Category: 98-60-2

Yuan, Zhi-ying; Zhang, Shuai; Teng, Fan; Jin, Xue-Feng; Sheng, Wen-bing; Gui, Qing-Wen published an article in 2022. The article was titled 《Iodide Salt Mediated Synthesis of β-Keto Sulfones Using Arylsulfonyl Chlorides as the Sulfur Sources》, and you may find the article in ChemistrySelect.Recommanded Product: 98-60-2 The information in the text is summarized as follows:

An efficient, green strategy was developed to synthesize β-keto sulfones using available and inexpensive sulfonyl chlorides as a sulfur source in reaction with aromatic alkenes in the presence of cheap iodide. It was particularly pointed out that this method involved the construction of C-S bonds and the desired product can be obtained either through the free radical pathway. This agreement involved a green and simple synthesis method, and was functionalized with styrene and the present method is applicable to a wide range of benzenesulfonyl chloride compounds and styrenes with a variety of functional groups. In the experiment, the researchers used 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Recommanded Product: 98-60-2)

4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. Many organochlorine compounds have been isolated from natural sources ranging from bacteria to humans. Recommanded Product: 98-60-2 Chlorinated organic compounds are found in nearly every class of biomolecules and natural products including alkaloids, terpenes, amino acids, flavonoids, steroids, and fatty acids.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Electrochemical Annulation-Iodosulfonylation of 1,5-Enyne-containing para-Quinone Methides (p-QMs) to Access (E)-Spiroindenes》 was written by Zuo, Hang-Dong; Hao, Wen-Juan; Zhu, Chi-Fan; Guo, Cheng; Tu, Shu-Jiang; Jiang, Bo. Product Details of 98-60-2 And the article was included in Organic Letters in 2020. The article conveys some information:

A new electrochem. three-component annulation-iodosulfonylation of 1,5-enyne-containing para-quinone methides (p-QMs) has been established by using available arylsulfonyl hydrazides and potassium iodide under environmentally benign conditions. The electrosynthesis offers sustainable and efficient access to construct spirocyclohexadienone-containing (E)-indenes without any addnl. catalyst or oxidant through a sulfonyl-radical-triggered 1,6-addition and an I+-mediated ipso-cyclization cascade. Notably, potassium iodide plays the triple role of an electrolyte, a redox catalyst, as well as an iodination reagent. The experimental part of the paper was very detailed, including the reaction process of 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Product Details of 98-60-2)

4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Product Details of 98-60-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《A general and practical sulfonylation of benzylic ammonium salts with sulfonyl hydrazides for the synthesis of sulfones》 was published in Tetrahedron Letters in 2020. These research results belong to Zhu, Haibo; Zhang, Yingying; Liu, Yishuai; Yang, Liu; Xie, Zongbo; Jiang, Guofang; Le, Zhang-Gao. Recommanded Product: 4-Chlorobenzenesulfonyl chloride The article mentions the following:

A practical and efficient approach adopting transition-metal-free cross-coupling of sulfonyl hydrazides with benzyl ammonium salts was developed to synthesize benzyl sulfones using Cs2CO3 as base under mild conditions. The protocol employed stable and easy to handle coupling partners, and was endowed with good substrate compatibility, leading to functional benzyl sulfones in good yields. In the experiment, the researchers used many compounds, for example, 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Recommanded Product: 4-Chlorobenzenesulfonyl chloride)

4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. Recommanded Product: 4-Chlorobenzenesulfonyl chloride However, the extent of chlorination is difficult to control. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Ion-Pair Selective Conformational Rearrangement of Sulfonamide Calix[6]arene-Based Pseudorotaxanes》 was written by Cera, Gianpiero; Bazzoni, Margherita; Arduini, Arturo; Secchi, Andrea. Application In Synthesis of 4-Chlorobenzenesulfonyl chlorideThis research focused ontrisulfonamide calixarene viologen ion pair pseudorotaxane conformation. The article conveys some information:

We describe the synthesis of a new class of trisulfonamide calix[6]arene-based wheels that can bind dialkylviologen salts, in apolar media. The threading process occurs through a selective ion-pair recognition, established by the sulfonamide groups with the counterions of the bipyridinium salts, that dictates a conformational rearrangement of the corresponding pseudorotaxanes. In the experiment, the researchers used many compounds, for example, 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Application In Synthesis of 4-Chlorobenzenesulfonyl chloride)

4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. Application In Synthesis of 4-Chlorobenzenesulfonyl chloride The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Safety of 4-Chlorobenzenesulfonyl chlorideIn 2019 ,《Direct coupling of haloquinolines and sulfonyl chlorides leading to sulfonylated quinolines in water》 was published in Tetrahedron Letters. The article was written by Bao, Pengli; Wang, Leilei; Liu, Qishun; Yang, Daoshan; Wang, Hua; Zhao, Xiaohui; Yue, Huilan; Wei, Wei. The article contains the following contents:

A simple and efficient method has been developed for construction of sulfonylated quinolines via coupling of haloquinolines and sulfonyl chlorides in water [e.g., 2-chloroquinoline + tosyl chloride → 2-tosylquinoline (93%, 89% isolated) using Zn powder as reductant at 80° in water]. The present methodol. provides an attractive approach to various sulfonylated quinolines in moderate to good yields with favorable functional group tolerance, which has the advantages of operation simplicity, readily available starting materials, excellent regioselectivity, scale-up synthesis, and organic solvent-free conditions. The experimental process involved the reaction of 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Safety of 4-Chlorobenzenesulfonyl chloride)

4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties. Aliphatic organochlorides are often alkylating agents as chlorine can act as a leaving group, which can result in cellular damage.Safety of 4-Chlorobenzenesulfonyl chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Application of 98-60-2In 2021 ,《Synthesis of symmetrical / unsymmetrical thiosulfonates through the disproportionate coupling reaction of sulfonyl hydrazide mediated by phosphomolybdic acid》 was published in Tetrahedron Letters. The article was written by Lv, Mengting; Liu, Yufeng; Li, Ke; Yang, Guoping. The article contains the following contents:

Phosphomolybdic acid (H3PMo12O40) was reported as a green low-cost catalyst for the synthesis of sym. / unsym. thiosulfonates via the disproportionate coupling reaction of sulfonyl hydrazide. The attributes of this reported catalytic system included low catalyst loadings (1 mol%), efficient turnover, and high yields (up to 94%). Addnl., this reaction mechanism involved the formation of a thiyl radical and sulfonyl radical via sulfinyl radical disproportionation. In the experiment, the researchers used many compounds, for example, 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Application of 98-60-2)

4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. Application of 98-60-2 The haloform reaction, using chlorine and sodium hydroxide, is also able to generate alkyl halides from methyl ketones, and related compounds. Chloroform was formerly produced thus.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Synthesis and biological evaluation of imidazo[2,1-b]thiazole based sulfonyl piperazines as novel carbonic anhydrase II inhibitors》 was written by Manasa, Kesari Lakshmi; Pujitha, Sravya; Sethi, Aaftaab; Arifuddin, Mohammed; Alvala, Mallika; Angeli, Andrea; Supuran, Claudiu T.. Application of 98-60-2 And the article was included in Metabolites in 2020. The article conveys some information:

A novel series of imidazo[2,1-b]thiazole-sulfonyl piperazine conjugates I [R = H, 4-Me, 4-F, 4-MeO, 4-Cl; R1 = H, 4-Me, 4-MeO, 4-Cl, 4-(CH3)3C] synthesized and evaluated for carbonic anhydrase (CA, EC 4.2.1.1) inhibitory potency against four isoforms: The cytosolic isoenzyme hCA I, II and trans-membrane tumor-associated isoform hCA IX and hCA XII, taking acetazolamide (AAZ) as standard drug, using a stopped flow CO2 hydrase assay. The results revealed that most of the compounds showed selective activity against hCA II whereas none of them were active against hCA I, IX, XII (Ki > 100μM). The physiol. dominant cytosolic isoform hCA II was inhibited by these mols. with inhibition constants in the range of 57.7-98.2μM. This new derivative I, thus, selectively inhibited hCA II over the hCA I, IX, XII isoforms, which may be used for further understanding the physiol. roles of some of these isoforms in various pathologies. The results came from multiple reactions, including the reaction of 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Application of 98-60-2)

4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. However, the extent of chlorination is difficult to control. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.Application of 98-60-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

In 2022,Suraj; Swamy, K. C. Kumara published an article in Journal of Organic Chemistry. The title of the article was 《Ring-Expansion Reactions of Epoxy Amides and Enamides: Functionalized Azetidines, Dihydrofurans, Diazocanes, or Dioxa-3-azabicyclonon-4-enes?》.Reference of 4-Chlorobenzenesulfonyl chloride The author mentioned the following in the article:

Functionalized azetidines I [R1 = Ph, 4-MeC6H4, 2-naphthyl, etc.; R2 = Ph, 2-BrC6H4, 2-IC6H4, etc.], 2,3-dihydrofurans II [R3 = Ph, 4-MeC6H4, 4-ClC6H4, etc.] or the unorthodox dioxa-3-azabicyclonone-4-ene motifs III [R4 = Ph, 4-BrC6H4, 2-naphthyl, etc.; R5 = Ph, 4-MeC6H4, 2-BrC6H4, etc.] were the products from transition metal-free reaction between N-oxiranylmethyl benzenesulfonamide and β-chloro-cinnamaldehyde, depending on whether one uses either NaI/K2CO3 or LiBr/K2CO3. These ring expansion reactions involved enamide (X-ray evidence) derived from N-oxiranylmethyl benzenesulfonamide and β-chloro-cinnamaldehyde as an intermediate. The N-oxiranylmethyl benzenesulfonamide itself upon heating gave readily separable and crystalline isomeric diazocanes that could be characterized by X-ray crystallog. In the part of experimental materials, we found many familiar compounds, such as 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Reference of 4-Chlorobenzenesulfonyl chloride)

4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. Alkanes and aryl alkanes may be chlorinated under free radical conditions, with UV light. Reference of 4-Chlorobenzenesulfonyl chloride However, the extent of chlorination is difficult to control. Aryl chlorides may be prepared by the Friedel-Crafts halogenation, using chlorine and a Lewis acid catalyst.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Su, Shijun; Zhou, Qing; Tang, Xuemei; Peng, Feng; Liu, Tingting; Liu, Liwei; Xie, Chengwei; He, Ming; Xue, Wei published their research in Monatshefte fuer Chemie in 2021. The article was titled 《Design, synthesis, and antibacterial activity of novel myricetin derivatives containing sulfonate》.Application of 98-60-2 The article contains the following contents:

A series of myricetin derivatives containing sulfonate groups I (R = Ph, 2-chlorophenyl, 2-thienyl, etc.) was designed and synthesized. Preliminary antibacterial activity showed that most of the target compounds I exhibited significant biol. activities against Xanthomonas axonopodis pv. In particular, the EC50 value of compound I (R = 4-nitrophenyl) was 13.76μg/cm3 against Xac, which was better than com. reagents bismerthiazol (50.32μg/cm3) and thiodiazole copper. (83.27μG/cm3), and the EC50 value of compound I (3-chlorophenyl) was 11.92μg/cm3 against Xoo in vitro and the result was better than that of bismerthiazol (72.08μg/cm3) and thiodiazole copper (99.26μg/cm3). Compound I (R = 3-chlorophenyl) displayed the better in vivo activity against rice bacterial leaf blight than bismerthiazol and thiodiazole copper. Meanwhile, the antibacterial mechanism of compounds I (R = 4-nitrophenyl) and I (R = 3-chlorophenyl) was studied by scanning electron microscope (SEM). These results suggested that myricetin derivatives containing sulfonate I can be considered as new antibacterial reagents. The results came from multiple reactions, including the reaction of 4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Application of 98-60-2)

4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties. Organochlorine compounds have wide use in many applications, though some are of profound environmental concern, with TCDD being one of the most notorious.Application of 98-60-2

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Name: 4-Chlorobenzenesulfonyl chlorideIn 2022 ,《Atom-economic synthesis of β-ketosulfones based on gold-catalyzed highly regioselective hydration of alkynylsulfones》 was published in Green Chemistry. The article was written by Chikunova, Elena I.; Kukushkin, Vadim Yu.; Dubovtsev, Alexey Yu.. The article contains the following contents:

Gold(I)-catalyzed highly regioselective hydration of alkynylsulfones comprised an efficient 100% atom-economic route to β-ketosulfones. The reaction proceeded under mild mercury-free conditions (Ph3PAuNTf2 0.5-5 mol%, THF, rt or 60°C), it demonstrated a high functional group tolerance (more than 30 examples; yields up to 99%), and was easily scaled up. The developed hydration methodol. were successfully integrated into the one-pot syntheses of valuable heterocycles.4-Chlorobenzenesulfonyl chloride(cas: 98-60-2Name: 4-Chlorobenzenesulfonyl chloride) was used in this study.

4-Chlorobenzenesulfonyl chloride(cas: 98-60-2) belongs to organochlorine compounds. The wide structural variety and divergent chemical properties of organochlorides lead to a broad range of names, applications, and properties.Name: 4-Chlorobenzenesulfonyl chloride Organochlorine compounds have wide use in many applications, though some are of profound environmental concern, with TCDD being one of the most notorious.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics