Category: 99-60-5

On November 1, 2017, Lemmerer, Andreas; Motlaung, Xolani published an article.Reference of 2-Chloro-4-nitrobenzoic acid The title of the article was Stoichiometric and polymorphic salts of hexamethylenetetraminium and 2-chloro-4-nitrobenzoate. And the article contained the following:

Four mol. salts made from hexamethylenetetraminium and 2-chloro-4-nitrobenzoate have been synthesized and are reported, namely ammonium hexamethylenetetraminium bis(2-chloro-4-nitrobenzoate), NH4+·C6H13N4+·2C7H3ClNO4-, (I), hexamethylenetetraminium hydrogen bis(2-chloro-4-nitrobenzoate), 0.5C6H13N4+·C7H3.50ClNO4-, (II), hexamethylenetetraminium 2-chloro-4-nitrobenzoate, C6H13N4+·C7H3ClNO4-, (IIIa) and (IIIb). All four mol. salts show N+-H··O- hydrogen bonding. Salt (I) crystallized out with an NH4+ counter-ion which came from decomposition of 50% of the hexamethylenetetraminium cation in solution (II) shows an unusual asym. unit, with both a hexamethylenetetraminium cation and a partially deprotonated 2-chloro-4-nitrobenzoate anion. Salts (IIIa) and (IIIb) are polymorphs of each other. This work shows that hexamethylenetetramine only protonates once, even in the presence of excess acid. The experimental process involved the reaction of 2-Chloro-4-nitrobenzoic acid(cas: 99-60-5).Reference of 2-Chloro-4-nitrobenzoic acid

The Article related to hexamethylenetetraminium chloro nitrobenzoate stoichiometric polymorphic salt, crystal structure, mol­ecular salts, polymorphs, stoichiometric ratio, Crystallography and Liquid Crystals: Crystal Morphology (Habit), Orientation, Crystallinity and other aspects.Reference of 2-Chloro-4-nitrobenzoic acid

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On February 29, 2020, Karthick, S.; Thirupugalmani, K.; Krishnakumar, M.; Kannan, V.; Vinitha, G.; Brahadeeswaran, S. published an article.Formula: C7H4ClNO4 The title of the article was Synthesis, structural, dielectric, laser damage threshold, third order nonlinear optical and quantum chemical investigations on a novel organic crystalline material: Pyrrolidin-1-ium 2-chloro-4-nitrobenzoate 2-chloro-4-nitrobenzoic acid for opto-electronic applications. And the article contained the following:

It is reported that a novel third order organic nonlinear optical material namely, Pyrrolidin-1-ium 2-chloro-4-nitrobenzoate 2-chloro-4-nitrobenzoic acid (PCNCN) has been synthesized and grown by isothermal solvent evaporation solution growth technique. Single crystal X-ray diffraction anal. revealed that PCNCN belonged to monoclinic crystal system with a centrosym. space group of P21/c. The morphol. of the as grown PCNCN crystal compared well with that obtained by theor. generated morphol. The mol. vibrations of PCNCN were analyzed through Fourier transform IR and NMR spectrum analyses. Optical properties such as transmittance, photoluminescence, and laser damage threshold were studied. The thermal stability of PCNCN was measured through TG-DTA measurement. The dielec. properties such as dielec. constant, dielec. loss, ac conductivity and activation energy of PCNCN single crystal were studied as a function of frequency at different temperatures The PCNCN single crystals were further characterized for their third order nonlinear optical properties such as nonlinear absorption coefficient, nonlinear refractive index and optical limiting behavior using continuous wave Nd: YAG laser. The quantum chem. investigations were performed using B3LYP/6-311++G(d, p) basis set. The experimental process involved the reaction of 2-Chloro-4-nitrobenzoic acid(cas: 99-60-5).Formula: C7H4ClNO4

The Article related to dielec constant laser damage threshold organic crystalline material, Optical, Electron, and Mass Spectroscopy and Other Related Properties: Optical Properties (Linear) and other aspects.Formula: C7H4ClNO4

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On February 28, 2018, Karami, Kazem; Rahimi, Mahzad; Dinari, Mohammad published an article.Category: chlorides-buliding-blocks The title of the article was High catalytic activity of a new Ag phosphorus ylide complex supported on montmorillonite: synthesis, characterization, and application for room temperature nitro reduction. And the article contained the following:

In this work, the phosphorus ylide, [PPh3CHC(O)CH2Cl], was reacted with AgNO3 to give the [Ag{C(H)PPh3C(O)CH2Cl}2]+NO3- as the product. Then, it was supported on the modified montmorillonite nanoclay to prepare a new catalyst for the reduction reaction. The structure and morphol. of the nanoclay catalyst were characterized by FT-IR, X-ray powder diffraction, SEM, energy-dispersive X-ray anal. and transmission electron microscopy techniques; also, the content of silver was obtained by inductively coupled plasma analyzer. This composition was exploited to study its catalytic activity in the reduction in aromatic nitro compounds; it displayed the high catalytic activity. Factors such as catalyst amount, solvent, temperature and reaction time were all systematically investigated to elucidate their effects on the yield of catalytic reduction in nitroarenes. This catalytic system exhibited high activity toward aromatic nitro compounds under mild conditions. The catalyst was reused five times without any significant loss in its catalytic activity. The experimental process involved the reaction of 2-Chloro-4-nitrobenzoic acid(cas: 99-60-5).Category: chlorides-buliding-blocks

The Article related to nitro reduction montmorillonite supported silver phosphorus ylide complex, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On March 15, 2018, Karthick, S.; Thirupugalmani, K.; Shanmugam, G.; Kannan, V.; Brahadeeswaran, S. published an article.Recommanded Product: 2-Chloro-4-nitrobenzoic acid The title of the article was Experimental and quantum chemical studies on N-H—O hydrogen bonded helical chain type Morpholinium 2-chloro-4-nitrobenzoate: A phasematchable organic nonlinear optical material. And the article contained the following:

We report on the studies performed on Morpholinium 2-chloro-4-nitrobenzoate (M2C4N), a second order nonlinear optical (NLO) material, which has been proved to crystallize with chiral structure as compared to its other two variants. The synthesized powder was studied for its composition, crystalline phase and NLO efficiency and phase matchability. The solubility and the metastable zone width (MSZW) of the title compound were measured for the growth of bulk crystals of M2C4N. A smoky pattern observed in the middle region of the crystals that could prevent it from optical applications was greatly reduced, through suitable modifications in the growth process. The optical properties such as luminescence and laser damage threshold resistance were studied for the bulk crystals whereas the mol. vibrations of M2C4N were studied through Fourier transform IR (FTIR) and FT-Raman spectral anal. using the polycrystalline powders derived from the single crystals. In addition, quantum chem. studies on M2C4N mol. were performed by using d. functional theory (DFT) at the B3LYP/6-311++G (d, p) basis set. These studies showed that the M2C4N is a phase matchable NLO crystal and could be used for device fabrication. The experimental process involved the reaction of 2-Chloro-4-nitrobenzoic acid(cas: 99-60-5).Recommanded Product: 2-Chloro-4-nitrobenzoic acid

The Article related to exptl quantum chem nitrogen hydrogen oxygen bonded helical chain, Industrial Organic Chemicals, Leather, Fats, and Waxes: Manufacture Of Industrial Organic Chemicals and other aspects.Recommanded Product: 2-Chloro-4-nitrobenzoic acid

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

On July 16, 2021, Qu, Zhonghua; Chen, Xing; Zhong, Shuai; Deng, Guo-Jun; Huang, Huawen published an article.HPLC of Formula: 99-60-5 The title of the article was NaI/PPh3-Mediated Photochemical Reduction and Amination of Nitroarenes. And the article contained the following:

A mild transition-metal- and photosensitizer-free photoredox system based on the combination of NaI and PPh3 was found to enable highly selective reduction of nitroarenes. This protocol tolerated a broad range of reducible functional groups such as halogen (Cl, Br and even I), aldehyde, ketone, carboxyl and cyano. Moreover, the photoredox catalysis with NaI and stoichiometric PPh3 provides also an alternative entry to Cadogan-type reductive amination when o-nitrobiarenes were used. The experimental process involved the reaction of 2-Chloro-4-nitrobenzoic acid(cas: 99-60-5).HPLC of Formula: 99-60-5

The Article related to chemoselective nitroarene reduction amination photochem, Heterocyclic Compounds (One Hetero Atom): Indoles, Indolizines, Carbazoles, and Other Arenopyrroles and other aspects.HPLC of Formula: 99-60-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chen, Jianxia; Namila, E.; Bai, Chaolumen; Baiyin, Menghe; Bao, Agula; Bao, Yong-Sheng published an article in 2018, the title of the article was Transesterification of (hetero)aryl esters with phenols by an Earth-abundant metal catalyst.COA of Formula: C7H4ClNO4 And the article contains the following content:

Readily available and inexpensive Earth-abundant alkali metal species were used as efficient catalysts for the transesterification of aryl or heteroaryl esters with phenols which is a challenging and underdeveloped transformation. The simple conditions and the use of heterogeneous alkali metal catalyst make this protocol very environmentally friendly and practical. This reaction fills in the missing part in transesterification reaction of phenols and provides an efficient approach to aryl esters, which are widely used in the synthetic and pharmaceutical industry. The experimental process involved the reaction of 2-Chloro-4-nitrobenzoic acid(cas: 99-60-5).COA of Formula: C7H4ClNO4

The Article related to aryl ester preparation green chem, ester preparation phenol alkali metal catalyst transesterification, Benzene, Its Derivatives, and Condensed Benzenoid Compounds: Esters, Acyl Peroxides, Acyl Halides and other aspects.COA of Formula: C7H4ClNO4

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Dhanya, K.; Revanasiddappa, B. C. published an article in 2021, the title of the article was Synthesis and anti-inflammatory activity of novel 1,3,4-oxadiazole derivatives.Category: chlorides-buliding-blocks And the article contains the following content:

A new series of novel 2-R-5-(4-nitrophenyl)-1,3,4-oxadiazoles (R = Ph, 4-H2NC6H4, 2-BrC6H4, etc.) was synthesized by reacting 4-nitrobenzhydrazide and benzoic acids RCO2H in the presence of phosphorus oxychloride. The title compounds were characterized by spectral data (IR, NMR, mass). In-vitro anti-inflammatory activity of all the newly synthesized compounds were evaluated by denaturation assay, anti-proteinase method, HRBC assay, and diclofenac sodium was used as standard drug. Some of the tested compounds showed good anti-inflammatory activity by denaturation assay. The experimental process involved the reaction of 2-Chloro-4-nitrobenzoic acid(cas: 99-60-5).Category: chlorides-buliding-blocks

The Article related to nitrophenyl aryl oxadiazole preparation antiinflammatory, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Category: chlorides-buliding-blocks

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Bala guraiah, M.; Triloknadh, S.; Nagaraju, B.; Rajesh Kumar, T. V.; Vijaya kumari, D.; Venkata Rao, C. published an article in 2019, the title of the article was Synthesis, characterization and biological activity of some novel benzimidazole linked 1,3,4-oxadiazoles.Application of 99-60-5 And the article contains the following content:

Novel benzimidazole derivatives in combination with 1,3,4-oxadiazoles I [R = Ph, pyridin-3-yl, 4-O2NC6H4, etc.] were synthesized from Et 3-((5-chloro-2-nitro phenyl)(phenyl)amino)-3 oxo propanoate via three step synthetic strategy and tested for their antimicrobial activity. The newly synthesized compounds I were characterized by 1HNMR, IR and Mass spectral data. Compounds I [R = Ph, 2,3,4,5-tetrafluorophenyl] showed significant antibacterial activity with tested bacterial pathogens (E.Coli, B.subtilis). The experimental process involved the reaction of 2-Chloro-4-nitrobenzoic acid(cas: 99-60-5).Application of 99-60-5

The Article related to benzimidazole linked oxadiazole preparation antibacterial, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Application of 99-60-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Yashaswini, S. K.; Revanasiddappa, B. C. published an article in 2021, the title of the article was Synthesis and evaluation of antifungal and anti-oxidant activities of novel 1, 2, 4-triazole derivatives.Synthetic Route of 99-60-5 And the article contains the following content:

The key intermediate 4-amino-3-mercapto-1,2,4-triazoles was prepared by reacting with Me paraben carbohydrazide and CS2 to yield potassium dithiocarbazinate salt. The title compounds 4-(6-phenyl-[1,2,4]triazole[3,4-b][1,3,4]thiadiazole-3-yl)-phenol derivatives I [R = CH=CH2, 4-NH2, 3-Cl, etc.] were prepared by reacting 4-amino-3-mercapto-1,2,4-triazole with aromatic acids in the presence of phosphorus oxychloride medium. All the new compounds were evaluated for in-vitro antioxidant and antifungal activities. The new compounds were assigned on the basis of IR, NMR and mass spectral data. The experimental process involved the reaction of 2-Chloro-4-nitrobenzoic acid(cas: 99-60-5).Synthetic Route of 99-60-5

The Article related to aryltriazolethiadiazolyl phenol preparation antifungal antioxidant, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Synthetic Route of 99-60-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Ramzan, Ayesha; Nazeer, Areesha; Irfan, Ahmad; Al-Sehemi, Abdullah G.; Verpoort, Francis; Khatak, Zafar A.; Ahmad, Aftab; Munawar, Munawar A.; Khan, Misbahul A.; Basra, Muhammad Asim Raza published an article in 2019, the title of the article was Synthesis and Antiplatelet Potential Evaluation of 1,3,4-Oxadiazoles Derivatives.Synthetic Route of 99-60-5 And the article contains the following content:

A novel series of 2-(3-methyl-1,6-diphenyl-1H-pyrazolo[3,4-b]pyridin-4-yl)-5-aryl-1,3,4-oxadiazoles I [R = furan-2-yl, pyridin-4-yl, 4-tolyl, etc.] were synthesized from corresponding hydrazones and evaluated their antiplatelet aggregation effect induced by arachidonic acid and collagen. Spectral data and elemental evaluation were used to confirm the structure of the compounds while mol. docking against cyclooxygenase 1 and 2 (COX1 & COX2) and quant. structure-activity relationship (QSAR) were performed in describing their antiplatelet potential. All synthesized compounds I exhibited more than 50% platelet aggregation inhibition against both arachidonic acid and collagen. Antiplatelet activities results showed that I [R = 4-nitrophenyl, furan-2-yl] compounds was highest % inhibition against arachidonic acid. High Egap and ionization potential values showed that the compound I [R = 4-bromophenyl, 4-tolyl, furan-2-yl] were supposed to be more active and good electron donor while I [R = 4-nitrophenyl, 4-fluorophenyl, 4-bromophenyl, 4-tolyl, pyridin-4-yl, 2-chloro-4-nitrophenyl] might be more active due to more electrophilic sites. Interaction with more than one residues in the binding pocket of COX-1 in comparison with aspirin and ligand efficacy (LE) consequences showed that compounds were excellent action potential for COX-1. Computational evaluations were in good agreement with antiplatelet activities of the compounds All compounds might be promising antiplatelet agents especially I [R = 4-nitrophenyl, furan-2-yl] and helpful in the synthesis of new drugs for the treatment of cardiovascular diseases (CVDs). The experimental process involved the reaction of 2-Chloro-4-nitrobenzoic acid(cas: 99-60-5).Synthetic Route of 99-60-5

The Article related to diphenyl pyrazolopyridinyl aryloxadiazole preparation antiplatelet activity mol docking, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Synthetic Route of 99-60-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics