Tag: M.W=600-700

Zhebentyaev, A. I. published the artcileSpectrophotometric determination of decamethoxin, Category: chlorides-buliding-blocks, the publication is Vestsi Akademii Navuk BSSR, Seryya Khimichnykh Navuk (1982), 25-7, database is CAplus.

Decamethoxin was determined by spectrophotometry by measuring the absorbance of its 1:2 associate with phloxine at 530 nm in a citrate buffer (pH 1.5) in 10% EtOH. The stability constant of the associate is 2.3 × 10¹⁰. Various derivatives of quaternary ammonium hydroxides did not interfere. The detection limit is 0.4 μg/mL.

Vestsi Akademii Navuk BSSR, Seryya Khimichnykh Navuk published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C24H29N5O3, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Zhornyak, O. I. published the artcileAnalysis of the antimicrobial activity of antiseptic tablets to microorganisms, Product Details of C38H74Cl2N2O4, the publication is Anali Mechnikivs’kogo Institutu (2012), 51-54, database is CAplus.

Antimicrobial activity of antiseptic tablets septefril, sebidin, septolette, ephisol, adzhisept results have been given in this article. Research results point to great perspective of septefril, sebidin, septolette, ephisol, adzhisept antiseptic usage for treatment and prophylaxis inflammatory-purulent diseases.

Anali Mechnikivs’kogo Institutu published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C13H10O2, Product Details of C38H74Cl2N2O4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Rebrova, R. N. published the artcileComparative study of the effect of decamine and decamethoxine on fungi of the genus Candida, diphtheria bacteria and pathogenic staphylococci, Formula: C38H74Cl2N2O4, the publication is Vestnik Dermatologii i Venerologii (1971), 45(11), 51-2, database is CAplus and MEDLINE.

Decamine [522-51-0] had a stronger fungistatic effect against Candida albicans than did decamethoxine (I) [38146-42-8], but I was more effective than decamine in preventing the growth of diphtheria bacteria and pathogenic staphylococci. I may be useful in treating diseases caused or complicated by diphtheria or staphylococci organisms.

Vestnik Dermatologii i Venerologii published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C38H74Cl2N2O4, Formula: C38H74Cl2N2O4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Vievski, A. N. published the artcileNew microbicides containing quaternary ammonium derivatives, Quality Control of 38146-42-8, the publication is Mikologiya i Fitopatologiya (1993), 27(2), 48-50, database is CAplus.

Two new quaternary ammonium compounds, decaversene and decamethoxine, were found to display antimicrobial activity against Candida albicans, Aspergillus niger, and Pseudomonas aeruginosa. The antimicrobial activity of these compounds was significantly potentiated by the anion Trilon B.

Mikologiya i Fitopatologiya published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C10H10O4, Quality Control of 38146-42-8.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Vievsky, A. N. published the artcileSynergistic effect of quaternary ammonium derivatives and nitrate reduction inhibitors on Pseudomonas aeruginosa, HPLC of Formula: 38146-42-8, the publication is Mikrobiologichnii Zhurnal (1994), 56(4), 16-20, database is CAplus.

The ability of zinc chloride, copper sulfate, aluminum nitrate and sodium fluoride to inhibit the nitrate reduction of Pseudomonas correlated with their potentiating influence on the antimicrobial activity of decamethoxin, a quaternary ammonium derivative Doses of zinc chloride (0.01-0.04%), copper sulfate (0.04%), aluminum nitrate (0.04%), and sodium fluoride (0.05-0.1%) able to inhibit effectively the reduction of anions of nitric acid decreased the minimal inhibitory concentration of decamethoxin against Pseudomonas strain ATCC 27853 to 0.15-10 mg/mL and the minimal bactericidal concentration to 0.20-10 mg/mL in comparison with 15.6 and 60.4 mg/mL in the control without potentiators.

Mikrobiologichnii Zhurnal published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C13H14N2O, HPLC of Formula: 38146-42-8.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Volyanskii, Y. L. published the artcileEffect of decametoxin, some quinoline and phenol derivatives on the main growth and propagation parameters of Staphylococci and Escherichia coli., Quality Control of 38146-42-8, the publication is Trudy – Tomskii Nauchno-Issledovatel’skii Institut Vaktsin i Syvorotok, Tomskii Meditsinskii Institut [i] Tomskoe Otdelenie Vserossiiskogo Nauchno-Meditsinskogo Obshchestva Mikrobiologov, Epidemiologov i Parazitologov (1981), 260-3, database is CAplus.

While minimal concentrations of decametoxin and of a quinoline deriv (comp. 264) initially gradually decreased the optical d. of staphylococcal cultures and those of coliform bacteria, a Cl-containing phenolic compound (compound 492) caused no changes in the optical d. of the cultures. However, between the second and fourth h of incubation in presence of first 2 compounds the level of optical d. was stabilized and thereafter increased, the increase being associated with increasing rate of biomass accumulation in the exponential phase. The increase in staphylococcal biomass at that phase under the action of decametoxin at subbacteriostatic concentration was slower than that at min. inhibitory concentration The lag-phase in control and in the presence of the first 2 compounds at bacteriostatic and subbacteriostatic concentrations was the same, while at similar concentrations compound 492 increased the lag-phase ∼2-fold. Compound 492 at min. bacteriostatic and subbacteriostatic rates was neutral with regard to substrate utilization by Escherichia coli, while the first 2 compounds by activating and inducing enzymic systems in the bacteria permitted utilizing the carbohydrates present in the medium, which probably resulted in the intensive biomass increment observed in the exponential phase.

Trudy – Tomskii Nauchno-Issledovatel’skii Institut Vaktsin i Syvorotok, Tomskii Meditsinskii Institut [i] Tomskoe Otdelenie Vserossiiskogo Nauchno-Meditsinskogo Obshchestva Mikrobiologov, Epidemiologov i Parazitologov published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C20H28B2O4S2, Quality Control of 38146-42-8.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Palii, G. K. published the artcileEffect of decamethylene-1,10-bis(N-dimethylcarbomenthoxymethylammonium) dichloride on agglutinin and complement titers under experimental conditions, Application of N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, the publication is Immunologiya (Kiev) (1972), 133-6, database is CAplus.

Decamethylene-1,10-bis(dimethylcarbomenthoxymethylammonium) dichloride (I) [38146-42-8] administered s.c. to rabbits at 1 or 2 mg/kg daily for 14 days during immunization with typhoid vaccine did not inhibit the manufacture of agglutinins and increased complement titer. Similar administration of I for 14 days after termination of immunization did not affect complement or agglutinin levels of the blood.

Immunologiya (Kiev) published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C38H74Cl2N2O4, Application of N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Palii, G. K. published the artcileDevelopment of resistance of Candida albicans to chemotherapeutic preparations, Related Products of chlorides-buliding-blocks, the publication is Trudy Krymskogo Gosudarstvennogo Meditsinskogo Instituta (1974), 38-40, database is CAplus.

C. albicans grown in nutrient medium containing increasing concentrations of decamine [17349-05-2] and decamethoxin [38146-42-8] gradually developed resistance to these fungicides but retained their sensitivity to levorin [11014-70-3]. Morphol. and culture changes and decreased rates of carbohydrate catabolism accompanied the development of Candida resistance to decamine and decamethoxin.

Trudy Krymskogo Gosudarstvennogo Meditsinskogo Instituta published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C38H74Cl2N2O4, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Droniak, M. M. published the artcileApplication of extranil for lavage of abdominal cavity in patients with postoperative peritonitis, Product Details of C38H74Cl2N2O4, the publication is Pharma Innovation (2019), 8(7-H), 398-400, database is CAplus.

Application of lavage of the abdominal cavity with extranil in patients with postoperative peritonitis promotes regression of the inflammatory process in the abdominal cavity and manifestations of endotoxicosis and systemic inflammation. Depending on the curative tactics of the postoperative period, all patients were divided into two groups: – observation group (OG) – 26 patients with postoperative peritonitis where in the postoperative period was used lavage of the abdominal cavity with a solution for peritoneal dialysis extranil; – control group (CG) – 30 patients with postoperative peritonitis, in complex treatment of which extranil was not used. The severity of condition in patients with PP was rated with the SAPS II scale. The presence and severity of manifestations of MOF in patients with PP was determined by the SOFA scale. The level of endogenous intoxication was evaluated by the amount in blood of serum middle-mass mols., C-reactive protein, and leukocyte index of intoxication. During relaparotomy lavage of abdominal cavity was done twice with 2-3 L of a 0, 02% solution of decamethoxin at a temperature of 30-35° C. After removal of the remains of the drug from the abdominal cavity, 2 L of Extranil with a temperature of 37,0C, the active substance of which is icodextrin, but not glucose, so it is not a nutrient for microorganisms, but has an antimicrobial effect due to hyperosmolarity and influence on the peritoneum by increasing its adsorption properties. After that the abdominal cavity was drained from four points by polychlorinated biphenyl tubes, which were fixed to the skin and closed for 6 h. The use of the proposed method in patients with postoperative peritonitis can reduce the frequency of postoperative complications and reduce the mortality rate by 1,5 times. The total mortality rate among all patients with peritonitis was 13, 2% in the control group and 7, 6% in the observation group.

Pharma Innovation published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C38H74Cl2N2O4, Product Details of C38H74Cl2N2O4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Zhernosek, A. K. published the artcileEffect of polar organic solvents on the extraction of quaternary ammonium compounds associates with fluorescein halo derivatives, Category: chlorides-buliding-blocks, the publication is Vestsi Akademii Navuk Belarusi, Seryya Khimichnykh Navuk (1997), 11-15, database is CAplus.

The effect of structure of quaternary ammonium compounds (decamine, decamethoxin, ethonium, qualidil, berberine disulfate) and polar organic solvent nature on extraction of ion associates of QAC with fluorescein halo derivatives (eosin, phloxine A) by chloroform has been studied.

Vestsi Akademii Navuk Belarusi, Seryya Khimichnykh Navuk published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C3H7NO2, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics