Tag: M.W=250-300

Sanli, Nazmiye Ozlem published the artcileEvaluation of biocidal efficacy of Chloramine T trihydrate on planktonic and sessile bacteria in a model cooling tower water system, Name: Sodium chloro(tosyl)amide trihydrate, the publication is Water Science and Technology (2019), 79(3), 526-536, database is CAplus and MEDLINE.

In the current study, model cooling tower system was exptl. seeded with Legionella pneumophila and real industrial cooling tower (CT) water has been run at the closest to full-scale system operating conditions. The water/biofilm samples were taken from the model system monthly, and the effectiveness of the different concentrations of Chloramine T trihydrate biocide was evaluated in terms of its ability to control both planktonic/sessile microbial populations. Although Chloramine T is a recommended com. formulation for disinfecting CTs, there is a lack of published data on the efficacy of this compound against both planktonic and sessile populations in the cooling tower. Biocide response in both sessile/planktonic bacteria counts varied according to months. Tested biocide concentrations provided the clean tower conditions by reducing the concentration of heterotrophic plate count (HPC) below <104 cfu mL-1, L. pneumophila <10 cfu mL-1 and of ATP (ATP) values <300 relative light units (RLU), after 1, 3 and 24 h of exposure, during a 6-mo period. There were no statistically significant differences in efficacy between concentrations in terms of reduction in the number of bacteria, decrease in ATP value and viability. The results revealed that Chloramine T can effectively control biofouling in cooling systems according to the limit values of the successful control program.

Water Science and Technology published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Name: Sodium chloro(tosyl)amide trihydrate.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Sanli, Nazmiye Ozlem published the artcileEffects of material type on biofilm response to an oxidising biocide in a laboratory-scale cooling tower system: Effect of material type in response to biocide, Name: Sodium chloro(tosyl)amide trihydrate, the publication is Johnson Matthey Technology Review (2021), 65(2), 161-169, database is CAplus.

Biofilms in industrial cooling tower systems are an important problem. The importance of the surface material in the response to an oxidising biocide (chloramine T trihydrate) was substantiated in our study. Polyvinyl chloride (PVC) cooling tower fill material, stainless steel cooling tower construction material and glass surfaces were compared by evaluating the bacterial loads on materials before and after biocidal treatment. The greatest logarithmic decrease in bacterial load was recorded as >3 log for glass after the first two months and for PVC after the second month. Actively respiring bacterial counts and ATP (ATP) measurements showed that there was no significant difference in the sensitivity of biofilmassocd. cells to the biocide on the different surfaces. In addition, the effect of the biocidal treatment decreased with increasing biofilm age, regardless of the material.

Johnson Matthey Technology Review published new progress about 7080-50-4. 7080-50-4 belongs to chlorides-buliding-blocks, auxiliary class Halogenation Reagent,Inhibitor, name is Sodium chloro(tosyl)amide trihydrate, and the molecular formula is C7H13ClNNaO5S, Name: Sodium chloro(tosyl)amide trihydrate.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Venkat Rao, S. published the artcileA Cu (I) catalyzed large scale synthesis of an antipsychotic drug substance Clozapine with new precursor 2-chloro benzoic acid, Category: chlorides-buliding-blocks, the publication is Arabian Journal of Chemistry (2020), 13(7), 6040-6043, database is CAplus.

Development of an economic and com. manufacturing process for an anti-psychotic drug substance clozapine I with an alternative key starting material (2-chloro benzoic acid) in the place of literature reported key starting material Anthranilic acid. To avoid narcotic key starting materials usage in drug substances the author invented a com. available raw material 2-chlorobenzoic acid, which reacts with another key starting material 4-chloro-1,2-diamino benzene. This reaction proceeded through Ullman reaction to produce multi scale level Clozapine which quality meets the ICH requirements.

Arabian Journal of Chemistry published new progress about 60091-87-4. 60091-87-4 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Nitro Compound,Carboxylic acid,Amine,Benzene, name is 2-((4-Chloro-2-nitrophenyl)amino)benzoic acid, and the molecular formula is C10H12BNO3S, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Ilhan, Suleyman published the artcileEssential Oils from Vitex agnus castus L. Leaves Induces Caspase-Dependent Apoptosis of Human Multidrug-Resistant Lung Carcinoma Cells through Intrinsic and Extrinsic Pathways, Product Details of C10H9ClF3NO2, the publication is Nutrition and Cancer (2021), 73(4), 694-702, database is CAplus and MEDLINE.

Essential oil (EO) fractions of plants are complex mixtures of volatile compounds with broad-spectrum biol. properties. In the current study, the EO content of Vitex agnus castus L. (VAC) leaves growing in the Aegean region of Turkey was extracted and identified. Then, VAC EOs were investigated for their potential antioxidant, cytotoxic and apoptotic effects in human H69AR multi-drug resistant cancer cells. EOs were isolated by hydrodistillation and chem. composition was determined by GC-MS. Cell viability was assessed via MTT and trypan blue assays. Antioxidant activity was evaluated by measuring the total antioxidant activity and free radical scavenging activity. Apoptosis was evaluated via DNA fragmentation and caspase 3/7 activity assays. Changes in the levels of apoptotic genes were determined by RT-qPCR. The results indicated strong antioxidant activity and cytotoxic effect on H69AR cancer cells but not on HEK-293 human normal cells indicating the tumor-specific effect. VAC EOs induced caspase 3/7 activation and apoptosis through triggering both extrinsic- and intrinsic-pathways by modulating Bcl-2, Bcl-XL, Bax, Bad, FADD, Caspase-8, Caspase-9, TRAIL R1/DR4 and TRAIL R2/DR5. This study revealed that VAC EOs may be a promising candidate in the development of novel therapeutic agents for multi-drug resistant lung cancer treatment.

Nutrition and Cancer published new progress about 18585-06-3. 18585-06-3 belongs to chlorides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Chloride,Amine,Benzene,Amide, name is Ethyl (4-chloro-3-(trifluoromethyl)phenyl)carbamate, and the molecular formula is C10H9ClF3NO2, Product Details of C10H9ClF3NO2.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Isbell, A. F. published the artcileSynthesis of organophosphorus compounds, Formula: C5H10Cl3O3P, the publication is United States Department of Commerce, Office of Technical Services, AD [ASTIA Document] (1961), 9 pp., database is CAplus.

Monoalkylphosphonates of the type RP(O)(OR’)₂(R = R’ = Me, Et, or Bu; R = Ph, R’ = Et; R = PhCH₂, R’ = Bu) were treated with Na metal, using either PhCH₃ or excess ester as solvent. In all cases, the gas R’H was given off, yields being 0.3-0.5 moles gas/mole ester in PhCH₃ and 0.1 or less in excess ester. In addition, white solids were formed; they were insoluble in PhCH₃ but soluble in excess ester. Viscosity and non-crystalline character increased with increasing mol. weight of R. These solids were believed to consist in part of RP(O)(OR’)ONa. Other compounds studied were (MeO)₃P; (EtO)₃P; (BuO)₃PO; triethyl α,α-dimethylphosphonoacetate; triethyl phosphonoformate; BuPhP(O)OBu, and Et₂P(O)OEt. Attempts were also made to synthesize fluoroalkylphosphonic esters. F₃CCl or F₃Cl with (BuO)₂P(O)Na or (EtO)₃P gave no reaction. (EtO)₃P(O)CCl₃ heated with KF.2H₂O gave 83% CHCl₃ and a salt-like product. RP(O)(OEt)₂ (R = ClCH₂ or Cl₂CH) heated with anhydrous KF gave no reaction, but Cl₃CP(O)(OEt)₂ reacted with KF or NaF to give FP(O)(OEt)₂, (b₄₇ 88.5-89.5°); n²⁷_D 1.3710; d₂₇ 1.1399.

United States Department of Commerce, Office of Technical Services, AD [ASTIA Document] published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, Formula: C5H10Cl3O3P.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Jones, F. William published the artcileFiber-reactive insecticides for wool: organophosphorus esters of nitrogen heterocycles, Formula: C3H3Br2ClO, the publication is Journal of Agricultural and Food Chemistry (1983), 31(2), 190-4, database is CAplus.

O,O-Di-Et phosphorothionate esters and O-Et S-Pr phosphorothiolothionate esters of some pyridazine and 1,2,4-triazole compounds containing a 2-bromoacryloyl ester substituent were synthesized and screened for insecticidal activity against the wool-digesting insects Tineola bisselliella and Anthrenus flavipes. O,O-Diethyl O-[1-(2-hydroxyethyl)-5-methylthio-3-(1,2,4-triazolyl)] phosphorothiolothionate (I) was most active. These compounds were found to be hydrolytically unstable when applied to wool from a boiling acidic dye bath. The extent of this hydrolysis has been determined by the development of a method for estimating organophosphorus esters that are covalently bound to the wool.

Journal of Agricultural and Food Chemistry published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Formula: C3H3Br2ClO.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Mao, Faming published the artcileSynthesis of reactive scarlet 3G, Category: chlorides-buliding-blocks, the publication is Ranliao Yu Ranse (2010), 47(1), 19-20, database is CAplus.

Reactive scarlet 3G was prepared from sodium 2,4-diaminobenzenesulfonate, 2,3-dibromopropanoyl chloride and γ acid by acylation, diazotization, coupling and salting-out. The two steps of acylation were studied emphatically. The complete reaction conditions were obtained by experiments: the temperature of acylation was 0-15°C, pH was controlled between 5-7.5; the molar ratio of 2, 3-dibromopropanoyl chloride and sodium 2,4-diaminobenzenesulfonate was 1.05: 1,2,3-dibromopropanoyl chloride and γ acid molar ratio was 1.05: 1. The yield of acylation was above 90%.

Ranliao Yu Ranse published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Fawzy, Ahmed published the artcileRemoval of toxic tellurium (IV) compounds via bioreduction using flucloxacillin in aqueous acidic medium: A kinetic and mechanistic approach, Recommanded Product: 3-(2-Chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxylic acid, the publication is Journal of Molecular Liquids (2019), 111436pp., database is CAplus.

This paper describes a novel method for the removal of potassium tellurite (Te^IV), a toxic tellurium (IV) compound, via its bioreduction using the drug flucloxacillin (Flx) in an aqueous sulfuric acid solution The kinetics of the bioreduction process were monitored using UV-Vis absorption spectra at an ionic strength of 2.0 mol dm^-3 and 298 K. The reaction between Te^IV and Flx was set at a 1:1 stoichiometry. The reduction reaction followed first-order kinetics for [Flx] and fractional-first-order kinetics for [Te^IV] and [H⁺]. The effects of ionic strength and relative permittivity of the reaction medium were also explored. Supplementation with divalent transition metal ions enhanced the reduction rate. The reaction products were identified, in order of their stoichiometric results, spot tests and FT-IR spectra as 3-(2-chloro-6-fluorophenyl)-5-methylisoxazol-4-carbocylic acid, 5,5-dimethyl-thiazolidine-2,4-dicarboxlic acid, ammonium ion, carbon dioxide and elemental tellurium (Te⁰). The reaction rate dependence on temperature was studied, and the activation and thermodn. parameters were assessed and discussed. The derived rate-law expression was found to be in excellent accordance with the acquired investigational outcomes. A conceivable reaction mechanism has been provided, which includes a reaction between the protonated flucloxacillin (Flx⁺) and tellurous acid (H₂TeO₃) as the essential reactive species, resulting in the construction of an intermediate complex. Such complex decays in the rate-determining step to yield the final reaction products.

Journal of Molecular Liquids published new progress about 3919-74-2. 3919-74-2 belongs to chlorides-buliding-blocks, auxiliary class Isoxazole,Fluoride,Chloride,Carboxylic acid,Benzene, name is 3-(2-Chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxylic acid, and the molecular formula is C11H7ClFNO3, Recommanded Product: 3-(2-Chloro-6-fluorophenyl)-5-methylisoxazole-4-carboxylic acid.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Frank, Arlen W. published the artcileStability of the carbon-phosphorus bond in trichloromethyl- phosphonate esters. Ether formation in reactions with alcohols and phenols, COA of Formula: C5H10Cl3O3P, the publication is Journal of Organic Chemistry (1964), 29(12), 3706-7, database is CAplus.

Prolonged refluxing of a solution of Cl₃CP(O)(OEt)₂ (I) in alc. gave Et₂O and Cl₃CP(O)(OEt)OH. Thus, the ester behaved as an alkylating agent as in the reaction with amines. The reaction was remarkably mild. No alkylation was observed when di-Et ethylphosphonate or di-Et acetylphosphonate were refluxed with alc. under the same conditions. Alkylation of PhOH by I gave 85% phenetole in 4.5 hrs. at 150°.

Journal of Organic Chemistry published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, COA of Formula: C5H10Cl3O3P.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Gramstad, Thor published the artcileStudies of hydrogen bonding. II. Intermolecular hydrogen bond association between organophosphorus compounds and methanol, α-naphthol, and pentachlorophenol, respectively, Recommanded Product: Diethyltrichloromethylphosphonate, the publication is Acta Chemica Scandinavica (1961), 1337-46, database is CAplus.

cf. ibid. 14, 1485(1960). -The K_association ΔH, ΔF, and ΔS values of the equilibrium reaction between organophosphorus compounds and MeOH, α-naphthol (I), and C₆Cl₅OH (II) were determined by infrared measurements. Data were given for the dimeric hydrogen-bond association between 16 organophosphorus compounds and MeOH, I, and II in CCl₄. A comparison of thermodynamic data of H bonds in CS₂ and CCl₄ was made for the compounds PhOH.Ph₃PO and C₆Cl₅OH.Ph₃PO. The following observations were made: (1) the absorption bands due to H-bonding are for each system lowered in frequency, broadened in contour, and enhanced in integrated intensity as the base strength of the proton acceptor increases; (2) the ease with which the H donors studied form H bonds in CCl₄ with the organophosphorus compounds used is, in order of decreasing association constant, I > phenol > II > MeOH; (3) the sequence of the variation ΔH, ΔS with Δv for each system is, in order of decreasing slope, MeOH > phenol > I > II. For the system organophosphorus compounds-MeOH interaction on H bonding is predominantly due to the solvation effect around the H bonded complex; with I both the solvation and the solvent-proton donor effects come into play and with II the solvent-proton donor effect predominates.

Acta Chemica Scandinavica published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, Recommanded Product: Diethyltrichloromethylphosphonate.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics