Tag: M.W=250-300

Gramstad, Thor published the artcileHydrogen bonding. VII. Hydrogen-bond association of phenol and pentachlorophenol with carbonyl compounds and ethers, SDS of cas: 866-23-9, the publication is Spectrochimica Acta (1963), 497-508, database is CAplus.

cf. Acta Chem. Scand. 16, 2368(1962); CA 58, 1333b. The thermodn. data for the 1:1 association of PhOH with 8 esters, 3 acid fluorides, 16 ketones, 14 aldehydes, and 15 ethers in CCl₄ solution were determined The frequency shifts, δv_OH, of the O-H band of PhOH which accompanies the formation of the H bond with various types of proton acceptors (N,N-disubstituted amides, esters, ketones, aldehydes, ethers, and organo-P compounds) are proportional to the corresponding enthalpies of association This relation is not applicable to other proton donors studied. The entropy of association (-ΔS) for the various systems is, in relation to δv_OH, in order of increasing values as follows: organo-P compounds-PhOH <N,N-disubstituted amides-PhOH < esters-PhOH < ketones-PhOH < aldehydes-PhOH < ethers-PhOH < tertiary amines and pyridines-PhOH. The influence of inductive and mesomeric effects on the H-bond association is discussed.

Spectrochimica Acta published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, SDS of cas: 866-23-9.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Gramstad, Thor published the artcileHydrogen bonding. XII. Correlation of the complexing ability of organophosphorus compounds with the Taft σ^* constant, Safety of Diethyltrichloromethylphosphonate, the publication is Spectrochimica Acta (1964), 20(4), 729-31, database is CAplus.

cf. CA 56, 15544b; 58, 1333a; 59, 13792b. The relation of the Taft substituent constant (Σσ^*) is linear with respect to log K^20°_association and the shift of the OH stretching vibration fundamental (Δv_OH) for 22 organophosphorus compounds in mixed solutions with phenol, ethanol, and α-naphthol in CCl₄. Σσ^* is also linear with respect to log K^20°_association for the organophosphorus compounds with iodine in CCl₄ solution, and with the wavelength shift of the visible absorption band of iodine from near 518 mμ. The relation between Σσ^* and P:O stretching frequencies in cm.^-1 (v_PO) is not linear for these organophosphorus compounds in CCl₄ solution, contrary to previous reports (Griffin, CA 55, 1415h). However, some of G.’s determinations of v_PO were on pure films, and these compounds are associated in the pure state.

Spectrochimica Acta published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, Safety of Diethyltrichloromethylphosphonate.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Gramstad, Thor published the artcileStudies of hydrogen bonding. Part XXXIII. Dipole moments of phosphoryl compounds and their hydrogen-bonded complexes with phenol, Application In Synthesis of 866-23-9, the publication is Acta Chemica Scandinavica (1992), 46(11), 1087-91, database is CAplus.

The dipole moments of 33 phosphoryl compounds and of their hydrogen-bonded complexes with phenol have been determined in CCl₄ at 20°. In general there is no correlation between the dipole moments and the O-H stretching frequency shift accompanying the complexation of phenol with the phosphoryl compounds A smooth correlation is observed, however, for some series of closely related phosphoryl compounds The influence of the various substituents on the dipole moment is discussed. The vectorially calculated dipole moments of the complexes were smaller than the corresponding dipole moments obtained exptl. The vectorial difference, Δμ, is greatest for phosphoryl compounds containing the N-P:O and C₆H₅-P:O groups.

Acta Chemica Scandinavica published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, Application In Synthesis of 866-23-9.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Griffin, C. E. published the artcilePhosphoryl stretching frequency correlation for phosphonic acid derivatives, Computed Properties of 866-23-9, the publication is Chemistry & Industry (London, United Kingdom) (1960), 1058-9, database is CAplus.

A plot of Σ σ* (Taft substituent constants) vs. γ_PO (as films in CS₂ or CCl₄) for 19 phosphonates [RP(O)XY] (I) gave a linear relationship; a least squares treatment of the data gave γ_PO = 16.80 Σσ* + 1198. The following I were studied (X = Y = OEt) (R given): Me, Et, Pr, Bu, n-C₆H₁₃, CH₂:CH, CH₂:CHCH₂, PhCH₂, Ph, ClCH₂, Cl₂CH, CCl₃ (II), BrCH₂, HOCH₂, AcCH₂. Also I (R, X, and Y given): Me, OMe, OMe; Me, OEt, NMe₂; Me, NMe₂, NMe₂ (III); Ph, H, OEt. The average deviation between calculated and observed frequencies was ±4 cm.^-1; the only significant deviation occurred with II and III, and may have arisen through disturbance of the normal inductive effects of the substituents by field effects. Major deviations from the linear relationship also occurred with frequency values obtained in the presence of H-bonding solvents. The following σ* values were tentatively assigned: (CH₂)₂CO₂Et, 0.39; (CH₂)₃CO₂Et, 0.39; NEt₂, 0.68.

Chemistry & Industry (London, United Kingdom) published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, Computed Properties of 866-23-9.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Griffin, C. E. published the artcileReaction of trichloromethyl radicals with triethyl phosphite, Category: chlorides-buliding-blocks, the publication is Chemistry & Industry (London, United Kingdom) (1958), 415, database is CAplus.

CCl₄ and (EtO)₃P at 80° give 80-5% Cl₃CP(O)(OEt)₂ (I). The reaction is inhibited by hydroquinone but traces of Bz₂O₂ give a 4-fold increase in reaction rate (89% yield at 80°). Irradiation of the reaction mixture at room temperature with a Hanovia ultraviolet lamp gives 80% I; under similar conditions BrCCl₃ and (EtO)₃P give 88% I. No reaction is observed in the dark at room temperature (30 days). These results confirm the chain process proposed by Kamai and Kharrasova (C.A. 52, 3666a). I b₁₇ 137-8°, n²¹_D 1.4612; partial hydrolysis with PhNH₂ in PhMe at 110° gave the anilinium salt of monoethyl trichloromethanephosphonate, m. 181.6-2.2° (MeOH-PhMe).

Chemistry & Industry (London, United Kingdom) published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Holy, A. published the artcilePhosphorylation of nucleosides with trichloromethylphosphonic acid derivatives, HPLC of Formula: 866-23-9, the publication is Tetrahedron Letters (1972), 157-8, database is CAplus.

Ribonucleosides were phosphorylated selectively, to give the 2′-phosphate derivative, with Et trichloromethylphosphonate (I) when the ribonucleoside contained the cis-2′,3′-diol group. Treatment of uridine (over-night) with I in HCONMe2 containing Et3N gave 67% of the corresponding uridine nucleotide. Similarly prepared were the nucleotides of cytidine, adenosine, and 6-azauridine in 23, 45, and 3% yield, resp. Thymidine and 2′,3′-O-isopropylideneuridine did not give the nucleotides as they could not form a cyclic intermediate. -(α-L-Lyxofuranosyl)adenine, in which two cyclic intermediates were conformationally allowed, gave 95% of a nucleotide mixture containing 2- and 3-isomeric phosphates and the 3,5-cyclic phosphate in 23, 37, and 35% yield, resp.

Tetrahedron Letters published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, HPLC of Formula: 866-23-9.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Kharrasova, F. M. published the artcileReaction of phosphorus(III) acid esters with carbon tetrachloride, Name: Diethyltrichloromethylphosphonate, the publication is Zhurnal Obshchei Khimii (1974), 44(11), 2419-22, database is CAplus.

(RO)2(Cl3C)PO (R = C1-5 n-alkyl) were obtained in 52.9-87.5% yields by boiling P(OR)3 8 hr with CCl4. Addnl. obtained were the corresponding R(Cl3C)P(O)(OR). Treatment of PrP(O)(OEt)2 with CCl4 14 hr at 50-70° gave 61% R(Cl3C)P(O)(OR1) (I; R = Pr, R1 = Et). Analogously obtained were 39 and 75% I (R = Bu, R1 = pentyl; R = Ph, R1 = Et).

Zhurnal Obshchei Khimii published new progress about 866-23-9. 866-23-9 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is Diethyltrichloromethylphosphonate, and the molecular formula is C5H10Cl3O3P, Name: Diethyltrichloromethylphosphonate.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Abd El-Meguid, Eman A. published the artcileSynthesis and antimicrobial evaluation of some novel sulfamoyl and triazole derivatives incorporating a 4-benzoimidazol-2-yl moiety, Related Products of chlorides-buliding-blocks, the publication is International Journal of Pharmacy and Technology (2015), 7(3), 10014-10028, database is CAplus.

In this study 15 novel benzoimidazole compounds were synthesized in order to investigate their possible antibacterial and antifungal activity. Two different Gram-pos. and two different Gram-neg. bacterial strains were used in antibacterial activity tests. Antifungal activity tests were also performed against two different fungal strains. Most of the test compounds found to be significantly effective against Gram-pos., Gram-neg. bacterial strains and antifungal strains.

International Journal of Pharmacy and Technology published new progress about 21286-54-4. 21286-54-4 belongs to chlorides-buliding-blocks, auxiliary class Chiral,Chloride,Sulfonyl chlorides,Aliphatic cyclic hydrocarbon,Ketone, name is ((1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride, and the molecular formula is C10H15ClO3S, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Abd El-Meguid, Eman Ali published the artcileDiscovery of some novel benzothiazole derivatives as VEGFR-2 inhibitors, Quality Control of 21286-54-4, the publication is International Journal of Pharmacy and Technology (2015), 7(3), 10040-10055, database is CAplus.

A series of benzothiazole derivatives were prepared by condensation of 5-amino-1-(4-benzothiazol-2-yl-benzoyl)-1H-pyrazole-4-carbonitrile (1) and/or 5-amino-1-(4-benzothiazol-2-yl-benzoyl)-1H-pyrazole-4-carboxylic acid hydrazide (6) with different electrophilic and nucleophilic reagents. All of the newly synthesized compounds have been evaluated for their potential cytotoxicity against breast cancer cell line (MCF-7); compounds 5c, 8b and 8c are more potent than tamoxifen while compounds 5b and 8a are equipotent to tamoxifen. These results were consistent with percentage of inhibition values against human VEGF compared with control untreated cells.

International Journal of Pharmacy and Technology published new progress about 21286-54-4. 21286-54-4 belongs to chlorides-buliding-blocks, auxiliary class Chiral,Chloride,Sulfonyl chlorides,Aliphatic cyclic hydrocarbon,Ketone, name is ((1S,4R)-7,7-Dimethyl-2-oxobicyclo[2.2.1]heptan-1-yl)methanesulfonyl chloride, and the molecular formula is C10H15ClO3S, Quality Control of 21286-54-4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Abdulla, Riaz F. published the artcileMorpholines. V. Synthesis and properties of some 2-substituted 3-oxo-4H-1,4-oxazines, Computed Properties of 18791-02-1, the publication is Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, Biochemie, Biophysik, Biologie (1972), 27(12), 1465-70, database is CAplus.

Cyclodehydrochlorination of p-RC6H4N(COCHCl2)CH2COC6H4N-O2-p with Me3COK in Me2SO gave the title compounds (I; R = H or EtO2C; X = OH), which reacted with SOCl2 to give I (X = Cl) (II). Solvolysis with MeOH or amination of II with R21NH gave I (X = MeO or NR21, NR21 = ethyleneimino, 1-pyrrolidinyl, or piperidino).

Zeitschrift fuer Naturforschung, Teil B: Anorganische Chemie, Organische Chemie, Biochemie, Biophysik, Biologie published new progress about 18791-02-1. 18791-02-1 belongs to chlorides-buliding-blocks, auxiliary class Aliphatic Chain, name is 2,3-Dibromopropionylchloride, and the molecular formula is C3H3Br2ClO, Computed Properties of 18791-02-1.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics