M.W=650-700 Archives - Page 13 of 15 - Chlorides-buliding-blocks

Han, Zhengyu team published research on ACS Catalysis in 2021 | 12112-67-3

Application In Synthesis of 12112-67-3, Bis(1,5-cyclooctadiene)diiridium(I) is a useful research compound. Its molecular formula is C16H24Cl2Ir2-2 and its molecular weight is 671.7 g/mol. The purity is usually 95%.
Bis(1,5-cyclooctadiene)diiridium(I) Dichloride is a catalyst used in the iridium-catalyzed asymmetry hydrogenation of unfunctionalized exocyclic double carbon bonds. Also, it is used to test new NeoPHOX ligands derived from serine or threonine.
Bis(1,5-cyclooctadiene)diiridium(I) dichloride is an acid that can be prepared using a preparative method. It is an organometallic compound that can be used in the cross-coupling of activated terminal alkynes with aryl halides. Bis(1,5-cyclooctadiene)diiridium(I) dichloride has been synthesized by reacting furfural with chloride and acetonitrile. The ligand used was 2,2′-bipyridine. The reaction time to produce bis(1,5-cyclooctadiene)diiridium(I) dichloride is approximately three hours.
, 12112-67-3.

Chlorinated organic compounds are found in nearly every class of biomolecules. 12112-67-3, formula is C16H24Cl2Ir2, Name is Chloro(1,5-cyclooctadiene)iridium(I) dimer. Alkyl chlorides, as versatile building blocks in organic chemistry, are used in the preparation of alcohols, thioethers, alkenes, alkynes, esters, and Grignard reagents. Application In Synthesis of 12112-67-3.

Han, Zhengyu;Liu, Gang;Yang, Xuanliang;Dong, Xiu-Qin;Zhang, Xumu research published 《 Enantiodivergent Synthesis of Chiral Tetrahydroquinoline Derivatives via Ir-Catalyzed Asymmetric Hydrogenation: Solvent-Dependent Enantioselective Control and Mechanistic Investigations》, the research content is summarized as follows. Ir-catalyzed asym. hydrogenation of quinolines I (R = Me, Ph, naphthalen-2-yl, 2H-1,3-benzodioxol-5-yl, thiophen-3-yl, etc.; R¹ = H, Me, Et, n-Pr; R² = H, 5-Cl, 6-OMe, 7-Me, etc.) was developed, and both enantiomers of chiral tetrahydroquinoline derivatives ((R)/(S)/cis/trans)-II could be easily obtained, resp., in high yields with good enantioselectivities through the adjustment of reaction solvents (toluene/dioxane: up to 99% yield, 98% ee (R), TON = 680; EtOH: up to 99% yield, 94% ee (S), TON = 1680). It provided an efficient and simple synthetic strategy for the enantiodivergent synthesis of chiral tetrahydroquinolines ((R)/(S)/cis/trans)-II, and gram-scale asym. hydrogenation proceeded well with low-catalyst loading in these two reaction systems. A series of deuterium-labeling experiments, control experiments, and ¹H NMR and electrospray ionization-mass spectrometry experiments have been conducted, and a reasonable and possible reaction process was revealed on the basis of these useful observations.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Fukuyama, Takahide team published research on Synthesis in 2021 | 12112-67-3

Computed Properties of 12112-67-3, Bis(1,5-cyclooctadiene)diiridium(I) is a useful research compound. Its molecular formula is C16H24Cl2Ir2-2 and its molecular weight is 671.7 g/mol. The purity is usually 95%.
Bis(1,5-cyclooctadiene)diiridium(I) Dichloride is a catalyst used in the iridium-catalyzed asymmetry hydrogenation of unfunctionalized exocyclic double carbon bonds. Also, it is used to test new NeoPHOX ligands derived from serine or threonine.
Bis(1,5-cyclooctadiene)diiridium(I) dichloride is an acid that can be prepared using a preparative method. It is an organometallic compound that can be used in the cross-coupling of activated terminal alkynes with aryl halides. Bis(1,5-cyclooctadiene)diiridium(I) dichloride has been synthesized by reacting furfural with chloride and acetonitrile. The ligand used was 2,2′-bipyridine. The reaction time to produce bis(1,5-cyclooctadiene)diiridium(I) dichloride is approximately three hours.
, 12112-67-3.

Organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. 12112-67-3, formula is C16H24Cl2Ir2, Name is Chloro(1,5-cyclooctadiene)iridium(I) dimer. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Computed Properties of 12112-67-3.

Fukuyama, Takahide;Hamada, Yuki;Ryu, Ilhyong research published 《 A New Protocol for Catalytic Reduction of Alkyl Chlorides Using an Iridium/Bis(benzimidazol-2′-yl)pyridine Catalyst and Triethylsilane》, the research content is summarized as follows. The reduction of alkyl/aryl chlorides RX (R = n-dodecyl, adamantan-1-yl, naphthalen-1-yl, etc.) using triethylsilane is investigated. Primary, secondary, tertiary, and benzylic C-Cl bonds were effectively converted into C-H bonds using [IrCl(cod)]₂/2,6-bis(benzimidazol-2-yl)pyridine catalyst system. This catalyst system is quite simple since the tridentate N-ligand can be easily prepared in one step from com. available reagents.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Gao, Zhaofeng team published research on Angewandte Chemie, International Edition in 2021 | 12112-67-3

Safety of Chloro(1,5-cyclooctadiene)iridium(I) dimer, Bis(1,5-cyclooctadiene)diiridium(I) is a useful research compound. Its molecular formula is C16H24Cl2Ir2-2 and its molecular weight is 671.7 g/mol. The purity is usually 95%.
Bis(1,5-cyclooctadiene)diiridium(I) Dichloride is a catalyst used in the iridium-catalyzed asymmetry hydrogenation of unfunctionalized exocyclic double carbon bonds. Also, it is used to test new NeoPHOX ligands derived from serine or threonine.
Bis(1,5-cyclooctadiene)diiridium(I) dichloride is an acid that can be prepared using a preparative method. It is an organometallic compound that can be used in the cross-coupling of activated terminal alkynes with aryl halides. Bis(1,5-cyclooctadiene)diiridium(I) dichloride has been synthesized by reacting furfural with chloride and acetonitrile. The ligand used was 2,2′-bipyridine. The reaction time to produce bis(1,5-cyclooctadiene)diiridium(I) dichloride is approximately three hours.
, 12112-67-3.

Gao, Zhaofeng;Liu, Jingwen;Huang, Haizhou;Geng, Huiling;Chang, Mingxin research published 《 An Iridium Catalytic System Compatible with Inorganic and Organic Nitrogen Sources for Dual Asymmetric Reductive Amination Reactions》, the research content is summarized as follows. Herein efforts on merging two asym. reductive amination (ARA) reactions into a single-step transformation was reported. Catalyzed by a complex formed from iridium and a steric hindered phosphoramidite, readily available and inexpensive aromatic ketones initially underwent the first ARA with ammonium acetate to afford primary amines, which served as the amine sources for the second ARA, and finally provided the enantiopure C₂-sym. secondary amine products. The developed process competently enabled the successive coupling of inorganic and organic nitrogen sources with ketones in the same reaction system. The Bronsted acid additive played multiple roles in this procedure: it accelerated the formation of imine intermediates, minimized the inhibitory effect of N-containing species on the iridium catalyst, and reduced the primary amine side products.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Gauthier, Etienne S. team published research on European Journal of Organic Chemistry in 2021 | 12112-67-3

12112-67-3, Bis(1,5-cyclooctadiene)diiridium(I) is a useful research compound. Its molecular formula is C16H24Cl2Ir2-2 and its molecular weight is 671.7 g/mol. The purity is usually 95%.
Bis(1,5-cyclooctadiene)diiridium(I) Dichloride is a catalyst used in the iridium-catalyzed asymmetry hydrogenation of unfunctionalized exocyclic double carbon bonds. Also, it is used to test new NeoPHOX ligands derived from serine or threonine.
Bis(1,5-cyclooctadiene)diiridium(I) dichloride is an acid that can be prepared using a preparative method. It is an organometallic compound that can be used in the cross-coupling of activated terminal alkynes with aryl halides. Bis(1,5-cyclooctadiene)diiridium(I) dichloride has been synthesized by reacting furfural with chloride and acetonitrile. The ligand used was 2,2′-bipyridine. The reaction time to produce bis(1,5-cyclooctadiene)diiridium(I) dichloride is approximately three hours.
, Synthetic Route of 12112-67-3

Gauthier, Etienne S.;Cordier, Marie;Dorcet, Vincent;Vanthuyne, Nicolas;Favereau, Ludovic;Williams, J. A. Gareth;Crassous, Jeanne research published 《 Helically Chiral NHC-Gold(I) Complexes: Synthesis, Chiroptical Properties and Electronic Features of the [5]Helicene-Imidazolylidene Ligand》, the research content is summarized as follows. We describe the preparation of helically chiral gold(I) complexes bearing a [5]helicenic-N-heterocyclic carbene ligand. They were successfully obtained as enantiopure compounds by semi-preparative chiral HPLC and their structural, chiroptical, and photophys. properties were subsequently investigated. Notably, strong electronic CD, dual emission from singlet and triplet states, with the timescale of the latter up to the millisecond range at room temperature, and moderate circularly phosphorescence were observed The σ-donating and π-accepting properties of the constituent helical ortho-fused π-conjugated carbene were investigated by classical quant. anal. of the IR stretching frequencies and NMR characteristics of the corresponding Ir(CO)₂Cl complex and selenourea.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Gillaizeau, Isabelle team published research on European Journal of Organic Chemistry in 2022 | 12112-67-3

Recommanded Product: Chloro(1,5-cyclooctadiene)iridium(I) dimer, Bis(1,5-cyclooctadiene)diiridium(I) is a useful research compound. Its molecular formula is C16H24Cl2Ir2-2 and its molecular weight is 671.7 g/mol. The purity is usually 95%.
Bis(1,5-cyclooctadiene)diiridium(I) Dichloride is a catalyst used in the iridium-catalyzed asymmetry hydrogenation of unfunctionalized exocyclic double carbon bonds. Also, it is used to test new NeoPHOX ligands derived from serine or threonine.
Bis(1,5-cyclooctadiene)diiridium(I) dichloride is an acid that can be prepared using a preparative method. It is an organometallic compound that can be used in the cross-coupling of activated terminal alkynes with aryl halides. Bis(1,5-cyclooctadiene)diiridium(I) dichloride has been synthesized by reacting furfural with chloride and acetonitrile. The ligand used was 2,2′-bipyridine. The reaction time to produce bis(1,5-cyclooctadiene)diiridium(I) dichloride is approximately three hours.
, 12112-67-3.

Chloride substituents modify the physical properties of organic compounds in several ways. 12112-67-3, formula is C16H24Cl2Ir2, Name is Chloro(1,5-cyclooctadiene)iridium(I) dimer. They are typically denser than water due to the presence of chlorine, which has a high atomic weight. Recommanded Product: Chloro(1,5-cyclooctadiene)iridium(I) dimer.

Gillaizeau, Isabelle;Dondasse, Ismael;Nicolas, Cyril;Mimoun, Liliane;Sukach, Volodymyr;Meudal, Herve research published 《 Iridium-Catalyzed β-C(sp²)-H Borylation of Enamides – Access to 3,3-Dihalogeno-2-methoxypiperidines》, the research content is summarized as follows. An efficient catalytic preparation of synthetically useful new α,β-unsaturated β-borylated enamides was achieved under relatively mild conditions via a regioselective iridium-catalyzed C(sp²)-H dehydrogenative borylation of enamides with B₂pin₂. The method features broad substrate scope, good functional group tolerance and efficient scale-up. These C-3 borylated enamides can be advantageously exploited in cross-coupling reactions and converted into valuable 3,3-dihalogeno-2-methoxypiperidines in very short reaction times.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Gonzalez-Lainez, Miguel team published research on Organometallics in 2022 | 12112-67-3

Name: Chloro(1,5-cyclooctadiene)iridium(I) dimer, Bis(1,5-cyclooctadiene)diiridium(I) is a useful research compound. Its molecular formula is C16H24Cl2Ir2-2 and its molecular weight is 671.7 g/mol. The purity is usually 95%.
Bis(1,5-cyclooctadiene)diiridium(I) Dichloride is a catalyst used in the iridium-catalyzed asymmetry hydrogenation of unfunctionalized exocyclic double carbon bonds. Also, it is used to test new NeoPHOX ligands derived from serine or threonine.
Bis(1,5-cyclooctadiene)diiridium(I) dichloride is an acid that can be prepared using a preparative method. It is an organometallic compound that can be used in the cross-coupling of activated terminal alkynes with aryl halides. Bis(1,5-cyclooctadiene)diiridium(I) dichloride has been synthesized by reacting furfural with chloride and acetonitrile. The ligand used was 2,2′-bipyridine. The reaction time to produce bis(1,5-cyclooctadiene)diiridium(I) dichloride is approximately three hours.
, 12112-67-3.

The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 12112-67-3, formula is C16H24Cl2Ir2, Name is Chloro(1,5-cyclooctadiene)iridium(I) dimer. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Name: Chloro(1,5-cyclooctadiene)iridium(I) dimer.

Gonzalez-Lainez, Miguel;Jimenez, M. Victoria;Azpiroz, Ramon;Passarelli, Vincenzo;Modrego, F. Javier;Perez-Torrente, Jesus J. research published 《 N-Methylation of Amines with Methanol Catalyzed by Iridium(I) Complexes Bearing an N,O-Functionalized NHC Ligand》, the research content is summarized as follows. A set of neutral [IrBr(L₂)(κC-^tBuImCH₂PyCH₂OMe)] and cationic [Ir(L₂)(κ²C,N-^tBuImCH₂PyCH₂OMe)]PF₆ (L₂ = cod, (CO)₂) Ir(I) compounds featuring a flexible lutidine-derived polydentate ligand having NHC and -OMe as donor functions were evaluated as catalyst precursors for the N-methylation of aniline using MeOH both as a reducing agent and a C1 source. The carbonyl complexes are somewhat more active than the related diene compounds with the neutral compound [IrBr(CO)₂(κC-^tBuImCH₂PyCH₂OMe)] being the more active. A range of aromatic primary amines, including heterocyclic amines, were selectively transformed into the corresponding N-methylamino derivatives using this catalyst at a low catalyst loading (0.1 mol %) and substoichiometric amounts of Cs₂CO₃ (half equiv) as a base, in MeOH at 423 K. For aliphatic primary amines, selective N,N-dimethylation was achieved under the same catalytic conditions. The unselective deprotonation of the methylene linkers in [IrBr(CO)₂(κC-^tBuImCH₂PyCH₂OMe)] affords two isomeric neutral complexes featuring a coordinated dearomatized pyridine core, which were converted into [Ir(OMe)(CO)₂(κC-^tBuImCH₂PyCH₂OMe)] upon addition of MeOH. This compound undergoes thermal activation of a C-H bond of the tert-Bu group to give the cyclometalated Ir(I) complex [Ir(CO)₂{κ²C,C-(-CH₂Me₂C-ImCH₂PyCH₂OMe)}] featuring a bidentate C,C-coordinated NHC ligand. Mechanistic studies support a borrowing H mechanism proceeding through Ir(I) intermediates with the methoxo complex as the catalytic active species and the cyclometalated complex as the catalyst resting state. D labeling experiments demonstrated that both species are in equilibrium under catalytic conditions, which is consistent with the exhibited catalytic activity of the cyclometalated complex.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Faiges, Jorge team published research on Organometallics in 2021 | 12112-67-3

Faiges, Jorge;Borras, Carlota;Pastor, Isidro M.;Pamies, Oscar;Besora, Maria;Dieguez, Montserrat research published 《 Density Functional Theory-Inspired Design of Ir/P,S-Catalysts for Asymmetric Hydrogenation of Olefins》, the research content is summarized as follows. In silico-based optimization of Ir/P,S-catalysts for the asym. hydrogenation of unfunctionalized olefins using (E)-1-(but-2-en-2-yl)-4-methoxybenzene as a benchmark olefin has been carried out. DFT calculations revealed that the thioether group has a major role in directing the olefin coordination. This, together with the configuration of the biphenyl phosphite group, has an impact in maximizing the energy gap between the most stable transition states leading to opposite enantiomers. As a result, the optimized catalyst proved to be efficient in the hydrogenation of a range of alkenes with the same substitution pattern and olefin geometry as the benchmark olefin, regardless of the presence of functional groups with different coordination abilities (ee values up to 97%). Appealingly, further modifications at the thioether groups and at the biaryl phosphite moiety allowed the highly enantioselective hydrogenation of olefins with different substitution patterns (e.g., α,β-unsaturated lactones and lactams, 1,1′-disubstituted enol phosphinates, and cyclic β-enamides; ee values up to >99%).

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Fernando, Nathalie K. team published research on Journal of Physical Chemistry A in 2021 | 12112-67-3

Fernando, Nathalie K.;Cairns, Andrew B.;Murray, Claire A.;Thompson, Amber L.;Dickerson, Joshua L.;Garman, Elspeth F.;Ahmed, Nayera;Ratcliff, Laura E.;Regoutz, Anna research published 《 Structural and Electronic Effects of X-ray Irradiation on Prototypical [M(COD)Cl]₂ Catalysts》, the research content is summarized as follows. X-ray characterization techniques are invaluable for probing material characteristics and properties, and have been instrumental in discoveries across materials research. However, there is a current lack of understanding of how X-ray-induced effects manifest in small mol. crystals. This is of particular concern as new X-ray sources with ever-increasing brilliance are developed. In this paper, systematic studies of X-ray-matter interactions are reported on two industrially important catalysts, [Ir(COD)Cl]₂ and [Rh(COD)Cl]₂, exposed to radiation in X-ray diffraction (XRD) and XPS experiments From these complementary techniques, changes to structure, chem. environments, and electronic structure are observed as a function of X-ray exposure, allowing comparisons of stability to be made between the two catalysts. Radiation dose is estimated using recent developments to the RADDOSE-3D software for small mols. and applied to powder XRD and XPS experiments Further insights into the electronic structure of the catalysts and changes occurring as a result of the irradiation are drawn from d. functional theory (DFT). The techniques combined here offer much needed insight into the X-ray-induced effects in transition-metal catalysts and, consequently, their intrinsic stabilities. There is enormous potential to extend the application of these methods to other small mol. systems of scientific or industrial relevance.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Frost, James R. team published research on Tetrahedron in 2021 | 12112-67-3

Frost, James R.;Cheong, Choon Boon;Akhtar, Wasim M.;Caputo, Dimitri F. J.;Christensen, Kirsten E.;Stevenson, Neil G.;Donohoe, Timothy J. research published 《 Hydrogen borrowing catalysis using 1° and 2° alcohols: Investigation and scope leading to α and β branched products》, the research content is summarized as follows. The alkylation of a variety of ketones, e.g., 1-cyclopropyl-3-(furan-2-yl)propan-1-one using 1° R¹OH (R¹ = n-Bu, Bn, cyclopropylmethyl, etc.) or 2° alcs. R²R³CHOH (R² = Me, Et; R³ = Et, Ph, thiophen-2-yl, cyclobutyl, etc.; R²R³ = cyclohexyl, 1,4-dioxaspiro[4.5]decan-8-yl, cyclopentyl, etc.) under hydrogen borrowing catalysis is described. Initial research focused on the α-alkylation of cyclopropyl ketones with higher 1° alcs. (i.e. larger than MeOH), leading to the formation of α-branched products, e.g., 1-cyclopropyl-2-(furan-2-ylmethyl)hexan-1-one. The search for addnl. substrates with which to explore this chem. led to discover that di-ortho-substituted aryl ketones were also privileged scaffolds, with Ph^* (C₆Me₅) ketones being the optimal choice. Further investigations revealed that this motif was crucial for alkylation with 2° alcs. forming β-branched products, which also provided an opportunity to study diastereoselective and intramol. hydrogen borrowing processes.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Di Girolamo, Alessandro team published research on Inorganic Chemistry in 2022 | 12112-67-3

Di Girolamo, Alessandro;Monti, Filippo;Mazzanti, Andrea;Matteucci, Elia;Armaroli, Nicola;Sambri, Letizia;Baschieri, Andrea research published 《 4-Phenyl-1,2,3-triazoles as Versatile Ligands for Cationic Cyclometalated Iridium(III) Complexes》, the research content is summarized as follows. Five cationic iridium(III) complexes were synthesized exploiting two triazole-based cyclometalating ligands, namely, 1-methyl-4-phenyl-1H-1,2,3-triazole (A) and the corresponding mesoionic carbene 1,3-dimethyl-4-phenyl-1H-1,2,3-triazol-5-ylidene (B). From the combination of these two ligands and the ancillary one, i.e., 4,4′-di-tert-butyl-2,2′-bipyridine or tert-Bu isocyanide ), not only the typical bis-heteroleptic complexes but also the much less explored tris-heteroleptic analogs could be synthesized. The redox and emission properties of all of the complexes are effectively fine-tuned by the different ligands: (i) cyclometalating ligand A induces a stronger HOMO stabilization compared to B and leads to complexes with progressively narrower HOMO-LUMO and redox gaps, and lower emission energy; (ii) complexes, equipped with the bipyridine ancillary ligand, display fully reversible redox processes and emit from predominantly metal-to-ligand charge transfer (MLCT) states with high emission quantum yields, up to 60% in polymeric matrix; (iii) complexes and , equipped with high-field isocyanide ligands, display irreversible redox processes and high-energy emission from strongly ligand-centered triplets with long emission lifetimes but relatively low quantum yields (below 6%, both in room-temperature solution and in solid state). This work demonstrates the versatility of phenyl-triazole derivatives as cyclometalating ligands with different chelation modes (i.e.,C N and C C;)thesis of photoactive iridium(III) complexes with highly tunable properties.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics