M.W=650-700 Archives - Page 14 of 15 - Chlorides-buliding-blocks

Ding, Huan team published research on Journal of Organic Chemistry in 2022 | 12112-67-3

12112-67-3, Bis(1,5-cyclooctadiene)diiridium(I) is a useful research compound. Its molecular formula is C16H24Cl2Ir2-2 and its molecular weight is 671.7 g/mol. The purity is usually 95%.
Bis(1,5-cyclooctadiene)diiridium(I) Dichloride is a catalyst used in the iridium-catalyzed asymmetry hydrogenation of unfunctionalized exocyclic double carbon bonds. Also, it is used to test new NeoPHOX ligands derived from serine or threonine.
Bis(1,5-cyclooctadiene)diiridium(I) dichloride is an acid that can be prepared using a preparative method. It is an organometallic compound that can be used in the cross-coupling of activated terminal alkynes with aryl halides. Bis(1,5-cyclooctadiene)diiridium(I) dichloride has been synthesized by reacting furfural with chloride and acetonitrile. The ligand used was 2,2′-bipyridine. The reaction time to produce bis(1,5-cyclooctadiene)diiridium(I) dichloride is approximately three hours.
, Category: chlorides-buliding-blocks

Chlorinated organic compounds are found in nearly every class of biomolecules. 12112-67-3, formula is C16H24Cl2Ir2, Name is Chloro(1,5-cyclooctadiene)iridium(I) dimer. Alkyl chlorides, as versatile building blocks in organic chemistry, are used in the preparation of alcohols, thioethers, alkenes, alkynes, esters, and Grignard reagents. Category: chlorides-buliding-blocks.

Ding, Huan;Gao, Weiwei;Yu, Tian;Wang, Zhen;Gou, Fuqi;Ding, Shengtao research published 《 Hydroboration and Diboration of Internal Alkynes under Iridium Catalysis》, the research content is summarized as follows. Here we demonstrate the feasibility and efficiency of simple iridium-based catalytic systems in the synthesis of multisubstituted alkenyl boronates from internal alkynes with high selectivities. A variety of alkynes were smoothly decorated with HBpin under a mild [Ir(cod)Cl]₂/dppm/acetone condition to afford trisubstituted alkenyl boronic esters with up to >99:1 regioselectivity. The diboration reaction could effectively occur in the presence of [Ir(cod)Cl]₂/DCM. Plausible mechanisms were provided to illustrate these two catalytic processes, in which the intrinsic functional group of the alkyne was supposed to be important in facilitating these reactions as well as the regioselectivity.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Ding, Lu team published research on Journal of the American Chemical Society in 2022 | 12112-67-3

Electric Literature of 12112-67-3, Bis(1,5-cyclooctadiene)diiridium(I) is a useful research compound. Its molecular formula is C16H24Cl2Ir2-2 and its molecular weight is 671.7 g/mol. The purity is usually 95%.
Bis(1,5-cyclooctadiene)diiridium(I) Dichloride is a catalyst used in the iridium-catalyzed asymmetry hydrogenation of unfunctionalized exocyclic double carbon bonds. Also, it is used to test new NeoPHOX ligands derived from serine or threonine.
Bis(1,5-cyclooctadiene)diiridium(I) dichloride is an acid that can be prepared using a preparative method. It is an organometallic compound that can be used in the cross-coupling of activated terminal alkynes with aryl halides. Bis(1,5-cyclooctadiene)diiridium(I) dichloride has been synthesized by reacting furfural with chloride and acetonitrile. The ligand used was 2,2′-bipyridine. The reaction time to produce bis(1,5-cyclooctadiene)diiridium(I) dichloride is approximately three hours.
, 12112-67-3.

Ding, Lu;Song, Hao;Zheng, Chao;You, Shu-Li research published 《 Enantioselective Synthesis of Medium-Sized-Ring Lactones via Iridium-Catalyzed Z-Retentive Asymmetric Allylic Substitution Reaction》, the research content is summarized as follows. An enantioselective synthesis of medium-sized-ring lactones, e.g., I, by iridium-catalyzed Z-retentive asym. allylic substitution reaction was reported. The reaction features mild conditions and a broad substrate scope. Various eight- to 11-membered-ring lactones can be afforded in moderate to excellent yields (up to 88%) and excellent enantioselectivity (up to 99% ee). The utilization of both Z-allyl precursors and Ir catalyst is critical for the medium-sized ring formation.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Do, Thomas H. team published research on Inorganic Chemistry in 2022 | 12112-67-3

The class of organic compounds having covalently a bonded chlorine atom is called organic chlorides. 12112-67-3, formula is C16H24Cl2Ir2, Name is Chloro(1,5-cyclooctadiene)iridium(I) dimer. Their wide structural variety and divergent chemical properties lead to a broad range of named reactions and applications. Computed Properties of 12112-67-3.

Do, Thomas H.;Brown, Seth N. research published 《 Mono- and Bis(iminoxolene)iridium Complexes: Synthesis and Covalency in π Bonding》, the research content is summarized as follows. N-(2,6-Diisopropylphenyl)-4,6-di-tert-butyl-o-iminobenzoquinone (Diso) reacts with the (cyclooctadiene)iridium chloride dimer to form a monoiminoxolene complex, (Diso)Ir(cod)Cl. Reaction of 2 equivalent of the iminoquinone with chlorobis(cyclooctene)iridium dimer affords the bis-iminoxolene (Diso)₂IrCl. This five-coordinate complex adopts a distorted square pyramidal structure with an apical chloride ligand and undergoes halide exchange to form an air-stable iodide complex. (Diso)₂IrCl can be reduced by one electron to form neutral, square planar (Diso)₂Ir, while oxidation with PhICl₂ gives octahedral trans-(Diso)₂IrCl₂. The cis isomer can be prepared by air oxidation of (Diso)₂IrCl; cis/trans isomerization is not observed even on prolonged heating. Structural and spectroscopic features of the complexes are consistent with the presence of strong, covalent π bonding between the metal and the iminoxolene ligands, with structural data suggesting between 45 and 60% iridium character in the π bonding orbitals, depending on the ancillary ligands. The spectroscopic similarity of (Diso)₂Ir and (Diso)₂IrCl to their cobalt congeners suggests that the first-row metal complexes likewise have appreciably covalent metal-iminoxolene π bonds.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Duan, Xuelun team published research on Chinese Chemical Letters in 2021 | 12112-67-3

Safety of Chloro(1,5-cyclooctadiene)iridium(I) dimer, Bis(1,5-cyclooctadiene)diiridium(I) is a useful research compound. Its molecular formula is C16H24Cl2Ir2-2 and its molecular weight is 671.7 g/mol. The purity is usually 95%.
Bis(1,5-cyclooctadiene)diiridium(I) Dichloride is a catalyst used in the iridium-catalyzed asymmetry hydrogenation of unfunctionalized exocyclic double carbon bonds. Also, it is used to test new NeoPHOX ligands derived from serine or threonine.
Bis(1,5-cyclooctadiene)diiridium(I) dichloride is an acid that can be prepared using a preparative method. It is an organometallic compound that can be used in the cross-coupling of activated terminal alkynes with aryl halides. Bis(1,5-cyclooctadiene)diiridium(I) dichloride has been synthesized by reacting furfural with chloride and acetonitrile. The ligand used was 2,2′-bipyridine. The reaction time to produce bis(1,5-cyclooctadiene)diiridium(I) dichloride is approximately three hours.
, 12112-67-3.

Duan, Xuelun;Zheng, Nan;Li, Ming;Sun, Xinhao;Lin, Zhuye;Qiu, Pan;Song, Wangze research published 《 Remote ether groups-directed regioselective and chemoselective cycloaddition of azides and alkynes》, the research content is summarized as follows. Remote ether groups could be used as directing groups to prepare fully substituted 5-ether-1,2,3-triazoles with exclusive 1,5-regioselectivities and excellent chemoselectivities. Ether group could coordinate with iridium catalyst by lone-pair electron at a distance (up to four σ bonds) away from alkyne to control the regioselectivity by weak coordination effect. The cycloaddition reaction chemoselectively occurred at the propargyl ether moiety of diyne to give unique fully substituted 4-alkynyl-triazole.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Durran, Sean E. team published research on European Journal of Inorganic Chemistry in 2021 | 12112-67-3

Name: Chloro(1,5-cyclooctadiene)iridium(I) dimer, Bis(1,5-cyclooctadiene)diiridium(I) is a useful research compound. Its molecular formula is C16H24Cl2Ir2-2 and its molecular weight is 671.7 g/mol. The purity is usually 95%.
Bis(1,5-cyclooctadiene)diiridium(I) Dichloride is a catalyst used in the iridium-catalyzed asymmetry hydrogenation of unfunctionalized exocyclic double carbon bonds. Also, it is used to test new NeoPHOX ligands derived from serine or threonine.
Bis(1,5-cyclooctadiene)diiridium(I) dichloride is an acid that can be prepared using a preparative method. It is an organometallic compound that can be used in the cross-coupling of activated terminal alkynes with aryl halides. Bis(1,5-cyclooctadiene)diiridium(I) dichloride has been synthesized by reacting furfural with chloride and acetonitrile. The ligand used was 2,2′-bipyridine. The reaction time to produce bis(1,5-cyclooctadiene)diiridium(I) dichloride is approximately three hours.
, 12112-67-3.

Organic chloride is an organic compound containing at least one covalently bonded atom of chlorine. 12112-67-3, formula is C16H24Cl2Ir2, Name is Chloro(1,5-cyclooctadiene)iridium(I) dimer. Their wide structural variety and divergent chemical properties lead to a broad range of names and applications. Name: Chloro(1,5-cyclooctadiene)iridium(I) dimer.

Durran, Sean E.;Elsegood, Mark R. J.;Noble, Thomas A.;Smith, Martin B.;Gelbrich, Thomas;Hursthouse, Michael B.;Light, Mark E. research published 《 Synthesis and Characterisation of Transition Metal Complexes of a Novel 1,5-benzodiazepine-Functionalised Tertiary Phosphine》, the research content is summarized as follows. The 1-step synthesis (44% isolated yield) of the 1,5-benzodiazapine functionalized phosphine 1, C₃₁H₃₁N₂OP, is reported. Bridge cleavage of {MCl(μ-Cl)(η⁵-Cp^*)}₂ (M = Ir, Rh) with 2 equiv of 1 in CH₂Cl₂ gave mononuclear [MCl₂(η⁵-Cp^*)(P-1)] (M = Ir, 2a; M = Rh, 2b) in which 1 functions as a P-monodentate ligand. Rapid C(sp³)-H bond activation, at room temperature, is observed for 2a leading to the unusual cyclometalated complex [Ir(η⁵-Cp^*)(P,N,C-1)]Cl₂ 3 (or 3‘) bearing an anionic P/N_amine/C-terdentate ligand. Reaction of [PtMeCl(η⁴-cod)] with one equivalent of 1 led to [PtMeCl(P,N-1)] 4, suggesting that 3 may form via an intermediate Ir(III) cationic species in which the ligand is P,N-bound. The Ir^I complex [IrCl(η⁴-cod)(P-1)] 5 does not, under similar conditions, show any evidence for C-H activation. Single crystal x-ray studies on 1, 2a, 2b, 3, 3‘, 4, and 5 reveal intramol. N ··· H-O H-bonding in all cases.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Daubit, Isabelle Marie team published research on Chemistry – A European Journal in 2021 | 12112-67-3

Daubit, Isabelle Marie;Wortmann, Svenja;Siegmund, Daniel;Hahn, Stephan;Nuernberger, Patrick;Metzler-Nolte, Nils research published 《 Unveiling Luminescent Ir(I) and Rh(I) N-Heterocyclic Carbene Complexes: Structure, Photophysical Specifics, and Cellular Localization in the Endoplasmic Reticulum》, the research content is summarized as follows. Complexes of Rh(I) and Ir(I) of the [M(COD)(NHC)X] type (M = Rh or Ir, COD = 1,5-cyclooctadiene, NHC = N-heterocyclic carbene, and X = halide) have recently shown promising cytotoxic activities against several cancer cell lines. Initial mechanism of action studies provided some knowledge about their interaction with DNA and proteins. However, information about their cellular localization remains scarce owing to luminescence quenching within this complex type. Herein, the synthesis of two rare examples of luminescent Rh(I) and Ir(I) [M(COD)(NHC)I] complexes with 1,8-naphthalimide-based emitting ligands is reported. All new complexes are comprehensively characterized, including with single-crystal x-ray structures. Steric crowding in one derivative leads to two distinct rotamers in solution, which apparently can be distinguished both by pronounced NMR shifts and by their resp. spectral and temporal emission signatures. When the photophys. properties of these new complexes are exploited for cellular imaging in HT-29 and PT-45 cancer cell lines, the complexes accumulate predominantly in the endoplasmic reticulum, which is an entirely new finding and provides the 1st insight into the cellular localization of such Ir(I)(NHC) complexes.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Daubit, Isabelle Marie team published research on Chemistry – A European Journal in 2021 | 12112-67-3

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Chen, Qi team published research on Journal of the American Chemical Society in 2021 | 12112-67-3

SDS of cas: 12112-67-3, Bis(1,5-cyclooctadiene)diiridium(I) is a useful research compound. Its molecular formula is C16H24Cl2Ir2-2 and its molecular weight is 671.7 g/mol. The purity is usually 95%.
Bis(1,5-cyclooctadiene)diiridium(I) Dichloride is a catalyst used in the iridium-catalyzed asymmetry hydrogenation of unfunctionalized exocyclic double carbon bonds. Also, it is used to test new NeoPHOX ligands derived from serine or threonine.
Bis(1,5-cyclooctadiene)diiridium(I) dichloride is an acid that can be prepared using a preparative method. It is an organometallic compound that can be used in the cross-coupling of activated terminal alkynes with aryl halides. Bis(1,5-cyclooctadiene)diiridium(I) dichloride has been synthesized by reacting furfural with chloride and acetonitrile. The ligand used was 2,2′-bipyridine. The reaction time to produce bis(1,5-cyclooctadiene)diiridium(I) dichloride is approximately three hours.
, 12112-67-3.

Chen, Qi;Liu, Qing;Xiao, Jie;Leng, Xuebing;Deng, Liang research published 《 Catalytic Method for the Synthesis of Deuterium-Labeled N-Heterocyclic Carbenes Enabled by a Coordinatively Unsaturated Ruthenium N-Heterocyclic Carbene Catalyst》, the research content is summarized as follows. The wide usage of N-heterocyclic carbenes (NHCs) has raised the quest for their deuterated mols. Effective synthesis method to obtain them, however, has remained elusive. We present here a catalytic method for the preparation of deuterated NHCs, namely, the catalytic hydrogen-deuterium exchange reaction between NHCs and deuterated benzene using a coordinatively unsaturated Ru NHC catalyst. The catalytic system enables selective deuteration of the C(sp³)-H bonds of the alkyl groups on N-substituents, as well as the sterically nonhindered C(sp²)-H bonds of NHCs as demonstrated by the preparation of 16 deuterium-labeled NHCs that have a deuteration ratio on specified sites higher than 90%. The gram-scale synthesis of deuterated IMes indicated the applicability of this catalytic method. Mechanistic studies revealed that the high regio-selectivity toward those C(sp³)-H bonds on NHCs originates from the regio-selectivity of cyclometalation reactions of coordinatively unsaturated Ru NHC species.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Crisenza, Giacomo E. M. team published research on Nature Chemistry in 2021 | 12112-67-3

Recommanded Product: Chloro(1,5-cyclooctadiene)iridium(I) dimer, Bis(1,5-cyclooctadiene)diiridium(I) is a useful research compound. Its molecular formula is C16H24Cl2Ir2-2 and its molecular weight is 671.7 g/mol. The purity is usually 95%.
Bis(1,5-cyclooctadiene)diiridium(I) Dichloride is a catalyst used in the iridium-catalyzed asymmetry hydrogenation of unfunctionalized exocyclic double carbon bonds. Also, it is used to test new NeoPHOX ligands derived from serine or threonine.
Bis(1,5-cyclooctadiene)diiridium(I) dichloride is an acid that can be prepared using a preparative method. It is an organometallic compound that can be used in the cross-coupling of activated terminal alkynes with aryl halides. Bis(1,5-cyclooctadiene)diiridium(I) dichloride has been synthesized by reacting furfural with chloride and acetonitrile. The ligand used was 2,2′-bipyridine. The reaction time to produce bis(1,5-cyclooctadiene)diiridium(I) dichloride is approximately three hours.
, 12112-67-3.

Crisenza, Giacomo E. M.;Faraone, Adriana;Gandolfo, Eugenio;Mazzarella, Daniele;Melchiorre, Paolo research published 《 Catalytic asymmetric C-C cross-couplings enabled by photoexcitation》, the research content is summarized as follows. Here, authors show how by simply using visible light can divert the established ionic reactivity of a chiral allyl-iridium(III) complex to switch on completely new catalytic functions, enabling mechanistically unrelated radical-based enantioselective pathways. Photoexcitation provides the chiral organometallic intermediate with the ability to activate substrates via an electron-transfer manifold. This redox event unlocks an otherwise inaccessible cross-coupling mechanism, since the resulting iridium(II) center can intercept the generated radicals and underwent a reductive elimination to forge a stereogenic center with high stereoselectivity. This photochem. strategy enables difficult-to-realize enantioselective alkyl-alkyl cross-coupling reactions between allylic alcs. and readily available radical precursors, which are not achievable under thermal activation.

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics

Canadas, Purificacion team published research on Inorganic Chemistry in 2022 | 12112-67-3

Reference of 12112-67-3, Bis(1,5-cyclooctadiene)diiridium(I) is a useful research compound. Its molecular formula is C16H24Cl2Ir2-2 and its molecular weight is 671.7 g/mol. The purity is usually 95%.
Bis(1,5-cyclooctadiene)diiridium(I) Dichloride is a catalyst used in the iridium-catalyzed asymmetry hydrogenation of unfunctionalized exocyclic double carbon bonds. Also, it is used to test new NeoPHOX ligands derived from serine or threonine.
Bis(1,5-cyclooctadiene)diiridium(I) dichloride is an acid that can be prepared using a preparative method. It is an organometallic compound that can be used in the cross-coupling of activated terminal alkynes with aryl halides. Bis(1,5-cyclooctadiene)diiridium(I) dichloride has been synthesized by reacting furfural with chloride and acetonitrile. The ligand used was 2,2′-bipyridine. The reaction time to produce bis(1,5-cyclooctadiene)diiridium(I) dichloride is approximately three hours.
, 12112-67-3.

Canadas, Purificacion;Diaz, Jesus;Perez, Julio;Riera, Lucia research published 《 Strongly Electron-Donating Triazolylidene Ligands: Cationic Metal Carbonyl Complexes of 1-Methyl-1,2,3-triazole as Triazolium Surrogates》, the research content is summarized as follows. A new strategy for tuning the electronic properties of 1,2,3-triazol-5-ylidene metal complexes is reported using {Mo(η³-C₄H₇)(bipy)(CO)₂} or {Re(bipy)(CO)₃} fragments as substituents at the triazole N3 atom. Reaction of cationic Mo(II) and Re(I) 1-methyl-1,2,3-triazole compounds with the strong base KN(SiMe₃)₂ in the presence of electrophilic metal fragments, such as AgOTf (OTf = trifluoromethanesufonate) or [CuCl(IPr)] (IPr = 2,6-(diisopropyl)phenylimidazol-2-ylidene) affords a new type of 1,2,3-triazol-5-ylidene complexes. For Ag(I) cationic bis(triazolylidene)complexes [Ag(tzNHC^M)₂]OTf (M = [Mo], 2; [Re], 4) were obtained, whereas in the case of Cu(I) mixed normal/mesoionic NHC complexes [Cu(IPr)(tzNHC^M)]OTf (M = [Mo], 7; [Re], 8) are formed. This special type of mesoionic N-heterocyclic carbenes bear a metal fragment at the N3 atom of the 1,2,3-triazole moiety, showing a notable enhancement of the carbene electron donor ability compared to conventional alkyl-substituted analogs. Transmetalation from cationic Ag bis(triazolylidene) complexes 2 and 4, prepared using this methodol., proved to be very efficient toward [M’Cl(cod)]₂ (M’ = Rh, Ir; cod = cyclooctadiene), affording the corresponding cationic bis(triazolylidene) [M'(cod)(tzNHC^M)₂]OTf (9–12) complexes. The subsequent reaction with CO(g) produces easily the substitution of the diene ligand, affording the corresponding cis-dicarbonyl [M'(CO)₂(tzNHC^M)₂]OTf (13–16) compounds

Referemce:
Chloride – Wikipedia,
Chlorides – an overview | ScienceDirect Topics