Tag: M.W=600-700

Kovalchuk, Valentine published the artcileNaturally drug-loaded chitin: isolation and applications, Category: chlorides-buliding-blocks, the publication is Marine Drugs (2019), 17(10), 574, database is CAplus and MEDLINE.

Naturally occurring three-dimensional (3D) biopolymer-based matrixes that can be used in different biomedical applications are sustainable alternatives to various artificial 3D materials. For this purpose, chitin-based structures from marine sponges are very promising substitutes. Marine sponges from the order Verongiida (class Demospongiae) are typical examples of demosponges with well-developed chitinous skeletons. In particular, species belonging to the family Ianthellidae possess chitinous, flat, fan-like fibrous skeletons with a unique, microporous 3D architecture that makes them particularly interesting for applications. In this work, we focus our attention on the demosponge Ianthella flabelliformis (Linnaeus, 1759) for simultaneous extraction of both naturally occurring (“ready-to-use”) chitin scaffolds, and biol. active bromotyrosines which are recognized as potential antibiotic, antitumor, and marine antifouling substances. We show that selected bromotyrosines are located within pigmental cells which, however, are localized within chitinous skeletal fibers of I. flabelliformis. A two-step reaction provides two products: treatment with methanol extracts the bromotyrosine compounds bastadin 25 and araplysillin-I N20 sulfamate, and a subsequent treatment with acetic acid and sodium hydroxide exposes the 3D chitinous scaffold. This scaffold is a mesh-like structure, which retains its capillary network, and its use as a potential drug delivery biomaterial was examined for the first time. The results demonstrate that sponge-derived chitin scaffolds, impregnated with decamethoxine, effectively inhibit growth of the human pathogen Staphylococcus aureus in an agar diffusion assay.

Marine Drugs published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C38H74Cl2N2O4, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Palii, G. K. published the artcileSensitivity of microflora isolated from babies with respiratory tract diseases to decamethoxin and antibiotics, Category: chlorides-buliding-blocks, the publication is Mikrobiologichnii Zhurnal (1934-1977) (1974), 36(3), 347-9, database is CAplus.

Staphylococcal strains, isolated from pharynx, skin, and feces of babies with respiratory tract diseases, were sensitive to decamethoxin (I) [38146-42-8] (0.12-7.8 μg/ml). However, most of the 118 strains were resistant to penicillin [1406-05-9], streptomycin [57-92-1], erythromycin [114-07-8], tetracycline [60-54-8], oxytetracycline [79-57-2], chlortetracycline [57-62-5], and levomycetin [56-75-7].

Mikrobiologichnii Zhurnal (1934-1977) published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C38H74Cl2N2O4, Category: chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Volyanskii, Yu. L. published the artcileEffect of decametoxin on pathogenic staphylococci, Name: N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, the publication is Mikrobiologichnii Zhurnal (1934-1977) (1971), 33(4), 503-6, database is CAplus.

The bactericidal concentrations of decametoxin, a derivative of decamethylenediamine [646-25-3], tested on 648 pathogenic strains of staphylococci ranged between 0.125 and 50 μg/ml. At 2.5 and 25 μg/ml decametoxin decreased the activity of catalase and peroxidase in Staphylococcus aureus.

Mikrobiologichnii Zhurnal (1934-1977) published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C7H5Br2F, Name: N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Mar’yanchik, I. V. published the artcileQuantitative determination of decamethoxine in sodium sulfapyridazine eyedrops, Quality Control of 38146-42-8, the publication is Pharmaceutical Chemistry Journal (Translation of Khimiko-Farmatsevticheskii Zhurnal) (2000), 34(8), 445-447, database is CAplus.

Decamethoxine (I), or 1,10-decamethylene-bis[N-dimethyl(carbomethoxymethyl)ammonium]dichloride, was suggested for use as a conservant additive in previously developed sodium sulfapyridazine (II) eyedrops. Strict requirements posed on the quality of ophthalmol. preparation necessitate thorough quant. monitoring of all eyedrop components, including the conservant. The proposed method was used for the quant. anal. of conservant I in eyedrops II packed in dropping bottles made of poly(ethylene). The measurements were performed in the course of aging under natural storage conditions. The content of I in the preparation gradually increases on storage, in proportion to the water lost via the bottle walls. This behavior was retained over the entire observation time of 5.5 yr.

Pharmaceutical Chemistry Journal (Translation of Khimiko-Farmatsevticheskii Zhurnal) published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C38H74Cl2N2O4, Quality Control of 38146-42-8.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Boryak, O. A. published the artcileBinding of two cationic compounds with graphene oxide: comparative analysis and observation of synergetic effect, Synthetic Route of 38146-42-8, the publication is Functional Materials (2021), 28(3), 450-462, database is CAplus.

The present paper reports on the results of the joint interaction of two organic cationic compounds of different structure and nature, namely bisquaternary ammonium decamethoxinum (Dec) with flexible dication and methylene blue (MB) with heterocyclic planar cation, with graphene oxide (GO) in aqueous dispersion. The qual. differences in the 3D structures of GO modified in binary (GO + Dec), (GO + MB) and ternary (GO + Dec + MB) systems were observed and described on the basis of the UV-vis spectral anal. of the systems. On mixing the components of the binary (GO + Dec) system, a rather rapid gelation of GO dispersion was observed The appearance of binary (GO + MB) system showed dependence on GO to MB ratio: at low GO content, MB-induced coagulation of GO to tiny bluish flakes took place followed by their sedimentation with time while at high GO content, the GO complexes with MB preserved solubility in water. The result of the joint addition of both Dec and MB to GO dispersion differed qual. from the above results of action of individual components. On creation of the (GO + Dec + MB) ternary system rapid flocculation of all components of the system was observed resulting in the formation of dark residue surfacing over the purified decolorized liquid UV-vis spectra of the liquid phase showed suppression of the lines of all components or their complexes practically to the baseline. The compression of (GO + Dec + MB) composite to flocs is explained by the matching of the size of MB cation to that of Dec dication linker, which provides tight filling of the gaps between GO sheets. The observed flocculation effect in the (GO + Dec + MB) system may be of practical interest in the development of nanocomposite and sorption materials. Information on the features of GO interactions with organic cations differing in structure may be useful for advances in drug delivery problem.

Functional Materials published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C38H74Cl2N2O4, Synthetic Route of 38146-42-8.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Katsev, A. M. published the artcileStudy of interactions between cationic surface-active antiseptics and serum albumin by bacterial bioluminescence, Application of N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, the publication is Klinicheskaya Laboratornaya Diagnostika (2002), 39-41, database is CAplus and MEDLINE.

Human serum albumin binding of cationic surface-active antiseptics was studied using a Photobacterium phosphoreum K3 strain isolated in the Black Sea. Binding of cationic surface-active proteins to serum albumin led to disappearance of toxic and antibacterial characteristics of miramistin, ethonium, and decametoxin, but not chlorhexidine. The activity of chlorohexidine was reduced by 45-8% in the presence of albumin. Albumin binding capacity towards miramistin was 7.0-8.7%, towards ethonium 8.2-10%, and towards decametoxin 2.4-3%.

Klinicheskaya Laboratornaya Diagnostika published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C38H74Cl2N2O4, Application of N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Savelyev, Yuri V. published the artcileNovel polyurethane foams with biological activity and based composites, Formula: C38H74Cl2N2O4, the publication is Rigas Tehniskas Universitates Zinatniskie Raksti, Serija 1: Materialzinatne un Lietiska Kimija (2007), 107-114, database is CAplus.

New polyurethane foams with different formulations were synthesized. Created polyurethane foams are characterized by fungicidal activity against mold and yeast-like fungi of the genera: Aspergillis, Chaetomium, Penicillium, Trichoderma, and Candida and bactericidal activity in regards to some pathogenic bacteria: Staphylococcus aureus, E. coli, Klebsiella pneumoniae, Proteus. Polyurethane foams are characterized by the compatibility with organism tissues – fast germination of the tissues through the polyurethane foam samples from 1 up to 3 mo and practically absence of the united-tissued capsule and cell’s reaction. The polyurethane foam was used as supporting matrixes of granular solid adsorbents. The parameters of porous frame (pore volume on benzene W_s and sp. surface area S_BET) of the polyurethane foam-activated carbon sorbic composite systems at optimum ratios differ a little from the same indexes of virgin carbon and have practically identical tendency to change. These samples are possessed stability for fungi attack.

Rigas Tehniskas Universitates Zinatniskie Raksti, Serija 1: Materialzinatne un Lietiska Kimija published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C38H74Cl2N2O4, Formula: C38H74Cl2N2O4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Vislohuzova, Tetiana published the artcileStudy of biodegradation, biocompatibility and bactericidal activity of film materials with tiamulin fumarate based on polyurethaneurea, Related Products of chlorides-buliding-blocks, the publication is Chemistry & Chemical Technology (2020), 14(3), 318-326, database is CAplus.

The influence of the model biol. medium 199 on the structure and properties of film materials with tiamulin fumarate based on polyurethaneurea containing in its structure the hydrophilic fragments of the copolymer of N-vinylpyrrolidone with vinyl acetate and vinyl alc. has been investigated. According to IR spectroscopy, under the influence of the biol. medium 199 there are processes of biodegradation of polymer materials which are accompanied by a decrease in the intensity of the absorption band νC=O of vinylpyrrolidone ring. It is established that the introduction of tiamulin fumarate into polyurethaneurea facilitates their biodegradation, as evidenced by a decrease of the tensile strength (1.28-2.38 times) and a relative elongation at break (1.36-1.82 times) after incubation in the biol. medium 199 by physico-mech. tests. The tissue culture method has established the biocompatibility of film materials with tiamulin fumarate. According to the results of microbiol. studies, bactericidal properties were observed in relation to the bacteria Staphylococcus aureus and Escherichia coli. It allows using them for production of drainage in abdominal surgery.

Chemistry & Chemical Technology published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C4H6O3, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Egorov, V. V. published the artcileDetermination of cationic surface-active antiseptics by ion-selective electrodes, Formula: C38H74Cl2N2O4, the publication is Journal of Analytical Chemistry (Translation of Zhurnal Analiticheskoi Khimii) (1996), 51(10), 986-988, database is CAplus.

It is shown that low concentrations of surface-active antiseptics can be determined by potentiometric precipitation titration with sodium tetraphenylborate (in the case of cetylpyridinium chloride, chlorhexidine bigluconate, and decamethoxin) or with sodium picrate (in the case of ethonium) in solutions of inorganic salts with the use of ion-selective electrodes for detecting the equivalence point.

Journal of Analytical Chemistry (Translation of Zhurnal Analiticheskoi Khimii) published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C38H74Cl2N2O4, Formula: C38H74Cl2N2O4.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics

Davtyan, Lena published the artcileTechnological aspects of dental medical films with chlorhexidine and decamethoxine, Related Products of chlorides-buliding-blocks, the publication is International Journal of Pharmacy and Technology (2015), 7(1), 8166-8173, database is CAplus.

The importance of polymers in medicine and technol. requires need for a detailed study of the properties not only of the polymer itself but also its interaction with organic solvents, water, plasticizers and others. In most cases, these same fluids themselves are solvents for the polymer therefore this interaction should be considered as the basis for polymer processing solutions through films.

International Journal of Pharmacy and Technology published new progress about 38146-42-8. 38146-42-8 belongs to chlorides-buliding-blocks, auxiliary class Achiral Phase-Transfer Catalysts, name is N1,N10-Bis(2-((2-isopropyl-5-methylcyclohexyl)oxy)-2-oxoethyl)-N1,N1,N10,N10-tetramethyldecane-1,10-diaminium chloride, and the molecular formula is C38H74Cl2N2O4, Related Products of chlorides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Chloride,
Chlorides – an overview | ScienceDirect Topics