Tag: 800-900

In 2022,Fried, Alan D.; Wilson, Breana J.; Galan, Nicholas J.; Brantley, Johnathan N. published an article in Journal of the American Chemical Society. The title of the article was 《Electroediting of Soft Polymer Backbones》.Synthetic Route of C43H72Cl2P2Ru The author mentioned the following in the article:

Synthetic methods that edit soft polymer backbones are critical technologies for tailoring the structures and properties of macromols. Developing strategies that leverage underexplored reaction manifolds are vital for accessing new chem. (and functional) space in soft materials. Here, we report a mild electrochem. approach that enables both degradation and functionalization of synthetic polymers. We found that bulk electrolysis (under either homogeneous or heterogeneous conditions) promoted facile, chemoselective chain scission in a variety of olefin-containing materials. Polymer degradation could also be coupled with functionalization (e.g., azidation) to afford new species that could serve as macromonomers. In the experiment, the researchers used Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9Synthetic Route of C43H72Cl2P2Ru)

Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is a ruthenium-based olefin metathesis catalyst. It is useful for olefin cross metathesis (CM) and ring closing metathesis (RCM) of terminal olefins under a variety of reactions conditions, and so on.Synthetic Route of C43H72Cl2P2Ru

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Ring-closing metathesis of prochiral oxaenediynes to racemic 4-alkenyl-2-alkynyl-3,6-dihydro-2H-pyrans》 was written by Kolarikova, Viola; Rybackova, Marketa; Svoboda, Martin; Kvicala, Jaroslav. Reference of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium And the article was included in Beilstein Journal of Organic Chemistry in 2020. The article conveys some information:

The prochiral 4-(allyloxy)hepta-1,6-diynes, optionally modified in the positions 1 and 7 with an alkyl or ester group, undergo a chemoselective ring-closing enyne metathesis yielding racemic 4-alkenyl-2-alkynyl-3,6-dihydro-2H-pyrans. Among the catalysts tested, Grubbs 1st generation precatalyst in the presence of ethene (Mori conditions) gives superior results compared to the more stable Grubbs or Hoveyda-Grubbs 2nd generation precatalysts. This was probably caused by a suppression of the subsequent sidereactions of the enyne metathesis product with ethene. On the other hand, the 2nd generation precatalysts gives better yields in the absence of ethene. The metathesis products, containing both a triple bond and a conjugated system, can be successfully orthogonally modified. For example, the metathesis product of 5-(allyloxy)nona-2,7-diyne reacted chemo- and stereoselectively in a Diels-Alder reaction with N-phenylmaleimide affording the tricyclic products as a mixture of two separable diastereoisomers, the configuration of which was estimated by DFT computations. The reported enediyne metathesis paves the way to the enantioselective enyne metathesis yielding chiral building blocks for compounds with potential biol. activity, e.g., norsalvinorin or cacospongionolide B. In the experiment, the researchers used many compounds, for example, Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9Reference of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium)

Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is the first metathesis catalyst to be widely used in organic synthesis. It is useful for acyclic diene metathesis polymerization (ADMET), Ring-Opening Metathesis Polymerization (ROMP) of strained cyclic olefins, ring opening metathesis (ROM), and so on.Reference of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Synthesis of high-molecular weight poly(1,1-dimethyl-1-silapentene) by olefin metathesis polymerization in the presence of Grubbs catalysts》 was written by Morontsev, Alexander; Gringolts, Maria; Lakhtin, Valentin; Finkelshtein, Eugene. Application of 172222-30-9 And the article was included in Journal of Organometallic Chemistry in 2020. The article conveys some information:

Heterochain polycarbosilanes are well-known materials possessed important properties. Some of their applications, such as gas separation membranes, require polymers with high mol. weight that provide good film-forming and mech. properties. In this research, the synthesis of poly(1,1-dimethyl-1-silapentene) via the ring-opening metathesis polymerization (ROMP) of 1,1-dimethyl-1-silacyclopentene and the acyclic dienes metathesis (ADMET) of diallyl dimethylsilane mediated by Ru-carbene Grubbs complexes 1st – 3rd generations as well as Hoveyda-Grubbs 2nd generation catalyst were studied for the first time. High mol. weight poly(1,1-dimethyl-1-silapentene) was synthesized by ROMP of 1,1-dimethyl-1-silacyclopentene. Varying the type and loading catalyst, temperature and monomer concentration, we obtained poly(1,1-dimethyl-1-silapentene) with Mw = 100-143 kDa, which is significantly higher (5-7 times) than that reached previously by olefin metathesis polymerization The activities of 1,1-dimethyl-1-silacyclopentene and cyclopentene in ROMP were compared using 1H NMR monitoring the conversion of their double bonds. The ADMET polymerization of diallyl dimethylsilane led to oligomers with the average polymerization degree not exceeded 4.4. In the part of experimental materials, we found many familiar compounds, such as Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9Application of 172222-30-9)

Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is the first metathesis catalyst to be widely used in organic synthesis. It is useful for acyclic diene metathesis polymerization (ADMET), Ring-Opening Metathesis Polymerization (ROMP) of strained cyclic olefins, ring opening metathesis (ROM), and so on.Application of 172222-30-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Fabricating Organic Nanotubes through Selective Disassembly of Two-Dimensional Covalent Organic Frameworks》 was published in Journal of the American Chemical Society in 2020. These research results belong to Liang, Rong-Ran; A, Ru-Han; Xu, Shun-Qi; Qi, Qiao-Yan; Zhao, Xin. Recommanded Product: 172222-30-9 The article mentions the following:

Covalent organic frameworks (COFs) are an emerging class of crystalline porous organic polymers with potential for innovative applications. Here we report the use of COFs as precursors for the fabrication of well-defined tubular nanomaterials. A proof-of-concept study is presented for the controllable fabrication of organic nanotubes through selective disassembly of two-dimensional heteropore COFs. Two dual-pore COFs are constructed based on orthogonal reactions. Each COF possesses two different kinds of pores, which are formed by linking all-hydrazone-bonded nanopores with boroxines. Selectively hydrolyzing boroxine rings in the COFs while keeping hydrazone linkages untouched gives rise to organic nanotubes with diameters and shapes corresponding to the nanochannels of the COFs. The experimental part of the paper was very detailed, including the reaction process of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9Recommanded Product: 172222-30-9)

Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is a ruthenium-based olefin metathesis catalyst. It is useful for olefin cross metathesis (CM) and ring closing metathesis (RCM) of terminal olefins under a variety of reactions conditions, and so on.Recommanded Product: 172222-30-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Product Details of 172222-30-9In 2020 ,《One-Step Ring Opening Metathesis Block-Like Copolymers and their Compositional Analysis by a Novel Retardation Technique》 was published in Angewandte Chemie, International Edition. The article was written by Yasir, Mohammad; Liu, Peng; Markwart, Jens C.; Suraeva, Oksana; Wurm, Frederik R.; Smart, Jansie; Lattuada, Marco; Kilbinger, Andreas F. M.. The article contains the following contents:

Using a one-step synthetic route for block copolymers avoids the repeated addition of monomers to the polymerization mixture, which can easily lead to contamination and, therefore, to the unwanted termination of chain growth. For this purpose, monomers (M1-M5) with different steric hindrances and different propagation rates are explored. Copolymerization of M1 (propagating rapidly) with M2 (propagating slowly), M1 with M3 (propagating extremely slowly) and M4 (propagating rapidly) with M5 (propagating slowly) yielded diblock-like copolymers using Grubbs’ first (G1) or third generation catalyst (G3). The monomer consumption was followed by 1H NMR spectroscopy, which revealed vastly different reactivity ratios for M1 and M2. In the case of M1 and M3, we observed the highest difference in reactivity ratios (r1=324 and r2=0.003) ever reported for a copolymerization method. A triblock-like copolymer was also synthesized using G3 by first allowing the consumption of the mixture of M1 and M2 and then adding M1 again. In addition, in order to measure the fast reaction rates of the G3 catalyst with M1, we report a novel retardation technique based on an unusual reversible G3 Fischer-carbene to G3 benzylidene/alkylidene transformation. In the part of experimental materials, we found many familiar compounds, such as Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9Product Details of 172222-30-9)

Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is the first metathesis catalyst to be widely used in organic synthesis. It is useful for acyclic diene metathesis polymerization (ADMET), Ring-Opening Metathesis Polymerization (ROMP) of strained cyclic olefins, ring opening metathesis (ROM), and so on.Product Details of 172222-30-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Synthesis and Characterization of Rigid-Rod Polymers with Silsesquioxanes in the Main Chain》 was written by Guan, Jun; Zhang, Zijing; Laine, Richard M.. Application of 172222-30-9This research focused onvinyl silsesquioxane main chain metathesis photopolymerization. The article conveys some information:

Two double-decker silsesquioxane-based rigid-rod polymers/oligomers were synthesized using olefin self-metathesis and photolysis. In both synthetic routes, double-decker (DD) silsesquioxanes (SQs) with di- and tetra-vinyl functionalities were studied, and all products were characterized in detail by NMR (NMR), MALDI-TOF, GPC, TGA, and Fourier transform IR (FTIR) spectroscopy. The catalytic self-metathesis of di-vinyl-functionalized DD SQs results in rigid-rod oligomers with a simple ethene bridge linking SQ cages with a decomposition temperature Td5% of ~530° C in air. Due to steric hindrance, only one ethene bridge forms between tetra-vinyl-functionalized DD SQs using either Grubb’s 1st or 2nd generation catalysts, with other vinyl groups remaining unreacted, as indicated by MALDI-TOF. As an alternative approach, photolysis of di-vinylDD SQs in the UVA and UVB regions leads to linear polymers with cyclobutane linkers between SQ cages and a Td5% of ~530° C. In both configurations, the degrees of freedom are limited solely to rotation around the single bonds joining the ethene or cyclobutane groups to the DD SQs along the chain axis, leading to rigid-rod polymers. Rigid-rod polymers remain both highly thermally stable and soluble in common solvents such as dichloromethane and THF, which points to new opportunities in easily processable rigid-rod polymers. In contrast, photolysis of tetra-vinylDD SQs leads to insoluble and unmeltable products, implying a high degree of crosslinking. The results came from multiple reactions, including the reaction of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9Application of 172222-30-9)

Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is the first metathesis catalyst to be widely used in organic synthesis. It is useful for acyclic diene metathesis polymerization (ADMET), Ring-Opening Metathesis Polymerization (ROMP) of strained cyclic olefins, ring opening metathesis (ROM), and so on.Application of 172222-30-9

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

In 2022,Nagyhazi, Marton; Lukacs, Adam; Turczel, Gabor; Hancsok, Jeno; Valyon, Jozsef; Benyei, Attila; Keki, Sandor; Tuba, Robert published an article in Angewandte Chemie, International Edition. The title of the article was 《Catalytic Decomposition of Long-Chain Olefins to Propylene via Isomerization-Metathesis Using Latent Bicyclic (Alkyl)(Amino)Carbene-Ruthenium Olefin Metathesis Catalysts》.Reference of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium The author mentioned the following in the article:

One of the most exciting scientific challenges today is the catalytic degradation of non-biodegradable polymers into value-added chem. feedstocks. The mild pyrolysis of polyolefins, including high-d. polyethylene (HDPE), results in pyrolysis oils containing long-chain olefins as major products. In this paper, novel bicyclic (alkyl)(amino)carbene ruthenium (BICAAC-Ru) temperature-activated latent olefin metathesis catalysts, which can be used for catalytic decomposition of long-chain olefins to propylene are reported. These thermally stable catalysts show significantly higher selectivity to propylene at a reaction temperature of 75°C compared to second generation Hoveyda-Grubbs or CAAC-Ru catalysts under ethenolysis conditions. The conversion of long-chain olefins (e.g., 1-octadecene or Me oleate) to propylene via isomerization-metathesis is performed by using a (RuHCl)(CO)(PPh3)3 isomerization co-catalyst. The reactions can be carried out at a BICAAC-Ru catalyst loading as low as 1 ppm at elevated reaction temperature (75°C). The observed turnover number and turnover frequency are as high as 55 000 and 10 000 molpropylene molcatalyst-1 h-1, resp. The experimental process involved the reaction of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9Reference of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium)

Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is the first metathesis catalyst to be widely used in organic synthesis. It is useful for acyclic diene metathesis polymerization (ADMET), Ring-Opening Metathesis Polymerization (ROMP) of strained cyclic olefins, ring opening metathesis (ROM), and so on.Reference of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Safety of Benzylidenebis(tricyclohexylphosphine)dichlororutheniumIn 2021 ,《Polymer Skeletal Editing via Anionic Brook Rearrangements》 appeared in Journal of the American Chemical Society. The author of the article were Ratushnyy, Maxim; Zhukhovitskiy, Aleksandr V.. The article conveys some information:

This report communicates the first example of polymer backbone metamorphosis affected by anionic 1,2-Brook rearrangement of acyl silane moieties. Introduction of the acyl silane functionality into a polymer backbone was achieved via acyclic diene metathesis copolymerization (ADMET) of diene 1 and two dienes. We demonstrate that, using organolithium species and cyanide as nucleophiles, the backbones of resulting copolymers can be triggered to undergo highly efficient 1,2-Brook rearrangement, which transforms the poly(acyl silane)s into poly(silyl ether)s. Furthermore, the carbanion intermediate of the 1,2-Brook rearrangement can be intercepted by ketone electrophiles to give rise to polymers with quaternary stereogenic centers in the backbone and pendant functionality. Such structural editing of polymer backbones enables a new retrosynthetic paradigm for silicon-containing polymers that could not be accessed by traditional means. In the experimental materials used by the author, we found Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9Safety of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium)

Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is the first metathesis catalyst to be widely used in organic synthesis. It is useful for acyclic diene metathesis polymerization (ADMET), Ring-Opening Metathesis Polymerization (ROMP) of strained cyclic olefins, ring opening metathesis (ROM), and so on.Safety of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Reference of Benzylidenebis(tricyclohexylphosphine)dichlororutheniumIn 2020 ,《Cell Engineering with Functional Poly(oxanorbornene) Block Copolymers》 appeared in Angewandte Chemie, International Edition. The author of the article were Church, Derek C.; Pokorski, Jonathan K.. The article conveys some information:

Cell-based therapies are gaining prominence in treating a wide variety of diseases and using synthetic polymers to manipulate these cells provides an opportunity to impart function that could not be achieved using solely genetic means. Herein, we describe the utility of functional block copolymers synthesized by ring-opening metathesis polymerization (ROMP) that can insert directly into the cell membrane via the incorporation of long alkyl chains into a short polymer block leading to non-covalent, hydrophobic interactions with the lipid bilayer. Furthermore, we demonstrate that these polymers can be imbued with advanced functionalities. A photosensitizer was incorporated into these polymers to enable spatially controlled cell death by the localized generation of 1O2 at the cell surface in response to red-light irradiation In a broader context, we believe our polymer insertion strategy could be used as a general methodol. to impart functionality onto cell-surfaces.Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9Reference of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium) was used in this study.

Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is the first metathesis catalyst to be widely used in organic synthesis. It is useful for acyclic diene metathesis polymerization (ADMET), Ring-Opening Metathesis Polymerization (ROMP) of strained cyclic olefins, ring opening metathesis (ROM), and so on.Reference of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

《Metathesis of norbornene-derivatives bearing trimethylsilyl groups using Ru-alkylidene catalysts: An experimental and computational study》 was written by Zarate-Saldana, Daniel; Landeros-Rivera, Bruno; Cruz-Morales, Jorge A.; Gutierrez, Selena. Safety of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium And the article was included in Journal of Organometallic Chemistry in 2020. The article conveys some information:

The monomer synthesis and ring-opening metathesis polymerization (ROMP) of cis-5-norbornene-exo-2,3-dicarboxylic anhydride (1a) and 7-syn-trimethylsilyl-cis-5-norbornene-exo-2,3-dicarboxylic anhydride (1b) mediated by ruthenium-alkylidene catalysts (I, II and III) were exptl. carried out. Metathesis reaction pathways of 1a and 1b monomers using II have been studied at PBE-D3(BJ)/def2-TZVP level of theory, employing the SMD model for simulation of 1,2-dichloroethane solvent. The calculations unravel that reactivity difference between 1a and 1b towards ruthenium alkylidene complex II is due to the fact that the intermediate π-complex formation was found in the 1a reaction pathway but was absent in the 1b one. Moreover, there are marked differences in the formation processes of the metallacyclobutane intermediaries 5a and 5b, the first is an exergonic process (-8.3 kcal/mol) and the last one is an endergonic process (2 kcal/mol), in addition to the high activation energy of the monomer 1b (15.8 kcal/mol) compared with 1a (5.5 kcal/mol). Such differences are attributed to the high steric impediment imposed by -Si(CH3)3 over the double bond (syn conformation). Using quantum theory of atoms in mols. (QTAIM) it was possible to analyze successfully the mechanistic pathway of metathesis reaction for both monomers, complementing the results obtained by DFT energetic anal. After reading the article, we found that the author used Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9Safety of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium)

Benzylidenebis(tricyclohexylphosphine)dichlororuthenium(cas: 172222-30-9) is the first metathesis catalyst to be widely used in organic synthesis. It is useful for acyclic diene metathesis polymerization (ADMET), Ring-Opening Metathesis Polymerization (ROMP) of strained cyclic olefins, ring opening metathesis (ROM), and so on.Safety of Benzylidenebis(tricyclohexylphosphine)dichlororuthenium

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics