β,β-difluoroalkyl-Pd intermediate were offered, an alternate low-energy route involving β-H elimination to ultimately deliver difluorinated products in a net arylation/isomerization sequence. Overall, this reaction enabled exploration of new reactivities of unstable fluorinated alkyl-metal species, while also providing new opportunities for transforming readily available fluorinated alkenes into more elaborate substructures. The experimental part of the paper was very detailed, including the reaction process of 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Application In Synthesis of 4-Chlorobenzenesulfonyl chloride)

4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. Many organochlorine compounds have been isolated from natural sources ranging from bacteria to humans. Application In Synthesis of 4-Chlorobenzenesulfonyl chloride Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《CuCl2-promoted decomposition of sulfonyl hydrazides for the synthesis of thiosulfonates》 was written by Kim, Junsu; Park, Sanggil; Kim, Hyungjun; Kim, Jinho. Application In Synthesis of 4-Chlorobenzenesulfonyl chlorideThis research focused onthiosulfonate preparation copper catalyst; sulfonyl hydrazide decomposition. The article conveys some information:

Sulfonyl hydrazides recently received much attention as reagents for the introduction of sulfur-containing functional groups into organic compounds, because both sulfonyl and sulfenyl sources could be generated by the oxidation and decomposition of the sulfonyl hydrazides, resp. However, the transformations of sulfonyl hydrazides into thiosulfonates, which could be produced by the reaction between sulfonyl and sulfenyl sources, have been less investigated. In this manuscript, CuCl2-promoted selective synthesis of thiosulfonates I (R = 4-Me, 4-NO2, 3-Br, 2-Naph, etc.) from sulfonyl hydrazides is described. A variety of thiosulfonates were produced in moderate to good yields. The mechanism involving radical intermediates such as sulfonyl radical and thiyl radical was proposed on the basis of the previously reported references and mechanistic investigations. In addition, quantum chem. simulations revealed that Cu-promoted decomposition of sulfonyl hydrazides is thermodynamically viable in the developed conditions. In addition to this study using 4-Chlorobenzenesulfonyl chloride, there are many other studies that have used 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Application In Synthesis of 4-Chlorobenzenesulfonyl chloride) was used in this study.

4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. Application In Synthesis of 4-Chlorobenzenesulfonyl chloride The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Huo, Yong-Wang; Qi, Xinxin; Wu, Xiao-Feng published an article in 2022. The article was titled 《Nickel-Catalyzed Carbonylative Synthesis of α,β-Unsaturated Thioesters from Vinyl Triflates and Arylsulfonyl Chlorides》, and you may find the article in Organic Letters.Electric Literature of C6H4Cl2O2S The information in the text is summarized as follows:

A straightforward and efficient synthesis of α,β-unsaturated thioesters RC(O)SR1 [R = cyclopenten-1-yl, cyclohexen-1-yl, 3,4-dihydronaphthalen-1-yl, etc.; R1 = 4-MeC6H4, 4-FC6H4, 4-MeOC6H4, etc.] had been developed via a nickel-catalyzed thiocarbonylation reaction of vinyl triflates with arylsulfonyl chlorides. With Mo(CO)6 as both CO source and reductant, a variety of α,β-unsaturated thioesters were obtained in moderate to good yields with very good functional group compatibility. It was noteworthy that the present method was the first example on nickel-catalyzed carbonylative synthesis of α,β-unsaturated thioesters by using arylsulfonyl chlorides as the coupling partner. In the part of experimental materials, we found many familiar compounds, such as 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Electric Literature of C6H4Cl2O2S)

4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.Electric Literature of C6H4Cl2O2S

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics