Tag: 0-100

Recommanded Product: Sodium chlorideIn 2019 ,《Rapid sample-saving biophysical characterization and long-term storage stability of liquid interferon alpha2a formulations: Is there a correlation?》 appeared in International Journal of Pharmaceutics (Amsterdam, Netherlands). The author of the article were Svilenov, Hristo; Winter, Gerhard. The article conveys some information:

The knowledge and tools to characterize proteins have comprehensively developed in the last two decades. Some of these tools are used in formulation development to select formulation conditions suitable for long-term storage. However, there is an ongoing debate whether the predictions obtained with these tools are in good agreement with the outcome from real-time long-term stability studies. In this work, we investigate whether some of the state-of-the-art microscale, microvolume and non destructive biophys. techniques can be applied to promptly select formulations that minimise the aggregation of interferon alpha2a during storage. Interferon alpha2a was used as a model protein as it is known to form aggregates at concentrations over an order of magnitude higher than used in the com. product. We apply a systematic formulation approach in which we investigate the effect of pH and ionic strength on protein stability. The predictions from the sample-saving biophys. characterization are validated by long-term stability studies at 4 °C and 25 °C for 12 mo on selected formulations. Interferon alpha2a shows minimal aggregation in 10 mM sodium acetate buffer with pH 4 and low ionic strength. The latter is indicated by the rapid sample-saving biophys. characterization and confirmed by the long-term stability data. In addition to this study using Sodium chloride, there are many other studies that have used Sodium chloride(cas: 7647-14-5Recommanded Product: Sodium chloride) was used in this study.

Sodium chloride(cas: 7647-14-5) has been used for the preparation of tris buffered saline, phosphate buffered saline, MPM-2 (mitotic protein monoclonal 2) cell lysis buffer, immunoprecipitation wash buffer, LB (Luria-Bertani) media and dialysis buffer.Recommanded Product: Sodium chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Reference of Sodium chlorideIn 2021 ,《The effects of sodium chloride on proteins aggregation, conformation and gel properties of pork myofibrillar protein Running Head: Relationship aggregation, conformation and gel properties》 appeared in Journal of Food Science and Technology (New Delhi, India). The author of the article were Kang, Zhuang-Li; Zhang, Xue-hua; Li, Xiang; Song, Zhao-jun; Ma, Han-jun; Lu, Fei; Zhu, Ming-ming; Zhao, Sheng-ming; Wang, Zheng-rong. The article conveys some information:

The objective of this study was to evaluate relationship with aggregation, secondary structures and gel properties of pork myofibrillar protein with different sodium chloride (1%, 2% and 3%). When the sodium chloride increased from 1 to 3%, the active sulfhydryl, surface hydrophobicity, hardness and cooking yield of myofibrillar protein were increased significantly (p < 0.05), the particle size, total sulfhydryl and Zeta potential were decreased significantly (p < 0.05), these meant the aggregations of pork myofibrillar protein were decreased. The changes of proteins aggregation induced the strongest intensity band of Amide I shifted up from 1660 cm-1 to 1661 cm-1, meanwhile, the β-sheet structure content was increased significantly (p < 0.05) with the sodium chloride increased. From the above, the lower proteins aggregation and higher β-sheet structure content could improve the water holding capacity and texture of pork myofibrillar protein gel. After reading the article, we found that the author used Sodium chloride(cas: 7647-14-5Reference of Sodium chloride)

Sodium chloride(cas: 7647-14-5) has been used for the preparation of tris buffered saline, phosphate buffered saline, MPM-2 (mitotic protein monoclonal 2) cell lysis buffer, immunoprecipitation wash buffer, LB (Luria-Bertani) media and dialysis buffer.Reference of Sodium chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The author of 《Salt in freshwaters: causes, effects and prospects – introduction to the theme issue》 were Canedo-Arguelles, Miguel; Kefford, Ben; Schafer, Ralf. And the article was published in Philosophical Transactions of the Royal Society, B: Biological Sciences in 2019. SDS of cas: 7647-14-5 The author mentioned the following in the article:

Humans are globally increasing the salt concentration of freshwaters (i.e. freshwater salinization), leading to significant effects at the population, community and ecosystem level. The present theme issue focuses on priority research questions and delivers results that contribute to shaping the future research agenda on freshwater salinization as well as fostering our capacity to manage salinization. The issue is structured along five topics: (i) the estimation of future salinity and evaluation of the relative contribution of the different drivers; (ii) the physiol. responses of organisms to alterations in ion concentrations with a specific focus on the osmophysiol. of freshwater insects and the responses of different organisms to seawater intrusion; (iii) the impact of salinization on ecosystem functioning, also considering the connections between riparian and stream ecosystems; (iv) the role of context in moderating the response to salinization. The contributions scrutinize the role of addnl. stressors, biotic interactions, the identify of the ions and their ratios, as well as of the biogeog. and evolutionary context; and (v) the public discourse on salinization and recommendations for management and regulation. In this paper we introduce the general background of salinization, outline research gaps and report key findings from the contributions to this theme issue. The experimental part of the paper was very detailed, including the reaction process of Sodium chloride(cas: 7647-14-5SDS of cas: 7647-14-5)

Sodium chloride(cas: 7647-14-5) has been used for the preparation of tris buffered saline, phosphate buffered saline, MPM-2 (mitotic protein monoclonal 2) cell lysis buffer, immunoprecipitation wash buffer, LB (Luria-Bertani) media and dialysis buffer.SDS of cas: 7647-14-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

In 2019,Proceedings of the National Academy of Sciences of the United States of America included an article by Jang, Moon Sun; Toyoshima, Yu; Tomioka, Masahiro; Kunitomo, Hirofumi; Iino, Yuichi. Reference of Sodium chloride. The article was titled 《Multiple sensory neurons mediate starvation-dependent aversive navigation in Caenorhabditis elegans》. The information in the text is summarized as follows:

Animals demonstrate flexible behaviors through associative learning based on their experiences. Deciphering the neural mechanisms for sensing and integrating multiple types of sensory information is critical for understanding such behavioral controls. The soil nematode Caenorhabditis elegans avoids salt concentrations it has previously experienced under starvation conditions. Here, we identify a pair of sensory neurons, the ASG neuron pair, which in cooperation with the ASER salt-sensing neuron generate starvation-dependent salt avoidance. Animals whose sensory input is restricted to only ASER failed to show learned avoidance due to inappropriately directed navigation behaviors. However, their navigation through a salt concentration gradient was improved by allowing sensory inputs to ASG in addition to ASER. Detailed behavioral analyses of these animals revealed that input from ASG neurons is required not only for controlling the frequency of initiating a set of sharp turns (called pirouettes) based on detected ambient salt concentrations but also adjusting the migration direction during pirouettes. Optogenetic activation of ASER by ChR2 induced turning behaviors in a salt concentration-dependent manner where presence of intact ASG was important for the starvation-dependent responses. Calcium imaging of the activity of ASG neurons in freely moving worms revealed that ASG is activated upon turning behavior. Our results indicate that ASG neurons cooperate with the ASER neuron to generate destination-directed reorientation in starvation-associated salt concentration avoidance. After reading the article, we found that the author used Sodium chloride(cas: 7647-14-5Reference of Sodium chloride)

Sodium chloride(cas: 7647-14-5) has been used for the preparation of tris buffered saline, phosphate buffered saline, MPM-2 (mitotic protein monoclonal 2) cell lysis buffer, immunoprecipitation wash buffer, LB (Luria-Bertani) media and dialysis buffer.Reference of Sodium chloride

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The author of 《Evolved tolerance to freshwater salinization in zooplankton: life-history trade-offs, cross-tolerance and reducing cascading effects》 were Hintz, William D.; Jones, Devin K.; Relyea, Rick A.. And the article was published in Philosophical Transactions of the Royal Society, B: Biological Sciences in 2019. Related Products of 7647-14-5 The author mentioned the following in the article:

Recent discoveries have documented evolutionary responses to freshwater salinization. We investigated if evolutionary responses to salinization exhibit life-history trade-offs or if they can mitigate ecol. impacts such as cascading effects through mechanisms of tolerance and cross-tolerance. We conducted an outdoor mesocosm experiment using populations of Daphnia pulex-a ubiquitous algal grazer-that were either naive or had previously experienced selection to become more tolerant to sodium chloride (NaCl). During the initial phase of population growth, we discovered that evolved tolerance comes at the cost of slower population growth in the absence of salt. We found evolved Daphnia populations maintained a tolerance to NaCl approx. 30 generations after the initial discovery. Evolved tolerance to NaCl also conferred cross-tolerance to a high concentration of CaCl2 (3559μS cm-1) and a moderate concentration of MgCl2 (967μS cm-1). A higher concentration of MgCl2 (2188μS cm-1) overwhelmed the cross-tolerance and killed all Daphnia. Tolerance to NaCl did not mitigate NaCl-induced cascades leading to phytoplankton blooms, but cross-tolerance at moderate concentrations of MgCl2 and high concentrations of CaCl2 mitigated such cascading effects caused by these two salts. These discoveries highlight the important interplay between ecol. and evolution in understanding the full impacts of freshwater salinization. After reading the article, we found that the author used Sodium chloride(cas: 7647-14-5Related Products of 7647-14-5)

Sodium chloride(cas: 7647-14-5) has been used for the preparation of tris buffered saline, phosphate buffered saline, MPM-2 (mitotic protein monoclonal 2) cell lysis buffer, immunoprecipitation wash buffer, LB (Luria-Bertani) media and dialysis buffer.Related Products of 7647-14-5

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

The author of 《MOF-positioned polyamide membranes with a fishnet-like structure for elevated nanofiltration performance》 were Zhu, Junyong; Hou, Jingwei; Yuan, Shushan; Zhao, Yan; Li, Yi; Zhang, Ruijun; Tian, Miaomiao; Li, Jian; Wang, Jing; Van der Bruggen, Bart. And the article was published in Journal of Materials Chemistry A: Materials for Energy and Sustainability in 2019. Formula: ClNa The author mentioned the following in the article:

Metal-organic frameworks (MOFs) are increasingly utilized for the design of mol. sieve membranes with unprecedented separation performance, mainly attributed to their nanopore structure and superior polymer affinity. Herein, UiO-66-NH2 crystals were synthesized as functional nanofillers to prepare polyamide (PA) composite membranes. The aqueous solution containing piperazine and evenly dispersed UiO-66-NH2 was transferred onto a membrane surface via vacuum filtration, followed by interfacial polymerization (IP) with trimesoyl chloride (TMC). Covalent bonding between the terminal amine groups of Zr-MOFs and TMC enables the stable immobilization of MOF crystals in the formed PA layer. The positioned MOF nanoaggregates that serve as robust nodes connected by the formed continuous striped film after IP reaction facilitate a rough, fishnet-like surface, which has a larger surface area in comparison to the nodular structure. This unique structure is beneficial for the creation of increased water transport channels, while not compromising the salt rejection. The best performing TFN membranes with a loading mass of 20.5 μg cm-2 exhibited a favorable Na2SO4 rejection of 97.5%, and excellent water permeability (30.8 L m-2 h-1 bar-1). This facile, controlled loading of hydrophilic MOFs via vacuum filtration allows fabrication of crumpled PA membranes with outstanding separation performance. The experimental process involved the reaction of Sodium chloride(cas: 7647-14-5Formula: ClNa)

Sodium chloride(cas: 7647-14-5) has been used for the preparation of tris buffered saline, phosphate buffered saline, MPM-2 (mitotic protein monoclonal 2) cell lysis buffer, immunoprecipitation wash buffer, LB (Luria-Bertani) media and dialysis buffer.Formula: ClNa

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics