Tag: M.W=300-350

Han, Shuaiyuan published the artcileReversible Complexation Mediated Living Radical Polymerization Using Tetraalkylammonium Chloride Catalysts, Category: chlorides-buliding-blocks, the publication is Macromolecular Rapid Communications, database is CAplus and MEDLINE.

The paper reports the first use of organic chloride salts as catalysts for reversible complexation mediated living radical polymerization Owing to the strong halogen-bond forming ability of Cl^–, the studied four tetraalkylammonium chloride catalysts (R₄N⁺Cl^–) successfully control the polymerizations of Me methacrylate, yielding polymers with low dispersities up to high monomer conversion (>90%). Benzyldodecyldimethylammonium chloride is further exploited to other methacrylates and yields low-dispersity block copolymers. Advantages of the chloride salt catalysts are wide monomer scope, good livingness, accessibility to block copolymers, and good solubility in organic media. Because of the good solubility, the use of the chloride salt catalysts can prevent agglomeration of catalysts on reactor walls in organic media, which is an industrially attractive feature. Among halide anions, chloride anion is the most abundant and least expensive halide anion, and therefore, the use of the chloride salt catalysts may lower the cost of the polymerization

Macromolecular Rapid Communications published new progress about 23616-79-7. 23616-79-7 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst, name is N-Benzyl-N,N-dibutylbutan-1-aminium chloride, and the molecular formula is C19H34ClN, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Lunagariya, Jignesh published the artcileDesign and synthesis of analogues of marine natural product galaxamide, an N-methylated cyclic pentapeptide, as potential anti-tumor agent in vitro, HPLC of Formula: 42074-68-0, the publication is Marine Drugs (2016), 14(9), 161/1-161/22, database is CAplus and MEDLINE.

Herein, we report design and synthesis of novel 26 galaxamide analogs with N-methylated cyclo-pentapeptide, and their in vitro anti-tumor activity towards the panel of human tumor cell line, such as, A549, A549/DPP, HepG2 and SMMC-7721 using MTT assay. We have also investigated the effect of galaxamide and its representative analogs on growth, cell-cycle phases, and induction of apoptosis in SMMC-7721 cells in vitro. Reckon with the significance of conformational space and N-Me aminoacid (aa) comprising this compound template, we designed the analogs with modification in N-Me-aa position, change in aa configuration from l to d aa and substitute one Leu-aa to d/l Phe-aa residue with resp. to the parent structure. The efficient solid phase parallel synthesis approach is employed for the linear pentapeptide residue containing N-Me aa, followed by solution phase macrocyclisation to afford target cyclo pentapeptide compounds In the present study, all galaxamide analogs exhibited growth inhibition in A549, A549/DPP, SMMC-7721 and HepG2 cell lines. Compounds 6, 18, and 22 exhibited interesting activities towards all cell line tested, while Compounds 1, 4, 15, and 22 showed strong activity towards SMMC-7221 cell line in the range of 1-2 μg/mL IC50. Flow cytometry experiment revealed that galaxamide analogs namely Compounds 6, 18, and 22 induced concentration dependent SMMC-7721 cell apoptosis after 48 h. These compounds induced G0/G1 phase cell-cycle arrest and morphol. changes indicating induction of apoptosis. Thus, findings of our study suggest that the galaxamide and its analogs 6, 18 and 22 exerted growth inhibitory effect on SMMC-7721 cells by arresting the cell cycle in the G0/G1 phase and inducing apoptosis. Compound 1 showed promising anti-tumor activity towards SMMC-7721 cancer cell line, which is 9 and 10 fold higher than galaxamide and reference DPP (cisplatin), resp.

Marine Drugs published new progress about 42074-68-0. 42074-68-0 belongs to chlorides-buliding-blocks, auxiliary class Chloride,Benzyl chloride,Benzene, name is 2-Chlorotrityl chloride, and the molecular formula is C19H14Cl2, HPLC of Formula: 42074-68-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Cao, Xinhua published the artcileFluorescence and Morphology Modulation in a Photochromic Diarylethene Self-Assembly System, COA of Formula: C15H14Cl2S2, the publication is Langmuir (2011), 27(8), 5090-5097, database is CAplus and MEDLINE.

Switchable supramol. self-assemblies on the basis of interaction between melamine group containing photochromic diarylethene unit (DTE) and naphthalimide derivate (1) were designed and fabricated. 1 can gelate several aprotic solvents with different morphologies. The gel turned into partial gel in Et acetate with the addition of DTE as a guest mol. Both the absorption and fluorescence spectra of the assembly can be reversibly switched by alternating UV/visible light irradiation Meanwhile, the morphol. of the coassembly of 1₂·DTE changed to film from original pieces of gel 1 in Et acetate. When 1₂·DTE was irradiated by UV light, the film morphol. was converted into aggregated flakes. Moreover, the surface wettability of the complex can also be switched by light irradiation The photochromic diarylethene unit is able to modulate the fluorescence and morphol. of the assembled system only by virtue of light irradiation Therefore, these results provide further insights into fluorescence and morphol. controlling, especially application in upscale smart responsive materials.

Langmuir published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, COA of Formula: C15H14Cl2S2.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Zheng, Haiyan published the artcileOptic and proton dual-control of fluorescence of Rhodamine based on photochromic diarylethene: mimicking the performance of an integrated logic gate, SDS of cas: 219537-97-0, the publication is Tetrahedron Letters (2009), 50(14), 1588-1592, database is CAplus.

A proton and optic dual-responsive fluorescence switch dyad which contains Rhodamine and photochromic diarylethene has been designed and an integrated logic circuit at the mol. level has been proposed.

Tetrahedron Letters published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C9H9N3, SDS of cas: 219537-97-0.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Baez, Jose E. published the artcileSynthesis of Poly(methylene-b-ε-caprolactone) and Poly(ε-caprolactone) with Linear Alkyl End Groups: Synthesis, Characterization, Phase Behavior, and Compatibilization Efficacy, Quality Control of 23616-79-7, the publication is Industrial & Engineering Chemistry Research (2017), 56(37), 10366-10383, database is CAplus.

Diblock copolymers of poly(methylene-b-ε-caprolactone) (PM-b-PCL) were synthesized in two steps: (a) polyhomologation, to obtain following oxidative cleavage of the carbon-boron, (PM, block1), an α-hydroxyl-ω-Me polymethylene (PMOH, CH3-[CH2]m-OH). Following transfer reaction to the ring-opening polymerization catalyst and (b) ring-opening polymerization (ROP) of ε-caprolactone (CL) (PCL, block2). In addition, a series of homopolymers derived from poly(ε-caprolactone) (PCL) oligoesters containing an end group of docosyl (CH3-[CH2]21- or C22) (C22-PCL) were obtained as a model to compare their phys. properties by DSC with those of PM-b-PCL. The oligomers derived from PM-b-PCL and C22-PCL were characterized by 1H and 13C NMR, AFM, DSC, GPC and MALDI-TOF. PM-b-PCL and C22-PCL were evaluated as compatibilizers for PE/PCL polymer blends. Identification and anal. of optimized blocks of PM-b-PCL by POM and SEM showed improved mixing of PE/PCL blends.

Industrial & Engineering Chemistry Research published new progress about 23616-79-7. 23616-79-7 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst, name is N-Benzyl-N,N-dibutylbutan-1-aminium chloride, and the molecular formula is C19H34ClN, Quality Control of 23616-79-7.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Liu, Taoping published the artcileGeneral and highly efficient fluorinated-N-heterocyclic carbene-based catalysts for the palladium-catalyzed Suzuki-Miyaura reaction, Recommanded Product: 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, the publication is Tetrahedron (2012), 68(32), 6535-6547, database is CAplus.

A general and highly efficient trifluoromethylated-N-heterocyclic carbene (NHC)-based catalyst (I) for the palladium-catalyzed Suzuki-Miyaura reaction was reported. In the presence of the catalyst, reactions of non-activated aryl chlorides and triflates with aryl boronic acids occurred at room temperature with good to excellent yields (63-98%). In addition, catalysts generated from a combination of Pd(OAc)₂/imidazolium salt I is not only effective for the coupling of heteroaryl boronic acid with aryl halides and heteroaryl halides, but also efficient for coupling of other heteroaryl halides and heteroaryl boronic acids. Finally, the catalyst is highly effective for Suzuki-Miyaura reaction of aryl bromides and chlorides with 0.01-0.1 mol % loading if the temperature was raised at refluxed THF/H₂O.

Tetrahedron published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, Recommanded Product: 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Hou, Lili published the artcileReversible Photochemical Control of Singlet Oxygen Generation Using Diarylethene Photochromic Switches, Safety of 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, the publication is Journal of the American Chemical Society (2014), 136(3), 910-913, database is CAplus and MEDLINE.

Reversible noninvasive control over the generation of singlet oxygen is demonstrated in a bicomponent system comprising a diarylethene photochromic switch and a porphyrin photosensitizer by selective irradiation at distinct wavelengths. The efficient generation of singlet oxygen by the photosensitizer is observed when the diarylethene unit is in the colorless open form. Singlet oxygen generation is not observed when the diarylethene is converted to the closed form. Irradiation of the closed form with visible light (>470 nm) leads to full recovery of the singlet oxygen generating ability of the porphyrin sensitizer.

Journal of the American Chemical Society published new progress about 219537-97-0. 219537-97-0 belongs to chlorides-buliding-blocks, auxiliary class Fused/Partially Saturated Cycles,Cyclopentenes, name is 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene, and the molecular formula is C15H14Cl2S2, Safety of 5-Chloro-3-[2-(5-chloro-2-methylthien-3-yl)cyclopent-1-en-1-yl]-2-methylthiophene.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Jin, Ling published the artcileAdditives structure in electroreduction of oxalic acid, Application of N-Benzyl-N,N-dibutylbutan-1-aminium chloride, the publication is Huagong Xuebao (Chinese Edition) (2010), 61(S1), 86-90, database is CAplus.

In this paper, as the background of the preparation of glyoxylic acid by the electroreduction of oxalic acid on lead electrodes, the effects of additives structure on electrode reaction have been studied. The results show that the cation of the additives has the most influence on current efficiency and the reaction selectivity. Furthermore, cation radicle is more sym. or the longest alkyl chain is shorter, the current efficiency and the reaction selectivity are higher. The tetra-Et quaternary ammonium salt has the best active effect.

Huagong Xuebao (Chinese Edition) published new progress about 23616-79-7. 23616-79-7 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst, name is N-Benzyl-N,N-dibutylbutan-1-aminium chloride, and the molecular formula is C19H34ClN, Application of N-Benzyl-N,N-dibutylbutan-1-aminium chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Guo, Rui-Ting published the artcileRhodium-Catalyzed ortho-Selective Carbene C-H Insertion of Unprotected Phenols Directed by a Transient Oxonium Ylide Intermediate, Computed Properties of 23616-79-7, the publication is Organic Letters (2020), 22(3), 908-913, database is CAplus and MEDLINE.

Ortho-Selective carbene C-H insertion of unprotected phenols is achieved with di-Me diazomalonate under the catalysis of [Rh(COD)Cl]₂. After the C-H insertion, subsequent cyclization and electrophilic addition of another carbene mol. affords tris-carboxylate-substituted 2-benzofuranones as the final reaction products. The enantioselective variant has been developed with the use of chiral diene ligands. Mechanistic experiments indicate that a transient oxonium ylide directing group might be responsible for the regiocontrol at the C-H activation step.

Organic Letters published new progress about 23616-79-7. 23616-79-7 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst, name is N-Benzyl-N,N-dibutylbutan-1-aminium chloride, and the molecular formula is C19H34ClN, Computed Properties of 23616-79-7.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Deng, Yu published the artcileRecovery of rare earths in different media with novel dicarboxylate based ionic liquid and application to recycle SmCo magnets, Recommanded Product: N-Benzyl-N,N-dibutylbutan-1-aminium chloride, the publication is Hydrometallurgy (2022), 105844, database is CAplus.

Recovery and separation of rare earth elements was highly crucial but difficult. In this study, a well-designed new ionic liquid named as benzyltributylammonium decanedioate ([N_444Bn]₂[SA]) was developed to extract rare earths and sep. Sm(III) from the spent SmCo magnets in acetate medium for the first time. To exhibit the superiority of acetate medium, the extraction of Nd(III) and La(III) in three different media were comparatively investigated under different conditions, including equilibrium time, initial pH of aqueous solution, rare earth concentration, extractant concentration, salting-out agent concentration and extraction temperature The results revealed that the better extractabilities of La(III) were observed in acetate medium rather than those in chloride medium (i.e., 97.6% vs. 78.6%), which may be attributed to the low-hydrated nature of acetate ions. Importantly, the back-extraction experiments indicated that 91.4% Nd(III) can be stripped from [N_444Bn]₂[SA] by using 1.5 mol/L HOAc, revealing the outstanding reusability of ionic liquid in the industrial separation-stripping cycles. Furthermore, the ion association mechanism was proposed to describe the extraction behavior and confirmed by the slope anal. and FT-IR characterizations in three media. In terms of the SmCoCu mixture separation, the maximal separation factor of Sm(III)/Co(II) was calculated as 3078 in simulated solution Impressively, the recovery of Sm(III) from the actual SmCo magnets by our dicarboxylate-type ionic liquid was also successfully achieved with a recycling rate of 96.8% and a Sm(III)/Co(II) selectivity of 148, which exhibited the potential application in the separation of Sm(III) from the spent SmCo magnets.

Hydrometallurgy published new progress about 23616-79-7. 23616-79-7 belongs to chlorides-buliding-blocks, auxiliary class Phase Transfer Catalyst, name is N-Benzyl-N,N-dibutylbutan-1-aminium chloride, and the molecular formula is C19H34ClN, Recommanded Product: N-Benzyl-N,N-dibutylbutan-1-aminium chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics